Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FOXI1
  • Mouse genes Foxi1
  • Rat genes Foxi1
  • Zfish genes foxi1,foxi3a,foxi3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Foxi1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	FOXI1	IDA		Human	PMID:19214237
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Foxi1	IDA		Mouse	MGI:MGI:3689809|PMID:16159312
Molecular Function	GO:0003700	DNA-binding transcription factor activity	FOXI1	IDA		Human	PMID:19214237
Molecular Function	GO:0003700	DNA-binding transcription factor activity	foxi1	IDA		Zfish	PMID:18086703
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	FOXI1	IDA		Human	PMID:19214237
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Foxi1	IDA		Mouse	MGI:MGI:3689809|PMID:16159312
Molecular Function	GO:0043565	sequence-specific DNA binding	Foxi1	IDA		Mouse	MGI:MGI:3689809|PMID:16159312
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	FOXI1	IDA		Human	PMID:28473536
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Foxi1	IDA		Mouse	PMID:7958446
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	FOXI1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	FOXI1	IDA		Human	GO_REF:0000052
Biological Process	GO:0061550	cranial ganglion development	foxi1	IMP	ZFIN:ZDB-GENO-980520-29	Zfish	PMID:12736211
Biological Process	GO:0071696	ectodermal placode development	foxi1	IMP	ZFIN:ZDB-MRPHLNO-061106-7	Zfish	PMID:25044691
Biological Process	GO:0060788	ectodermal placode formation	foxi1	IGI	ZFIN:ZDB-MRPHLNO-061106-7,ZFIN:ZDB-MRPHLNO-080220-1,ZFIN:ZDB-MRPHLNO-080226-1,ZFIN:ZDB-MRPHLNO-101026-8	Zfish	PMID:20885782
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	foxi1	IMP	ZFIN:ZDB-GENO-021125-1	Zfish	PMID:12702667
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	foxi1	IMP	ZFIN:ZDB-GENO-980520-29	Zfish	PMID:10191060
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	foxi1	IMP	ZFIN:ZDB-GENO-070430-4	Zfish	PMID:12538519
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	foxi1	IMP	ZFIN:ZDB-MRPHLNO-061106-7	Zfish	PMID:12538519
Biological Process	GO:0009913	epidermal cell differentiation	foxi3a	IMP	ZFIN:ZDB-MRPHLNO-070321-6	Zfish	PMID:16946087
Biological Process	GO:0009957	epidermal cell fate specification	foxi1	IMP	ZFIN:ZDB-MRPHLNO-090520-6	Zfish	PMID:19268451
Biological Process	GO:0009957	epidermal cell fate specification	foxi3a	IDA		Zfish	PMID:17375188
Biological Process	GO:0009957	epidermal cell fate specification	foxi3a	IMP	ZFIN:ZDB-MRPHLNO-070321-5	Zfish	PMID:19268451
Biological Process	GO:0009957	epidermal cell fate specification	foxi3a	IMP	ZFIN:ZDB-MRPHLNO-070618-6	Zfish	PMID:17375188
Biological Process	GO:0009957	epidermal cell fate specification	foxi3a	IGI	ZFIN:ZDB-MRPHLNO-070618-6,ZFIN:ZDB-MRPHLNO-070620-2	Zfish	PMID:23924428
Biological Process	GO:0009957	epidermal cell fate specification	foxi3a	IMP	ZFIN:ZDB-MRPHLNO-070618-5	Zfish	PMID:17375188
Biological Process	GO:0009957	epidermal cell fate specification	foxi3b	IDA		Zfish	PMID:17375188
Biological Process	GO:0009957	epidermal cell fate specification	foxi3b	IMP	ZFIN:ZDB-MRPHLNO-070620-1	Zfish	PMID:17375188
Biological Process	GO:0009957	epidermal cell fate specification	foxi3b	IMP	ZFIN:ZDB-MRPHLNO-070620-2	Zfish	PMID:17375188
Biological Process	GO:0009957	epidermal cell fate specification	foxi3b	IGI	ZFIN:ZDB-MRPHLNO-070618-6,ZFIN:ZDB-MRPHLNO-070620-2	Zfish	PMID:23924428
Biological Process	GO:0042472	inner ear morphogenesis	Foxi1	IMP	MGI:MGI:2448634	Mouse	PMID:12642503
Biological Process	GO:0062236	ionocyte differentiation	foxi3a	IMP	ZFIN:ZDB-MRPHLNO-101108-4	Zfish	PMID:17555741
Biological Process	GO:0062236	ionocyte differentiation	foxi3b	IMP	ZFIN:ZDB-MRPHLNO-101108-3	Zfish	PMID:17555741
Biological Process	GO:0048890	lateral line ganglion development	foxi1	IMP	ZFIN:ZDB-GENO-980520-29	Zfish	PMID:12736211
Biological Process	GO:0050891	multicellular organismal-level water homeostasis	foxi3a	IMP	ZFIN:ZDB-MRPHLNO-101108-4	Zfish	PMID:19757382
Biological Process	GO:0014032	neural crest cell development	foxi1	IMP	ZFIN:ZDB-GENO-980520-29	Zfish	PMID:10191060
Biological Process	GO:0001755	neural crest cell migration	foxi1	IMP	ZFIN:ZDB-GENO-021125-1	Zfish	PMID:12702667
Biological Process	GO:0048666	neuron development	foxi1	IMP	ZFIN:ZDB-GENO-980520-29	Zfish	PMID:10191060
Biological Process	GO:0043049	otic placode formation	foxi1	IGI	ZFIN:ZDB-MRPHLNO-041109-1,ZFIN:ZDB-MRPHLNO-061106-7	Zfish	PMID:23078916
Biological Process	GO:0043049	otic placode formation	foxi1	IMP	ZFIN:ZDB-GENO-030617-1	Zfish	PMID:15188428
Biological Process	GO:0043049	otic placode formation	foxi1	IGI	ZFIN:ZDB-MRPHLNO-061106-7,ZFIN:ZDB-MRPHLNO-101026-8	Zfish	PMID:23078916
Biological Process	GO:0043049	otic placode formation	foxi1	IGI	ZFIN:ZDB-GENO-980202-981	Zfish	PMID:15459102
Biological Process	GO:0043049	otic placode formation	foxi1	IGI	ZFIN:ZDB-GENE-980526-280,ZFIN:ZDB-GENE-990415-50	Zfish	PMID:15188428
Biological Process	GO:0043049	otic placode formation	foxi1	IMP		Zfish	PMID:9007247
Biological Process	GO:0043049	otic placode formation	foxi1	IMP	ZFIN:ZDB-MRPHLNO-050209-1	Zfish	PMID:15604103
Biological Process	GO:0043049	otic placode formation	foxi1	IMP	ZFIN:ZDB-GENO-030617-1	Zfish	PMID:15459102
Biological Process	GO:0043049	otic placode formation	foxi1	IGI	ZFIN:ZDB-GENE-980526-280	Zfish	PMID:15459102
Biological Process	GO:0071599	otic vesicle development	foxi1	IMP	ZFIN:ZDB-GENO-021125-1	Zfish	PMID:12702667
Biological Process	GO:0071599	otic vesicle development	foxi1	IMP	ZFIN:ZDB-GENO-070430-4	Zfish	PMID:12538519
Biological Process	GO:0071599	otic vesicle development	foxi1	IMP	ZFIN:ZDB-MRPHLNO-061106-7	Zfish	PMID:12538519
Biological Process	GO:0030916	otic vesicle formation	foxi1	IGI	ZFIN:ZDB-GENE-980526-280,ZFIN:ZDB-GENE-990415-50	Zfish	PMID:15188428
Biological Process	GO:0030916	otic vesicle formation	foxi1	IGI	ZFIN:ZDB-GENE-980526-280	Zfish	PMID:15188428
Biological Process	GO:0030916	otic vesicle formation	foxi1	IGI	ZFIN:ZDB-GENO-980202-822	Zfish	PMID:15188428
Biological Process	GO:0030916	otic vesicle formation	foxi1	IMP	ZFIN:ZDB-GENO-030617-1	Zfish	PMID:15188428
Biological Process	GO:0030916	otic vesicle formation	foxi1	IGI	ZFIN:ZDB-GENE-990415-72	Zfish	PMID:15188428
Biological Process	GO:0030916	otic vesicle formation	foxi1	IMP	ZFIN:ZDB-MRPHLNO-061106-7	Zfish	PMID:17239227
Biological Process	GO:0030916	otic vesicle formation	foxi1	IGI	ZFIN:ZDB-MRPHLNO-041109-1,ZFIN:ZDB-MRPHLNO-061106-7	Zfish	PMID:17239227
Biological Process	GO:0071600	otic vesicle morphogenesis	foxi1	IMP	ZFIN:ZDB-GENO-070430-4	Zfish	PMID:23571216
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Foxi1	IDA		Mouse	MGI:MGI:3689809|PMID:16159312
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	FOXI1	IDA		Human	PMID:19214237
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Foxi1	IDA		Mouse	MGI:MGI:3689809|PMID:16159312
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Foxi1	IDA		Mouse	PMID:7958446
Biological Process	GO:0006355	regulation of DNA-templated transcription	foxi1	IDA		Zfish	PMID:18086703

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern