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Gene Ontology Browser
Term Detail
GO term:serine-type endopeptidase inhibitor activity
Synonym: serine protease inhibitor activity
Synonym: serine proteinase inhibitor activity
Synonym: serpin activity
GO id:GO:0004867
Definition:Stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme.
Number of paths to term: 3

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship

Gene_Ontology
        is-amolecular_function
                is-aenzyme regulator activity
                        is-aenzyme inhibitor activity
                                is-apeptidase inhibitor activity
                                        is-aendopeptidase inhibitor activity
                                                is-aaspartic-type endopeptidase inhibitor activity
                                                is-acysteine-type endopeptidase inhibitor activity +
                                                is-ametalloendopeptidase inhibitor activity
                                                is-aserine-type endopeptidase inhibitor activity [GO:0004867] (113 genes, 131 annotations)

Gene_Ontology
        is-amolecular_function
                is-aenzyme regulator activity
                        is-apeptidase regulator activity
                                is-aendopeptidase regulator activity
                                        is-aendopeptidase inhibitor activity
                                                is-aaspartic-type endopeptidase inhibitor activity
                                                is-acysteine-type endopeptidase inhibitor activity +
                                                is-ametalloendopeptidase inhibitor activity
                                                is-aserine-type endopeptidase inhibitor activity [GO:0004867] (113 genes, 131 annotations)

Gene_Ontology
        is-amolecular_function
                is-aenzyme regulator activity
                        is-apeptidase regulator activity
                                is-apeptidase inhibitor activity
                                        is-aendopeptidase inhibitor activity
                                                is-aaspartic-type endopeptidase inhibitor activity
                                                is-acysteine-type endopeptidase inhibitor activity +
                                                is-ametalloendopeptidase inhibitor activity
                                                is-aserine-type endopeptidase inhibitor activity [GO:0004867] (113 genes, 131 annotations)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Send questions and comments to User Support. 		last database update
05/08/2013
MGI 5.13 		The Jackson Laboratory