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Gene Ontology Browser
Term Detail
GO term:retrograde protein transport, ER to cytosol
Synonym: protein dislocation from ER
Synonym: protein retrotranslocation, ER to cytosol
Synonym: retrograde protein transport, endoplasmic reticulum to cytosol
GO id:GO:0030970
Definition:The directed movement of unfolded or misfolded proteins from the endoplasmic reticulum to the cytosol through the translocon.
Number of paths to term: 34

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-acellular response to stress
                                        is-aresponse to endoplasmic reticulum stress
                                                is-aERAD pathway
                                                        part-ofER-associated ubiquitin-dependent protein catabolic process +
                                                        is-aglycoprotein ERAD pathway +
                                                        part-ofmaintenance of unfolded protein involved in ERAD pathway
                                                        negatively-regulatesnegative regulation of ERAD pathway +
                                                        positively-regulatespositive regulation of ERAD pathway +
                                                        part-ofprotein localization to cytosolic proteasome complex involved in ERAD pathway
                                                        regulatesregulation of ERAD pathway +
                                                        part-ofretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-aERAD pathway
                                        part-ofER-associated ubiquitin-dependent protein catabolic process +
                                        is-aglycoprotein ERAD pathway +
                                        part-ofmaintenance of unfolded protein involved in ERAD pathway
                                        negatively-regulatesnegative regulation of ERAD pathway +
                                        positively-regulatespositive regulation of ERAD pathway +
                                        part-ofprotein localization to cytosolic proteasome complex involved in ERAD pathway
                                        regulatesregulation of ERAD pathway +
                                        part-ofretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-acellular localization
                                is-acellular macromolecule localization
                                        is-acellular protein localization
                                                part-ofintracellular protein transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-acellular localization
                                part-ofestablishment of localization in cell
                                        is-aintracellular transport
                                                is-acytoplasmic transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-acellular localization
                                part-ofestablishment of localization in cell
                                        is-aintracellular transport
                                                is-aintracellular protein transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-acellular localization
                                part-ofestablishment of localization in cell
                                        is-aintracellular transport
                                                is-asingle-organism intracellular transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-aestablishment of localization in cell
                                        is-aintracellular transport
                                                is-acytoplasmic transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-aestablishment of localization in cell
                                        is-aintracellular transport
                                                is-aintracellular protein transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-aestablishment of localization in cell
                                        is-aintracellular transport
                                                is-asingle-organism intracellular transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-aestablishment of protein localization
                                        is-aprotein transport
                                                is-aintracellular protein transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-aendoplasmic reticulum to cytosol transport
                                                is-acalcium ion transport from endoplasmic reticulum to cytosol +
                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-aintracellular transport
                                                is-acytoplasmic transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-aintracellular transport
                                                is-aintracellular protein transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-aintracellular transport
                                                is-asingle-organism intracellular transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-aorganic substance transport
                                                is-aprotein transport
                                                        is-aintracellular protein transport
                                                                is-aprotein exit from endoplasmic reticulum
                                                                        negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                        positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                        regulatesregulation of protein exit from endoplasmic reticulum +
                                                                        is-aretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                                part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                                negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                                positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                                regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-asingle-organism transport
                                                is-asingle-organism intracellular transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-amacromolecule localization
                                is-acellular macromolecule localization
                                        is-acellular protein localization
                                                part-ofintracellular protein transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-amacromolecule localization
                                is-aprotein localization
                                        is-acellular protein localization
                                                part-ofintracellular protein transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-amacromolecule localization
                                is-aprotein localization
                                        part-ofestablishment of protein localization
                                                is-aprotein transport
                                                        is-aintracellular protein transport
                                                                is-aprotein exit from endoplasmic reticulum
                                                                        negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                        positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                        regulatesregulation of protein exit from endoplasmic reticulum +
                                                                        is-aretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                                part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                                negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                                positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                                regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-amacromolecule localization
                                is-aprotein localization
                                        is-aprotein transport
                                                is-aintracellular protein transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-asingle-organism localization
                                is-asingle-organism transport
                                        is-asingle-organism intracellular transport
                                                is-aprotein exit from endoplasmic reticulum
                                                        negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                        positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                        regulatesregulation of protein exit from endoplasmic reticulum +
                                                        is-aretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acatabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-aprotein catabolic process
                                                        is-aERAD pathway
                                                                part-ofER-associated ubiquitin-dependent protein catabolic process +
                                                                is-aglycoprotein ERAD pathway +
                                                                part-ofmaintenance of unfolded protein involved in ERAD pathway
                                                                negatively-regulatesnegative regulation of ERAD pathway +
                                                                positively-regulatespositive regulation of ERAD pathway +
                                                                part-ofprotein localization to cytosolic proteasome complex involved in ERAD pathway
                                                                regulatesregulation of ERAD pathway +
                                                                part-ofretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acatabolic process
                                is-asingle-organism catabolic process
                                        is-aERAD pathway
                                                part-ofER-associated ubiquitin-dependent protein catabolic process +
                                                is-aglycoprotein ERAD pathway +
                                                part-ofmaintenance of unfolded protein involved in ERAD pathway
                                                negatively-regulatesnegative regulation of ERAD pathway +
                                                positively-regulatespositive regulation of ERAD pathway +
                                                part-ofprotein localization to cytosolic proteasome complex involved in ERAD pathway
                                                regulatesregulation of ERAD pathway +
                                                part-ofretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-amacromolecule catabolic process
                                                is-aprotein catabolic process
                                                        is-aERAD pathway
                                                                part-ofER-associated ubiquitin-dependent protein catabolic process +
                                                                is-aglycoprotein ERAD pathway +
                                                                part-ofmaintenance of unfolded protein involved in ERAD pathway
                                                                negatively-regulatesnegative regulation of ERAD pathway +
                                                                positively-regulatespositive regulation of ERAD pathway +
                                                                part-ofprotein localization to cytosolic proteasome complex involved in ERAD pathway
                                                                regulatesregulation of ERAD pathway +
                                                                part-ofretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                is-aprotein catabolic process
                                                        is-aERAD pathway
                                                                part-ofER-associated ubiquitin-dependent protein catabolic process +
                                                                is-aglycoprotein ERAD pathway +
                                                                part-ofmaintenance of unfolded protein involved in ERAD pathway
                                                                negatively-regulatesnegative regulation of ERAD pathway +
                                                                positively-regulatespositive regulation of ERAD pathway +
                                                                part-ofprotein localization to cytosolic proteasome complex involved in ERAD pathway
                                                                regulatesregulation of ERAD pathway +
                                                                part-ofretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-aprotein catabolic process
                                                        is-aERAD pathway
                                                                part-ofER-associated ubiquitin-dependent protein catabolic process +
                                                                is-aglycoprotein ERAD pathway +
                                                                part-ofmaintenance of unfolded protein involved in ERAD pathway
                                                                negatively-regulatesnegative regulation of ERAD pathway +
                                                                positively-regulatespositive regulation of ERAD pathway +
                                                                part-ofprotein localization to cytosolic proteasome complex involved in ERAD pathway
                                                                regulatesregulation of ERAD pathway +
                                                                part-ofretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-aprotein metabolic process
                                        is-aprotein catabolic process
                                                is-aERAD pathway
                                                        part-ofER-associated ubiquitin-dependent protein catabolic process +
                                                        is-aglycoprotein ERAD pathway +
                                                        part-ofmaintenance of unfolded protein involved in ERAD pathway
                                                        negatively-regulatesnegative regulation of ERAD pathway +
                                                        positively-regulatespositive regulation of ERAD pathway +
                                                        part-ofprotein localization to cytosolic proteasome complex involved in ERAD pathway
                                                        regulatesregulation of ERAD pathway +
                                                        part-ofretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-asingle-organism metabolic process
                                is-asingle-organism catabolic process
                                        is-aERAD pathway
                                                part-ofER-associated ubiquitin-dependent protein catabolic process +
                                                is-aglycoprotein ERAD pathway +
                                                part-ofmaintenance of unfolded protein involved in ERAD pathway
                                                negatively-regulatesnegative regulation of ERAD pathway +
                                                positively-regulatespositive regulation of ERAD pathway +
                                                part-ofprotein localization to cytosolic proteasome complex involved in ERAD pathway
                                                regulatesregulation of ERAD pathway +
                                                part-ofretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-acellular response to stress
                                        is-aresponse to endoplasmic reticulum stress
                                                is-aERAD pathway
                                                        part-ofER-associated ubiquitin-dependent protein catabolic process +
                                                        is-aglycoprotein ERAD pathway +
                                                        part-ofmaintenance of unfolded protein involved in ERAD pathway
                                                        negatively-regulatesnegative regulation of ERAD pathway +
                                                        positively-regulatespositive regulation of ERAD pathway +
                                                        part-ofprotein localization to cytosolic proteasome complex involved in ERAD pathway
                                                        regulatesregulation of ERAD pathway +
                                                        part-ofretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to organic substance
                                        is-aERAD pathway
                                                part-ofER-associated ubiquitin-dependent protein catabolic process +
                                                is-aglycoprotein ERAD pathway +
                                                part-ofmaintenance of unfolded protein involved in ERAD pathway
                                                negatively-regulatesnegative regulation of ERAD pathway +
                                                positively-regulatespositive regulation of ERAD pathway +
                                                part-ofprotein localization to cytosolic proteasome complex involved in ERAD pathway
                                                regulatesregulation of ERAD pathway +
                                                part-ofretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to stress
                                is-acellular response to stress
                                        is-aresponse to endoplasmic reticulum stress
                                                is-aERAD pathway
                                                        part-ofER-associated ubiquitin-dependent protein catabolic process +
                                                        is-aglycoprotein ERAD pathway +
                                                        part-ofmaintenance of unfolded protein involved in ERAD pathway
                                                        negatively-regulatesnegative regulation of ERAD pathway +
                                                        positively-regulatespositive regulation of ERAD pathway +
                                                        part-ofprotein localization to cytosolic proteasome complex involved in ERAD pathway
                                                        regulatesregulation of ERAD pathway +
                                                        part-ofretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-aERAD pathway
                                        part-ofER-associated ubiquitin-dependent protein catabolic process +
                                        is-aglycoprotein ERAD pathway +
                                        part-ofmaintenance of unfolded protein involved in ERAD pathway
                                        negatively-regulatesnegative regulation of ERAD pathway +
                                        positively-regulatespositive regulation of ERAD pathway +
                                        part-ofprotein localization to cytosolic proteasome complex involved in ERAD pathway
                                        regulatesregulation of ERAD pathway +
                                        part-ofretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism localization
                                is-asingle-organism transport
                                        is-asingle-organism intracellular transport
                                                is-aprotein exit from endoplasmic reticulum
                                                        negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                        positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                        regulatesregulation of protein exit from endoplasmic reticulum +
                                                        is-aretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                                part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                                negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                regulatesregulation of retrograde protein transport, ER to cytosol +


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism metabolic process
                                is-asingle-organism catabolic process
                                        is-aERAD pathway
                                                part-ofER-associated ubiquitin-dependent protein catabolic process +
                                                is-aglycoprotein ERAD pathway +
                                                part-ofmaintenance of unfolded protein involved in ERAD pathway
                                                negatively-regulatesnegative regulation of ERAD pathway +
                                                positively-regulatespositive regulation of ERAD pathway +
                                                part-ofprotein localization to cytosolic proteasome complex involved in ERAD pathway
                                                regulatesregulation of ERAD pathway +
                                                part-ofretrograde protein transport, ER to cytosol [GO:0030970] (27 genes, 32 annotations)
                                                        part-ofmembrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory