Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GNA11
  • Mouse genes Gna11
  • Rat genes Gna11
  • Zfish genes gna11a,gna11b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gna11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity	Gna11	IDA		Rat	PMID:21812758|RGD:10448949
Molecular Function	GO:0003925	G protein activity	Gna11	IMP		Mouse	PMID:26075576
Molecular Function	GO:0016004	phospholipase activator activity	Gna11	IMP		Mouse	PMID:26075576
Molecular Function	GO:0005515	protein binding	GNA11	IPI	UniProtKB:Q8NE09	Human	PMID:18703424
Molecular Function	GO:0005515	protein binding	Gna11	IPI	UniProtKB:Q8BFU1	Mouse	MGI:MGI:6791231|PMID:26208885
Molecular Function	GO:0044877	protein-containing complex binding	Gna11	IPI	RGD:61276|RGD:620770	Rat	PMID:20548297|RGD:5491170
Cellular Component	GO:0005737	cytoplasm	GNA11	IDA		Human	PMID:18703424
Cellular Component	GO:0005829	cytosol	Gna11	IDA		Rat	PMID:14534355|RGD:1601365
Cellular Component	GO:0005829	cytosol	Gna11	IDA		Rat	PMID:15175423|RGD:5133684
Cellular Component	GO:0070062	extracellular exosome	GNA11	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	GNA11	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	GNA11	HDA		Human	PMID:23533145
Cellular Component	GO:0005834	heterotrimeric G-protein complex	Gna11	IDA		Rat	PMID:21812758|RGD:10448949
Cellular Component	GO:0005765	lysosomal membrane	GNA11	HDA		Human	PMID:17897319
Cellular Component	GO:0005886	plasma membrane	Gna11	IDA		Mouse	PMID:9765251
Cellular Component	GO:0005886	plasma membrane	Gna11	IGI	MGI:MGI:95766	Mouse	PMID:20440069
Cellular Component	GO:0005886	plasma membrane	Gna11	IDA		Rat	PMID:14534355|RGD:1601365
Cellular Component	GO:0005886	plasma membrane	Gna11	IDA		Rat	PMID:15175423|RGD:5133684
Biological Process	GO:0001508	action potential	Gna11	IDA		Mouse	PMID:10818132
Biological Process	GO:0071467	cellular response to pH	Gna11	IMP		Mouse	PMID:22733973
Biological Process	GO:1904888	cranial skeletal system development	Gna11	IGI	MGI:MGI:95776	Mouse	PMID:18199583
Biological Process	GO:1904888	cranial skeletal system development	Gna11	IGI	MGI:MGI:95766	Mouse	PMID:18199583
Biological Process	GO:0048066	developmental pigmentation	Gna11	IMP	MGI:MGI:2151589	Mouse	PMID:15322542
Biological Process	GO:0086100	endothelin receptor signaling pathway	Gna11	IGI	MGI:MGI:95776	Mouse	PMID:18199583
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Gna11	IMP	MGI:MGI:2151589	Mouse	PMID:9687499
Biological Process	GO:0007507	heart development	Gna11	IMP	MGI:MGI:2151589	Mouse	PMID:9687499
Biological Process	GO:0099105	ion channel modulating, G protein-coupled receptor signaling pathway	Gna11	IGI	MGI:MGI:95776	Mouse	PMID:20440069
Biological Process	GO:0099105	ion channel modulating, G protein-coupled receptor signaling pathway	Gna11	IMP		Mouse	PMID:26075576
Biological Process	GO:1990806	ligand-gated ion channel signaling pathway	Gna11	IGI	MGI:MGI:95776	Mouse	PMID:20440069
Biological Process	GO:1990806	ligand-gated ion channel signaling pathway	Gna11	IMP		Mouse	PMID:26075576
Biological Process	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway	Gna11	IGI	MGI:MGI:95776	Mouse	PMID:17194762
Biological Process	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway	Gna11	IGI	MGI:MGI:99578	Mouse	PMID:17194762
Biological Process	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway	Gna11	IGI	MGI:MGI:94924	Mouse	PMID:17194762
Biological Process	GO:0007207	phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway	Gna11	IGI	MGI:MGI:95776	Mouse	PMID:20440069
Biological Process	GO:0007207	phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway	Gna11	IGI	MGI:MGI:95766	Mouse	PMID:20440069
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	Gna11	IGI	MGI:MGI:95776	Mouse	PMID:20440069
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	Gna11	IMP		Mouse	PMID:26075576
Biological Process	GO:0032024	positive regulation of insulin secretion	Gna11	IGI	MGI:MGI:95776	Mouse	PMID:20440069
Biological Process	GO:0032024	positive regulation of insulin secretion	Gna11	IGI	MGI:MGI:95766	Mouse	PMID:20440069
Biological Process	GO:0032024	positive regulation of insulin secretion	Gna11	IMP		Mouse	PMID:26075576
Biological Process	GO:0008217	regulation of blood pressure	Gna11	IGI	MGI:MGI:95776	Mouse	PMID:26531127
Biological Process	GO:0045634	regulation of melanocyte differentiation	Gna11	IMP	MGI:MGI:2682213	Mouse	PMID:15322542
Biological Process	GO:0001501	skeletal system development	Gna11	IMP	MGI:MGI:2151589	Mouse	PMID:9687499

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern