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Gna11
Gene Detail
Symbol

Name
ID
Gna11
guanine nucleotide binding protein, alpha 11
MGI:95766
Synonyms
Dsk7
Feature Type
protein coding gene
Genetic Map
Chromosome 10
39.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr10:81528724-81545190 bp, - strand
From VEGA annotation of GRCm38

  16467 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20474  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Gna11

Human
homologs
Human Homolog GNA11, guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
NCBI Gene ID 2767
neXtProt AC  NX_P29992
Human Synonyms  FBH, FBH2, FHH2, GNA-11, HHC2, HYPOC2
Human Chr (Location)  19p13.3; chr19:3094410-3124002 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Chemically induced (ENU)(1) Gene trapped(6) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice deficient for this gene do not exhibit any detectable abnormalities.
 
Interactions
Gna11 interacts with 211 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (8 records)
Data Summary: Results (45)    Tissues (27)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 24
Western blot 6
RT-PCR 15
cDNA source data(12)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(25) Genomic(8) cDNA(12) Primer pair(4) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000030287 (Evidence)
Ensembl Gene ModelENSMUSG00000034781 (Evidence)
Entrez Gene14672 (Evidence)
DFCITC1575884
DoTSDT.110616071, DT.532777, DT.94189415
NIA Mouse Gene IndexU052056
Consensus CDS ProjectCCDS24061.1
International Mouse Knockout Project StatusGna11
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030287 VEGA Gene Model | MGI Sequence Detail 16467 C57BL/6J ±  kb
transcript OTTMUST00000074975 VEGA | MGI Sequence Detail 3414 Not Applicable 
polypeptide OTTMUSP00000039227 VEGA | MGI Sequence Detail 359 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(2) UniProt(4)
Polymorphisms
RFLP(1) : SNPs within 2kb(44 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000654 G-protein alpha subunit, group Q
InterPro IPR011025 G protein alpha subunit, helical insertion
InterPro IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000008080 guanine nucleotide-binding protein subunit alpha-11
References
(Earliest) J:30942 Sewell JL, et al., Sequences of the bovine and yeast ADP-ribosylation factor and comparison to other GTP-binding proteins. Proc Natl Acad Sci U S A. 1988 Jul;85(13):4620-4
(Latest) J:206486 Rusu L, et al., G protein-dependent basal and evoked endothelial cell vWF secretion. Blood. 2014 Jan 16;123(3):442-50
All references(89)
Other
accession IDs
MGD-MRK-10175, MGI:2450689

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory