Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ETV6
  • Mouse genes Etv6
  • Rat genes Etv6
  • Zfish genes etv6,etv7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Etv6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Etv6	IDA		Mouse	PMID:12527908
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Etv6	IDA		Mouse	MGI:MGI:3721210|PMID:17606295
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Etv6	IDA		Mouse	PMID:12527908
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ETV6	IDA		Human	PMID:10514502
Molecular Function	GO:0005515	protein binding	ETV6	IPI	UniProtKB:Q9UKV0-3	Human	PMID:12590135
Molecular Function	GO:0005515	protein binding	ETV6	IPI	UniProtKB:Q96HA8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ETV6	IPI	UniProtKB:Q9BXS5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ETV6	IPI	UniProtKB:A0A0S2Z4M1	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	ETV6	IPI	UniProtKB:Q13526	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ETV6	IPI	UniProtKB:Q16236	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	Etv6	IPI	PR:Q60520	Mouse	PMID:12527908
Molecular Function	GO:0019904	protein domain specific binding	ETV6	IPI	UniProtKB:Q9Y468	Human	PMID:12588862
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Etv6	IDA		Mouse	MGI:MGI:3721210|PMID:17606295
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ETV6	IDA		Human	PMID:9018121
Cellular Component	GO:0005829	cytosol	ETV6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	ETV6	IDA		Human	GO_REF:0000052
Biological Process	GO:0030154	cell differentiation	Etv6	IDA		Mouse	PMID:12527908
Biological Process	GO:0035162	embryonic hemopoiesis	etv6	IMP	ZFIN:ZDB-MRPHLNO-150225-5	Zfish	PMID:25281506
Biological Process	GO:0035162	embryonic hemopoiesis	etv6	IMP	ZFIN:ZDB-MRPHLNO-150226-1	Zfish	PMID:25281506
Biological Process	GO:0048821	erythrocyte development	etv7	IMP	ZFIN:ZDB-MRPHLNO-140612-2	Zfish	PMID:24357328
Biological Process	GO:0048821	erythrocyte development	etv7	IMP	ZFIN:ZDB-MRPHLNO-140612-3	Zfish	PMID:24357328
Biological Process	GO:0071425	hematopoietic stem cell proliferation	ETV6	IMP		Human	PMID:25581430
Biological Process	GO:0097152	mesenchymal cell apoptotic process	Etv6	IMP	MGI:MGI:2177950	Mouse	PMID:9250681
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ETV6	IDA		Human	PMID:10514502
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ETV6	IMP		Human	PMID:10514502
Biological Process	GO:0022008	neurogenesis	Etv6	IMP	MGI:MGI:2177950	Mouse	PMID:9250681
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Etv6	IDA		Mouse	MGI:MGI:3721210|PMID:17606295
Biological Process	GO:0006355	regulation of DNA-templated transcription	Etv6	IDA		Mouse	PMID:12527908
Biological Process	GO:0007296	vitellogenesis	Etv6	IMP	MGI:MGI:2177950	Mouse	PMID:9250681

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern