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Gene Ontology Browser
Term Detail
GO term:retrograde protein transport, ER to cytosol
Synonym: protein dislocation from ER
Synonym: retrograde protein transport, endoplasmic reticulum to cytosol
GO id:GO:0030970
Definition:The directed movement of unfolded or misfolded proteins from the endoplasmic reticulum to the cytosol through the translocon.
Number of paths to term: 21

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-acellular localization
                                is-acellular macromolecule localization
                                        is-acellular protein localization
                                                part-ofintracellular protein transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (22 genes, 25 annotations)
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-acellular localization
                                part-ofestablishment of localization in cell
                                        is-aintracellular transport
                                                is-acytoplasmic transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (22 genes, 25 annotations)
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-acellular localization
                                part-ofestablishment of localization in cell
                                        is-aintracellular transport
                                                is-aintracellular protein transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (22 genes, 25 annotations)
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-acellular localization
                                part-ofestablishment of localization in cell
                                        is-aintracellular transport
                                                is-asingle-organism intracellular transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (22 genes, 25 annotations)
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-aestablishment of localization in cell
                                        is-aintracellular transport
                                                is-acytoplasmic transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (22 genes, 25 annotations)
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-aestablishment of localization in cell
                                        is-aintracellular transport
                                                is-aintracellular protein transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (22 genes, 25 annotations)
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-aestablishment of localization in cell
                                        is-aintracellular transport
                                                is-asingle-organism intracellular transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (22 genes, 25 annotations)
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-aestablishment of protein localization
                                        is-aprotein transport
                                                is-aintracellular protein transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (22 genes, 25 annotations)
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-aendoplasmic reticulum to cytosol transport
                                                is-acalcium ion transport from endoplasmic reticulum to cytosol +
                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (22 genes, 25 annotations)
                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-aintracellular transport
                                                is-acytoplasmic transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (22 genes, 25 annotations)
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-aintracellular transport
                                                is-aintracellular protein transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (22 genes, 25 annotations)
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-aintracellular transport
                                                is-asingle-organism intracellular transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (22 genes, 25 annotations)
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-aorganic substance transport
                                                is-aprotein transport
                                                        is-aintracellular protein transport
                                                                is-aprotein exit from endoplasmic reticulum
                                                                        negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                        positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                        regulatesregulation of protein exit from endoplasmic reticulum +
                                                                        is-aretrograde protein transport, ER to cytosol [GO:0030970] (22 genes, 25 annotations)
                                                                                negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                                positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                                regulatesregulation of retrograde protein transport, ER to cytosol +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-asingle-organism transport
                                                is-asingle-organism intracellular transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (22 genes, 25 annotations)
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-amacromolecule localization
                                is-acellular macromolecule localization
                                        is-acellular protein localization
                                                part-ofintracellular protein transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (22 genes, 25 annotations)
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-amacromolecule localization
                                is-aprotein localization
                                        is-acellular protein localization
                                                part-ofintracellular protein transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (22 genes, 25 annotations)
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-amacromolecule localization
                                is-aprotein localization
                                        part-ofestablishment of protein localization
                                                is-aprotein transport
                                                        is-aintracellular protein transport
                                                                is-aprotein exit from endoplasmic reticulum
                                                                        negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                        positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                        regulatesregulation of protein exit from endoplasmic reticulum +
                                                                        is-aretrograde protein transport, ER to cytosol [GO:0030970] (22 genes, 25 annotations)
                                                                                negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                                positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                                regulatesregulation of retrograde protein transport, ER to cytosol +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-amacromolecule localization
                                is-aprotein localization
                                        is-aprotein transport
                                                is-aintracellular protein transport
                                                        is-aprotein exit from endoplasmic reticulum
                                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (22 genes, 25 annotations)
                                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-asingle-organism localization
                                is-asingle-organism transport
                                        is-asingle-organism intracellular transport
                                                is-aprotein exit from endoplasmic reticulum
                                                        negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                        positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                        regulatesregulation of protein exit from endoplasmic reticulum +
                                                        is-aretrograde protein transport, ER to cytosol [GO:0030970] (22 genes, 25 annotations)
                                                                negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                regulatesregulation of retrograde protein transport, ER to cytosol +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism localization
                                is-asingle-organism transport
                                        is-asingle-organism intracellular transport
                                                is-aprotein exit from endoplasmic reticulum
                                                        negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                        positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                        regulatesregulation of protein exit from endoplasmic reticulum +
                                                        is-aretrograde protein transport, ER to cytosol [GO:0030970] (22 genes, 25 annotations)
                                                                negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                                positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                                regulatesregulation of retrograde protein transport, ER to cytosol +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism transport
                                is-asingle-organism intracellular transport
                                        is-aprotein exit from endoplasmic reticulum
                                                negatively-regulatesnegative regulation of protein exit from endoplasmic reticulum +
                                                positively-regulatespositive regulation of protein exit from endoplasmic reticulum +
                                                regulatesregulation of protein exit from endoplasmic reticulum +
                                                is-aretrograde protein transport, ER to cytosol [GO:0030970] (22 genes, 25 annotations)
                                                        negatively-regulatesnegative regulation of retrograde protein transport, ER to cytosol
                                                        positively-regulatespositive regulation of retrograde protein transport, ER to cytosol
                                                        regulatesregulation of retrograde protein transport, ER to cytosol +


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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory