About   Help   FAQ
Gene Ontology Browser
Term Detail
GO term:negative regulation of endopeptidase activity
GO id:GO:0010951
Definition:Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.
Number of paths to term: 41

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of catalytic activity
                                                is-anegative regulation of catalytic activity
                                                        is-anegative regulation of hydrolase activity
                                                                is-anegative regulation of peptidase activity
                                                                        is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of serine-type endopeptidase activity
                                                                        is-anegative regulation of peptidase activity in other organism +
                                                                        is-anegative regulation of serine-type peptidase activity +
                                                                        is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of catalytic activity
                                                is-aregulation of hydrolase activity
                                                        is-anegative regulation of hydrolase activity
                                                                is-anegative regulation of peptidase activity
                                                                        is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of serine-type endopeptidase activity
                                                                        is-anegative regulation of peptidase activity in other organism +
                                                                        is-anegative regulation of serine-type peptidase activity +
                                                                        is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of catalytic activity
                                                is-aregulation of hydrolase activity
                                                        is-aregulation of peptidase activity
                                                                is-anegative regulation of peptidase activity
                                                                        is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of serine-type endopeptidase activity
                                                                        is-anegative regulation of peptidase activity in other organism +
                                                                        is-anegative regulation of serine-type peptidase activity +
                                                                        is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of catalytic activity
                                                is-aregulation of hydrolase activity
                                                        is-aregulation of peptidase activity
                                                                is-aregulation of endopeptidase activity
                                                                        is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of serine-type endopeptidase activity
                                                                        is-apositive regulation of endopeptidase activity +
                                                                        is-aregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                        is-aregulation of cysteine-type endopeptidase activity +
                                                                        is-aregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                        is-aregulation of serine-type endopeptidase activity +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of macromolecule metabolic process
                                                is-aregulation of protein metabolic process
                                                        is-aregulation of proteolysis
                                                                is-aregulation of peptidase activity
                                                                        is-anegative regulation of peptidase activity
                                                                                is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                        is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                        is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                        is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                        is-anegative regulation of serine-type endopeptidase activity
                                                                                is-anegative regulation of peptidase activity in other organism +
                                                                                is-anegative regulation of serine-type peptidase activity +
                                                                                is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of macromolecule metabolic process
                                                is-aregulation of protein metabolic process
                                                        is-aregulation of proteolysis
                                                                is-aregulation of peptidase activity
                                                                        is-aregulation of endopeptidase activity
                                                                                is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                        is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                        is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                        is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                        is-anegative regulation of serine-type endopeptidase activity
                                                                                is-apositive regulation of endopeptidase activity +
                                                                                is-aregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                                is-aregulation of cysteine-type endopeptidase activity +
                                                                                is-aregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                                is-aregulation of serine-type endopeptidase activity +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of primary metabolic process
                                                is-aregulation of protein metabolic process
                                                        is-aregulation of proteolysis
                                                                is-aregulation of peptidase activity
                                                                        is-anegative regulation of peptidase activity
                                                                                is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                        is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                        is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                        is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                        is-anegative regulation of serine-type endopeptidase activity
                                                                                is-anegative regulation of peptidase activity in other organism +
                                                                                is-anegative regulation of serine-type peptidase activity +
                                                                                is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of primary metabolic process
                                                is-aregulation of protein metabolic process
                                                        is-aregulation of proteolysis
                                                                is-aregulation of peptidase activity
                                                                        is-aregulation of endopeptidase activity
                                                                                is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                        is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                        is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                        is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                        is-anegative regulation of serine-type endopeptidase activity
                                                                                is-apositive regulation of endopeptidase activity +
                                                                                is-aregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                                is-aregulation of cysteine-type endopeptidase activity +
                                                                                is-aregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                                is-aregulation of serine-type endopeptidase activity +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of molecular function
                                is-anegative regulation of molecular function
                                        is-anegative regulation of catalytic activity
                                                is-anegative regulation of hydrolase activity
                                                        is-anegative regulation of peptidase activity
                                                                is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                        is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of cysteine-type endopeptidase activity +
                                                                        is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of serine-type endopeptidase activity
                                                                is-anegative regulation of peptidase activity in other organism +
                                                                is-anegative regulation of serine-type peptidase activity +
                                                                is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of molecular function
                                is-aregulation of catalytic activity
                                        is-anegative regulation of catalytic activity
                                                is-anegative regulation of hydrolase activity
                                                        is-anegative regulation of peptidase activity
                                                                is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                        is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of cysteine-type endopeptidase activity +
                                                                        is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of serine-type endopeptidase activity
                                                                is-anegative regulation of peptidase activity in other organism +
                                                                is-anegative regulation of serine-type peptidase activity +
                                                                is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of molecular function
                                is-aregulation of catalytic activity
                                        is-aregulation of hydrolase activity
                                                is-anegative regulation of hydrolase activity
                                                        is-anegative regulation of peptidase activity
                                                                is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                        is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of cysteine-type endopeptidase activity +
                                                                        is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of serine-type endopeptidase activity
                                                                is-anegative regulation of peptidase activity in other organism +
                                                                is-anegative regulation of serine-type peptidase activity +
                                                                is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of molecular function
                                is-aregulation of catalytic activity
                                        is-aregulation of hydrolase activity
                                                is-aregulation of peptidase activity
                                                        is-anegative regulation of peptidase activity
                                                                is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                        is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of cysteine-type endopeptidase activity +
                                                                        is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of serine-type endopeptidase activity
                                                                is-anegative regulation of peptidase activity in other organism +
                                                                is-anegative regulation of serine-type peptidase activity +
                                                                is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of molecular function
                                is-aregulation of catalytic activity
                                        is-aregulation of hydrolase activity
                                                is-aregulation of peptidase activity
                                                        is-aregulation of endopeptidase activity
                                                                is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                        is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of cysteine-type endopeptidase activity +
                                                                        is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of serine-type endopeptidase activity
                                                                is-apositive regulation of endopeptidase activity +
                                                                is-aregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                is-aregulation of cysteine-type endopeptidase activity +
                                                                is-aregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                is-aregulation of serine-type endopeptidase activity +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                is-aproteolysis
                                                        regulatesregulation of proteolysis
                                                                is-aregulation of peptidase activity
                                                                        is-anegative regulation of peptidase activity
                                                                                is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                        is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                        is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                        is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                        is-anegative regulation of serine-type endopeptidase activity
                                                                                is-anegative regulation of peptidase activity in other organism +
                                                                                is-anegative regulation of serine-type peptidase activity +
                                                                                is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                is-aproteolysis
                                                        regulatesregulation of proteolysis
                                                                is-aregulation of peptidase activity
                                                                        is-aregulation of endopeptidase activity
                                                                                is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                        is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                        is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                        is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                        is-anegative regulation of serine-type endopeptidase activity
                                                                                is-apositive regulation of endopeptidase activity +
                                                                                is-aregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                                is-aregulation of cysteine-type endopeptidase activity +
                                                                                is-aregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                                is-aregulation of serine-type endopeptidase activity +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                regulatesregulation of protein metabolic process
                                                        is-aregulation of proteolysis
                                                                is-aregulation of peptidase activity
                                                                        is-anegative regulation of peptidase activity
                                                                                is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                        is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                        is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                        is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                        is-anegative regulation of serine-type endopeptidase activity
                                                                                is-anegative regulation of peptidase activity in other organism +
                                                                                is-anegative regulation of serine-type peptidase activity +
                                                                                is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                regulatesregulation of protein metabolic process
                                                        is-aregulation of proteolysis
                                                                is-aregulation of peptidase activity
                                                                        is-aregulation of endopeptidase activity
                                                                                is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                        is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                        is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                        is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                        is-anegative regulation of serine-type endopeptidase activity
                                                                                is-apositive regulation of endopeptidase activity +
                                                                                is-aregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                                is-aregulation of cysteine-type endopeptidase activity +
                                                                                is-aregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                                is-aregulation of serine-type endopeptidase activity +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        regulatesregulation of macromolecule metabolic process
                                                is-aregulation of protein metabolic process
                                                        is-aregulation of proteolysis
                                                                is-aregulation of peptidase activity
                                                                        is-anegative regulation of peptidase activity
                                                                                is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                        is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                        is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                        is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                        is-anegative regulation of serine-type endopeptidase activity
                                                                                is-anegative regulation of peptidase activity in other organism +
                                                                                is-anegative regulation of serine-type peptidase activity +
                                                                                is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        regulatesregulation of macromolecule metabolic process
                                                is-aregulation of protein metabolic process
                                                        is-aregulation of proteolysis
                                                                is-aregulation of peptidase activity
                                                                        is-aregulation of endopeptidase activity
                                                                                is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                        is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                        is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                        is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                        is-anegative regulation of serine-type endopeptidase activity
                                                                                is-apositive regulation of endopeptidase activity +
                                                                                is-aregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                                is-aregulation of cysteine-type endopeptidase activity +
                                                                                is-aregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                                is-aregulation of serine-type endopeptidase activity +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-aprotein metabolic process
                                        is-aproteolysis
                                                regulatesregulation of proteolysis
                                                        is-aregulation of peptidase activity
                                                                is-anegative regulation of peptidase activity
                                                                        is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of serine-type endopeptidase activity
                                                                        is-anegative regulation of peptidase activity in other organism +
                                                                        is-anegative regulation of serine-type peptidase activity +
                                                                        is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-aprotein metabolic process
                                        is-aproteolysis
                                                regulatesregulation of proteolysis
                                                        is-aregulation of peptidase activity
                                                                is-aregulation of endopeptidase activity
                                                                        is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of serine-type endopeptidase activity
                                                                        is-apositive regulation of endopeptidase activity +
                                                                        is-aregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                        is-aregulation of cysteine-type endopeptidase activity +
                                                                        is-aregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                        is-aregulation of serine-type endopeptidase activity +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-aprotein metabolic process
                                        regulatesregulation of protein metabolic process
                                                is-aregulation of proteolysis
                                                        is-aregulation of peptidase activity
                                                                is-anegative regulation of peptidase activity
                                                                        is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of serine-type endopeptidase activity
                                                                        is-anegative regulation of peptidase activity in other organism +
                                                                        is-anegative regulation of serine-type peptidase activity +
                                                                        is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-aprotein metabolic process
                                        regulatesregulation of protein metabolic process
                                                is-aregulation of proteolysis
                                                        is-aregulation of peptidase activity
                                                                is-aregulation of endopeptidase activity
                                                                        is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of serine-type endopeptidase activity
                                                                        is-apositive regulation of endopeptidase activity +
                                                                        is-aregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                        is-aregulation of cysteine-type endopeptidase activity +
                                                                        is-aregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                        is-aregulation of serine-type endopeptidase activity +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                regulatesregulation of primary metabolic process
                                        is-aregulation of protein metabolic process
                                                is-aregulation of proteolysis
                                                        is-aregulation of peptidase activity
                                                                is-anegative regulation of peptidase activity
                                                                        is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of serine-type endopeptidase activity
                                                                        is-anegative regulation of peptidase activity in other organism +
                                                                        is-anegative regulation of serine-type peptidase activity +
                                                                        is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                regulatesregulation of primary metabolic process
                                        is-aregulation of protein metabolic process
                                                is-aregulation of proteolysis
                                                        is-aregulation of peptidase activity
                                                                is-aregulation of endopeptidase activity
                                                                        is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of serine-type endopeptidase activity
                                                                        is-apositive regulation of endopeptidase activity +
