Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SELE
  • Mouse genes Sele
  • Rat genes Sele
  • Zfish genes sele
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sele

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070492	oligosaccharide binding	SELE	IDA		Human	PMID:7680663
Molecular Function	GO:0043274	phospholipase binding	SELE	IDA		Human	PMID:12960351
Molecular Function	GO:0005515	protein binding	SELE	IPI	UniProtKB:Q9NZ53	Human	PMID:18606703
Molecular Function	GO:0005515	protein binding	SELE	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SELE	IPI	UniProtKB:P54252	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SELE	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0033691	sialic acid binding	SELE	IDA		Human	PMID:7680663
Molecular Function	GO:0004888	transmembrane signaling receptor activity	SELE	IMP		Human	PMID:12960351
Cellular Component	GO:0005901	caveola	SELE	IDA		Human	PMID:12960351
Cellular Component	GO:0005905	clathrin-coated pit	SELE	IDA		Human	PMID:18029551
Cellular Component	GO:0030863	cortical cytoskeleton	SELE	IDA		Human	PMID:8609175
Cellular Component	GO:0005615	extracellular space	SELE	IDA		Human	PMID:9290466
Cellular Component	GO:0045121	membrane raft	SELE	IDA		Human	PMID:18029551
Cellular Component	GO:0048471	perinuclear region of cytoplasm	SELE	IDA		Human	PMID:12960351
Cellular Component	GO:0005886	plasma membrane	SELE	IDA		Human	PMID:28011641
Biological Process	GO:0030029	actin filament-based process	SELE	IDA		Human	PMID:8609175
Biological Process	GO:0007202	activation of phospholipase C activity	SELE	IMP		Human	PMID:12960351
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	SELE	IMP		Human	PMID:18029551
Biological Process	GO:0006954	inflammatory response	Sele	IMP		Rat	PMID:7527013|RGD:1580044
Biological Process	GO:0007159	leukocyte cell-cell adhesion	SELE	IDA		Human	PMID:7680663
Biological Process	GO:0050900	leukocyte migration	Sele	IGI	MGI:MGI:98280	Mouse	PMID:17114491
Biological Process	GO:0050900	leukocyte migration	Sele	IEP		Rat	PMID:7544926|RGD:1580045
Biological Process	GO:0050901	leukocyte tethering or rolling	SELE	IMP		Human	PMID:18029551
Biological Process	GO:0002687	positive regulation of leukocyte migration	Sele	IGI	MGI:MGI:98280	Mouse	PMID:17114491
Biological Process	GO:1903238	positive regulation of leukocyte tethering or rolling	Sele	IMP		Mouse	MGI:MGI:1860416|PMID:10894166
Biological Process	GO:0002092	positive regulation of receptor internalization	SELE	IDA		Human	PMID:9312078
Biological Process	GO:0034097	response to cytokine	Sele	IEP		Rat	PMID:19489247|RGD:2313598
Biological Process	GO:0070555	response to interleukin-1	SELE	IDA		Human	PMID:8609175

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern