Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDX1
  • Mouse genes Cdx1
  • Rat genes Cdx1
  • Zfish genes cdx1a,cdx1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdx1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	CDX1	IDA		Human	PMID:15774940
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Cdx1	IDA		Mouse	MGI:MGI:5301472|PMID:22015720
Molecular Function	GO:0003700	DNA-binding transcription factor activity	cdx1b	IPI	ZFIN:ZDB-GENE-980526-404	Zfish	PMID:18234726
Molecular Function	GO:0008327	methyl-CpG binding	CDX1	IDA		Human	PMID:28473536
Molecular Function	GO:1990841	promoter-specific chromatin binding	cdx1b	IDA		Zfish	PMID:33197427
Molecular Function	GO:0005515	protein binding	CDX1	IPI	UniProtKB:P49715	Human	PMID:19059241
Molecular Function	GO:0005515	protein binding	Cdx1	IPI	UniProtKB:P20226	Mouse	MGI:MGI:6294231|PMID:17158164
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	CDX1	IDA		Human	PMID:15774940
Molecular Function	GO:0043565	sequence-specific DNA binding	cdx1b	IPI	ZFIN:ZDB-GENE-980526-404	Zfish	PMID:18234726
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	CDX1	IDA		Human	PMID:28473536
Molecular Function	GO:0000976	transcription cis-regulatory region binding	CDX1	IDA		Human	PMID:24623306
Biological Process	GO:0009948	anterior/posterior axis specification	cdx1a	IGI	ZFIN:ZDB-GENE-000823-1,ZFIN:ZDB-GENO-980202-1126,ZFIN:ZDB-MRPHLNO-060602-1	Zfish	PMID:16457800
Biological Process	GO:0009948	anterior/posterior axis specification	cdx1a	IGI	ZFIN:ZDB-GENE-000329-2,ZFIN:ZDB-GENO-980202-1126,ZFIN:ZDB-MRPHLNO-060602-1	Zfish	PMID:16457800
Biological Process	GO:0009952	anterior/posterior pattern specification	Cdx1	IMP	MGI:MGI:2154514	Mouse	PMID:11784046
Biological Process	GO:0009952	anterior/posterior pattern specification	Cdx1	IGI	MGI:MGI:97858	Mouse	PMID:11784046
Biological Process	GO:0009952	anterior/posterior pattern specification	Cdx1	IMP	MGI:MGI:2154514	Mouse	PMID:7585967
Biological Process	GO:0009952	anterior/posterior pattern specification	cdx1a	IGI	ZFIN:ZDB-GENO-080715-2,ZFIN:ZDB-MRPHLNO-050509-3	Zfish	PMID:18234725
Biological Process	GO:0009952	anterior/posterior pattern specification	cdx1a	IGI	ZFIN:ZDB-GENO-080215-1,ZFIN:ZDB-MRPHLNO-060602-1	Zfish	PMID:17953490
Biological Process	GO:0060349	bone morphogenesis	Cdx1	IGI	MGI:MGI:97858	Mouse	PMID:11784046
Biological Process	GO:0060349	bone morphogenesis	Cdx1	IMP	MGI:MGI:2154514	Mouse	PMID:11784046
Biological Process	GO:0035462	determination of left/right asymmetry in diencephalon	cdx1b	IMP	ZFIN:ZDB-GENO-220527-3	Zfish	PMID:33197427
Biological Process	GO:0048565	digestive tract development	cdx1b	IMP	ZFIN:ZDB-MRPHLNO-080707-1	Zfish	PMID:19253392
Biological Process	GO:0048546	digestive tract morphogenesis	cdx1b	IMP	ZFIN:ZDB-MRPHLNO-090217-1	Zfish	PMID:18804112
Biological Process	GO:0048546	digestive tract morphogenesis	cdx1b	IMP	ZFIN:ZDB-MRPHLNO-090217-2	Zfish	PMID:18804112
Biological Process	GO:0048546	digestive tract morphogenesis	cdx1b	IMP	ZFIN:ZDB-MRPHLNO-080707-1	Zfish	PMID:18234726
Biological Process	GO:0001706	endoderm formation	cdx1b	IMP	ZFIN:ZDB-MRPHLNO-080707-1	Zfish	PMID:18234726
Biological Process	GO:0030855	epithelial cell differentiation	cdx1b	IMP	ZFIN:ZDB-MRPHLNO-090217-1	Zfish	PMID:18804112
Biological Process	GO:0050673	epithelial cell proliferation	cdx1b	IMP	ZFIN:ZDB-MRPHLNO-090217-1	Zfish	PMID:18804112
Biological Process	GO:0030097	hemopoiesis	cdx1a	IGI	ZFIN:ZDB-GENO-980202-1126,ZFIN:ZDB-MRPHLNO-060602-1	Zfish	PMID:16457800
Biological Process	GO:0021906	hindbrain-spinal cord boundary formation	cdx1a	IMP	ZFIN:ZDB-MRPHLNO-050509-3	Zfish	PMID:17507415
Biological Process	GO:0060575	intestinal epithelial cell differentiation	cdx1b	IMP	ZFIN:ZDB-MRPHLNO-080707-1	Zfish	PMID:19253392
Biological Process	GO:0001889	liver development	cdx1b	IMP	ZFIN:ZDB-MRPHLNO-080707-1	Zfish	PMID:18234726
Biological Process	GO:0031016	pancreas development	cdx1a	IGI	ZFIN:ZDB-GENO-080715-2,ZFIN:ZDB-MRPHLNO-050509-3	Zfish	PMID:18234725
Biological Process	GO:0031016	pancreas development	cdx1b	IMP	ZFIN:ZDB-MRPHLNO-080707-1	Zfish	PMID:18234726
Biological Process	GO:0007389	pattern specification process	Cdx1	IMP	MGI:MGI:2154514	Mouse	PMID:11959827
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	cdx1b	IGI	ZFIN:ZDB-GENE-980526-404	Zfish	PMID:18234726
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CDX1	IDA		Human	PMID:15774940
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CDX1	IMP		Human	PMID:24623306
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Cdx1	IDA		Mouse	PMID:7585967
Biological Process	GO:0048793	pronephros development	cdx1a	IGI	ZFIN:ZDB-GENO-080215-1,ZFIN:ZDB-MRPHLNO-060602-1	Zfish	PMID:17953490
Biological Process	GO:0014807	regulation of somitogenesis	Cdx1	IMP		Mouse	MGI:MGI:5301472|PMID:22015720
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	cdx1a	IGI	ZFIN:ZDB-GENO-080215-1,ZFIN:ZDB-MRPHLNO-060602-1	Zfish	PMID:17953490
Biological Process	GO:0021903	rostrocaudal neural tube patterning	cdx1a	IGI	ZFIN:ZDB-MRPHLNO-050509-3,ZFIN:ZDB-MRPHLNO-050509-7	Zfish	PMID:17079270
Biological Process	GO:0001756	somitogenesis	cdx1a	IGI	ZFIN:ZDB-MRPHLNO-050509-7	Zfish	PMID:15708563

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern