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Cdx1
Gene Detail
 Symbol
Name
ID
Cdx1
caudal type homeobox 1
MGI:88360
Synonyms Cdx, Cdx-1
Feature Type protein coding gene
Genetic Map
Chromosome 18
34.41 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr18:61018862-61036199 bp, - strand
From VEGA annotation of GRCm38

  17338 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1366  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Cdx1

Human
homologs
Human Homolog CDX1, caudal type homeobox 1
NCBI Gene ID 1044
neXtProt AC  NX_P47902
Human Chr (Location)  5q32; chr5:150166781-150184558 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(1) Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene results in abnormalities of the basiocciptal bone, vertebrae, and ribs.
 
Interactions
Cdx1 interacts with 122 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process anterior/posterior pattern specification, bone morphogenesis, ...
Component nucleus
Function DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (47 records)
Data Summary: Results (242)    Tissues (145)    Images (62)
Theiler Stages: 2, 3, 4, 5, 6, 9, 10, 11, 12, 13, 14, 15, 16, 17, 19, 20, 21, 22, 23, 24, 25, 26, 28
Assay TypeResults
Immunohistochemistry 52
RNA in situ 93
Northern blot 22
Western blot 4
RT-PCR 66
RNase protection 5
cDNA source data(39)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(55) Genomic(5) cDNA(39) Primer pair(7) Other(4)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000037224 (Evidence)
Ensembl Gene ModelENSMUSG00000024619 (Evidence)
Entrez Gene12590 (Evidence)
UniGene144448
DFCITC1584508
DoTSDT.531035
NIA Mouse Gene IndexU038465
Consensus CDS ProjectCCDS29279.1
International Mouse Knockout Project StatusCdx1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037224 VEGA Gene Model | MGI Sequence Detail 17338 C57BL/6J ±  kb
transcript OTTMUST00000095993 VEGA | MGI Sequence Detail 1750 Not Applicable 
polypeptide OTTMUSP00000053587 VEGA | MGI Sequence Detail 268 Not Applicable 

For the selected sequences
All sequences(16) RefSeq(2) UniProt(1)
Polymorphisms RFLP(3) : SNPs within 2kb(135 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006820 Caudal-like activation domain
InterPro IPR000047 Helix-turn-helix motif
InterPro IPR017970 Homeobox, conserved site
InterPro IPR001356 Homeodomain
InterPro IPR009057 Homeodomain-like
InterPro IPR020479 Homeodomain, metazoa
Protein Ontology PR:000005295 homeobox protein CDX-1
References (Earliest) J:9557 Duprey P, et al., A mouse gene homologous to the Drosophila gene caudal is expressed in epithelial cells from the embryonic intestine. Genes Dev. 1988 Dec;2(12A):1647-54
(Latest) J:194978 Reichmann J, et al., The genome-defence gene Tex19.1 suppresses LINE-1 retrotransposons in the placenta and prevents intra-uterine growth retardation in mice. Hum Mol Genet. 2013 May 1;22(9):1791-806
All references(100)
Other
accession IDs
MGD-MRK-1888, MGD-MRK-1889, MGD-MRK-1893

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory