|Human Homolog||SERPINB9, serpin peptidase inhibitor, clade B (ovalbumin), member 9|
|NCBI Gene ID||5272|
|Human Synonyms||CAP3, CAP-3, PI9, PI-9|
|Human Chr (Location)||6p25; chr6:2887265-2903312 (-) GRCh38|
Homozygous null mice show defective CTL immunity and clearance of LCMV. Following infection with LCMV or L. monocytogenes, mutant CTLs display a breakdown of cytotoxic granule integrity, increased cytoplasmic granzyme B, and reduced survival due to increased granzyme B-mediated apoptosis.
|Process||acute inflammatory response to antigenic stimulus, defense response to bacterium, ...|
|Component||cytoplasm, cytosol, ...|
|Function||cysteine-type endopeptidase inhibitor activity involved in apoptotic process, protease binding, ...|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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