Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KISS1R
  • Mouse genes Kiss1r
  • Rat genes Kiss1r
  • Zfish genes kiss1ra,kiss1rb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kiss1r

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008528	G protein-coupled peptide receptor activity	Kiss1r	IDA		Mouse	PMID:11414709
Molecular Function	GO:0008528	G protein-coupled peptide receptor activity	Kiss1r	IPI	RGD:1352127	Rat	PMID:11457843|RGD:1357971
Molecular Function	GO:0042923	neuropeptide binding	Kiss1r	IDA		Rat	PMID:11414709|RGD:1599294
Molecular Function	GO:0008188	neuropeptide receptor activity	KISS1R	IDA		Human	PMID:11387329
Molecular Function	GO:0008188	neuropeptide receptor activity	kiss1rb	IDA		Zfish	PMID:22499582
Molecular Function	GO:0008188	neuropeptide receptor activity	kiss1rb	IDA		Zfish	PMID:18509165
Molecular Function	GO:0008188	neuropeptide receptor activity	kiss1ra	IDA		Zfish	PMID:22499582
Molecular Function	GO:0008188	neuropeptide receptor activity	kiss1ra	IDA		Zfish	PMID:18509165
Molecular Function	GO:0005515	protein binding	KISS1R	IPI	UniProtKB:Q15726	Human	PMID:11387329
Molecular Function	GO:0005515	protein binding	KISS1R	IPI	UniProtKB:P50148	Human	PMID:18772143
Molecular Function	GO:0005515	protein binding	KISS1R	IPI	UniProtKB:P67775	Human	PMID:18977201
Molecular Function	GO:0005515	protein binding	Kiss1r	IPI	PR:Q6Y4S4	Mouse	PMID:12359743
Cellular Component	GO:0009986	cell surface	Kiss1r	IDA		Mouse	PMID:12359743
Cellular Component	GO:0009986	cell surface	kiss1rb	IDA		Zfish	PMID:22499582
Cellular Component	GO:0009986	cell surface	kiss1ra	IDA		Zfish	PMID:22499582
Cellular Component	GO:0005929	cilium	KISS1R	IDA		Human	PMID:28154160
Cellular Component	GO:0005737	cytoplasm	kiss1rb	IDA		Zfish	PMID:22499582
Cellular Component	GO:0005737	cytoplasm	kiss1ra	IDA		Zfish	PMID:22499582
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	KISS1R	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	KISS1R	IDA		Human	PMID:11387329
Cellular Component	GO:0016020	membrane	Kiss1r	IDA		Rat	PMID:11457843|RGD:1357971
Cellular Component	GO:0005634	nucleus	kiss1rb	IDA		Zfish	PMID:22499582
Cellular Component	GO:0005886	plasma membrane	KISS1R	IDA		Human	GO_REF:0000052
Biological Process	GO:0050482	arachidonic acid secretion	Kiss1r	IDA		Rat	PMID:11457843|RGD:1357971
Biological Process	GO:0019722	calcium-mediated signaling	Kiss1r	IMP		Rat	PMID:16222076|RGD:1599289
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Kiss1r	IMP		Rat	PMID:16222076|RGD:1599289
Biological Process	GO:0030336	negative regulation of cell migration	Kiss1r	IPI	UniProtKB:Q80XF6	Mouse	PMID:12359743
Biological Process	GO:0008285	negative regulation of cell population proliferation	Kiss1r	IPI	UniProtKB:Q80XF6	Mouse	PMID:12359743
Biological Process	GO:0008285	negative regulation of cell population proliferation	Kiss1r	IDA		Rat	PMID:11457843|RGD:1357971
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	kiss1rb	IDA		Zfish	PMID:22499582
Biological Process	GO:0046887	positive regulation of hormone secretion	Kiss1r	IDA		Rat	PMID:11457843|RGD:1357971
Biological Process	GO:0043410	positive regulation of MAPK cascade	Kiss1r	IDA		Rat	PMID:11457843|RGD:1357971
Biological Process	GO:0051496	positive regulation of stress fiber assembly	Kiss1r	IDA		Rat	PMID:11457843|RGD:1357971
Biological Process	GO:0050806	positive regulation of synaptic transmission	Kiss1r	IMP		Rat	PMID:16222076|RGD:1599289
Biological Process	GO:0007165	signal transduction	Kiss1r	IDA		Mouse	PMID:11414709

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern