Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAB8A
  • Mouse genes Rab8a
  • Rat genes Rab8a
  • Zfish genes rab8a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rab8a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019003	GDP binding	RAB8A	IDA		Human	PMID:20937701
Molecular Function	GO:0005525	GTP binding	RAB8A	IDA		Human	PMID:20937701
Molecular Function	GO:0003924	GTPase activity	RAB8A	IDA		Human	PMID:17646400
Molecular Function	GO:0031489	myosin V binding	RAB8A	IPI	UniProtKB:Q9Y4I1	Human	PMID:24006491
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:P37840	Human	PMID:15207266
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q96CV9	Human	PMID:15837803
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:P47224	Human	PMID:16541104
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q01968	Human	PMID:16902405
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q5BJF6-3	Human	PMID:17646400
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q96CV9	Human	PMID:17646400
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q9Y2I9	Human	PMID:17646400
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q9NR09	Human	PMID:18329369
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q8N3F8	Human	PMID:19864458
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q9H4M9	Human	PMID:19864458
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q96QF0-2	Human	PMID:20308558
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q96CV9	Human	PMID:20388642
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q8TCI5	Human	PMID:20643351
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q9D9W1	Human	PMID:20643351
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q96QF0	Human	PMID:21273506
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q01968	Human	PMID:21378754
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q5ZWZ3	Human	PMID:22011575
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:M0R2J8	Human	PMID:22159412
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q01968	Human	PMID:22543976
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q96CV9	Human	PMID:22854040
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q96QF0-2	Human	PMID:26258637
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:P47224	Human	PMID:26824392
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q01968	Human	PMID:26824392
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q5S007	Human	PMID:26824392
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q96QF0	Human	PMID:26824392
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q13501	Human	PMID:27103069
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q96QF0	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:O60271	Human	PMID:29125462
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:P47224	Human	PMID:29125462
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q01968	Human	PMID:29125462
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q5EBL4	Human	PMID:29125462
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q969X0	Human	PMID:29125462
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:O60271	Human	PMID:32017888
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q5S007	Human	PMID:32017888
Molecular Function	GO:0005515	protein binding	RAB8A	IPI	UniProtKB:Q969X0	Human	PMID:32017888
Molecular Function	GO:0005515	protein binding	Rab8a	IPI	UniProtKB:P50395|UniProtKB:Q8BMD2	Mouse	MGI:MGI:5644575|PMID:25860027
Molecular Function	GO:0005515	protein binding	Rab8a	IPI	UniProtKB:P47708	Mouse	MGI:MGI:4839453|PMID:14722103
Molecular Function	GO:0005515	protein binding	Rab8a	IPI	UniProtKB:Q3TN34	Mouse	MGI:MGI:5508599|PMID:18094055
Molecular Function	GO:0005515	protein binding	Rab8a	IPI	UniProtKB:P47708	Mouse	MGI:MGI:2176311|PMID:11773082
Molecular Function	GO:0005515	protein binding	Rab8a	IPI	UniProtKB:O55042	Mouse	MGI:MGI:5605417|PMID:24983211
Molecular Function	GO:0005515	protein binding	Rab8a	IPI	UniProtKB:P47708|UniProtKB:Q9R0Q1	Mouse	MGI:MGI:2176311|PMID:11773082
Molecular Function	GO:0005515	protein binding	Rab8a	IPI	UniProtKB:P08F94	Mouse	MGI:MGI:6467684|PMID:20048263
Molecular Function	GO:0005515	protein binding	Rab8a	IPI	UniProtKB:Q8BGT6|UniProtKB:Q8VDP3	Mouse	MGI:MGI:5508599|PMID:18094055
Molecular Function	GO:0005515	protein binding	Rab8a	IPI	PR:Q9EQZ7	Mouse	PMID:12578829
Molecular Function	GO:0005515	protein binding	Rab8a	IPI	PR:Q768S4	Mouse	PMID:12578829
Molecular Function	GO:0019901	protein kinase binding	Rab8a	IPI	RGD:1306273	Rat	PMID:12700184|RGD:2291909
Molecular Function	GO:1990782	protein tyrosine kinase binding	Rab8a	IPI	RGD:1306273	Rat	PMID:12700184|RGD:2291909
Cellular Component	GO:0005813	centrosome	RAB8A	IDA		Human	PMID:24421332
Cellular Component	GO:0005813	centrosome	RAB8A	IDA		Human	PMID:25849865
Cellular Component	GO:0036064	ciliary basal body	Rab8a	IDA		Mouse	MGI:MGI:5644575|PMID:25860027
Cellular Component	GO:0036064	ciliary basal body	Rab8a	IDA		Mouse	PMID:19625297
Cellular Component	GO:0097546	ciliary base	Rab8a	IDA		Mouse	PMID:24947469
Cellular Component	GO:0060170	ciliary membrane	Rab8a	IDA		Mouse	PMID:29038301
Cellular Component	GO:0005929	cilium	RAB8A	IDA		Human	PMID:21844891
Cellular Component	GO:0005929	cilium	RAB8A	IDA		Human	PMID:17646400
Cellular Component	GO:0005929	cilium	RAB8A	IDA		Human	PMID:24421332
Cellular Component	GO:0005929	cilium	Rab8a	IMP		Mouse	MGI:MGI:6467684|PMID:20048263
Cellular Component	GO:0005929	cilium	Rab8a	IDA		Mouse	MGI:MGI:5644575|PMID:25860027
Cellular Component	GO:0005929	cilium	Rab8a	IDA		Mouse	PMID:24469809
Cellular Component	GO:0031410	cytoplasmic vesicle	Rab8a	IDA		Rat	PMID:15837803|RGD:8554668
Cellular Component	GO:0030425	dendrite	Rab8a	IDA		Rat	PMID:8408204|RGD:2306266
Cellular Component	GO:0043197	dendritic spine	Rab8a	IDA		Rat	PMID:15297461|RGD:2306456
Cellular Component	GO:0070062	extracellular exosome	RAB8A	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	RAB8A	HDA		Human	PMID:20458337
Cellular Component	GO:0098978	glutamatergic synapse	Rab8a	IDA		Rat	PMID:15297461|RGD:2306456
Cellular Component	GO:0098978	glutamatergic synapse	Rab8a	IMP		Rat	PMID:15297461|RGD:2306456
Cellular Component	GO:0098978	glutamatergic synapse	Rab8a	IDA		Rat	PMID:18045925|RGD:2306457
Cellular Component	GO:0098978	glutamatergic synapse	Rab8a	IMP		Rat	PMID:18045925|RGD:2306457
Cellular Component	GO:0005794	Golgi apparatus	Rab8a	IDA		Rat	PMID:15837803|RGD:8554668
Cellular Component	GO:0030496	midbody	RAB8A	IDA		Human	PMID:22159412
Cellular Component	GO:0043005	neuron projection	Rab8a	IDA		Mouse	PMID:20592197
Cellular Component	GO:0043025	neuronal cell body	Rab8a	IDA		Rat	PMID:8408204|RGD:2306266
Cellular Component	GO:0097730	non-motile cilium	RAB8A	IDA		Human	PMID:17574030
Cellular Component	GO:0097730	non-motile cilium	RAB8A	IDA		Human	PMID:24648492
Cellular Component	GO:0097730	non-motile cilium	Rab8a	IDA		Mouse	PMID:19625297
Cellular Component	GO:0097730	non-motile cilium	Rab8a	IDA		Mouse	PMID:20592197
Cellular Component	GO:0045335	phagocytic vesicle	RAB8A	IDA		Human	PMID:21255211
Cellular Component	GO:0005886	plasma membrane	Rab8a	IDA		Mouse	MGI:MGI:5508599|PMID:18094055
Cellular Component	GO:0005886	plasma membrane	Rab8a	IDA		Rat	PMID:8366094|RGD:2306265
Cellular Component	GO:0014069	postsynaptic density	Rab8a	IDA		Rat	PMID:15297461|RGD:2306456
Cellular Component	GO:0055037	recycling endosome	Rab8a	IDA		Mouse	MGI:MGI:5508599|PMID:18094055