                                                                        is-aregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                        is-aregulation of cysteine-type endopeptidase activity +
                                                                        is-aregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                        is-aregulation of serine-type endopeptidase activity +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        regulatesregulation of metabolic process
                                is-aregulation of catalytic activity
                                        is-anegative regulation of catalytic activity
                                                is-anegative regulation of hydrolase activity
                                                        is-anegative regulation of peptidase activity
                                                                is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                        is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of cysteine-type endopeptidase activity +
                                                                        is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of serine-type endopeptidase activity
                                                                is-anegative regulation of peptidase activity in other organism +
                                                                is-anegative regulation of serine-type peptidase activity +
                                                                is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        regulatesregulation of metabolic process
                                is-aregulation of catalytic activity
                                        is-aregulation of hydrolase activity
                                                is-anegative regulation of hydrolase activity
                                                        is-anegative regulation of peptidase activity
                                                                is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                        is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of cysteine-type endopeptidase activity +
                                                                        is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of serine-type endopeptidase activity
                                                                is-anegative regulation of peptidase activity in other organism +
                                                                is-anegative regulation of serine-type peptidase activity +
                                                                is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        regulatesregulation of metabolic process
                                is-aregulation of catalytic activity
                                        is-aregulation of hydrolase activity
                                                is-aregulation of peptidase activity
                                                        is-anegative regulation of peptidase activity
                                                                is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                        is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of cysteine-type endopeptidase activity +
                                                                        is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of serine-type endopeptidase activity
                                                                is-anegative regulation of peptidase activity in other organism +
                                                                is-anegative regulation of serine-type peptidase activity +
                                                                is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        regulatesregulation of metabolic process
                                is-aregulation of catalytic activity
                                        is-aregulation of hydrolase activity
                                                is-aregulation of peptidase activity
                                                        is-aregulation of endopeptidase activity
                                                                is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                        is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of cysteine-type endopeptidase activity +
                                                                        is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of serine-type endopeptidase activity
                                                                is-apositive regulation of endopeptidase activity +
                                                                is-aregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                is-aregulation of cysteine-type endopeptidase activity +
                                                                is-aregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                is-aregulation of serine-type endopeptidase activity +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        regulatesregulation of metabolic process
                                is-aregulation of macromolecule metabolic process
                                        is-aregulation of protein metabolic process
                                                is-aregulation of proteolysis
                                                        is-aregulation of peptidase activity
                                                                is-anegative regulation of peptidase activity
                                                                        is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of serine-type endopeptidase activity
                                                                        is-anegative regulation of peptidase activity in other organism +
                                                                        is-anegative regulation of serine-type peptidase activity +
                                                                        is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        regulatesregulation of metabolic process
                                is-aregulation of macromolecule metabolic process
                                        is-aregulation of protein metabolic process
                                                is-aregulation of proteolysis
                                                        is-aregulation of peptidase activity
                                                                is-aregulation of endopeptidase activity
                                                                        is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of serine-type endopeptidase activity
                                                                        is-apositive regulation of endopeptidase activity +
                                                                        is-aregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                        is-aregulation of cysteine-type endopeptidase activity +
                                                                        is-aregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                        is-aregulation of serine-type endopeptidase activity +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        regulatesregulation of metabolic process
                                is-aregulation of primary metabolic process
                                        is-aregulation of protein metabolic process
                                                is-aregulation of proteolysis
                                                        is-aregulation of peptidase activity
                                                                is-anegative regulation of peptidase activity
                                                                        is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of serine-type endopeptidase activity
                                                                        is-anegative regulation of peptidase activity in other organism +
                                                                        is-anegative regulation of serine-type peptidase activity +
                                                                        is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        regulatesregulation of metabolic process
                                is-aregulation of primary metabolic process
                                        is-aregulation of protein metabolic process
                                                is-aregulation of proteolysis
                                                        is-aregulation of peptidase activity
                                                                is-aregulation of endopeptidase activity
                                                                        is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of serine-type endopeptidase activity
                                                                        is-apositive regulation of endopeptidase activity +
                                                                        is-aregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                        is-aregulation of cysteine-type endopeptidase activity +
                                                                        is-aregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                        is-aregulation of serine-type endopeptidase activity +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of metabolic process
                                is-aregulation of catalytic activity
                                        is-anegative regulation of catalytic activity
                                                is-anegative regulation of hydrolase activity
                                                        is-anegative regulation of peptidase activity
                                                                is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                        is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of cysteine-type endopeptidase activity +
                                                                        is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of serine-type endopeptidase activity
                                                                is-anegative regulation of peptidase activity in other organism +
                                                                is-anegative regulation of serine-type peptidase activity +
                                                                is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of metabolic process
                                is-aregulation of catalytic activity
                                        is-aregulation of hydrolase activity
                                                is-anegative regulation of hydrolase activity
                                                        is-anegative regulation of peptidase activity
                                                                is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                        is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of cysteine-type endopeptidase activity +
                                                                        is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of serine-type endopeptidase activity
                                                                is-anegative regulation of peptidase activity in other organism +
                                                                is-anegative regulation of serine-type peptidase activity +
                                                                is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of metabolic process
                                is-aregulation of catalytic activity
                                        is-aregulation of hydrolase activity
                                                is-aregulation of peptidase activity
                                                        is-anegative regulation of peptidase activity
                                                                is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                        is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of cysteine-type endopeptidase activity +
                                                                        is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of serine-type endopeptidase activity
                                                                is-anegative regulation of peptidase activity in other organism +
                                                                is-anegative regulation of serine-type peptidase activity +
                                                                is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of metabolic process
                                is-aregulation of catalytic activity
                                        is-aregulation of hydrolase activity
                                                is-aregulation of peptidase activity
                                                        is-aregulation of endopeptidase activity
                                                                is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                        is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of cysteine-type endopeptidase activity +
                                                                        is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                        is-anegative regulation of serine-type endopeptidase activity
                                                                is-apositive regulation of endopeptidase activity +
                                                                is-aregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                is-aregulation of cysteine-type endopeptidase activity +
                                                                is-aregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                is-aregulation of serine-type endopeptidase activity +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of metabolic process
                                is-aregulation of macromolecule metabolic process
                                        is-aregulation of protein metabolic process
                                                is-aregulation of proteolysis
                                                        is-aregulation of peptidase activity
                                                                is-anegative regulation of peptidase activity
                                                                        is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of serine-type endopeptidase activity
                                                                        is-anegative regulation of peptidase activity in other organism +
                                                                        is-anegative regulation of serine-type peptidase activity +
                                                                        is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of metabolic process
                                is-aregulation of macromolecule metabolic process
                                        is-aregulation of protein metabolic process
                                                is-aregulation of proteolysis
                                                        is-aregulation of peptidase activity
                                                                is-aregulation of endopeptidase activity
                                                                        is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of serine-type endopeptidase activity
                                                                        is-apositive regulation of endopeptidase activity +
                                                                        is-aregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                        is-aregulation of cysteine-type endopeptidase activity +
                                                                        is-aregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                        is-aregulation of serine-type endopeptidase activity +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of metabolic process
                                is-aregulation of primary metabolic process
                                        is-aregulation of protein metabolic process
                                                is-aregulation of proteolysis
                                                        is-aregulation of peptidase activity
                                                                is-anegative regulation of peptidase activity
                                                                        is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of serine-type endopeptidase activity
                                                                        is-anegative regulation of peptidase activity in other organism +
                                                                        is-anegative regulation of serine-type peptidase activity +
                                                                        is-anegative regulation of ubiquitin-specific protease activity


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of metabolic process
                                is-aregulation of primary metabolic process
                                        is-aregulation of protein metabolic process
                                                is-aregulation of proteolysis
                                                        is-aregulation of peptidase activity
                                                                is-aregulation of endopeptidase activity
                                                                        is-anegative regulation of endopeptidase activity [GO:0010951] (177 genes, 204 annotations)
                                                                                is-anegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of cysteine-type endopeptidase activity +
                                                                                is-anegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
                                                                                is-anegative regulation of serine-type endopeptidase activity
                                                                        is-apositive regulation of endopeptidase activity +
                                                                        is-aregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                        is-aregulation of cysteine-type endopeptidase activity +
                                                                        is-aregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process +
                                                                        is-aregulation of serine-type endopeptidase activity +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/16/2014
MGI 5.19
The Jackson Laboratory