Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DYNC1LI2
  • Mouse genes Dync1li2
  • Rat genes Dync1li2
  • Zfish genes dync1li2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dync1li2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Dync1li2	IPI	RGD:621130	Rat	PMID:10893222|RGD:632618
Molecular Function	GO:0005515	protein binding	Dync1li2	IPI	PR:Q99NH2	Mouse	PMID:19540120
Cellular Component	GO:0005813	centrosome	DYNC1LI2	IDA		Human	PMID:21399614
Cellular Component	GO:0005813	centrosome	Dync1li2	IDA		Rat	PMID:21169557|RGD:13207422
Cellular Component	GO:0030286	dynein complex	DYNC1LI2	IPI		Human	PMID:24986880
Cellular Component	GO:0000776	kinetochore	Dync1li2	IDA		Rat	PMID:21169557|RGD:13207422
Cellular Component	GO:0005770	late endosome	Dync1li2	IDA		Rat	PMID:21169557|RGD:13207422
Cellular Component	GO:0005764	lysosome	Dync1li2	IDA		Rat	PMID:21169557|RGD:13207422
Cellular Component	GO:0016020	membrane	DYNC1LI2	HDA		Human	PMID:19946888
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	Dync1li2	IDA		Rat	PMID:11536324|RGD:13207410
Biological Process	GO:0051642	centrosome localization	Dync1li2	IMP		Mouse	PMID:19540120
Biological Process	GO:0000226	microtubule cytoskeleton organization	Dync1li2	IMP		Mouse	PMID:19540120
Biological Process	GO:0090235	regulation of metaphase plate congression	dync1li2	IMP	ZFIN:ZDB-MRPHLNO-170201-2	Zfish	PMID:28003657
Biological Process	GO:0009794	regulation of mitotic cell cycle, embryonic	dync1li2	IMP	ZFIN:ZDB-MRPHLNO-170201-1	Zfish	PMID:28003657
Biological Process	GO:0009794	regulation of mitotic cell cycle, embryonic	dync1li2	IMP	ZFIN:ZDB-MRPHLNO-170201-2	Zfish	PMID:28003657
Biological Process	GO:0060236	regulation of mitotic spindle organization	dync1li2	IMP	ZFIN:ZDB-MRPHLNO-170201-2	Zfish	PMID:28003657
Biological Process	GO:0060236	regulation of mitotic spindle organization	dync1li2	IMP	ZFIN:ZDB-MRPHLNO-170201-1	Zfish	PMID:28003657

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern