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Gene Ontology Browser
Term Detail
GO term:apical junction complex
Synonym: apical cell junction complex
Synonym: apical junction
GO id:GO:0043296
Definition:A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-acellular_component
                is-acell junction
                        is-acell-cell junction
                                is-aapical junction complex [GO:0043296] (123 genes, 154 annotations)
                                        part-ofseptate junction +
                                        part-ofsubapical complex
                                        part-oftight junction +
                                        part-ofzonula adherens +
                                is-acell-cell adherens junction +
                                is-acell-cell contact zone +
                                is-adesmosome
                                is-afiltration diaphragm +
                                is-agap junction +
                                is-aintercellular canaliculus
                                is-aoccluding junction +
                                is-aparanodal junction
                                is-aplasmodesma +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory