Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ERO1A
  • Mouse genes Ero1a
  • Rat genes Ero1a
  • Zfish genes ero1a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ero1a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016491	oxidoreductase activity	ERO1A	IDA		Human	PMID:11707400
Molecular Function	GO:0016491	oxidoreductase activity	ERO1A	IDA		Human	PMID:29858230
Molecular Function	GO:0016491	oxidoreductase activity	Ero1a	IDA		Mouse	PMID:15601821
Molecular Function	GO:0005515	protein binding	ERO1A	IPI	UniProtKB:P30101	Human	PMID:17170699
Molecular Function	GO:0005515	protein binding	ERO1A	IPI	UniProtKB:P07237	Human	PMID:20802462
Molecular Function	GO:0005515	protein binding	ERO1A	IPI	UniProtKB:P30101	Human	PMID:20802462
Molecular Function	GO:0005515	protein binding	ERO1A	IPI	UniProtKB:Q92624	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ERO1A	IPI	UniProtKB:Q9BS26	Human	PMID:29858230
Molecular Function	GO:0005515	protein binding	ERO1A	IPI	UniProtKB:Q969G2	Human	PMID:32296183
Molecular Function	GO:0015035	protein-disulfide reductase activity	Ero1a	IDA		Mouse	PMID:20308425
Cellular Component	GO:0030425	dendrite	Ero1a	IDA		Rat	PMID:12694393|RGD:632668
Cellular Component	GO:0005783	endoplasmic reticulum	ERO1A	IDA		Human	PMID:10671517
Cellular Component	GO:0005783	endoplasmic reticulum	ERO1A	IDA		Human	PMID:29858230
Cellular Component	GO:0005615	extracellular space	ERO1A	IDA		Human	PMID:29858230
Cellular Component	GO:0005796	Golgi lumen	ERO1A	IDA		Human	PMID:29858230
Cellular Component	GO:0016020	membrane	ERO1A	HDA		Human	PMID:19946888
Biological Process	GO:0050873	brown fat cell differentiation	Ero1a	IDA		Mouse	PMID:18492766
Biological Process	GO:0045454	cell redox homeostasis	ERO1A	IMP		Human	PMID:29858230
Biological Process	GO:0045454	cell redox homeostasis	Ero1a	IGI	MGI:MGI:1859815	Mouse	PMID:23589496
Biological Process	GO:0045454	cell redox homeostasis	Ero1a	IGI	MGI:MGI:1914725	Mouse	PMID:23589496
Biological Process	GO:0071456	cellular response to hypoxia	Ero1a	IEP		Rat	PMID:12752442|RGD:10401130
Biological Process	GO:0051085	chaperone cofactor-dependent protein refolding	ERO1A	IDA		Human	PMID:11707400
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	Ero1a	IDA		Mouse	PMID:15601821
Biological Process	GO:0030198	extracellular matrix organization	Ero1a	IGI	MGI:MGI:1859815	Mouse	PMID:22981861
Biological Process	GO:0030198	extracellular matrix organization	Ero1a	IGI	MGI:MGI:1914725	Mouse	PMID:22981861
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	Ero1a	IMP		Mouse	MGI:MGI:4366390|PMID:19752026
Biological Process	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	Ero1a	IGI	MGI:MGI:1914725	Mouse	PMID:22981861
Biological Process	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	Ero1a	IGI	MGI:MGI:1859815	Mouse	PMID:22981861
Biological Process	GO:0006457	protein folding	ERO1A	IMP		Human	PMID:29858230
Biological Process	GO:0006457	protein folding	Ero1a	IDA		Mouse	PMID:15601821
Biological Process	GO:0022417	protein maturation by protein folding	Ero1a	IGI	MGI:MGI:1859815	Mouse	PMID:22981861
Biological Process	GO:0022417	protein maturation by protein folding	Ero1a	IGI	MGI:MGI:1914725	Mouse	PMID:22981861
Biological Process	GO:0051209	release of sequestered calcium ion into cytosol	Ero1a	IMP		Mouse	MGI:MGI:4366390|PMID:19752026
Biological Process	GO:0034976	response to endoplasmic reticulum stress	Ero1a	IDA		Mouse	MGI:MGI:4366390|PMID:19752026
Biological Process	GO:0006979	response to oxidative stress	Ero1a	IDA		Mouse	PMID:25452428

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern