Gna11 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gna11
guanine nucleotide binding protein, alpha 11
MGI:95766

33 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gna11^em1Mman/Gna11⁺ C57BL/6NCrl-Gna11^em1Mman	decreased bone mineral density	J:280180
	decreased circulating calcium level	J:280180
	decreased circulating parathyroid hormone level	J:280180
	increased ear pigmentation	J:280180
	increased tail pigmentation	J:280180
	preweaning lethality, incomplete penetrance	J:280180
Gna11^em1Mman/Gna11^em1Mman C57BL/6NCrl-Gna11^em1Mman	decreased bone mineral density	J:280180
	decreased bone trabecula number	J:280180
	decreased circulating calcium level	J:280180
	decreased circulating parathyroid hormone level	J:280180
	decreased compact bone thickness	J:280180
	increased bone trabecular spacing	J:280180
	increased circulating phosphate level	J:280180
	increased ear pigmentation	J:280180
	increased tail pigmentation	J:280180
	preweaning lethality, incomplete penetrance	J:280180
Gna11^Mhdadsk7/Gna11⁺ C3HeB/FeJ-Gna11^Mhdadsk7/Ieg	darkened coat color	J:81301
	hyperpigmentation	J:81301
	increased ear pigmentation	J:81301
	increased foot pad pigmentation	J:81301
	increased tail pigmentation	J:81301
Gna11^Mhdadsk7/Gna11^Mhdadsk7 involves: C3HeB/FeJ * C57BL/6J	darkened coat color	J:81301
	hyperpigmentation	J:81301
	increased ear pigmentation	J:81301
	increased foot pad pigmentation	J:81301
	increased tail pigmentation	J:81301
Gna11^{tm1a(EUCOMM)Wtsi}/Gna11^{tm1a(EUCOMM)Wtsi} C57BL/6N-Gna11^{tm1a(EUCOMM)Wtsi}/Cnrm	abnormal behavior	J:165965
	abnormal bone mineralization	J:165965
	decreased body weight	J:165965
	decreased bone mineral density	J:165965
	decreased circulating amylase level	J:165965
	decreased circulating phosphate level	J:165965
	decreased circulating total protein level	J:165965
	decreased circulating triglyceride level	J:165965
	decreased hemoglobin content	J:165965
	increased circulating calcium level	J:165965
Gna11^{tm1b(EUCOMM)Wtsi}/Gna11^{tm1b(EUCOMM)Wtsi} C57BL/6N-Gna11^{tm1b(EUCOMM)Wtsi}/H	decreased erythrocyte cell number	J:211773
	decreased hematocrit	J:211773
	decreased hemoglobin content	J:211773
	decreased mean corpuscular volume	J:211773
	increased red blood cell distribution width	J:211773
	thrombocytopenia	J:211773
	vertebral fusion	J:211773
Gna11^tm1Soff/Gna11^tm1Soff involves: 129S7/SvEvBrd	decreased susceptibility to type I hypersensitivity reaction	J:146132
	hepatic steatosis	J:172091
	increased circulating triglyceride level	J:172091
	increased liver triglyceride level	J:172091
	normal nervous system phenotype	J:70180
Gna11^tm1Soff/Gna11^tm1Soff involves: 129S7/SvEvBrd * C57BL/6	normal nervous system phenotype	J:126972

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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