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Gene Ontology Browser
Term Detail
GO term:collagen catabolic process
Synonym: collagen breakdown
Synonym: collagen catabolism
Synonym: collagen degradation
GO id:GO:0030574
Definition:The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells.
Number of paths to term: 12

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acatabolic process
                                is-asingle-organism catabolic process
                                        is-a2,5-dihydroxypyridine catabolic process to fumarate
                                        is-a2-aminobenzenesulfonate catabolic process
                                        is-aacetyl-CoA assimilation pathway
                                        is-aacetylcholine catabolic process +
                                        is-aaldehyde catabolic process +
                                        is-aalkane catabolic process +
                                        is-aalkanesulfonate catabolic process
                                        is-aalkyne catabolic process +
                                        is-aatrazine catabolic process to urea
                                        is-aaustinol catabolic process
                                        is-aautophagy in response to ER overload
                                        is-acell septum edging catabolic process
                                        is-acellular lactam catabolic process +
                                        is-achondroitin sulfate catabolic process
                                        is-acollagen catabolic process [GO:0030574] (24 genes, 29 annotations)
                                                negatively-regulatesnegative regulation of collagen catabolic process
                                                regulatesregulation of collagen catabolic process +
                                        is-acyanate catabolic process
                                        is-acyanide catabolic process
                                        is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                        is-adeoxyhypusine biosynthetic process from spermidine
                                        is-adiacetylchitobiose catabolic process to glucosamine and acetate
                                        is-adibenzofuran catabolic process
                                        is-adimethylsilanediol catabolic process
                                        is-aER-associated misfolded protein catabolic process
                                        is-aether catabolic process +
                                        is-afatty acid derivative catabolic process +
                                        is-agalactosaminoglycan catabolic process
                                        is-aglutathione derivative catabolic process +
                                        is-aglycosyl compound catabolic process +
                                        is-ahalogenated hydrocarbon catabolic process +
                                        is-aheparan sulfate proteoglycan catabolic process
                                        is-aheparin catabolic process
                                        is-ahyaluronan catabolic process
                                        is-ahydrogen peroxide catabolic process +
                                        is-akeratan sulfate catabolic process
                                        is-alipid catabolic process +
                                        is-amacroautophagy +
                                        is-ameiotic DNA double-strand break processing +
                                        is-amicroautophagy +
                                        is-amulticellular organismal protein catabolic process +
                                        is-anitrate catabolic process
                                        is-anucleobase catabolic process +
                                        is-anucleoside phosphate catabolic process +
                                        is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                        is-aoctamethylcyclotetrasiloxane catabolic process to dimethylsilanediol
                                        is-aperoxisome degradation +
                                        is-aphenylpropanoid catabolic process +
                                        is-apheromone catabolic process
                                        is-apigment catabolic process +
                                        is-apolyphosphate catabolic process
                                        is-aquercetin catabolic process
                                        is-asecondary metabolite catabolic process +
                                        is-asingle-organism carbohydrate catabolic process +
                                        is-asmall molecule catabolic process +
                                        is-atartrate catabolic process


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-amulticellular organismal macromolecule metabolic process
                                                is-acollagen metabolic process
                                                        is-acollagen biosynthetic process +
                                                        is-acollagen catabolic process [GO:0030574] (24 genes, 29 annotations)
                                                                negatively-regulatesnegative regulation of collagen catabolic process
                                                                regulatesregulation of collagen catabolic process +
                                                        negatively-regulatesnegative regulation of collagen metabolic process +
                                                        positively-regulatespositive regulation of collagen metabolic process +
                                                        regulatesregulation of collagen metabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-asingle-organism metabolic process
                                is-amulticellular organismal metabolic process
                                        is-amulticellular organismal catabolic process
                                                is-acollagen catabolic process [GO:0030574] (24 genes, 29 annotations)
                                                        negatively-regulatesnegative regulation of collagen catabolic process
                                                        regulatesregulation of collagen catabolic process +
                                                is-amulticellular organismal carbohydrate catabolic process +
                                                is-amulticellular organismal lipid catabolic process +
                                                is-amulticellular organismal protein catabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-asingle-organism metabolic process
                                is-amulticellular organismal metabolic process
                                        is-amulticellular organismal macromolecule metabolic process
                                                is-acollagen metabolic process
                                                        is-acollagen biosynthetic process +
                                                        is-acollagen catabolic process [GO:0030574] (24 genes, 29 annotations)
                                                                negatively-regulatesnegative regulation of collagen catabolic process
                                                                regulatesregulation of collagen catabolic process +
                                                        negatively-regulatesnegative regulation of collagen metabolic process +
                                                        positively-regulatespositive regulation of collagen metabolic process +
                                                        regulatesregulation of collagen metabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-asingle-organism metabolic process
                                is-asingle-organism catabolic process
                                        is-a2,5-dihydroxypyridine catabolic process to fumarate
                                        is-a2-aminobenzenesulfonate catabolic process
                                        is-aacetyl-CoA assimilation pathway
                                        is-aacetylcholine catabolic process +
                                        is-aaldehyde catabolic process +
                                        is-aalkane catabolic process +
                                        is-aalkanesulfonate catabolic process
                                        is-aalkyne catabolic process +
                                        is-aatrazine catabolic process to urea
                                        is-aaustinol catabolic process
                                        is-aautophagy in response to ER overload
                                        is-acell septum edging catabolic process
                                        is-acellular lactam catabolic process +
                                        is-achondroitin sulfate catabolic process
                                        is-acollagen catabolic process [GO:0030574] (24 genes, 29 annotations)
                                                negatively-regulatesnegative regulation of collagen catabolic process
                                                regulatesregulation of collagen catabolic process +
                                        is-acyanate catabolic process
                                        is-acyanide catabolic process
                                        is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                        is-adeoxyhypusine biosynthetic process from spermidine
                                        is-adiacetylchitobiose catabolic process to glucosamine and acetate
                                        is-adibenzofuran catabolic process
                                        is-adimethylsilanediol catabolic process
                                        is-aER-associated misfolded protein catabolic process
                                        is-aether catabolic process +
                                        is-afatty acid derivative catabolic process +
                                        is-agalactosaminoglycan catabolic process
                                        is-aglutathione derivative catabolic process +
                                        is-aglycosyl compound catabolic process +
                                        is-ahalogenated hydrocarbon catabolic process +
                                        is-aheparan sulfate proteoglycan catabolic process
                                        is-aheparin catabolic process
                                        is-ahyaluronan catabolic process
                                        is-ahydrogen peroxide catabolic process +
                                        is-akeratan sulfate catabolic process
                                        is-alipid catabolic process +
                                        is-amacroautophagy +
                                        is-ameiotic DNA double-strand break processing +
                                        is-amicroautophagy +
                                        is-amulticellular organismal protein catabolic process +
                                        is-anitrate catabolic process
                                        is-anucleobase catabolic process +
                                        is-anucleoside phosphate catabolic process +
                                        is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                        is-aoctamethylcyclotetrasiloxane catabolic process to dimethylsilanediol
                                        is-aperoxisome degradation +
                                        is-aphenylpropanoid catabolic process +
                                        is-apheromone catabolic process
                                        is-apigment catabolic process +
                                        is-apolyphosphate catabolic process
                                        is-aquercetin catabolic process
                                        is-asecondary metabolite catabolic process +
                                        is-asingle-organism carbohydrate catabolic process +
                                        is-asmall molecule catabolic process +
                                        is-atartrate catabolic process


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal metabolic process
                                        is-amulticellular organismal catabolic process
                                                is-acollagen catabolic process [GO:0030574] (24 genes, 29 annotations)
                                                        negatively-regulatesnegative regulation of collagen catabolic process
                                                        regulatesregulation of collagen catabolic process +
                                                is-amulticellular organismal carbohydrate catabolic process +
                                                is-amulticellular organismal lipid catabolic process +
                                                is-amulticellular organismal protein catabolic process +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal metabolic process
                                        is-amulticellular organismal macromolecule metabolic process
                                                is-acollagen metabolic process
                                                        is-acollagen biosynthetic process +
                                                        is-acollagen catabolic process [GO:0030574] (24 genes, 29 annotations)
                                                                negatively-regulatesnegative regulation of collagen catabolic process
                                                                regulatesregulation of collagen catabolic process +
                                                        negatively-regulatesnegative regulation of collagen metabolic process +
                                                        positively-regulatespositive regulation of collagen metabolic process +
                                                        regulatesregulation of collagen metabolic process +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal metabolic process
                                        is-amulticellular organismal catabolic process
                                                is-acollagen catabolic process [GO:0030574] (24 genes, 29 annotations)
                                                        negatively-regulatesnegative regulation of collagen catabolic process
                                                        regulatesregulation of collagen catabolic process +
                                                is-amulticellular organismal carbohydrate catabolic process +
                                                is-amulticellular organismal lipid catabolic process +
                                                is-amulticellular organismal protein catabolic process +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal metabolic process
                                        is-amulticellular organismal macromolecule metabolic process
                                                is-acollagen metabolic process
                                                        is-acollagen biosynthetic process +
                                                        is-acollagen catabolic process [GO:0030574] (24 genes, 29 annotations)
                                                                negatively-regulatesnegative regulation of collagen catabolic process
                                                                regulatesregulation of collagen catabolic process +
                                                        negatively-regulatesnegative regulation of collagen metabolic process +
                                                        positively-regulatespositive regulation of collagen metabolic process +
                                                        regulatesregulation of collagen metabolic process +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism metabolic process
                                is-amulticellular organismal metabolic process
                                        is-amulticellular organismal catabolic process
                                                is-acollagen catabolic process [GO:0030574] (24 genes, 29 annotations)
                                                        negatively-regulatesnegative regulation of collagen catabolic process
                                                        regulatesregulation of collagen catabolic process +
                                                is-amulticellular organismal carbohydrate catabolic process +
                                                is-amulticellular organismal lipid catabolic process +
                                                is-amulticellular organismal protein catabolic process +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism metabolic process
                                is-amulticellular organismal metabolic process
                                        is-amulticellular organismal macromolecule metabolic process
                                                is-acollagen metabolic process
                                                        is-acollagen biosynthetic process +
                                                        is-acollagen catabolic process [GO:0030574] (24 genes, 29 annotations)
                                                                negatively-regulatesnegative regulation of collagen catabolic process
                                                                regulatesregulation of collagen catabolic process +
                                                        negatively-regulatesnegative regulation of collagen metabolic process +
                                                        positively-regulatespositive regulation of collagen metabolic process +
                                                        regulatesregulation of collagen metabolic process +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism metabolic process
                                is-asingle-organism catabolic process
                                        is-a2,5-dihydroxypyridine catabolic process to fumarate
                                        is-a2-aminobenzenesulfonate catabolic process
                                        is-aacetyl-CoA assimilation pathway
                                        is-aacetylcholine catabolic process +
                                        is-aaldehyde catabolic process +
                                        is-aalkane catabolic process +
                                        is-aalkanesulfonate catabolic process
                                        is-aalkyne catabolic process +
                                        is-aatrazine catabolic process to urea
                                        is-aaustinol catabolic process
                                        is-aautophagy in response to ER overload
                                        is-acell septum edging catabolic process
                                        is-acellular lactam catabolic process +
                                        is-achondroitin sulfate catabolic process
                                        is-acollagen catabolic process [GO:0030574] (24 genes, 29 annotations)
                                                negatively-regulatesnegative regulation of collagen catabolic process
                                                regulatesregulation of collagen catabolic process +
                                        is-acyanate catabolic process
                                        is-acyanide catabolic process
                                        is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                        is-adeoxyhypusine biosynthetic process from spermidine
                                        is-adiacetylchitobiose catabolic process to glucosamine and acetate
                                        is-adibenzofuran catabolic process
                                        is-adimethylsilanediol catabolic process
                                        is-aER-associated misfolded protein catabolic process
                                        is-aether catabolic process +
                                        is-afatty acid derivative catabolic process +
                                        is-agalactosaminoglycan catabolic process
                                        is-aglutathione derivative catabolic process +
                                        is-aglycosyl compound catabolic process +
                                        is-ahalogenated hydrocarbon catabolic process +
                                        is-aheparan sulfate proteoglycan catabolic process
                                        is-aheparin catabolic process
                                        is-ahyaluronan catabolic process
                                        is-ahydrogen peroxide catabolic process +
                                        is-akeratan sulfate catabolic process
                                        is-alipid catabolic process +
                                        is-amacroautophagy +
                                        is-ameiotic DNA double-strand break processing +
                                        is-amicroautophagy +
                                        is-amulticellular organismal protein catabolic process +
                                        is-anitrate catabolic process
                                        is-anucleobase catabolic process +
                                        is-anucleoside phosphate catabolic process +
                                        is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                        is-aoctamethylcyclotetrasiloxane catabolic process to dimethylsilanediol
                                        is-aperoxisome degradation +
                                        is-aphenylpropanoid catabolic process +
                                        is-apheromone catabolic process
                                        is-apigment catabolic process +
                                        is-apolyphosphate catabolic process
                                        is-aquercetin catabolic process
                                        is-asecondary metabolite catabolic process +
                                        is-asingle-organism carbohydrate catabolic process +
                                        is-asmall molecule catabolic process +
                                        is-atartrate catabolic process


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory