| GO term: | apical junction complex |
| Synonym: | apical cell junction complex |
| Synonym: | apical junction |
| GO id: | GO:0043296 |
| Definition: | A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability. |
| Number of paths to term: | 1 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
cellular_componentcell junctioncell-cell junctionapical junction complex [GO:0043296] (120 genes, 144 annotations)septate junction +subapical complextight junction +zonula adherens +cell-cell adherens junction +cell-cell contact zone +desmosomefiltration diaphragm +gap junction +intercellular canaliculusoccluding junction +paranodal junctionplasmodesma +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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