Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Mafb

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes MAFB
- Mouse genes Mafb
- Rat genes Mafb
- Zfish genes mafba
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mafb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Mafb	IDA		Mouse	PMID:12701106
Molecular Function	GO:0003677	DNA binding	Mafb	IDA		Mouse	PMID:12798298
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Mafb	IMP		Mouse	MGI:MGI:2660991\|PMID:12701106
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Mafb	IDA		Rat	PMID:9571165\|RGD:1547884
Molecular Function	GO:0042802	identical protein binding	MAFB	IPI	UniProtKB:Q9Y5Q3	Human	PMID:20102225
Molecular Function	GO:0042802	identical protein binding	MAFB	IPI	UniProtKB:Q9Y5Q3	Human	PMID:20211142
Molecular Function	GO:0042802	identical protein binding	MAFB	IPI	UniProtKB:Q9Y5Q3	Human	PMID:23661758
Molecular Function	GO:0042802	identical protein binding	Mafb	IPI	RGD:2982	Rat	PMID:9571165\|RGD:1547884
Molecular Function	GO:0005515	protein binding	MAFB	IPI	UniProtKB:O14867	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	MAFB	IPI	UniProtKB:O75444	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	MAFB	IPI	UniProtKB:P01100	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	MAFB	IPI	UniProtKB:P0C746	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	MAFB	IPI	UniProtKB:Q14653	Human	PMID:20581830
Molecular Function	GO:0005515	protein binding	MAFB	IPI	UniProtKB:O14867	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	MAFB	IPI	UniProtKB:O75444	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	MAFB	IPI	UniProtKB:P01100	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	MAFB	IPI	UniProtKB:Q9BYR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Mafb	IPI	UniProtKB:P01101	Mouse	MGI:MGI:5926790\|PMID:24530283
Molecular Function	GO:0005515	protein binding	Mafb	IPI	PR:P05627	Mouse	PMID:12798298
Molecular Function	GO:0005515	protein binding	Mafb	IPI	UniProtKB:P12841	Rat	PMID:9571165\|RGD:1547884
Molecular Function	GO:0044877	protein-containing complex binding	Mafb	IDA		Rat	PMID:9571165\|RGD:1547884
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Mafb	IMP		Mouse	MGI:MGI:2660991\|PMID:12701106
Molecular Function	GO:0043565	sequence-specific DNA binding	Mafb	IDA		Mouse	MGI:MGI:6393337\|PMID:11823429
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	Mafb	IDA		Rat	PMID:9571165\|RGD:1547884
Cellular Component	GO:0005634	nucleus	MAFB	IDA		Human	PMID:27208706
Cellular Component	GO:0005634	nucleus	Mafb	IDA		Mouse	PMID:17928203
Cellular Component	GO:0005634	nucleus	Mafb	IDA		Mouse	PMID:12917329
Cellular Component	GO:0005634	nucleus	Mafb	IDA		Rat	PMID:9038383\|RGD:69874
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	MAFB	IPI		Human	PMID:23661758
Cellular Component	GO:0005667	transcription regulator complex	Mafb	IDA		Mouse	PMID:12798298
Biological Process	GO:0021599	abducens nerve formation	Mafb	IMP		Mouse	MGI:MGI:5816405\|PMID:27181683
Biological Process	GO:0021742	abducens nucleus development	mafba	IMP	ZFIN:ZDB-GENO-190508-18	Zfish	PMID:30089266
Biological Process	GO:0009952	anterior/posterior pattern specification	mafba	IMP	ZFIN:ZDB-GENO-970731-9	Zfish	PMID:15342476
Biological Process	GO:0035284	brain segmentation	Mafb	IMP	MGI:MGI:1856419	Mouse	PMID:7925021
Biological Process	GO:1903575	cornified envelope assembly	Mafb	IMP	MGI:MGI:3663168	Mouse	PMID:27208706
Biological Process	GO:0009880	embryonic pattern specification	mafba	IMP	ZFIN:ZDB-GENO-970731-9	Zfish	PMID:15366005
Biological Process	GO:0010467	gene expression	Mafb	IMP	MGI:MGI:3663168	Mouse	PMID:27208706
Biological Process	GO:0042472	inner ear morphogenesis	Mafb	IMP	MGI:MGI:1856419	Mouse	PMID:16325169
Biological Process	GO:0030216	keratinocyte differentiation	Mafb	IMP	MGI:MGI:3663168	Mouse	PMID:27208706
Biological Process	GO:0001946	lymphangiogenesis	mafba	IMP	ZFIN:ZDB-GENO-151231-11	Zfish	PMID:26253536
Biological Process	GO:0045647	negative regulation of erythrocyte differentiation	MAFB	IDA		Human	PMID:8620536
Biological Process	GO:0045671	negative regulation of osteoclast differentiation	Mafb	IDA		Mouse	MGI:MGI:3849531\|PMID:19440205
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Mafb	IDA		Mouse	MGI:MGI:6393337\|PMID:11823429
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mafb	IMP		Mouse	MGI:MGI:2660991\|PMID:12701106
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mafb	IDA		Mouse	PMID:12798298
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mafb	IDA		Rat	PMID:9571165\|RGD:1547884
Biological Process	GO:0039021	pronephric glomerulus development	mafba	IMP		Zfish	PMID:25556170
Biological Process	GO:0016485	protein processing	Mafb	IMP	MGI:MGI:3663168	Mouse	PMID:27208706
Biological Process	GO:0006355	regulation of DNA-templated transcription	MAFB	IMP		Human	PMID:27181683
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Mafb	IDA		Mouse	PMID:12701106
Biological Process	GO:0007585	respiratory gaseous exchange by respiratory system	Mafb	IMP	MGI:MGI:2677917	Mouse	PMID:14513037
Biological Process	GO:0046548	retinal rod cell development	mafba	IGI	ZFIN:ZDB-GENO-221220-4	Zfish	PMID:35245286
Biological Process	GO:0046548	retinal rod cell development	mafba	IGI	ZFIN:ZDB-GENO-221220-3	Zfish	PMID:35245286
Biological Process	GO:0021571	rhombomere 5 development	Mafb	IMP	MGI:MGI:1856419	Mouse	PMID:7925021
Biological Process	GO:0021571	rhombomere 5 development	mafba	IMP	ZFIN:ZDB-GENO-090923-1	Zfish	PMID:29945667
Biological Process	GO:0021571	rhombomere 5 development	mafba	IMP	ZFIN:ZDB-GENO-970731-9	Zfish	PMID:9012518
Biological Process	GO:0021572	rhombomere 6 development	Mafb	IMP	MGI:MGI:1856419	Mouse	PMID:7925021
Biological Process	GO:0021572	rhombomere 6 development	mafba	IMP	ZFIN:ZDB-GENO-970731-9	Zfish	PMID:9012518
Biological Process	GO:0021572	rhombomere 6 development	mafba	IMP	ZFIN:ZDB-GENO-090923-1	Zfish	PMID:29945667
Biological Process	GO:0021654	rhombomere boundary formation	mafba	IMP	ZFIN:ZDB-GENO-970731-9	Zfish	PMID:9012518
Biological Process	GO:0021654	rhombomere boundary formation	mafba	IMP	ZFIN:ZDB-GENO-970731-9	Zfish	PMID:9425134
Biological Process	GO:0007379	segment specification	Mafb	IMP	MGI:MGI:2157803	Mouse	PMID:12701106
Biological Process	GO:0033077	T cell differentiation in thymus	Mafb	IMP	MGI:MGI:3663168	Mouse	PMID:19164599
Biological Process	GO:0048538	thymus development	Mafb	IMP	MGI:MGI:3663168	Mouse	PMID:19164599

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.