Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes S100B
  • Mouse genes S100b
  • Rat genes S100b
  • Zfish genes s100b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set S100b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	S100B	IDA		Human	PMID:20950652
Molecular Function	GO:0005509	calcium ion binding	S100b	IDA		Rat	PMID:14621986|RGD:155888563
Molecular Function	GO:0005509	calcium ion binding	S100b	IDA		Rat	PMID:18949447|RGD:5508833
Molecular Function	GO:0048306	calcium-dependent protein binding	S100B	IDA		Human	PMID:10913138
Molecular Function	GO:0042802	identical protein binding	S100B	IPI	UniProtKB:P04271	Human	PMID:10913138
Molecular Function	GO:0042802	identical protein binding	S100B	IPI	UniProtKB:P04271	Human	PMID:17660747
Molecular Function	GO:0042802	identical protein binding	S100B	IPI	UniProtKB:P04271	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	S100B	IPI	UniProtKB:P04271	Human	PMID:26871637
Molecular Function	GO:0042802	identical protein binding	S100B	IPI	UniProtKB:P04271	Human	PMID:27107012
Molecular Function	GO:0042802	identical protein binding	S100B	IPI	UniProtKB:P04271	Human	PMID:32296183
Molecular Function	GO:0042802	identical protein binding	S100B	IPI	UniProtKB:P04271	Human	PMID:9519411
Molecular Function	GO:0042802	identical protein binding	S100b	IPI	RGD:3615	Rat	PMID:18949447|RGD:5508833
Molecular Function	GO:0043167	ion binding	S100B	EXP		Human	PMID:18384084
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P06703	Human	PMID:10913138
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P23297	Human	PMID:10913138
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P31949	Human	PMID:10913138
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P23297	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:Q15109	Human	PMID:17660747
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:Q15109	Human	PMID:17726019
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P04637	Human	PMID:20591429
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:Q00987	Human	PMID:20591429
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P23297	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P26447	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P23297	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P25815	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P26447	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P29034	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:Q9NZD8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P25815	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P26447	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P23297	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P29034	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:Q5T7Y6	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P06703	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P23297	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P10636	Human	PMID:3111527
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:Q9NZD8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:O15151	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P04637	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P35579	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P52907	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:Q15418	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P06702	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P23297	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P25815	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P26447	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P29034	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:Q8WXG8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:Q9NZD8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:A0A024RC47	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:O14576-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:O75553-5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P01023	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P0DMV8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P13051-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P17612	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P21860	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P23297	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P27824-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P41271-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P48730-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P62136	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:P63000	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:Q06481-5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:Q07954-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:Q13867	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:Q15843	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:Q86YQ8-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:Q92599-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:Q9UGL9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:Q9UQM7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100B	IPI	UniProtKB:Q9Y4K3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100b	IPI	UniProtKB:Q63495	Rat	PMID:19910580|RGD:2325647
Molecular Function	GO:0042803	protein homodimerization activity	S100B	IDA		Human	PMID:10913138
Molecular Function	GO:0042803	protein homodimerization activity	S100B	IPI	UniProtKB:P04271	Human	PMID:9519411
Molecular Function	GO:0050786	RAGE receptor binding	S100B	IPI	UniProtKB:Q15109	Human	PMID:15033494
Molecular Function	GO:0050786	RAGE receptor binding	S100b	IPI	RGD:69258	Rat	PMID:19910580|RGD:2325647
Molecular Function	GO:0044548	S100 protein binding	S100B	IPI	UniProtKB:P04271	Human	PMID:10913138
Molecular Function	GO:0044548	S100 protein binding	S100B	IPI	UniProtKB:P04271	Human	PMID:9519411
Molecular Function	GO:0005102	signaling receptor binding	S100b	IPI	RGD:2520	Rat	PMID:18445708|RGD:2311563
Molecular Function	GO:0008270	zinc ion binding	S100B	IDA		Human	PMID:20950652
Molecular Function	GO:0008270	zinc ion binding	S100b	IDA		Rat	PMID:14621986|RGD:155888563
Molecular Function	GO:0008270	zinc ion binding	S100b	IDA		Rat	PMID:15823027|RGD:5508851
Cellular Component	GO:0005737	cytoplasm	S100B	IDA		Human	PMID:10913138
Cellular Component	GO:0005737	cytoplasm	S100b	IDA		Mouse	PMID:24582971
Cellular Component	GO:0005737	cytoplasm	S100b	IDA		Mouse	PMID:25433207
Cellular Component	GO:0005737	cytoplasm	S100b	IDA		Rat	PMID:11180510|RGD:5509057
Cellular Component	GO:0005829	cytosol	S100B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005615	extracellular space	S100b	IDA		Rat	PMID:21098642|RGD:5508827
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	S100B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043025	neuronal cell body	S100b	IDA		Mouse	PMID:15248193
Cellular Component	GO:0005654	nucleoplasm	S100B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	S100B	IDA		Human	PMID:10913138
Cellular Component	GO:0005634	nucleus	S100b	IDA		Mouse	PMID:15782413
Cellular Component	GO:0048471	perinuclear region of cytoplasm	S100B	IDA		Human	PMID:12118070
Cellular Component	GO:0048471	perinuclear region of cytoplasm	S100B	IDA		Human	PMID:15033494
Cellular Component	GO:0001726	ruffle	S100B	IDA		Human	PMID:10913138
Biological Process	GO:0048708	astrocyte differentiation	S100b	IEP		Rat	PMID:19147496|RGD:5508832
Biological Process	GO:0071456	cellular response to hypoxia	S100b	IEP		Rat	PMID:19910580|RGD:2325647
Biological Process	GO:0007611	learning or memory	S100b	IMP		Mouse	MGI:MGI:2450006|PMID:11891290
Biological Process	GO:0060291	long-term synaptic potentiation	S100b	IEP		Rat	PMID:21546003|RGD:5508826
Biological Process	GO:0007613	memory	S100b	IMP	MGI:MGI:2451049	Mouse	PMID:11891290
Biological Process	GO:2001015	negative regulation of skeletal muscle cell differentiation	S100b	IMP		Rat	PMID:20069545|RGD:5508829
Biological Process	GO:1990138	neuron projection extension	S100b	IDA		Mouse	MGI:MGI:7434528|PMID:2592414
Biological Process	GO:0043065	positive regulation of apoptotic process	S100b	IMP		Rat	PMID:17639288|RGD:5508839
Biological Process	GO:0008284	positive regulation of cell population proliferation	S100b	IMP		Rat	PMID:2229184|RGD:5509056
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	S100B	IDA		Human	PMID:15033494
Biological Process	GO:0031643	positive regulation of myelination	S100b	IMP		Rat	PMID:25536222|RGD:12879826
Biological Process	GO:0045666	positive regulation of neuron differentiation	S100b	IDA		Mouse	MGI:MGI:66943|PMID:8202493
Biological Process	GO:0045666	positive regulation of neuron differentiation	S100b	IDA		Mouse	MGI:MGI:7434528|PMID:2592414
Biological Process	GO:0050806	positive regulation of synaptic transmission	S100b	IMP		Rat	PMID:12428274|RGD:5509054
Biological Process	GO:0008360	regulation of cell shape	S100b	IMP		Rat	PMID:2229184|RGD:5509056
Biological Process	GO:0048168	regulation of neuronal synaptic plasticity	S100b	IMP	MGI:MGI:2451049	Mouse	PMID:11891290
Biological Process	GO:0051384	response to glucocorticoid	S100b	IEP		Rat	PMID:16112204|RGD:5508849
Biological Process	GO:0051597	response to methylmercury	S100b	IEP		Rat	PMID:21783483|RGD:5508852

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern