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Gene Ontology Browser
Term Detail
GO term:ubiquitin-protein ligase activity
Synonym: anaphase-promoting complex activity
Synonym: E2
Synonym: E3
Synonym: ubiquitin conjugating enzyme activity
Synonym: ubiquitin-conjugating enzyme activity
Synonym: ubiquitin ligase activity
Synonym: ubiquitin-ligase activity
Synonym: ubiquitin protein ligase activity
Synonym: ubiquitin protein-ligase activity
Synonym: ubiquitin:protein-lysine N-ligase (AMP-forming) activity
GO id:GO:0004842
Definition:Catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-aligase activity
                                is-aligase activity, forming carbon-nitrogen bonds
                                        is-aacid-amino acid ligase activity
                                                is-asmall conjugating protein ligase activity
                                                        is-aAtg12 ligase activity
                                                        is-aFAT10 ligase activity
                                                        is-aISG15 ligase activity
                                                        is-aNEDD8 ligase activity
                                                        is-aPup ligase activity
                                                        is-aSUMO ligase activity
                                                        is-aubiquitin-protein ligase activity [GO:0004842] (241 genes, 311 annotations)
                                                                is-amitotic anaphase-promoting complex activity
                                                                is-aubiquitin-calmodulin ligase activity
                                                                is-aubiquitin-ubiquitin ligase activity
                                                        is-aUFM1 conjugating enzyme activity
                                                        is-aURM1 conjugating enzyme activity


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory