Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Kcnma1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes KCNMA1
- Mouse genes Kcnma1
- Rat genes Kcnma1
- Zfish genes kcnma1a,kcnma1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnma1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	KCNMA1	IDA		Human	PMID:15703204
Molecular Function	GO:0015269	calcium-activated potassium channel activity	KCNMA1	IDA		Human	PMID:11245614
Molecular Function	GO:0015269	calcium-activated potassium channel activity	KCNMA1	IDA		Human	PMID:17706472
Molecular Function	GO:0015269	calcium-activated potassium channel activity	KCNMA1	IDA		Human	PMID:18458941
Molecular Function	GO:0015269	calcium-activated potassium channel activity	KCNMA1	IDA		Human	PMID:7573516
Molecular Function	GO:0015269	calcium-activated potassium channel activity	KCNMA1	IDA		Human	PMID:7877450
Molecular Function	GO:0015269	calcium-activated potassium channel activity	Kcnma1	IGI	MGI:MGI:1913272	Mouse	PMID:12388098
Molecular Function	GO:0015269	calcium-activated potassium channel activity	Kcnma1	IGI	MGI:MGI:1334203	Mouse	PMID:12388098
Molecular Function	GO:0015269	calcium-activated potassium channel activity	Kcnma1	IDA		Mouse	PMID:17303127
Molecular Function	GO:0015269	calcium-activated potassium channel activity	Kcnma1	IDA		Mouse	PMID:10517674
Molecular Function	GO:0015269	calcium-activated potassium channel activity	Kcnma1	IDA		Mouse	PMID:16306267
Molecular Function	GO:0015269	calcium-activated potassium channel activity	Kcnma1	IDA		Mouse	PMID:7687074
Molecular Function	GO:0015269	calcium-activated potassium channel activity	Kcnma1	IMP	MGI:MGI:3053849	Mouse	PMID:15184377
Molecular Function	GO:0015269	calcium-activated potassium channel activity	Kcnma1	IDA		Rat	PMID:11964233\|RGD:633136
Molecular Function	GO:0042802	identical protein binding	Kcnma1	IDA		Mouse	PMID:17303127
Molecular Function	GO:0042802	identical protein binding	Kcnma1	IPI	RGD:620715	Rat	PMID:16045448\|RGD:1581583
Molecular Function	GO:0060072	large conductance calcium-activated potassium channel activity	KCNMA1	IMP		Human	PMID:15703204
Molecular Function	GO:0060072	large conductance calcium-activated potassium channel activity	KCNMA1	IDA		Human	PMID:7993625
Molecular Function	GO:0060072	large conductance calcium-activated potassium channel activity	Kcnma1	IMP		Mouse	MGI:MGI:5560378\|PMID:24602615
Molecular Function	GO:0060072	large conductance calcium-activated potassium channel activity	Kcnma1	IMP	MGI:MGI:3053849	Mouse	PMID:16873365
Molecular Function	GO:0060072	large conductance calcium-activated potassium channel activity	Kcnma1	IDA		Mouse	PMID:12388098
Molecular Function	GO:0060072	large conductance calcium-activated potassium channel activity	Kcnma1	IDA		Rat	PMID:17068255\|RGD:7205477
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	Kcnma1	EXP		Rat	PMID:11739569\|RGD:1581587
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	Kcnma1	IDA		Rat	PMID:11739569\|RGD:1581587
Molecular Function	GO:0005267	potassium channel activity	Kcnma1	IGI	MGI:MGI:1277957	Mouse	PMID:16873365
Molecular Function	GO:0005267	potassium channel activity	Kcnma1	IMP	MGI:MGI:3053849	Mouse	PMID:17135251
Molecular Function	GO:0005515	protein binding	KCNMA1	IPI	UniProtKB:Q86W47	Human	PMID:10692449
Molecular Function	GO:0005515	protein binding	KCNMA1	IPI	UniProtKB:P19440	Human	PMID:15528406
Molecular Function	GO:0005515	protein binding	KCNMA1	IPI	UniProtKB:P30519	Human	PMID:15528406
Molecular Function	GO:0005515	protein binding	KCNMA1	IPI	UniProtKB:P51636	Human	PMID:15703204
Molecular Function	GO:0005515	protein binding	KCNMA1	IPI	UniProtKB:Q03135	Human	PMID:15703204
Molecular Function	GO:0005515	protein binding	KCNMA1	IPI	UniProtKB:Q6NXK8-1	Human	PMID:18287010
Molecular Function	GO:0005515	protein binding	KCNMA1	IPI	UniProtKB:Q2I0M4	Human	PMID:20613726
Molecular Function	GO:0005515	protein binding	KCNMA1	IPI	UniProtKB:Q2I0M4	Human	PMID:22547800
Molecular Function	GO:0005515	protein binding	KCNMA1	IPI	UniProtKB:Q5VT99	Human	PMID:22547800
Molecular Function	GO:0005515	protein binding	KCNMA1	IPI	UniProtKB:Q6ZSA7	Human	PMID:22547800
Molecular Function	GO:0005515	protein binding	KCNMA1	IPI	UniProtKB:Q8N7C0	Human	PMID:22547800
Molecular Function	GO:0005515	protein binding	Kcnma1	IPI	UniProtKB:O88952\|UniProtKB:P27573\|UniProtKB:P48036\|UniProtKB:P61982\|UniProtKB:P63260\|UniProtKB:Q00623	Mouse	MGI:MGI:3852248\|PMID:19423573
Molecular Function	GO:0005515	protein binding	Kcnma1	IPI	UniProtKB:P16858\|UniProtKB:P84075	Mouse	MGI:MGI:3852248\|PMID:19423573
Molecular Function	GO:0005515	protein binding	Kcnma1	IPI	UniProtKB:P08251	Mouse	MGI:MGI:4366208\|PMID:19729011
Molecular Function	GO:0005515	protein binding	Kcnma1	IPI	UniProtKB:O75791\|UniProtKB:P46109\|UniProtKB:Q14247\|UniProtKB:Q60598	Mouse	MGI:MGI:5508620\|PMID:17065230
Molecular Function	GO:0005515	protein binding	Kcnma1	IPI	UniProtKB:Q8CAE3	Mouse	MGI:MGI:6093438\|PMID:16549765
Molecular Function	GO:0005515	protein binding	Kcnma1	IPI	RGD:1310533	Rat	PMID:16045448\|RGD:1581583
Molecular Function	GO:0005515	protein binding	Kcnma1	IPI	UniProtKB:P02688	Rat	PMID:17610306\|RGD:8554328
Molecular Function	GO:0005515	protein binding	Kcnma1	IPI	RGD:3825	Rat	PMID:20959415\|RGD:11059604
Molecular Function	GO:0044877	protein-containing complex binding	Kcnma1	IPI	RGD:620829\|RGD:2060	Rat	PMID:15141163\|RGD:2313233
Molecular Function	GO:0005249	voltage-gated potassium channel activity	KCNMA1	IDA		Human	PMID:12388065
Molecular Function	GO:0005249	voltage-gated potassium channel activity	KCNMA1	IMP		Human	PMID:31152168
Molecular Function	GO:0005249	voltage-gated potassium channel activity	KCNMA1	IDA		Human	PMID:7877450
Molecular Function	GO:0005249	voltage-gated potassium channel activity	Kcnma1	IMP	MGI:MGI:3053849	Mouse	PMID:15184377
Molecular Function	GO:0005249	voltage-gated potassium channel activity	Kcnma1	IDA		Mouse	PMID:7687074
Cellular Component	GO:0016324	apical plasma membrane	KCNMA1	IDA		Human	PMID:10840032
Cellular Component	GO:0016324	apical plasma membrane	Kcnma1	IDA		Mouse	PMID:17135251
Cellular Component	GO:0005901	caveola	KCNMA1	IDA		Human	PMID:15703204
Cellular Component	GO:0030425	dendrite	Kcnma1	IDA		Rat	PMID:16045448\|RGD:1581583
Cellular Component	GO:0005783	endoplasmic reticulum	Kcnma1	IDA		Mouse	PMID:17303127
Cellular Component	GO:0009897	external side of plasma membrane	Kcnma1	IDA		Mouse	PMID:17303127
Cellular Component	GO:0009897	external side of plasma membrane	Kcnma1	IDA		Rat	PMID:16045448\|RGD:1581583
Cellular Component	GO:0098978	glutamatergic synapse	Kcnma1	EXP		Rat	PMID:11739569\|RGD:1581587
Cellular Component	GO:0098978	glutamatergic synapse	Kcnma1	IDA		Rat	PMID:11739569\|RGD:1581587
Cellular Component	GO:0016020	membrane	KCNMA1	IDA		Human	PMID:7573516
Cellular Component	GO:0016020	membrane	KCNMA1	IDA		Human	PMID:7877450
Cellular Component	GO:0016020	membrane	Kcnma1	IDA		Mouse	PMID:12388098
Cellular Component	GO:0005739	mitochondrion	Kcnma1	IDA		Rat	PMID:23754429\|RGD:10412029
Cellular Component	GO:0043025	neuronal cell body	Kcnma1	IDA		Rat	PMID:16045448\|RGD:1581583
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Kcnma1	IDA		Rat	PMID:10384881\|RGD:1581589
Cellular Component	GO:0005886	plasma membrane	Kcnma1	IDA		Mouse	PMID:10517674
Cellular Component	GO:0005886	plasma membrane	Kcnma1	IDA		Mouse	PMID:12952984
Cellular Component	GO:0005886	plasma membrane	Kcnma1	IDA		Rat	PMID:10384881\|RGD:1581589
Cellular Component	GO:0005886	plasma membrane	Kcnma1	IDA		Rat	PMID:17068255\|RGD:7205477
Cellular Component	GO:0045211	postsynaptic membrane	Kcnma1	IDA		Mouse	PMID:15328414
Cellular Component	GO:0048787	presynaptic active zone membrane	Kcnma1	IDA		Rat	PMID:11739569\|RGD:1581587
Cellular Component	GO:0032991	protein-containing complex	Kcnma1	IDA		Rat	PMID:17068255\|RGD:7205477
Cellular Component	GO:0016528	sarcoplasm	Kcnma1	IDA		Mouse	PMID:12952984
Cellular Component	GO:0043195	terminal bouton	Kcnma1	IDA		Mouse	PMID:15328414
Cellular Component	GO:0008076	voltage-gated potassium channel complex	KCNMA1	IDA		Human	PMID:7573516
Cellular Component	GO:0008076	voltage-gated potassium channel complex	KCNMA1	IDA		Human	PMID:7877450
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnma1	IGI	MGI:MGI:1913272	Mouse	PMID:12388098
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnma1	IGI	MGI:MGI:1334203	Mouse	PMID:12388098
Biological Process	GO:0007628	adult walking behavior	Kcnma1	IMP	MGI:MGI:3053849	Mouse	PMID:15184377
Biological Process	GO:0007628	adult walking behavior	Kcnma1	IMP	MGI:MGI:3050114	Mouse	PMID:15194823
Biological Process	GO:0007568	aging	Kcnma1	IEP		Rat	PMID:24051206\|RGD:10412028
Biological Process	GO:0097746	blood vessel diameter maintenance	Kcnma1	IDA		Rat	PMID:11157674\|RGD:1581588
Biological Process	GO:0007268	chemical synaptic transmission	Kcnma1	IMP	MGI:MGI:3050114	Mouse	PMID:15194823
Biological Process	GO:0007623	circadian rhythm	Kcnma1	IMP	MGI:MGI:3053849	Mouse	PMID:16845385
Biological Process	GO:0002069	columnar/cuboidal epithelial cell maturation	Kcnma1	IMP	MGI:MGI:3050114	Mouse	PMID:15328414
Biological Process	GO:0060082	eye blink reflex	Kcnma1	IMP	MGI:MGI:3050114	Mouse	PMID:15194823
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	Kcnma1	IMP	MGI:MGI:3050114	Mouse	PMID:15328414
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	Kcnma1	IMP	MGI:MGI:3050114	Mouse	PMID:17074442
Biological Process	GO:0030007	intracellular potassium ion homeostasis	KCNMA1	IDA		Human	PMID:11245614
Biological Process	GO:0045475	locomotor rhythm	Kcnma1	IMP	MGI:MGI:3053849	Mouse	PMID:16845385
Biological Process	GO:0060073	micturition	KCNMA1	IDA		Human	PMID:11641143
Biological Process	GO:0060073	micturition	Kcnma1	IMP	MGI:MGI:3053849	Mouse	PMID:15184377
Biological Process	GO:0045794	negative regulation of cell volume	KCNMA1	IDA		Human	PMID:12388065
Biological Process	GO:0045794	negative regulation of cell volume	Kcnma1	IMP	MGI:MGI:3053849	Mouse	PMID:16873365
Biological Process	GO:1904348	negative regulation of small intestine smooth muscle contraction	Kcnma1	IMP		Rat	PMID:23647678\|RGD:10412032
Biological Process	GO:0050885	neuromuscular process controlling balance	Kcnma1	IMP	MGI:MGI:3053849	Mouse	PMID:15184377
Biological Process	GO:0050885	neuromuscular process controlling balance	Kcnma1	IMP	MGI:MGI:3050114	Mouse	PMID:15194823
Biological Process	GO:0042551	neuron maturation	Kcnma1	IMP	MGI:MGI:3050114	Mouse	PMID:15328414
Biological Process	GO:0019228	neuronal action potential	Kcnma1	IMP	MGI:MGI:3053849	Mouse	PMID:16845385
Biological Process	GO:0043065	positive regulation of apoptotic process	KCNMA1	IMP		Human	PMID:11245614
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Kcnma1	IMP		Rat	PMID:23653329\|RGD:10412031
Biological Process	GO:0006813	potassium ion transport	KCNMA1	IDA		Human	PMID:11245614
Biological Process	GO:0006813	potassium ion transport	KCNMA1	IDA		Human	PMID:12388065
Biological Process	GO:0006813	potassium ion transport	KCNMA1	IDA		Human	PMID:17706472
Biological Process	GO:0006813	potassium ion transport	KCNMA1	IDA		Human	PMID:18458941
Biological Process	GO:0006813	potassium ion transport	KCNMA1	IDA		Human	PMID:7573516
Biological Process	GO:0006813	potassium ion transport	KCNMA1	IDA		Human	PMID:7877450
Biological Process	GO:0006813	potassium ion transport	Kcnma1	IDA		Mouse	PMID:7687074
Biological Process	GO:0006813	potassium ion transport	Kcnma1	IDA		Mouse	PMID:10517674
Biological Process	GO:0032344	regulation of aldosterone metabolic process	Kcnma1	IMP	MGI:MGI:3050114	Mouse	PMID:17122062
Biological Process	GO:0042391	regulation of membrane potential	KCNMA1	IDA		Human	PMID:7877450
Biological Process	GO:0042391	regulation of membrane potential	KCNMA1	IDA		Human	PMID:7993625
Biological Process	GO:0042391	regulation of membrane potential	Kcnma1	IDA		Mouse	PMID:7687074
Biological Process	GO:0042391	regulation of membrane potential	Kcnma1	IMP	MGI:MGI:3050114	Mouse	PMID:16763026
Biological Process	GO:0042391	regulation of membrane potential	Kcnma1	IMP	MGI:MGI:3050114	Mouse	PMID:15194823
Biological Process	GO:0060087	relaxation of vascular associated smooth muscle	Kcnma1	IMP	MGI:MGI:3050114	Mouse	PMID:15867178
Biological Process	GO:0010996	response to auditory stimulus	kcnma1a	IMP	ZFIN:ZDB-MRPHLNO-141009-2	Zfish	PMID:24803460
Biological Process	GO:0010996	response to auditory stimulus	kcnma1b	IMP	ZFIN:ZDB-MRPHLNO-141009-3	Zfish	PMID:24803460
Biological Process	GO:0051592	response to calcium ion	KCNMA1	IDA		Human	PMID:12388065
Biological Process	GO:0051592	response to calcium ion	KCNMA1	IDA		Human	PMID:18458941
Biological Process	GO:0051592	response to calcium ion	Kcnma1	IDA		Rat	PMID:15111404\|RGD:1581585
Biological Process	GO:0034465	response to carbon monoxide	KCNMA1	IDA		Human	PMID:15528406
Biological Process	GO:0034465	response to carbon monoxide	KCNMA1	IMP		Human	PMID:18180950
Biological Process	GO:0031960	response to corticosteroid	Kcnma1	IDA		Rat	PMID:16675526\|RGD:1581581
Biological Process	GO:0043627	response to estrogen	Kcnma1	IDA		Rat	PMID:16102753\|RGD:1581582
Biological Process	GO:0001666	response to hypoxia	KCNMA1	IDA		Human	PMID:15528406
Biological Process	GO:0001666	response to hypoxia	Kcnma1	IDA		Mouse	PMID:16306267
Biological Process	GO:0001666	response to hypoxia	Kcnma1	IDA		Rat	PMID:15528406\|RGD:1581584
Biological Process	GO:0006970	response to osmotic stress	KCNMA1	IDA		Human	PMID:10840032
Biological Process	GO:0006970	response to osmotic stress	KCNMA1	IDA		Human	PMID:12388065
Biological Process	GO:0009268	response to pH	Kcnma1	IDA		Rat	PMID:12719228\|RGD:1581586
Biological Process	GO:0046541	saliva secretion	Kcnma1	IGI	MGI:MGI:1277957	Mouse	PMID:16873365
Biological Process	GO:0007605	sensory perception of sound	Kcnma1	IMP	MGI:MGI:3050114	Mouse	PMID:16763026
Biological Process	GO:0007605	sensory perception of sound	Kcnma1	IMP	MGI:MGI:3050114	Mouse	PMID:15328414
Biological Process	GO:0060083	smooth muscle contraction involved in micturition	KCNMA1	IDA		Human	PMID:11641143
Biological Process	GO:0060083	smooth muscle contraction involved in micturition	Kcnma1	IMP	MGI:MGI:3053849	Mouse	PMID:15827347
Biological Process	GO:0042311	vasodilation	Kcnma1	IMP	MGI:MGI:3050114	Mouse	PMID:15867178
Biological Process	GO:0042311	vasodilation	Kcnma1	IMP		Rat	PMID:23432816\|RGD:10412027

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.