C1qc
Gene Detail

Symbol Name ID

C1qc complement component 1, q subcomponent, C chain MGI:88225

Synonyms

C1qg

Feature Type

protein coding gene

Genetic Map

Chromosome 4

69.05 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)

Sequence Map

Chr4:136889804-136893065 bp, - strand From VEGA annotation of GRCm38   3262 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:32020  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: complement subcomponent C1q chain A
Gene Tree: C1qc

Human homologs

Human Homolog		C1QC, complement component 1, q subcomponent, C chain
NCBI Gene ID		714
neXtProt AC		NX_P02747
Human Synonyms		C1Q-C, C1QG
Human Chr (Location)		1p36.11; chr1:22970118-22974603 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human C1QC

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	complement activation, classical pathway, immune response, ...
Component	collagen, extracellular region, ...
Function	tumor necrosis factor receptor binding

External Resources: FuncBase

Expression

Literature Summary: (1 records)
cDNA source data(41)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(45) Genomic(3) cDNA(42)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000009764 (Evidence)
Ensembl Gene Model	ENSMUSG00000036896 (Evidence)
Entrez Gene	12262 (Evidence)
UniGene	439732
DFCI	TC1581813, TC1605972
DoTS	DT.101255106, DT.526099, DT.94187664, DT.94359585
NIA Mouse Gene Index	U025673
Consensus CDS Project	CCDS18811.1
International Mouse Knockout Project Status	C1qc

Sequences

Length	Strain/Species
genomic	OTTMUSG00000009764	VEGA Gene Model | MGI Sequence Detail	3262	C57BL/6J
transcript	OTTMUST00000022607	VEGA | MGI Sequence Detail	1203	Not Applicable
polypeptide	OTTMUSP00000010320	VEGA | MGI Sequence Detail	246	Not Applicable

All sequences(29) RefSeq(2) UniProt(1)

Polymorphisms

RFLP(1) : SNPs(44 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR008160	Collagen triple helix repeat
InterPro	IPR001073	Complement C1q protein
InterPro	IPR006052	Tumour necrosis factor
InterPro	IPR008983	Tumour necrosis factor-like domain
Protein Ontology	PR:000004878	complement C1q subcomponent subunit C

References

(Earliest) J:3065 Petry F, et al., Isolation, sequence analysis and characterization of cDNA clones coding for the C chain of mouse C1q. Sequence similarity of complement subcomponent C1q, collagen type VIII and type X and precerebellin. Eur J Biochem. 1992 Oct 1;209(1):129-34
(Latest) J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
All references(31)

Other accession IDs

MGD-MRK-1698, MGI:2140252