Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BRAP
  • Mouse genes Brap
  • Rat genes Brap
  • Zfish genes brap
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Brap

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	BRAP	IPI	UniProtKB:Q7Z569	Human	PMID:14724641
Molecular Function	GO:0042802	identical protein binding	BRAP	IPI	UniProtKB:Q7Z569	Human	PMID:25820252
Molecular Function	GO:0008139	nuclear localization sequence binding	BRAP	IDA		Human	PMID:9497340
Molecular Function	GO:0005515	protein binding	BRAP	IPI	UniProtKB:P01112	Human	PMID:14724641
Molecular Function	GO:0005515	protein binding	BRAP	IPI	UniProtKB:O75969	Human	PMID:25820252
Molecular Function	GO:0005515	protein binding	BRAP	IPI	UniProtKB:Q9BW85	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BRAP	IPI	UniProtKB:P38398	Human	PMID:9497340
Molecular Function	GO:0005515	protein binding	Brap	IPI	UniProtKB:O88987	Mouse	MGI:MGI:5700472|PMID:25820252
Molecular Function	GO:0061630	ubiquitin protein ligase activity	BRAP	IDA		Human	PMID:14724641
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	BRAP	IDA		Human	PMID:14724641
Cellular Component	GO:0005737	cytoplasm	BRAP	IDA		Human	PMID:9497340
Cellular Component	GO:0005829	cytosol	BRAP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031965	nuclear membrane	BRAP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	BRAP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000151	ubiquitin ligase complex	BRAP	IDA		Human	PMID:14724641
Biological Process	GO:0000165	MAPK cascade	BRAP	IDA		Human	PMID:14724641
Biological Process	GO:0009968	negative regulation of signal transduction	BRAP	IDA		Human	PMID:14724641
Biological Process	GO:0016567	protein ubiquitination	BRAP	IDA		Human	PMID:14724641
Biological Process	GO:0007265	Ras protein signal transduction	BRAP	IDA		Human	PMID:14724641

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern