| GO term: | relaxation of vascular smooth muscle |
| Synonym: | vascular smooth muscle relaxation |
| GO id: | GO:0060087 |
| Definition: | A process in which the extent of vascular smooth muscle contraction is reduced. Vascular smooth muscle relaxation is mediated via a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity. |
| Number of paths to term: | 36 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
biological_processbiological regulationregulation of biological processnegative regulation of biological processnegative regulation of multicellular organismal processnegative regulation of muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processbiological regulationregulation of biological processregulation of multicellular organismal processnegative regulation of multicellular organismal processnegative regulation of muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processbiological regulationregulation of biological processregulation of multicellular organismal processregulation of system processregulation of muscle system processregulation of muscle contractionnegative regulation of muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processbiological regulationregulation of biological processregulation of multicellular organismal processregulation of system processregulation of muscle system processregulation of muscle contractionregulation of smooth muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processbiological regulationregulation of biological qualityregulation of anatomical structure sizeregulation of tube sizeregulation of blood vessel sizevasodilationnegative regulation of vasodilationpositive regulation of vasodilationregulation of vasodilation +relaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)vasodilation by acetylcholine involved in regulation of systemic arterial blood pressurevasodilation by angiotensin involved in regulation of systemic arterial blood pressurevasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressurevasodilation involved in acute inflammatory responsevasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressurebiological_processmulticellular organismal processsingle-multicellular organism processnegative regulation of multicellular organismal processnegative regulation of muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processmulticellular organismal processsingle-multicellular organism processsystem processcirculatory system processblood circulationregulation of blood vessel sizevasodilationnegative regulation of vasodilationpositive regulation of vasodilationregulation of vasodilation +relaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)vasodilation by acetylcholine involved in regulation of systemic arterial blood pressurevasodilation by angiotensin involved in regulation of systemic arterial blood pressurevasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressurevasodilation involved in acute inflammatory responsevasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressurebiological_processmulticellular organismal processsingle-multicellular organism processsystem processcirculatory system processvascular process in circulatory systemregulation of blood vessel sizevasodilationnegative regulation of vasodilationpositive regulation of vasodilationregulation of vasodilation +relaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)vasodilation by acetylcholine involved in regulation of systemic arterial blood pressurevasodilation by angiotensin involved in regulation of systemic arterial blood pressurevasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressurevasodilation involved in acute inflammatory responsevasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressurebiological_processmulticellular organismal processsingle-multicellular organism processsystem processmuscle system processmuscle contractionnegative regulation of muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processmulticellular organismal processsingle-multicellular organism processsystem processmuscle system processmuscle contractionregulation of muscle contractionnegative regulation of muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processmulticellular organismal processsingle-multicellular organism processsystem processmuscle system processmuscle contractionregulation of muscle contractionregulation of smooth muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processmulticellular organismal processsingle-multicellular organism processsystem processmuscle system processmuscle contractionsmooth muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processmulticellular organismal processsingle-multicellular organism processsystem processmuscle system processmuscle contractionsmooth muscle contractionregulation of smooth muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processmulticellular organismal processsingle-multicellular organism processsystem processmuscle system processregulation of muscle system processregulation of muscle contractionnegative regulation of muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processmulticellular organismal processsingle-multicellular organism processsystem processmuscle system processregulation of muscle system processregulation of muscle contractionregulation of smooth muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processmulticellular organismal processsingle-multicellular organism processsystem processmuscle system processrelaxation of musclerelaxation of smooth musclenegative regulation of relaxation of smooth muscle +positive regulation of relaxation of smooth muscle +regulation of relaxation of smooth muscle +relaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletuterine smooth muscle relaxation +biological_processmulticellular organismal processsingle-multicellular organism processsystem processregulation of system processregulation of muscle system processregulation of muscle contractionnegative regulation of muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processmulticellular organismal processsingle-multicellular organism processsystem processregulation of system processregulation of muscle system processregulation of muscle contractionregulation of smooth muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processnegative regulation of biological processnegative regulation of multicellular organismal processnegative regulation of muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processregulation of biological processnegative regulation of biological processnegative regulation of multicellular organismal processnegative regulation of muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processregulation of biological processregulation of multicellular organismal processnegative regulation of multicellular organismal processnegative regulation of muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processregulation of biological processregulation of multicellular organismal processregulation of system processregulation of muscle system processregulation of muscle contractionnegative regulation of muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processregulation of biological processregulation of multicellular organismal processregulation of system processregulation of muscle system processregulation of muscle contractionregulation of smooth muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processsingle-organism processsingle-multicellular organism processnegative regulation of multicellular organismal processnegative regulation of muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processsingle-organism processsingle-multicellular organism processsystem processcirculatory system processblood circulationregulation of blood vessel sizevasodilationnegative regulation of vasodilationpositive regulation of vasodilationregulation of vasodilation +relaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)vasodilation by acetylcholine involved in regulation of systemic arterial blood pressurevasodilation by angiotensin involved in regulation of systemic arterial blood pressurevasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressurevasodilation involved in acute inflammatory responsevasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressurebiological_processsingle-organism processsingle-multicellular organism processsystem processcirculatory system processvascular process in circulatory systemregulation of blood vessel sizevasodilationnegative regulation of vasodilationpositive regulation of vasodilationregulation of vasodilation +relaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)vasodilation by acetylcholine involved in regulation of systemic arterial blood pressurevasodilation by angiotensin involved in regulation of systemic arterial blood pressurevasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressurevasodilation involved in acute inflammatory responsevasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressurebiological_processsingle-organism processsingle-multicellular organism processsystem processmuscle system processmuscle contractionnegative regulation of muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processsingle-organism processsingle-multicellular organism processsystem processmuscle system processmuscle contractionregulation of muscle contractionnegative regulation of muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processsingle-organism processsingle-multicellular organism processsystem processmuscle system processmuscle contractionregulation of muscle contractionregulation of smooth muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processsingle-organism processsingle-multicellular organism processsystem processmuscle system processmuscle contractionsmooth muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processsingle-organism processsingle-multicellular organism processsystem processmuscle system processmuscle contractionsmooth muscle contractionregulation of smooth muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processsingle-organism processsingle-multicellular organism processsystem processmuscle system processregulation of muscle system processregulation of muscle contractionnegative regulation of muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processsingle-organism processsingle-multicellular organism processsystem processmuscle system processregulation of muscle system processregulation of muscle contractionregulation of smooth muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processsingle-organism processsingle-multicellular organism processsystem processmuscle system processrelaxation of musclerelaxation of smooth musclenegative regulation of relaxation of smooth muscle +positive regulation of relaxation of smooth muscle +regulation of relaxation of smooth muscle +relaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletuterine smooth muscle relaxation +biological_processsingle-organism processsingle-multicellular organism processsystem processregulation of system processregulation of muscle system processregulation of muscle contractionnegative regulation of muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletbiological_processsingle-organism processsingle-multicellular organism processsystem processregulation of system processregulation of muscle system processregulation of muscle contractionregulation of smooth muscle contractionnegative regulation of smooth muscle contractionnegative regulation of hindgut contractionnegative regulation of uterine smooth muscle contractionrelaxation of vascular smooth muscle [GO:0060087] (6 genes, 6 annotations)smooth muscle relaxation of the bladder outletMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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