Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Pard3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes PARD3
- Mouse genes Pard3
- Rat genes Pard3
- Zfish genes pard3aa,pard3ab
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pard3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Pard3	IPI	UniProtKB:Q9Z340	Rat	PMID:23643951\|RGD:13432244
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	Pard3	IDA		Rat	PMID:18082612\|RGD:8553352
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	Pard3	IDA		Rat	PMID:18082612\|RGD:8553352
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	Pard3	IDA		Rat	PMID:18082612\|RGD:8553352
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:Q9JK83	Human	PMID:10934474
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:Q9NPB6	Human	PMID:11257119
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:P41743	Human	PMID:14676191
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:P63104	Human	PMID:14676191
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:Q04917	Human	PMID:14676191
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:Q8ND90	Human	PMID:14676191
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:Q9BYG4	Human	PMID:14676191
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:Q9BYG5	Human	PMID:14676191
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:Q9NPB6	Human	PMID:14676191
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:P63104	Human	PMID:15161933
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:Q9H8V3	Human	PMID:15254234
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:P33151	Human	PMID:17057644
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:Q9NPB6	Human	PMID:17057644
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:Q9Y624	Human	PMID:17057644
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:Q04917	Human	PMID:17979178
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:Q8TES7	Human	PMID:18838552
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:Q6ZPF3	Human	PMID:19893486
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:Q62074	Human	PMID:22579248
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:P04637	Human	PMID:22653443
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:Q9BYG5	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:Q9JK83	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:Q9NPB6	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:Q86UD0	Human	PMID:26766442
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:P63104	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:Q04917	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PARD3	IPI	UniProtKB:P41743	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	Pard3	IPI	UniProtKB:Q9Z101	Mouse	MGI:MGI:3687818\|PMID:10954424
Molecular Function	GO:0005515	protein binding	Pard3	IPI	UniProtKB:Q8R1S4	Mouse	MGI:MGI:5474897\|PMID:23446420
Molecular Function	GO:0005515	protein binding	Pard3	IPI	UniProtKB:P35917\|UniProtKB:P98078	Mouse	MGI:MGI:5476876\|PMID:23354168
Molecular Function	GO:0005515	protein binding	Pard3	IPI	UniProtKB:Q8IXJ6	Mouse	MGI:MGI:5295137\|PMID:21949390
Molecular Function	GO:0005515	protein binding	Pard3	IPI	PR:Q9D8B7	Mouse	PMID:18055550
Molecular Function	GO:0005515	protein binding	Pard3	IPI	PR:Q8R5M8	Mouse	PMID:18055550
Molecular Function	GO:0005515	protein binding	Pard3	IPI	PR:Q6PDL0	Mouse	PMID:19540120
Molecular Function	GO:0005515	protein binding	Pard3	IPI	PR:Q8BIE6	Mouse	PMID:20080746
Molecular Function	GO:0005515	protein binding	Pard3	IPI	RGD:1307455	Rat	PMID:16474385\|RGD:10043325
Molecular Function	GO:0019903	protein phosphatase binding	Pard3	IPI	UniProtKB:O54857	Rat	PMID:18082612\|RGD:8553352
Molecular Function	GO:0019903	protein phosphatase binding	Pard3	IPI	UniProtKB:O54857	Rat	PMID:18550519\|RGD:8554471
Cellular Component	GO:0005912	adherens junction	Pard3	IDA		Mouse	PMID:20080746
Cellular Component	GO:0005912	adherens junction	Pard3	IDA		Mouse	PMID:12203721
Cellular Component	GO:0005912	adherens junction	Pard3	IDA		Mouse	PMID:12515806
Cellular Component	GO:0043296	apical junction complex	Pard3	IDA		Mouse	PMID:22512338
Cellular Component	GO:0045177	apical part of cell	Pard3	IDA		Mouse	PMID:21385765
Cellular Component	GO:0016324	apical plasma membrane	pard3ab	IDA		Zfish	PMID:12835393
Cellular Component	GO:0016324	apical plasma membrane	pard3ab	IDA		Zfish	PMID:18817769
Cellular Component	GO:0044295	axonal growth cone	Pard3	IDA		Rat	PMID:15090620\|RGD:5131992
Cellular Component	GO:0005923	bicellular tight junction	PARD3	IDA		Human	PMID:14676191
Cellular Component	GO:0005923	bicellular tight junction	PARD3	IDA		Human	PMID:22006950
Cellular Component	GO:0005923	bicellular tight junction	Pard3	IDA		Mouse	MGI:MGI:3687818\|PMID:10954424
Cellular Component	GO:0030054	cell junction	PARD3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030054	cell junction	Pard3	IDA		Mouse	PMID:19540120
Cellular Component	GO:0005911	cell-cell junction	PARD3	IDA		Human	PMID:20332120
Cellular Component	GO:0005911	cell-cell junction	Pard3	IDA		Mouse	PMID:15775979
Cellular Component	GO:0005911	cell-cell junction	Pard3	IDA		Rat	PMID:18082612\|RGD:8553352
Cellular Component	GO:0005911	cell-cell junction	Pard3	IDA		Rat	PMID:18550519\|RGD:8554471
Cellular Component	GO:0005911	cell-cell junction	pard3ab	IDA		Zfish	PMID:28790366
Cellular Component	GO:0005737	cytoplasm	Pard3	IDA		Mouse	PMID:15766746
Cellular Component	GO:0005737	cytoplasm	pard3ab	IDA		Zfish	PMID:18817769
Cellular Component	GO:0033269	internode region of axon	Pard3	IDA		Mouse	MGI:MGI:5295137\|PMID:21949390
Cellular Component	GO:0043219	lateral loop	Pard3	IDA		Mouse	MGI:MGI:4441217\|PMID:20237282
Cellular Component	GO:0043025	neuronal cell body	Pard3	IDA		Rat	PMID:15090620\|RGD:5131992
Cellular Component	GO:0120157	PAR polarity complex	PARD3	IPI		Human	PMID:11257119
Cellular Component	GO:0005886	plasma membrane	PARD3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0032991	protein-containing complex	Pard3	IDA		Rat	PMID:18621709\|RGD:5131983
Cellular Component	GO:0043220	Schmidt-Lanterman incisure	Pard3	IDA		Mouse	MGI:MGI:4441217\|PMID:20237282
Cellular Component	GO:0005819	spindle	Pard3	IDA		Mouse	PMID:15766746
Biological Process	GO:0030036	actin cytoskeleton organization	pard3ab	IMP	ZFIN:ZDB-MRPHLNO-070717-1	Zfish	PMID:28790366
Biological Process	GO:0030036	actin cytoskeleton organization	pard3ab	IMP	ZFIN:ZDB-MRPHLNO-070717-3	Zfish	PMID:28790366
Biological Process	GO:0003383	apical constriction	Pard3	IGI	MGI:MGI:2442579	Mouse	PMID:21685893
Biological Process	GO:0003383	apical constriction	Pard3	IGI	MGI:MGI:107927	Mouse	PMID:21685893
Biological Process	GO:0070830	bicellular tight junction assembly	Pard3	IMP		Rat	PMID:18082612\|RGD:8553352
Biological Process	GO:0072554	blood vessel lumenization	pard3ab	IMP	ZFIN:ZDB-MRPHLNO-070717-1	Zfish	PMID:28790366
Biological Process	GO:0043010	camera-type eye development	pard3ab	IMP		Zfish	PMID:15081374
Biological Process	GO:0021535	cell migration in hindbrain	pard3ab	IMP	ZFIN:ZDB-MRPHLNO-070717-1	Zfish	PMID:17392791
Biological Process	GO:0022010	central nervous system myelination	pard3ab	IMP	ZFIN:ZDB-MRPHLNO-120127-4	Zfish	PMID:22128191
Biological Process	GO:0022010	central nervous system myelination	pard3ab	IMP	ZFIN:ZDB-MRPHLNO-070717-1	Zfish	PMID:22128191
Biological Process	GO:0051642	centrosome localization	Pard3	IMP		Mouse	PMID:19540120
Biological Process	GO:0060242	contact inhibition	pard3ab	IMP	ZFIN:ZDB-GENO-150326-6	Zfish	PMID:25130183
Biological Process	GO:0035907	dorsal aorta development	pard3ab	IMP	ZFIN:ZDB-MRPHLNO-070717-1	Zfish	PMID:28790366
Biological Process	GO:0048048	embryonic eye morphogenesis	pard3ab	IMP		Zfish	PMID:15081374
Biological Process	GO:0048702	embryonic neurocranium morphogenesis	pard3ab	IGI	ZFIN:ZDB-CRISPR-221216-1,ZFIN:ZDB-CRISPR-221216-2	Zfish	PMID:35789100
Biological Process	GO:0048702	embryonic neurocranium morphogenesis	pard3aa	IGI	ZFIN:ZDB-CRISPR-221216-1,ZFIN:ZDB-CRISPR-221216-2	Zfish	PMID:35789100
Biological Process	GO:0051660	establishment of centrosome localization	pard3ab	IMP	ZFIN:ZDB-MRPHLNO-100526-4	Zfish	PMID:20138861
Biological Process	GO:0051660	establishment of centrosome localization	pard3ab	IMP	ZFIN:ZDB-MRPHLNO-070717-1	Zfish	PMID:20138861
Biological Process	GO:0090162	establishment of epithelial cell polarity	Pard3	IMP		Rat	PMID:18082612\|RGD:8553352
Biological Process	GO:0090162	establishment of epithelial cell polarity	Pard3	IMP		Rat	PMID:18550519\|RGD:8554471
Biological Process	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	PARD3	IDA		Human	PMID:11257119
Biological Process	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	pard3ab	IMP		Zfish	PMID:15081374
Biological Process	GO:0000226	microtubule cytoskeleton organization	Pard3	IMP		Mouse	PMID:19540120
Biological Process	GO:0022011	myelination in peripheral nervous system	Pard3	IMP		Mouse	MGI:MGI:5295137\|PMID:21949390
Biological Process	GO:0022011	myelination in peripheral nervous system	pard3ab	IMP	ZFIN:ZDB-MRPHLNO-120127-4	Zfish	PMID:22128191
Biological Process	GO:0022011	myelination in peripheral nervous system	pard3ab	IMP	ZFIN:ZDB-MRPHLNO-070717-1	Zfish	PMID:22128191
Biological Process	GO:0010801	negative regulation of peptidyl-threonine phosphorylation	Pard3	IMP		Mouse	MGI:MGI:5295137\|PMID:21949390
Biological Process	GO:0001755	neural crest cell migration	pard3ab	IMP	ZFIN:ZDB-MRPHLNO-070717-1	Zfish	PMID:24173803
Biological Process	GO:0007405	neuroblast proliferation	pard3ab	IMP	ZFIN:ZDB-MRPHLNO-070717-1	Zfish	PMID:20453852
Biological Process	GO:0035845	photoreceptor cell outer segment organization	pard3ab	IMP	ZFIN:ZDB-MRPHLNO-070717-1	Zfish	PMID:25144710
Biological Process	GO:0031643	positive regulation of myelination	Pard3	IMP		Mouse	MGI:MGI:5295137\|PMID:21949390
Biological Process	GO:0002092	positive regulation of receptor internalization	Pard3	IMP		Mouse	MGI:MGI:5476876\|PMID:23354168
Biological Process	GO:1902414	protein localization to cell junction	pard3ab	IMP	ZFIN:ZDB-MRPHLNO-070717-1	Zfish	PMID:28790366
Biological Process	GO:0006612	protein targeting to membrane	Pard3	IDA		Rat	PMID:18550519\|RGD:8554471
Biological Process	GO:0032970	regulation of actin filament-based process	Pard3	IGI	MGI:MGI:107927	Mouse	PMID:21685893
Biological Process	GO:0032970	regulation of actin filament-based process	Pard3	IGI	MGI:MGI:2442579	Mouse	PMID:21685893
Biological Process	GO:0008360	regulation of cell shape	pard3ab	IMP	ZFIN:ZDB-MRPHLNO-070717-1	Zfish	PMID:28790366
Biological Process	GO:0008360	regulation of cell shape	pard3ab	IMP	ZFIN:ZDB-MRPHLNO-070717-3	Zfish	PMID:28790366
Biological Process	GO:0060341	regulation of cellular localization	Pard3	IMP		Rat	PMID:18621709\|RGD:5131983
Biological Process	GO:0048696	regulation of collateral sprouting in absence of injury	pard3ab	IGI	ZFIN:ZDB-MRPHLNO-140703-4,ZFIN:ZDB-MRPHLNO-140703-5	Zfish	PMID:24218155
Biological Process	GO:0048696	regulation of collateral sprouting in absence of injury	pard3ab	IMP	ZFIN:ZDB-MRPHLNO-140703-4	Zfish	PMID:24218155
Biological Process	GO:0044319	wound healing, spreading of cells	Pard3	IMP		Mouse	PMID:19540120

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.