Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NHLRC1
  • Mouse genes Nhlrc1
  • Rat genes Nhlrc1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nhlrc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	NHLRC1	IPI	UniProtKB:O95278	Human	PMID:15930137
Molecular Function	GO:0005515	protein binding	NHLRC1	IPI	UniProtKB:P35573	Human	PMID:17908927
Molecular Function	GO:0005515	protein binding	NHLRC1	IPI	UniProtKB:O95278	Human	PMID:21505799
Molecular Function	GO:0005515	protein binding	NHLRC1	IPI	UniProtKB:Q9WUA5	Human	PMID:22578008
Molecular Function	GO:0005515	protein binding	NHLRC1	IPI	UniProtKB:O95278,UniProtKB:Q9NQV8	Human	PMID:22961547
Molecular Function	GO:0005515	protein binding	Nhlrc1	IPI	MGI:MGI:1924809	Mouse	PMID:17908927
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Nhlrc1	IDA		Mouse	PMID:17908927
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	NHLRC1	EXP		Human	PMID:15930137
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	NHLRC1	IDA		Human	PMID:15930137
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	NHLRC1	IDA		Human	PMID:18070875
Cellular Component	GO:0005634	nucleus	NHLRC1	IDA		Human	PMID:17908927
Cellular Component	GO:0005634	nucleus	Nhlrc1	IDA		Mouse	PMID:17908927
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Nhlrc1	IDA		Mouse	PMID:17908927
Biological Process	GO:0006914	autophagy	Nhlrc1	IMP	MGI:MGI:3808349	Mouse	PMID:24914213
Biological Process	GO:0005978	glycogen biosynthetic process	Nhlrc1	IMP	MGI:MGI:3808349	Mouse	PMID:20538597
Biological Process	GO:0005978	glycogen biosynthetic process	Nhlrc1	IMP	MGI:MGI:5312923	Mouse	PMID:31042462
Biological Process	GO:0005978	glycogen biosynthetic process	Nhlrc1	IGI	MGI:MGI:1341085	Mouse	PMID:28536304
Biological Process	GO:0005977	glycogen metabolic process	Nhlrc1	IMP	MGI:MGI:5312923	Mouse	PMID:23663739
Biological Process	GO:0005977	glycogen metabolic process	Nhlrc1	IMP	MGI:MGI:3808349	Mouse	PMID:25416783
Biological Process	GO:0005977	glycogen metabolic process	Nhlrc1	IMP	MGI:MGI:3808349	Mouse	PMID:24914213
Biological Process	GO:0043170	macromolecule metabolic process	Nhlrc1	IMP	MGI:MGI:5312923	Mouse	PMID:23663739
Biological Process	GO:0031398	positive regulation of protein ubiquitination	Nhlrc1	IDA		Mouse	PMID:17908927
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	NHLRC1	IDA		Human	PMID:15930137
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Nhlrc1	IMP	MGI:MGI:3808349	Mouse	PMID:24914213
Biological Process	GO:0000209	protein polyubiquitination	NHLRC1	IDA		Human	PMID:15930137
Biological Process	GO:0016567	protein ubiquitination	Nhlrc1	IDA		Mouse	PMID:17908927
Biological Process	GO:0010468	regulation of gene expression	Nhlrc1	IMP	MGI:MGI:3808349	Mouse	PMID:24914213
Biological Process	GO:0045859	regulation of protein kinase activity	Nhlrc1	IMP	MGI:MGI:3808349	Mouse	PMID:24914213
Biological Process	GO:1903076	regulation of protein localization to plasma membrane	Nhlrc1	IGI	MGI:MGI:1341085	Mouse	PMID:26976331
Biological Process	GO:0001932	regulation of protein phosphorylation	Nhlrc1	IMP	MGI:MGI:3808349	Mouse	PMID:24914213
Biological Process	GO:0031396	regulation of protein ubiquitination	Nhlrc1	IGI	MGI:MGI:1341085	Mouse	PMID:26976331
Biological Process	GO:0034976	response to endoplasmic reticulum stress	Nhlrc1	IMP	MGI:MGI:2182627	Mouse	PMID:19529779

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern