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Gene Ontology Browser
Term Detail
GO term:calcium-mediated signaling
Synonym: calcium ion signaling
Synonym: calcium-mediated signalling
Synonym: calcium signaling
Synonym: calcium signalling
GO id:GO:0019722
Definition:Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.
Number of paths to term: 9

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-aintracellular signal transduction
                                                        is-asecond-messenger-mediated signaling
                                                                is-acalcium-mediated signaling [GO:0019722] (94 genes, 112 annotations)
                                                                        is-aactivation of phospholipase A2 activity by calcium-mediated signaling
                                                                        is-acalcineurin-NFAT signaling cascade +
                                                                        is-acalcium-mediated signaling using extracellular calcium source
                                                                        is-acalcium-mediated signaling using intracellular calcium source
                                                                        is-acytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration
                                                                        negatively-regulatesnegative regulation of calcium-mediated signaling +
                                                                        positively-regulatespositive regulation of calcium-mediated signaling +
                                                                        is-apositive regulation of cerebellar granule cell migration by calcium
                                                                        regulatesregulation of calcium-mediated signaling +
                                                                        is-aregulation of cardiac muscle contraction by calcium ion signaling +
                                                                        is-aregulation of skeletal muscle contraction by calcium ion signaling +
                                                                        is-aregulation of transcription from RNA polymerase II promoter by calcium-mediated signaling +
                                                                is-acyclic-nucleotide-mediated signaling +
                                                                is-ainositol phosphate-mediated signaling +
                                                                is-anitric oxide mediated signal transduction +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-asecond-messenger-mediated signaling
                                                        is-acalcium-mediated signaling [GO:0019722] (94 genes, 112 annotations)
                                                                is-aactivation of phospholipase A2 activity by calcium-mediated signaling
                                                                is-acalcineurin-NFAT signaling cascade +
                                                                is-acalcium-mediated signaling using extracellular calcium source
                                                                is-acalcium-mediated signaling using intracellular calcium source
                                                                is-acytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration
                                                                negatively-regulatesnegative regulation of calcium-mediated signaling +
                                                                positively-regulatespositive regulation of calcium-mediated signaling +
                                                                is-apositive regulation of cerebellar granule cell migration by calcium
                                                                regulatesregulation of calcium-mediated signaling +
                                                                is-aregulation of cardiac muscle contraction by calcium ion signaling +
                                                                is-aregulation of skeletal muscle contraction by calcium ion signaling +
                                                                is-aregulation of transcription from RNA polymerase II promoter by calcium-mediated signaling +
                                                        is-acyclic-nucleotide-mediated signaling +
                                                        is-ainositol phosphate-mediated signaling +
                                                        is-anitric oxide mediated signal transduction +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-asecond-messenger-mediated signaling
                                                        is-acalcium-mediated signaling [GO:0019722] (94 genes, 112 annotations)
                                                                is-aactivation of phospholipase A2 activity by calcium-mediated signaling
                                                                is-acalcineurin-NFAT signaling cascade +
                                                                is-acalcium-mediated signaling using extracellular calcium source
                                                                is-acalcium-mediated signaling using intracellular calcium source
                                                                is-acytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration
                                                                negatively-regulatesnegative regulation of calcium-mediated signaling +
                                                                positively-regulatespositive regulation of calcium-mediated signaling +
                                                                is-apositive regulation of cerebellar granule cell migration by calcium
                                                                regulatesregulation of calcium-mediated signaling +
                                                                is-aregulation of cardiac muscle contraction by calcium ion signaling +
                                                                is-aregulation of skeletal muscle contraction by calcium ion signaling +
                                                                is-aregulation of transcription from RNA polymerase II promoter by calcium-mediated signaling +
                                                        is-acyclic-nucleotide-mediated signaling +
                                                        is-ainositol phosphate-mediated signaling +
                                                        is-anitric oxide mediated signal transduction +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-aintracellular signal transduction
                                                        is-asecond-messenger-mediated signaling
                                                                is-acalcium-mediated signaling [GO:0019722] (94 genes, 112 annotations)
                                                                        is-aactivation of phospholipase A2 activity by calcium-mediated signaling
                                                                        is-acalcineurin-NFAT signaling cascade +
                                                                        is-acalcium-mediated signaling using extracellular calcium source
                                                                        is-acalcium-mediated signaling using intracellular calcium source
                                                                        is-acytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration
                                                                        negatively-regulatesnegative regulation of calcium-mediated signaling +
                                                                        positively-regulatespositive regulation of calcium-mediated signaling +
                                                                        is-apositive regulation of cerebellar granule cell migration by calcium
                                                                        regulatesregulation of calcium-mediated signaling +
                                                                        is-aregulation of cardiac muscle contraction by calcium ion signaling +
                                                                        is-aregulation of skeletal muscle contraction by calcium ion signaling +
                                                                        is-aregulation of transcription from RNA polymerase II promoter by calcium-mediated signaling +
                                                                is-acyclic-nucleotide-mediated signaling +
                                                                is-ainositol phosphate-mediated signaling +
                                                                is-anitric oxide mediated signal transduction +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-asecond-messenger-mediated signaling
                                                        is-acalcium-mediated signaling [GO:0019722] (94 genes, 112 annotations)
                                                                is-aactivation of phospholipase A2 activity by calcium-mediated signaling
                                                                is-acalcineurin-NFAT signaling cascade +
                                                                is-acalcium-mediated signaling using extracellular calcium source
                                                                is-acalcium-mediated signaling using intracellular calcium source
                                                                is-acytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration
                                                                negatively-regulatesnegative regulation of calcium-mediated signaling +
                                                                positively-regulatespositive regulation of calcium-mediated signaling +
                                                                is-apositive regulation of cerebellar granule cell migration by calcium
                                                                regulatesregulation of calcium-mediated signaling +
                                                                is-aregulation of cardiac muscle contraction by calcium ion signaling +
                                                                is-aregulation of skeletal muscle contraction by calcium ion signaling +
                                                                is-aregulation of transcription from RNA polymerase II promoter by calcium-mediated signaling +
                                                        is-acyclic-nucleotide-mediated signaling +
                                                        is-ainositol phosphate-mediated signaling +
                                                        is-anitric oxide mediated signal transduction +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-asecond-messenger-mediated signaling
                                                        is-acalcium-mediated signaling [GO:0019722] (94 genes, 112 annotations)
                                                                is-aactivation of phospholipase A2 activity by calcium-mediated signaling
                                                                is-acalcineurin-NFAT signaling cascade +
                                                                is-acalcium-mediated signaling using extracellular calcium source
                                                                is-acalcium-mediated signaling using intracellular calcium source
                                                                is-acytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration
                                                                negatively-regulatesnegative regulation of calcium-mediated signaling +
                                                                positively-regulatespositive regulation of calcium-mediated signaling +
                                                                is-apositive regulation of cerebellar granule cell migration by calcium
                                                                regulatesregulation of calcium-mediated signaling +
                                                                is-aregulation of cardiac muscle contraction by calcium ion signaling +
                                                                is-aregulation of skeletal muscle contraction by calcium ion signaling +
                                                                is-aregulation of transcription from RNA polymerase II promoter by calcium-mediated signaling +
                                                        is-acyclic-nucleotide-mediated signaling +
                                                        is-ainositol phosphate-mediated signaling +
                                                        is-anitric oxide mediated signal transduction +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-aintracellular signal transduction
                                                is-asecond-messenger-mediated signaling
                                                        is-acalcium-mediated signaling [GO:0019722] (94 genes, 112 annotations)
                                                                is-aactivation of phospholipase A2 activity by calcium-mediated signaling
                                                                is-acalcineurin-NFAT signaling cascade +
                                                                is-acalcium-mediated signaling using extracellular calcium source
                                                                is-acalcium-mediated signaling using intracellular calcium source
                                                                is-acytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration
                                                                negatively-regulatesnegative regulation of calcium-mediated signaling +
                                                                positively-regulatespositive regulation of calcium-mediated signaling +
                                                                is-apositive regulation of cerebellar granule cell migration by calcium
                                                                regulatesregulation of calcium-mediated signaling +
                                                                is-aregulation of cardiac muscle contraction by calcium ion signaling +
                                                                is-aregulation of skeletal muscle contraction by calcium ion signaling +
                                                                is-aregulation of transcription from RNA polymerase II promoter by calcium-mediated signaling +
                                                        is-acyclic-nucleotide-mediated signaling +
                                                        is-ainositol phosphate-mediated signaling +
                                                        is-anitric oxide mediated signal transduction +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-aintracellular signal transduction
                                                is-asecond-messenger-mediated signaling
                                                        is-acalcium-mediated signaling [GO:0019722] (94 genes, 112 annotations)
                                                                is-aactivation of phospholipase A2 activity by calcium-mediated signaling
                                                                is-acalcineurin-NFAT signaling cascade +
                                                                is-acalcium-mediated signaling using extracellular calcium source
                                                                is-acalcium-mediated signaling using intracellular calcium source
                                                                is-acytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration
                                                                negatively-regulatesnegative regulation of calcium-mediated signaling +
                                                                positively-regulatespositive regulation of calcium-mediated signaling +
                                                                is-apositive regulation of cerebellar granule cell migration by calcium
                                                                regulatesregulation of calcium-mediated signaling +
                                                                is-aregulation of cardiac muscle contraction by calcium ion signaling +
                                                                is-aregulation of skeletal muscle contraction by calcium ion signaling +
                                                                is-aregulation of transcription from RNA polymerase II promoter by calcium-mediated signaling +
                                                        is-acyclic-nucleotide-mediated signaling +
                                                        is-ainositol phosphate-mediated signaling +
                                                        is-anitric oxide mediated signal transduction +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-aintracellular signal transduction
                                                        is-asecond-messenger-mediated signaling
                                                                is-acalcium-mediated signaling [GO:0019722] (94 genes, 112 annotations)
                                                                        is-aactivation of phospholipase A2 activity by calcium-mediated signaling
                                                                        is-acalcineurin-NFAT signaling cascade +
                                                                        is-acalcium-mediated signaling using extracellular calcium source
                                                                        is-acalcium-mediated signaling using intracellular calcium source
                                                                        is-acytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration
                                                                        negatively-regulatesnegative regulation of calcium-mediated signaling +
                                                                        positively-regulatespositive regulation of calcium-mediated signaling +
                                                                        is-apositive regulation of cerebellar granule cell migration by calcium
                                                                        regulatesregulation of calcium-mediated signaling +
                                                                        is-aregulation of cardiac muscle contraction by calcium ion signaling +
                                                                        is-aregulation of skeletal muscle contraction by calcium ion signaling +
                                                                        is-aregulation of transcription from RNA polymerase II promoter by calcium-mediated signaling +
                                                                is-acyclic-nucleotide-mediated signaling +
                                                                is-ainositol phosphate-mediated signaling +
                                                                is-anitric oxide mediated signal transduction +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory