Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MMP16
  • Mouse genes Mmp16
  • Rat genes Mmp16
  • Zfish genes mmp16a,mmp16b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mmp16

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070006	metalloaminopeptidase activity	MMP16	IDA		Human	PMID:24970228
Molecular Function	GO:0004222	metalloendopeptidase activity	MMP16	IDA		Human	PMID:27229514
Molecular Function	GO:0008270	zinc ion binding	MMP16	IDA		Human	PMID:27229514
Cellular Component	GO:0005886	plasma membrane	MMP16	IDA		Human	PMID:7559440
Biological Process	GO:0060348	bone development	Mmp16	IGI	MGI:MGI:101900	Mouse	PMID:18022611
Biological Process	GO:0035988	chondrocyte proliferation	Mmp16	IGI	MGI:MGI:101900	Mouse	PMID:18022611
Biological Process	GO:0030574	collagen catabolic process	Mmp16	IGI	MGI:MGI:101900	Mouse	PMID:18022611
Biological Process	GO:0030574	collagen catabolic process	Mmp16	IDA		Mouse	PMID:18022611
Biological Process	GO:0097094	craniofacial suture morphogenesis	Mmp16	IGI	MGI:MGI:101900	Mouse	PMID:18022611
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	Mmp16	IGI	MGI:MGI:101900	Mouse	PMID:18022611
Biological Process	GO:0001958	endochondral ossification	Mmp16	IGI	MGI:MGI:101900	Mouse	PMID:18022611
Biological Process	GO:0001503	ossification	Mmp16	IGI	MGI:MGI:101900	Mouse	PMID:18022611
Biological Process	GO:0016485	protein processing	MMP16	IDA		Human	PMID:27229514
Biological Process	GO:0006508	proteolysis	MMP16	IDA		Human	PMID:24970228
Biological Process	GO:1990834	response to odorant	Mmp16	IEP		Rat	PMID:23103411|RGD:11530015

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern