Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CGA
  • Mouse genes Cga
  • Rat genes Cga
  • Zfish genes cga
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cga

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016913	follicle-stimulating hormone activity	CGA	IDA		Human	PMID:24692546
Molecular Function	GO:0016913	follicle-stimulating hormone activity	CGA	IDA		Human	PMID:2494176
Molecular Function	GO:0005179	hormone activity	CGA	IMP		Human	PMID:11207219
Molecular Function	GO:0005515	protein binding	CGA	IPI	UniProtKB:P01225	Human	PMID:11222739
Molecular Function	GO:0005515	protein binding	CGA	IPI	UniProtKB:P01225	Human	PMID:15662415
Molecular Function	GO:0005515	protein binding	CGA	IPI	UniProtKB:P01225	Human	PMID:22802634
Molecular Function	GO:0005515	protein binding	CGA	IPI	UniProtKB:P0DN86	Human	PMID:31467278
Molecular Function	GO:0005515	protein binding	CGA	IPI	UniProtKB:P0DN86	Human	PMID:7922031
Cellular Component	GO:0005615	extracellular space	CGA	IDA		Human	PMID:24692546
Cellular Component	GO:0005615	extracellular space	CGA	IDA		Human	PMID:2494176
Cellular Component	GO:0016914	follicle-stimulating hormone complex	CGA	IPI		Human	PMID:11222739
Cellular Component	GO:0016914	follicle-stimulating hormone complex	CGA	IDA		Human	PMID:24692546
Cellular Component	GO:0016914	follicle-stimulating hormone complex	CGA	IDA		Human	PMID:2494176
Cellular Component	GO:0061696	pituitary gonadotropin complex	CGA	IPI		Human	PMID:7922031
Biological Process	GO:0032870	cellular response to hormone stimulus	Cga	IMP	MGI:MGI:1857152	Mouse	PMID:12114718
Biological Process	GO:0048589	developmental growth	Cga	IMP	MGI:MGI:1857152	Mouse	PMID:12114718
Biological Process	GO:0046884	follicle-stimulating hormone secretion	Cga	IMP	MGI:MGI:1857152	Mouse	PMID:12114718
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	CGA	IDA		Human	PMID:24692546
Biological Process	GO:0008406	gonad development	Cga	IMP	MGI:MGI:1857152	Mouse	PMID:12114718
Biological Process	GO:0032275	luteinizing hormone secretion	Cga	IMP	MGI:MGI:1857152	Mouse	PMID:12114718
Biological Process	GO:0046621	negative regulation of organ growth	Cga	IMP	MGI:MGI:1857152	Mouse	PMID:12114718
Biological Process	GO:0035265	organ growth	Cga	IMP	MGI:MGI:1857152	Mouse	PMID:12114718
Biological Process	GO:0010893	positive regulation of steroid biosynthetic process	CGA	IDA		Human	PMID:2494176
Biological Process	GO:0010469	regulation of signaling receptor activity	CGA	IDA		Human	PMID:24692546
Biological Process	GO:0030878	thyroid gland development	Cga	IMP	MGI:MGI:1857152	Mouse	PMID:12114718
Biological Process	GO:0006590	thyroid hormone generation	Cga	IMP	MGI:MGI:1857152	Mouse	PMID:12114718

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern