Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SERPINB9
  • Mouse genes Serpinb9
  • Rat genes Serpinb9
  • Zfish genes serpinb14,serpinb1l1,serpinb1l4,zgc:173729
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Serpinb9

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	SERPINB9	IDA		Human	PMID:10790428
Molecular Function	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	SERPINB9	IMP		Human	PMID:17479112
Molecular Function	GO:0002020	protease binding	SERPINB9	IPI	UniProtKB:P10144	Human	PMID:16267761
Molecular Function	GO:0005515	protein binding	SERPINB9	IPI	UniProtKB:Q14790	Human	PMID:17479112
Molecular Function	GO:0005515	protein binding	SERPINB9	IPI	UniProtKB:Q92851	Human	PMID:17479112
Molecular Function	GO:0005515	protein binding	SERPINB9	IPI	UniProtKB:O00463	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SERPINB9	IPI	UniProtKB:O00463	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Serpinb9	IPI	PR:P04187	Mouse	PMID:16618603
Molecular Function	GO:0005515	protein binding	Serpinb9	IPI	PR:P04187	Mouse	PMID:15454490
Molecular Function	GO:0004867	serine-type endopeptidase inhibitor activity	SERPINB9	IDA		Human	PMID:11485349
Molecular Function	GO:0004867	serine-type endopeptidase inhibitor activity	SERPINB9	IDA		Human	PMID:8910377
Molecular Function	GO:0004867	serine-type endopeptidase inhibitor activity	Serpinb9	IMP	MGI:MGI:3687210	Mouse	PMID:17878334
Molecular Function	GO:0004867	serine-type endopeptidase inhibitor activity	Serpinb9	IMP	MGI:MGI:3687210	Mouse	PMID:16618603
Cellular Component	GO:0062023	collagen-containing extracellular matrix	SERPINB9	HDA		Human	PMID:28344315
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Serpinb9	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0005737	cytoplasm	SERPINB9	IDA		Human	PMID:11463822
Cellular Component	GO:0005737	cytoplasm	SERPINB9	IDA		Human	PMID:15739160
Cellular Component	GO:0005737	cytoplasm	Serpinb9	IDA		Mouse	PMID:16618603
Cellular Component	GO:0005829	cytosol	SERPINB9	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	SERPINB9	IDA		Human	PMID:11485349
Cellular Component	GO:0070062	extracellular exosome	SERPINB9	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	SERPINB9	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	SERPINB9	IDA		Human	PMID:16267761
Cellular Component	GO:0005794	Golgi apparatus	SERPINB9	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	SERPINB9	HDA		Human	PMID:19946888
Cellular Component	GO:0005654	nucleoplasm	SERPINB9	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SERPINB9	IDA		Human	PMID:11463822
Cellular Component	GO:0005634	nucleus	SERPINB9	IDA		Human	PMID:11485349
Biological Process	GO:0002438	acute inflammatory response to antigenic stimulus	Serpinb9	IMP	MGI:MGI:3687210	Mouse	PMID:17878334
Biological Process	GO:0071391	cellular response to estrogen stimulus	SERPINB9	IEP		Human	PMID:17237823
Biological Process	GO:0042742	defense response to bacterium	Serpinb9	IMP	MGI:MGI:3687210	Mouse	PMID:17878334
Biological Process	GO:0006955	immune response	SERPINB9	IDA		Human	PMID:16306080
Biological Process	GO:0002448	mast cell mediated immunity	SERPINB9	IEP		Human	PMID:15739160
Biological Process	GO:0043066	negative regulation of apoptotic process	SERPINB9	IMP		Human	PMID:17237823
Biological Process	GO:0043066	negative regulation of apoptotic process	SERPINB9	IMP		Human	PMID:17479112
Biological Process	GO:0043066	negative regulation of apoptotic process	Serpinb9	IDA		Mouse	PMID:15454490
Biological Process	GO:0010951	negative regulation of endopeptidase activity	SERPINB9	IMP		Human	PMID:21795594
Biological Process	GO:0070233	negative regulation of T cell apoptotic process	Serpinb9	IMP	MGI:MGI:3687210	Mouse	PMID:16618603
Biological Process	GO:0042270	protection from natural killer cell mediated cytotoxicity	SERPINB9	IMP		Human	PMID:21795594
Biological Process	GO:0001913	T cell mediated cytotoxicity	Serpinb9	IMP	MGI:MGI:3687210	Mouse	PMID:16618603

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern