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Dync1li2 Gene Detail
Summary
  • Symbol
    Dync1li2
  • Name
    dynein, cytoplasmic 1 light intermediate chain 2
  • Synonyms
    Dncli2, Dnclic2, LIC2
  • Feature Type
    protein coding gene
  • IDs
    MGI:107738
    NCBI Gene: 234663
  • Gene Overview
    MyGene.info: DYNC1LI2
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:104417680-104443047 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 53.04 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    125 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107738
protein coding gene Chr8:104417674-104443051 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034010
protein coding gene Chr8:106555715-106581807 (-)
A/J MGP_AJ_G0033991
protein coding gene Chr8:102327226-102352716 (-)
AKR/J MGP_AKRJ_G0033917
protein coding gene Chr8:105300633-105327824 (-)
BALB/cJ MGP_BALBcJ_G0033984
protein coding gene Chr8:102550094-102576544 (-)
C3H/HeJ MGP_C3HHeJ_G0033696
protein coding gene Chr8:106004604-106032254 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034504
protein coding gene Chr8:110468719-110495438 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031447
protein coding gene Chr8:95613095-95638183 (-)
CAST/EiJ MGP_CASTEiJ_G0033023
protein coding gene Chr8:105554748-105580702 (-)
CBA/J MGP_CBAJ_G0033670
protein coding gene Chr8:114124504-114151929 (-)
DBA/2J MGP_DBA2J_G0033824
protein coding gene Chr8:101693782-101718868 (-)
FVB/NJ MGP_FVBNJ_G0033771
protein coding gene Chr8:100627351-100654120 (-)
LP/J MGP_LPJ_G0033915
protein coding gene Chr8:106750291-106779468 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033813
protein coding gene Chr8:117303987-117333075 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034522
protein coding gene Chr8:105243250-105270609 (-)
PWK/PhJ MGP_PWKPhJ_G0032725
protein coding gene Chr8:101103831-101128924 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032564
protein coding gene Chr8:104072828-104097857 (-)
WSB/EiJ MGP_WSBEiJ_G0033138
protein coding gene Chr8:105928441-105955427 (-)



Homology
more
  • Human Ortholog
    DYNC1LI2, dynein cytoplasmic 1 light intermediate chain 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DYNC1LI2, dynein cytoplasmic 1 light intermediate chain 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DNCLI2, LIC2
  • Links
    NCBI Gene ID: 1783
    neXtProt AC: NX_O43237
    UniProt: O43237

  • Chr Location
    16q22.1; chr16:66720893-66751828 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035770 Ensembl Gene Model | MGI Sequence Detail 25368 C57BL/6J ±  kb
transcript ENSMUST00000041769 Ensembl | MGI Sequence Detail 4627 Not Applicable  
polypeptide ENSMUSP00000045480 Ensembl | MGI Sequence Detail 492 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000006774 cytoplasmic dynein 1 light intermediate chain 2
  • InterPro Domains
    IPR008467 Dynein 1 light intermediate chain
    IPR022780 Dynein family light intermediate chain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-36314, MGI:2142418
References
more
  • Summaries
    All 31
    Gene Ontology 7
    Phenotypes 5
  • Earliest
    J:34934 Vaughan KT, et al., Multiple mouse chromosomal loci for dynein-based motility. Genomics. 1996 Aug 15;36(1):29-38
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory