Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HSF2
  • Mouse genes Hsf2
  • Rat genes Hsf2
  • Zfish genes hsf2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hsf2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Hsf2	IDA		Mouse	PMID:11032181
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	HSF2	IDA		Human	PMID:10561509
Molecular Function	GO:0042802	identical protein binding	Hsf2	IPI	PR:P38533	Mouse	PMID:18755693
Molecular Function	GO:0005515	protein binding	HSF2	IPI	UniProtKB:Q00613	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	HSF2	IPI	UniProtKB:P06753	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HSF2	IPI	UniProtKB:P37198	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HSF2	IPI	UniProtKB:P61964	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HSF2	IPI	UniProtKB:Q5VU62	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HSF2	IPI	UniProtKB:P06753	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	HSF2	IPI	UniProtKB:Q00613	Human	PMID:26727490
Molecular Function	GO:0005515	protein binding	HSF2	IPI	UniProtKB:P06753	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	HSF2	IPI	UniProtKB:P37198	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	HSF2	IPI	UniProtKB:P61964	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	HSF2	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HSF2	IPI	UniProtKB:P06753	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HSF2	IPI	UniProtKB:P61964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HSF2	IPI	UniProtKB:Q5JR59-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HSF2	IPI	UniProtKB:Q8TAP6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HSF2	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HSF2	IPI	UniProtKB:Q9Y315	Human	PMID:32296183
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	HSF2	IDA		Human	PMID:8972228
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Hsf2	IDA		Mouse	PMID:18434628
Molecular Function	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	HSF2	IDA		Human	PMID:10561509
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	HSF2	IDA		Human	PMID:10561509
Molecular Function	GO:0043565	sequence-specific DNA binding	Hsf2	IDA		Mouse	PMID:18755693
Molecular Function	GO:0043565	sequence-specific DNA binding	hsf2	IDA		Zfish	PMID:22528049
Molecular Function	GO:0043565	sequence-specific DNA binding	hsf2	IDA		Zfish	PMID:16938384
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	HSF2	IDA		Human	PMID:28473536
Cellular Component	GO:0005737	cytoplasm	Hsf2	IDA		Mouse	PMID:11032181
Cellular Component	GO:0005654	nucleoplasm	HSF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Hsf2	IDA		Mouse	PMID:11032181
Cellular Component	GO:0005634	nucleus	Hsf2	IDA		Mouse	PMID:18434628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	HSF2	IDA		Human	PMID:10561509
Biological Process	GO:0007283	spermatogenesis	Hsf2	IMP	MGI:MGI:2664942	Mouse	PMID:14994269

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern