| GO term: | heterotrimeric G-protein complex |
| Synonym: | heterotrimeric G-protein GTPase activity |
| Synonym: | heterotrimeric G-protein GTPase, alpha-subunit |
| Synonym: | heterotrimeric G-protein GTPase, beta-subunit |
| Synonym: | heterotrimeric G-protein GTPase, gamma-subunit |
| GO id: | GO:0005834 |
| Definition: | Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G-protein coupled receptors to an effector protein. |
| Comments | See also the molecular function term 'G-protein coupled receptor activity ; GO:0004930'. |
| Number of paths to term: | 25 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 06/05/2013 MGI 5.13 |
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