Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes C1QC
  • Mouse genes C1qc
  • Rat genes C1qc
  • Zfish genes c1qc
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set C1qc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	C1QC	IPI	UniProtKB:Q07021:PRO_0000018590	Human	PMID:28018340
Molecular Function	GO:0005515	protein binding	C1QC	IPI	UniProtKB:Q76KX8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	C1QC	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Cellular Component	GO:0072562	blood microparticle	C1QC	HDA		Human	PMID:22516433
Cellular Component	GO:0062023	collagen-containing extracellular matrix	C1QC	HDA		Human	PMID:28344315
Cellular Component	GO:0062023	collagen-containing extracellular matrix	C1QC	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	C1QC	HDA		Human	PMID:28675934
Cellular Component	GO:0062167	complement component C1q complex	C1QC	IPI		Human	PMID:29449492
Cellular Component	GO:0005576	extracellular region	C1QC	IDA		Human	PMID:18250442
Cellular Component	GO:0005615	extracellular space	C1QC	HDA		Human	PMID:22664934
Cellular Component	GO:0005615	extracellular space	C1qc	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0098794	postsynapse	C1qc	IGI	ComplexPortal:CPX-1180,UniProtKB:P14106,UniProtKB:P98086	Mouse	MGI:MGI:6275119|PMID:27033548
Cellular Component	GO:0045202	synapse	C1qc	IDA		Mouse	MGI:MGI:3801262|PMID:18083105
Cellular Component	GO:0045202	synapse	C1qc	IGI	UniProtKB:P14106,UniProtKB:P98086	Mouse	MGI:MGI:3801262|PMID:18083105
Cellular Component	GO:0045202	synapse	C1qc	IDA		Rat	PMID:18083105|RGD:13838802
Biological Process	GO:0006958	complement activation, classical pathway	C1QC	IDA		Human	PMID:29449492
Biological Process	GO:0006958	complement activation, classical pathway	c1qc	IDA		Zfish	PMID:20615881
Biological Process	GO:0030853	negative regulation of granulocyte differentiation	C1QC	IDA		Human	PMID:10961870
Biological Process	GO:0045650	negative regulation of macrophage differentiation	C1QC	IDA		Human	PMID:10961870
Biological Process	GO:0098883	synapse pruning	C1qc	IGI	UniProtKB:P14106,UniProtKB:P98086	Mouse	MGI:MGI:6275119|PMID:27033548

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern