Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ECT2
  • Mouse genes Ect2
  • Rat genes Ect2
  • Zfish genes ect2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ect2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	ECT2	IMP		Human	PMID:15642749
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ECT2	IDA		Human	PMID:15254234
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ECT2	IDA		Human	PMID:15545273
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:Q04759	Human	PMID:15254234
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:Q8TEW0	Human	PMID:15254234
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:Q9BYG5	Human	PMID:15254234
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:Q9H0H5	Human	PMID:16103226
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:Q9H0H5	Human	PMID:16129829
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:Q02241	Human	PMID:16236794
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:Q9H0H5	Human	PMID:16236794
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:Q14511	Human	PMID:16394104
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:Q99569	Human	PMID:17115030
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:P16333	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:Q9H0H5	Human	PMID:18201571
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:Q9H0H5	Human	PMID:18511905
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:B2RX88	Human	PMID:19129481
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:Q02241	Human	PMID:19468300
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:Q9H0H5	Human	PMID:19468300
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:Q9H0H5	Human	PMID:19468302
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:P41743	Human	PMID:19617897
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:Q9NPB6	Human	PMID:19617897
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:O00444	Human	PMID:20348415
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:P12830	Human	PMID:22750944
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:P35221	Human	PMID:22750944
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:Q02241	Human	PMID:22750944
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:Q9H0H5	Human	PMID:22750944
Molecular Function	GO:0005515	protein binding	ECT2	IPI	UniProtKB:Q9H0H5	Human	PMID:25068414
Molecular Function	GO:0005515	protein binding	Ect2	IPI	UniProtKB:O35627	Mouse	MGI:MGI:3762312|PMID:17904126
Molecular Function	GO:0005515	protein binding	Ect2	IPI	PR:P63001	Mouse	PMID:8464478
Molecular Function	GO:0042803	protein homodimerization activity	ECT2	IDA		Human	PMID:15545273
Molecular Function	GO:0031267	small GTPase binding	Ect2	IPI	PR:Q62159	Mouse	PMID:8464478
Cellular Component	GO:0005923	bicellular tight junction	ECT2	IDA		Human	PMID:15254234
Cellular Component	GO:0005911	cell-cell junction	ECT2	IDA		Human	PMID:15254234
Cellular Component	GO:0097149	centralspindlin complex	ECT2	IDA		Human	PMID:16236794
Cellular Component	GO:0032154	cleavage furrow	ECT2	IDA		Human	PMID:16103226
Cellular Component	GO:0032154	cleavage furrow	ECT2	IDA		Human	PMID:20047078
Cellular Component	GO:0005737	cytoplasm	ECT2	IDA		Human	PMID:16394104
Cellular Component	GO:0005737	cytoplasm	ECT2	IDA		Human	PMID:19617897
Cellular Component	GO:0005737	cytoplasm	ECT2	IDA		Human	PMID:20047078
Cellular Component	GO:0005737	cytoplasm	Ect2	IDA		Mouse	MGI:MGI:3762312|PMID:17904126
Cellular Component	GO:0005829	cytosol	ECT2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030496	midbody	ECT2	IDA		Human	PMID:15545273
Cellular Component	GO:0030496	midbody	ECT2	IDA		Human	PMID:16103226
Cellular Component	GO:0030496	midbody	ECT2	IDA		Human	PMID:16394104
Cellular Component	GO:0030496	midbody	ECT2	IDA		Human	PMID:19468300
Cellular Component	GO:0030496	midbody	ECT2	IDA		Human	PMID:20047078
Cellular Component	GO:0072686	mitotic spindle	ECT2	IDA		Human	PMID:15254234
Cellular Component	GO:0072686	mitotic spindle	ECT2	IDA		Human	PMID:16103226
Cellular Component	GO:0072686	mitotic spindle	ECT2	IDA		Human	PMID:16236794
Cellular Component	GO:0072686	mitotic spindle	ECT2	IDA		Human	PMID:20047078
Cellular Component	GO:0016604	nuclear body	ECT2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ECT2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ECT2	IDA		Human	PMID:15254234
Cellular Component	GO:0005634	nucleus	ECT2	IDA		Human	PMID:16103226
Cellular Component	GO:0005634	nucleus	ECT2	IDA		Human	PMID:19617897
Cellular Component	GO:0005634	nucleus	ECT2	IDA		Human	PMID:20047078
Cellular Component	GO:0005634	nucleus	Ect2	IDA		Mouse	MGI:MGI:3762312|PMID:17904126
Biological Process	GO:0090630	activation of GTPase activity	ECT2	IDA		Human	PMID:19617897
Biological Process	GO:0090630	activation of GTPase activity	ECT2	IMP		Human	PMID:19617897
Biological Process	GO:0032147	activation of protein kinase activity	ECT2	IDA		Human	PMID:15254234
Biological Process	GO:0070830	bicellular tight junction assembly	ECT2	IMP		Human	PMID:15254234
Biological Process	GO:0000902	cell morphogenesis	Ect2	IDA		Mouse	PMID:8464478
Biological Process	GO:0071277	cellular response to calcium ion	ECT2	IDA		Human	PMID:15254234
Biological Process	GO:0070301	cellular response to hydrogen peroxide	ECT2	IDA		Human	PMID:21373644
Biological Process	GO:0071479	cellular response to ionizing radiation	ECT2	IDA		Human	PMID:21373644
Biological Process	GO:0032506	cytokinetic process	ect2	IMP	ZFIN:ZDB-GENO-181227-12	Zfish	PMID:29486195
Biological Process	GO:0000281	mitotic cytokinesis	ECT2	IMP		Human	PMID:16236794
Biological Process	GO:0043065	positive regulation of apoptotic process	ECT2	IDA		Human	PMID:21373644
Biological Process	GO:0032467	positive regulation of cytokinesis	ECT2	IMP		Human	PMID:12761501
Biological Process	GO:0032467	positive regulation of cytokinesis	ECT2	IDA		Human	PMID:15545273
Biological Process	GO:0032467	positive regulation of cytokinesis	ECT2	IMP		Human	PMID:15642749
Biological Process	GO:0032467	positive regulation of cytokinesis	ECT2	IMP		Human	PMID:16103226
Biological Process	GO:0032467	positive regulation of cytokinesis	ECT2	IMP		Human	PMID:17115030
Biological Process	GO:0032467	positive regulation of cytokinesis	ECT2	IMP		Human	PMID:20047078
Biological Process	GO:0043547	positive regulation of GTPase activity	ECT2	IDA		Human	PMID:17115030
Biological Process	GO:0043547	positive regulation of GTPase activity	ECT2	IDA		Human	PMID:19617897
Biological Process	GO:0043547	positive regulation of GTPase activity	ECT2	IDA		Human	PMID:20047078
Biological Process	GO:0043547	positive regulation of GTPase activity	ECT2	IMP		Human	PMID:21373644
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	ECT2	HMP		Human	PMID:12761501
Biological Process	GO:0045666	positive regulation of neuron differentiation	Ect2	IMP		Mouse	MGI:MGI:5294522|PMID:21350944
Biological Process	GO:0042307	positive regulation of protein import into nucleus	Ect2	IDA		Mouse	MGI:MGI:3762312|PMID:17904126
Biological Process	GO:0051260	protein homooligomerization	ECT2	IDA		Human	PMID:15545273
Biological Process	GO:0051988	regulation of attachment of spindle microtubules to kinetochore	ECT2	IMP		Human	PMID:15642749
Biological Process	GO:0045859	regulation of protein kinase activity	ECT2	IDA		Human	PMID:15254234

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern