Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DERL2
  • Mouse genes Derl2
  • Rat genes Derl2
  • Zfish genes derl2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Derl2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	DERL2	IPI	UniProtKB:P55072	Human	PMID:16449189
Molecular Function	GO:0005515	protein binding	DERL2	IPI	UniProtKB:Q92611	Human	PMID:16449189
Molecular Function	GO:0005515	protein binding	DERL2	IPI	UniProtKB:P60409	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DERL2	IPI	UniProtKB:P60410	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DERL2	IPI	UniProtKB:P43378	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL2	IPI	UniProtKB:Q00013	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL2	IPI	UniProtKB:Q8N0V3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL2	IPI	UniProtKB:Q8WV19	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL2	IPI	UniProtKB:Q9H0Q3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL2	IPI	UniProtKB:Q9NR28	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Derl2	IPI	UniProtKB:Q9D024	Mouse	MGI:MGI:5605216|PMID:25009997
Molecular Function	GO:0044877	protein-containing complex binding	DERL2	IPI	GO:0005785	Human	PMID:26565908
Molecular Function	GO:0005047	signal recognition particle binding	DERL2	IDA		Human	PMID:26565908
Cellular Component	GO:0005769	early endosome	Derl2	IDA		Mouse	PMID:19509052
Cellular Component	GO:0005783	endoplasmic reticulum	DERL2	IDA		Human	PMID:15215855
Cellular Component	GO:0005783	endoplasmic reticulum	Derl2	IDA		Mouse	PMID:19509052
Cellular Component	GO:0005789	endoplasmic reticulum membrane	DERL2	IDA		Human	PMID:16449189
Cellular Component	GO:0005770	late endosome	Derl2	IDA		Mouse	PMID:19509052
Cellular Component	GO:0016020	membrane	DERL2	HDA		Human	PMID:19946888
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	DERL2	IDA		Human	PMID:16449189
Biological Process	GO:1904153	negative regulation of retrograde protein transport, ER to cytosol	DERL2	IMP		Human	PMID:25660456
Biological Process	GO:0030307	positive regulation of cell growth	DERL2	IDA		Human	PMID:11500051
Biological Process	GO:0008284	positive regulation of cell population proliferation	DERL2	IDA		Human	PMID:11500051
Biological Process	GO:0030970	retrograde protein transport, ER to cytosol	DERL2	IMP		Human	PMID:16449189
Biological Process	GO:0030970	retrograde protein transport, ER to cytosol	Derl2	IMP	MGI:MGI:4947129	Mouse	PMID:21220515
Biological Process	GO:0001967	suckling behavior	Derl2	IMP	MGI:MGI:4947129	Mouse	PMID:21220515
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	DERL2	IMP		Human	PMID:16449189

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern