Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LCP1
  • Mouse genes Lcp1
  • Rat genes Lcp1
  • Zfish genes lcp1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lcp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	LCP1	IMP		Human	PMID:16636079
Molecular Function	GO:0051015	actin filament binding	Lcp1	IDA		Mouse	PMID:14756805
Molecular Function	GO:0051020	GTPase binding	LCP1	IPI	UniProtKB:P32455	Human	PMID:24337748
Molecular Function	GO:0005178	integrin binding	LCP1	IPI	UniProtKB:P05107	Human	PMID:20183869
Molecular Function	GO:0005178	integrin binding	LCP1	IPI	UniProtKB:P05556	Human	PMID:20183869
Molecular Function	GO:0005515	protein binding	Lcp1	IPI	UniProtKB:P47811	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0005515	protein binding	Lcp1	IPI	PR:O70200	Mouse	PMID:14756805
Cellular Component	GO:0015629	actin cytoskeleton	LCP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0015629	actin cytoskeleton	Lcp1	IDA		Mouse	PMID:7655078
Cellular Component	GO:0005884	actin filament	LCP1	IMP		Human	PMID:16636079
Cellular Component	GO:0005884	actin filament	Lcp1	IDA		Mouse	PMID:14756805
Cellular Component	GO:0032432	actin filament bundle	LCP1	IMP		Human	PMID:16636079
Cellular Component	GO:0005737	cytoplasm	LCP1	IDA		Human	PMID:16636079
Cellular Component	GO:0005737	cytoplasm	Lcp1	IDA		Mouse	PMID:14756805
Cellular Component	GO:0005737	cytoplasm	lcp1	IDA		Zfish	PMID:19097072
Cellular Component	GO:0005829	cytosol	LCP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	LCP1	IDA		Human	PMID:17294403
Cellular Component	GO:0005829	cytosol	LCP1	IDA		Human	PMID:2111166
Cellular Component	GO:0070062	extracellular exosome	LCP1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	LCP1	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	LCP1	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	LCP1	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	LCP1	HDA		Human	PMID:22664934
Cellular Component	GO:0030175	filopodium	LCP1	IMP		Human	PMID:16636079
Cellular Component	GO:0005925	focal adhesion	LCP1	IMP		Human	PMID:16636079
Cellular Component	GO:0097386	glial cell projection	Lcp1	IDA		Mouse	PMID:14756805
Cellular Component	GO:0048471	perinuclear region of cytoplasm	LCP1	IDA		Human	PMID:20183869
Cellular Component	GO:0001891	phagocytic cup	Lcp1	IDA		Mouse	PMID:14756805
Cellular Component	GO:0005886	plasma membrane	LCP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0002102	podosome	LCP1	IDA		Human	PMID:24236012
Cellular Component	GO:0001726	ruffle	LCP1	IMP		Human	PMID:16636079
Cellular Component	GO:0001726	ruffle	Lcp1	IDA		Mouse	PMID:14756805
Cellular Component	GO:0001725	stress fiber	LCP1	IMP		Human	PMID:16636079
Biological Process	GO:0051017	actin filament bundle assembly	LCP1	IMP		Human	PMID:16636079
Biological Process	GO:0051017	actin filament bundle assembly	Lcp1	IDA		Mouse	PMID:14756805
Biological Process	GO:0031100	animal organ regeneration	Lcp1	IEP		Rat	PMID:16626512|RGD:1599814
Biological Process	GO:0016477	cell migration	LCP1	IMP		Human	PMID:16636079
Biological Process	GO:0022617	extracellular matrix disassembly	LCP1	IMP		Human	PMID:24236012
Biological Process	GO:0071803	positive regulation of podosome assembly	LCP1	IMP		Human	PMID:24236012
Biological Process	GO:0010737	protein kinase A signaling	LCP1	IMP		Human	PMID:16636079
Biological Process	GO:0033157	regulation of intracellular protein transport	LCP1	IDA		Human	PMID:17294403
Biological Process	GO:0002286	T cell activation involved in immune response	LCP1	IDA		Human	PMID:17294403

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern