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Term Detail
GO term:apical junction complex
Synonym: apical cell junction complex
Synonym: apical junction
GO id:GO:0043296
Definition:A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship

                is-acell junction
                        is-acell-cell junction
                                is-aapical junction complex [GO:0043296] (129 genes, 164 annotations)
                                        part-ofbicellular tight junction +
                                        part-ofseptate junction +
                                        part-ofsubapical complex
                                        part-ofzonula adherens +
                                is-acell-cell adherens junction +
                                is-acell-cell contact zone +
                                is-adesmosome +
                                is-afiltration diaphragm +
                                is-agap junction +
                                is-aintercellular canaliculus
                                is-aoccluding junction +
                                is-aparanodal junction
                                is-aplasmodesma +

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.08
The Jackson Laboratory