Cellular Component	GO:0055037	recycling endosome	Rab8a	IDA		Mouse	PMID:19061864
Cellular Component	GO:0055038	recycling endosome membrane	RAB8A	IDA		Human	PMID:19864458
Cellular Component	GO:0055038	recycling endosome membrane	RAB8A	IDA		Human	PMID:21951725
Cellular Component	GO:0045202	synapse	Rab8a	EXP		Rat	PMID:24876496|RGD:10047219
Cellular Component	GO:0045202	synapse	Rab8a	IDA		Rat	PMID:24876496|RGD:10047219
Cellular Component	GO:0030140	trans-Golgi network transport vesicle	Rab8a	IDA		Mouse	PMID:17765678
Biological Process	GO:0007409	axonogenesis	Rab8a	IMP		Rat	PMID:21856246|RGD:8553614
Biological Process	GO:0032869	cellular response to insulin stimulus	Rab8a	IMP		Rat	PMID:21041651|RGD:8554419
Biological Process	GO:0060271	cilium assembly	RAB8A	IDA		Human	PMID:17574030
Biological Process	GO:0060271	cilium assembly	RAB8A	IMP		Human	PMID:17646400
Biological Process	GO:0060271	cilium assembly	RAB8A	IMP		Human	PMID:21844891
Biological Process	GO:0060271	cilium assembly	Rab8a	IMP		Mouse	MGI:MGI:5644575|PMID:25860027
Biological Process	GO:0007030	Golgi organization	RAB8A	IMP		Human	PMID:26209634
Biological Process	GO:0048210	Golgi vesicle fusion to target membrane	RAB8A	IDA		Human	PMID:17574030
Biological Process	GO:0032402	melanosome transport	rab8a	IMP		Zfish	PMID:17574030|ZFIN:ZDB-PUB-070629-10
Biological Process	GO:0098969	neurotransmitter receptor transport to postsynaptic membrane	Rab8a	IDA		Rat	PMID:15297461|RGD:2306456
Biological Process	GO:0098969	neurotransmitter receptor transport to postsynaptic membrane	Rab8a	IMP		Rat	PMID:15297461|RGD:2306456
Biological Process	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane	Rab8a	IDA		Rat	PMID:18045925|RGD:2306457
Biological Process	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane	Rab8a	IMP		Rat	PMID:18045925|RGD:2306457
Biological Process	GO:0035845	photoreceptor cell outer segment organization	rab8a	IGI	ZFIN:ZDB-GENO-100507-9,ZFIN:ZDB-MRPHLNO-080724-5	Zfish	PMID:21816947
Biological Process	GO:0035845	photoreceptor cell outer segment organization	rab8a	IMP	ZFIN:ZDB-MRPHLNO-080724-5	Zfish	PMID:21816947
Biological Process	GO:0061512	protein localization to cilium	Rab8a	IMP		Mouse	MGI:MGI:5644575|PMID:25860027
Biological Process	GO:0072659	protein localization to plasma membrane	Rab8a	IDA		Rat	PMID:21041651|RGD:8554419
Biological Process	GO:0010506	regulation of autophagy	RAB8A	IMP		Human	PMID:27103069
Biological Process	GO:0048169	regulation of long-term neuronal synaptic plasticity	Rab8a	IDA		Rat	PMID:15297461|RGD:2306456
Biological Process	GO:0048169	regulation of long-term neuronal synaptic plasticity	Rab8a	IMP		Rat	PMID:18045925|RGD:2306457
Biological Process	GO:0032880	regulation of protein localization	Rab8a	IMP		Rat	PMID:18701652|RGD:2306295
Biological Process	GO:0051223	regulation of protein transport	Rab8a	IDA		Rat	PMID:15297461|RGD:2306456
Biological Process	GO:0051223	regulation of protein transport	Rab8a	IMP		Rat	PMID:18045925|RGD:2306457
Biological Process	GO:0051223	regulation of protein transport	Rab8a	IMP		Rat	PMID:8408204|RGD:2306266
Biological Process	GO:0006904	vesicle docking involved in exocytosis	RAB8A	IDA		Human	PMID:17574030
Biological Process	GO:0099003	vesicle-mediated transport in synapse	Rab8a	IDA		Rat	PMID:15297461|RGD:2306456
Biological Process	GO:0099003	vesicle-mediated transport in synapse	Rab8a	IMP		Rat	PMID:15297461|RGD:2306456
Biological Process	GO:0099003	vesicle-mediated transport in synapse	Rab8a	IDA		Rat	PMID:18045925|RGD:2306457
Biological Process	GO:0099003	vesicle-mediated transport in synapse	Rab8a	IMP		Rat	PMID:18045925|RGD:2306457

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern