About   Help   FAQ
C1qc
Gene Detail
Symbol

Name
ID
C1qc
complement component 1, q subcomponent, C chain
MGI:88225
Synonyms
C1qg
Feature Type
protein coding gene
Genetic Map
Chromosome 4
69.05 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr4:136889804-136893065 bp, - strand
From VEGA annotation of GRCm38

  3262 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32020  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: C1QC
Protein SuperFamily: complement subcomponent C1q chain A
Gene Tree: C1qc

Human
homologs
C1QC, complement component 1, q subcomponent, C chain
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 714
neXtProt AC: NX_P02747

Human Synonyms: C1Q-C, C1QG

Human Chr (Location): 1p36.11; chr1:22643625-22648110 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human C1QC

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Genomic Mutations involving C1qc (1)
Incidental mutations (data from APF , CvDC )
Interactions
C1qc interacts with 38 markers (Mir203, Mir221, Mir298, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process complement activation, classical pathway, immune response, ...
Component blood microparticle, collagen trimer, ...
Function tumor necrosis factor receptor binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(41)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: ZFIN c1qc    NEW 
Molecular
reagents
All nucleic(45) Genomic(3) cDNA(42)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000009764 (Evidence)
Ensembl Gene Model ENSMUSG00000036896 (Evidence)
Entrez Gene 12262 (Evidence)
UniGene 439732
DFCI TC1581813, TC1605972
DoTS DT.101255106, DT.526099, DT.94187664, DT.94359585
NIA Mouse Gene Index U025673
Consensus CDS Project CCDS18811.1
International Mouse Phenotyping Consortium Status C1qc
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009764 VEGA Gene Model | MGI Sequence Detail 3262 C57BL/6J ±  kb
transcript OTTMUST00000022607 VEGA | MGI Sequence Detail 1203 Not Applicable 
polypeptide OTTMUSP00000010320 VEGA | MGI Sequence Detail 246 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(2) UniProt(1)
Polymorphisms
RFLP(1) : SNPs within 2kb(86 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008160 Collagen triple helix repeat
InterPro IPR001073 Complement C1q protein
InterPro IPR006052 Tumour necrosis factor
InterPro IPR008983 Tumour necrosis factor-like domain
Protein Ontology PR:000004878 complement C1q subcomponent subunit C
References
(Earliest) J:3065 Petry F, et al., Isolation, sequence analysis and characterization of cDNA clones coding for the C chain of mouse C1q. Sequence similarity of complement subcomponent C1q, collagen type VIII and type X and precerebellin. Eur J Biochem. 1992 Oct 1;209(1):129-34
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(31)
Other
accession IDs
MGD-MRK-1698, MGI:2140252

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/20/2015
MGI 5.22
The Jackson Laboratory