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Gene Ontology Browser
Term Detail
GO term:negative regulation of signal transduction
Synonym: down regulation of signal transduction
Synonym: down-regulation of signal transduction
Synonym: downregulation of signal transduction
Synonym: inhibition of signal transduction
Synonym: negative regulation of signaling pathway
Synonym: negative regulation of signalling pathway
GO id:GO:0009968
Alternate id: GO:0035467
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction.
Number of paths to term: 59

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-anegative regulation of biological process
                                is-anegative regulation of cellular process
                                        is-anegative regulation of cell communication
                                                is-anegative regulation of atrial cardiac muscle cell action potential +
                                                is-anegative regulation of AV node cell action potential +
                                                is-anegative regulation of BMP secretion +
                                                is-anegative regulation of cell communication by chemical coupling
                                                is-anegative regulation of cell communication by electrical coupling +
                                                is-anegative regulation of cellular response to amino acid starvation
                                                is-anegative regulation of cellular response to iron ion starvation
                                                is-anegative regulation of cellular response to nitrogen starvation
                                                is-anegative regulation of establishment of competence for transformation
                                                is-anegative regulation of hormone secretion +
                                                is-anegative regulation of signal transduction [GO:0009968] (995 genes, 1756 annotations)
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of acetylcholine-gated cation channel activity
                                                        is-anegative regulation of advanced glycation end-product receptor activity
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apolipoprotein A-I-mediated signaling pathway
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of corticotropin-releasing hormone receptor activity
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response +
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of excitatory postsynaptic potential
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway +
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of osmolarity-sensing cation channel activity
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of thyroid hormone receptor activity
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +
                                                is-anegative regulation of sorocarp spore cell differentiation
                                                is-anegative regulation of sorocarp stalk cell differentiation
                                                is-anegative regulation of synaptic transmission +
                                                is-anegative regulation of transmission of nerve impulse +
                                                is-anegative regulation of trichome patterning
                                                is-anegative regulation of Wnt protein secretion


obsolete Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-anegative regulation of biological process
                                is-anegative regulation of response to stimulus
                                        is-anegative regulation of cellular response to alkaline pH +
                                        is-anegative regulation of cellular response to caffeine
                                        is-anegative regulation of cellular response to growth factor stimulus +
                                        is-anegative regulation of cellular response to heat
                                        is-anegative regulation of cellular response to hypoxia +
                                        is-anegative regulation of cellular response to insulin stimulus +
                                        is-anegative regulation of cellular response to testosterone stimulus
                                        is-anegative regulation of cellular response to X-ray
                                        is-anegative regulation of cellular senescence
                                        is-anegative regulation of defense response +
                                        is-anegative regulation of detection of glucose
                                        is-anegative regulation of fear response +
                                        is-anegative regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus
                                        is-anegative regulation of filamentous growth of a population of unicellular organisms in response to heat
                                        is-anegative regulation of filamentous growth of a population of unicellular organisms in response to pH +
                                        is-anegative regulation of immune response +
                                        is-anegative regulation of insulin secretion involved in cellular response to glucose stimulus
                                        is-anegative regulation of long-day photoperiodism, flowering
                                        is-anegative regulation of mitochondrial unfolded protein response by negative regulation of transcription from RNA polymerase II promoter
                                        is-anegative regulation of mitophagy in response to mitochondrial depolarization +
                                        is-anegative regulation of muscle adaptation +
                                        is-anegative regulation of neuron projection regeneration +
                                        is-anegative regulation of peroxidase activity +
                                        is-anegative regulation of photomorphogenesis
                                        is-anegative regulation of production of miRNAs involved in gene silencing by miRNA +
                                        is-anegative regulation of production of siRNA involved in RNA interference
                                        is-anegative regulation of protein activation cascade +
                                        is-anegative regulation of response to acetate +
                                        is-anegative regulation of response to alcohol +
                                        is-anegative regulation of response to amylopectin
                                        is-anegative regulation of response to benzene
                                        is-anegative regulation of response to biotic stimulus +
                                        is-anegative regulation of response to cycloalkane
                                        is-anegative regulation of response to cytokine stimulus +
                                        is-anegative regulation of response to DNA damage stimulus +
                                        is-anegative regulation of response to drug +
                                        is-anegative regulation of response to endoplasmic reticulum stress +
                                        is-anegative regulation of response to external stimulus +
                                        is-anegative regulation of response to formic acid
                                        is-anegative regulation of response to furfural
                                        is-anegative regulation of response to gamma radiation
                                        is-anegative regulation of response to oxidative stress +
                                        is-anegative regulation of response to pullulan
                                        is-anegative regulation of response to salt stress +
                                        is-anegative regulation of response to toluene
                                        is-anegative regulation of response to water deprivation
                                        is-anegative regulation of response to wounding +
                                        is-anegative regulation of shade avoidance
                                        is-anegative regulation of short-day photoperiodism, flowering
                                        is-anegative regulation of signal transduction [GO:0009968] (995 genes, 1756 annotations)
                                                is-aextracellular negative regulation of signal transduction +
                                                is-ametarhodopsin inactivation
                                                is-anegative adaptation of signaling pathway +
                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                is-anegative regulation of acetylcholine-gated cation channel activity
                                                is-anegative regulation of advanced glycation end-product receptor activity
                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                is-anegative regulation of apolipoprotein A-I-mediated signaling pathway
                                                is-anegative regulation of apoptotic signaling pathway +
                                                is-anegative regulation of auxin mediated signaling pathway
                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                is-anegative regulation of CD40 signaling pathway
                                                is-anegative regulation of corticotropin-releasing hormone receptor activity
                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                is-anegative regulation of endoplasmic reticulum unfolded protein response +
                                                is-anegative regulation of ephrin receptor signaling pathway
                                                is-anegative regulation of ERBB signaling pathway +
                                                is-anegative regulation of excitatory postsynaptic potential
                                                is-anegative regulation of Fas signaling pathway
                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                is-anegative regulation of glucose mediated signaling pathway
                                                is-anegative regulation of glutamate receptor signaling pathway +
                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                is-anegative regulation of insulin receptor signaling pathway +
                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                is-anegative regulation of integrin-mediated signaling pathway
                                                is-anegative regulation of intracellular signal transduction +
                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                is-anegative regulation of nerve growth factor receptor activity
                                                is-anegative regulation of netrin-activated signaling pathway
                                                is-anegative regulation of neuronal signal transduction
                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                is-anegative regulation of Notch signaling pathway +
                                                is-anegative regulation of osmolarity-sensing cation channel activity
                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                is-anegative regulation of red or far-red light signaling pathway
                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                is-anegative regulation of Roundabout signaling pathway +
                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                is-anegative regulation of sevenless signaling pathway
                                                is-anegative regulation of signal transduction by receptor internalization +
                                                is-anegative regulation of signal transduction in absence of ligand +
                                                is-anegative regulation of signal transduction in response to host +
                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                is-anegative regulation of smoothened signaling pathway +
                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                is-anegative regulation of SREBP signaling pathway +
                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                is-anegative regulation of thyroid hormone receptor activity
                                                is-anegative regulation of Toll signaling pathway
                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                is-anegative regulation of Wnt signaling pathway +
                                                is-atermination of signal transduction +
                                        is-anegative regulation of stress response to copper ion
                                        is-anegative regulation of toluene catabolic process
                                        is-anegative regulation of vernalization response


obsolete Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-anegative regulation of biological process
                                is-anegative regulation of signaling
                                        is-anegative regulation of BMP secretion +
                                        is-anegative regulation of cardiac conduction +
                                        is-anegative regulation of hormone secretion +
                                        is-anegative regulation of receptor recycling
                                        is-anegative regulation of signal transduction [GO:0009968] (995 genes, 1756 annotations)
                                                is-aextracellular negative regulation of signal transduction +
                                                is-ametarhodopsin inactivation
                                                is-anegative adaptation of signaling pathway +
                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                is-anegative regulation of acetylcholine-gated cation channel activity
                                                is-anegative regulation of advanced glycation end-product receptor activity
                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                is-anegative regulation of apolipoprotein A-I-mediated signaling pathway
                                                is-anegative regulation of apoptotic signaling pathway +
                                                is-anegative regulation of auxin mediated signaling pathway
                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                is-anegative regulation of CD40 signaling pathway
                                                is-anegative regulation of corticotropin-releasing hormone receptor activity
                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                is-anegative regulation of endoplasmic reticulum unfolded protein response +
                                                is-anegative regulation of ephrin receptor signaling pathway
                                                is-anegative regulation of ERBB signaling pathway +
                                                is-anegative regulation of excitatory postsynaptic potential
                                                is-anegative regulation of Fas signaling pathway
                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                is-anegative regulation of glucose mediated signaling pathway
                                                is-anegative regulation of glutamate receptor signaling pathway +
                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                is-anegative regulation of insulin receptor signaling pathway +
                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                is-anegative regulation of integrin-mediated signaling pathway
                                                is-anegative regulation of intracellular signal transduction +
                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                is-anegative regulation of nerve growth factor receptor activity
                                                is-anegative regulation of netrin-activated signaling pathway
                                                is-anegative regulation of neuronal signal transduction
                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                is-anegative regulation of Notch signaling pathway +
                                                is-anegative regulation of osmolarity-sensing cation channel activity
                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                is-anegative regulation of red or far-red light signaling pathway
                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                is-anegative regulation of Roundabout signaling pathway +
                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                is-anegative regulation of sevenless signaling pathway
                                                is-anegative regulation of signal transduction by receptor internalization +
                                                is-anegative regulation of signal transduction in absence of ligand +
                                                is-anegative regulation of signal transduction in response to host +
                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                is-anegative regulation of smoothened signaling pathway +
                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                is-anegative regulation of SREBP signaling pathway +
                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                is-anegative regulation of thyroid hormone receptor activity
                                                is-anegative regulation of Toll signaling pathway
                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                is-anegative regulation of Wnt signaling pathway +
                                                is-atermination of signal transduction +
                                        is-anegative regulation of synaptic transmission +
                                        is-anegative regulation of transmission of nerve impulse +
                                        is-anegative regulation of trichome patterning
                                        is-anegative regulation of Wnt protein secretion


obsolete Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of cellular process
                                is-anegative regulation of cellular process
                                        is-anegative regulation of cell communication
                                                is-anegative regulation of atrial cardiac muscle cell action potential +
                                                is-anegative regulation of AV node cell action potential +
                                                is-anegative regulation of BMP secretion +
                                                is-anegative regulation of cell communication by chemical coupling
                                                is-anegative regulation of cell communication by electrical coupling +
                                                is-anegative regulation of cellular response to amino acid starvation
                                                is-anegative regulation of cellular response to iron ion starvation
                                                is-anegative regulation of cellular response to nitrogen starvation
                                                is-anegative regulation of establishment of competence for transformation
                                                is-anegative regulation of hormone secretion +
                                                is-anegative regulation of signal transduction [GO:0009968] (995 genes, 1756 annotations)
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of acetylcholine-gated cation channel activity
                                                        is-anegative regulation of advanced glycation end-product receptor activity
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apolipoprotein A-I-mediated signaling pathway
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of corticotropin-releasing hormone receptor activity
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response +
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of excitatory postsynaptic potential
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway +
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of osmolarity-sensing cation channel activity
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of thyroid hormone receptor activity
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +
                                                is-anegative regulation of sorocarp spore cell differentiation
                                                is-anegative regulation of sorocarp stalk cell differentiation
                                                is-anegative regulation of synaptic transmission +
                                                is-anegative regulation of transmission of nerve impulse +
                                                is-anegative regulation of trichome patterning
                                                is-anegative regulation of Wnt protein secretion


obsolete Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of cellular process
                                is-aregulation of cell communication
                                        is-anegative regulation of cell communication
                                                is-anegative regulation of atrial cardiac muscle cell action potential +
                                                is-anegative regulation of AV node cell action potential +
                                                is-anegative regulation of BMP secretion +
                                                is-anegative regulation of cell communication by chemical coupling
                                                is-anegative regulation of cell communication by electrical coupling +
                                                is-anegative regulation of cellular response to amino acid starvation
                                                is-anegative regulation of cellular response to iron ion starvation
                                                is-anegative regulation of cellular response to nitrogen starvation
                                                is-anegative regulation of establishment of competence for transformation
                                                is-anegative regulation of hormone secretion +
                                                is-anegative regulation of signal transduction [GO:0009968] (995 genes, 1756 annotations)
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of acetylcholine-gated cation channel activity
                                                        is-anegative regulation of advanced glycation end-product receptor activity
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apolipoprotein A-I-mediated signaling pathway
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of corticotropin-releasing hormone receptor activity
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response +
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of excitatory postsynaptic potential
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway +
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of osmolarity-sensing cation channel activity
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of thyroid hormone receptor activity
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +
                                                is-anegative regulation of sorocarp spore cell differentiation
                                                is-anegative regulation of sorocarp stalk cell differentiation
                                                is-anegative regulation of synaptic transmission +
                                                is-anegative regulation of transmission of nerve impulse +
                                                is-anegative regulation of trichome patterning
                                                is-anegative regulation of Wnt protein secretion


obsolete Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of cellular process
                                is-aregulation of cell communication
                                        is-aregulation of signal transduction
                                                is-aadaptation of signaling pathway +
                                                is-aextracellular regulation of signal transduction +
                                                is-amodulation of excitatory postsynaptic potential +
                                                is-amodulation of inhibitory postsynaptic potential +
                                                is-amodulation of signal transduction in other organism +
                                                is-anegative regulation of signal transduction [GO:0009968] (995 genes, 1756 annotations)
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of acetylcholine-gated cation channel activity
                                                        is-anegative regulation of advanced glycation end-product receptor activity
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apolipoprotein A-I-mediated signaling pathway
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of corticotropin-releasing hormone receptor activity
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response +
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of excitatory postsynaptic potential
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway +
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of osmolarity-sensing cation channel activity
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of thyroid hormone receptor activity
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +
                                                is-apositive regulation of signal transduction +
                                                is-aregulation of abscisic acid-activated signaling pathway +
                                                is-aregulation of anti-Mullerian hormone signaling pathway +
                                                is-aregulation of antigen receptor-mediated signaling pathway +
                                                is-aregulation of apolipoprotein A-I-mediated signaling pathway +
                                                is-aregulation of apoptotic signaling pathway +
                                                is-aregulation of auxin mediated signaling pathway +
                                                is-aregulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                is-aregulation of brassinosteroid mediated signaling pathway +
                                                is-aregulation of CD40 signaling pathway +
                                                is-aregulation of cytokine-mediated signaling pathway +
                                                is-aregulation of cytokinin-activated signaling pathway +
                                                is-aregulation of endoplasmic reticulum unfolded protein response +
                                                is-aregulation of ephrin receptor signaling pathway +
                                                is-aregulation of ERBB signaling pathway +
                                                is-aregulation of Fas signaling pathway +
                                                is-aregulation of Fc receptor mediated stimulatory signaling pathway +
                                                is-aregulation of fibroblast growth factor receptor signaling pathway +
                                                is-aregulation of G-protein coupled receptor protein signaling pathway +
                                                is-aregulation of gibberellic acid mediated signaling pathway +
                                                is-aregulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                                is-aregulation of glucocorticoid mediated signaling pathway +
                                                is-aregulation of glucose mediated signaling pathway +
                                                is-aregulation of glutamate receptor signaling pathway +
                                                is-aregulation of growth hormone receptor signaling pathway +
                                                is-aregulation of hepatocyte growth factor receptor signaling pathway +
                                                is-aregulation of hypoxia-inducible factor-1alpha signaling pathway +
                                                is-aregulation of insulin receptor signaling pathway +
                                                is-aregulation of insulin-like growth factor receptor signaling pathway +
                                                is-aregulation of integrin-mediated signaling pathway +
                                                is-aregulation of intracellular signal transduction +
                                                is-aregulation of intracellular steroid hormone receptor signaling pathway +
                                                is-aregulation of jasmonic acid mediated signaling pathway
                                                is-aregulation of lipopolysaccharide-mediated signaling pathway +
                                                is-aregulation of netrin-activated signaling pathway +
                                                is-aregulation of neuronal signal transduction +
                                                is-aregulation of neurotrophin TRK receptor signaling pathway +
                                                is-aregulation of Notch signaling pathway +
                                                is-aregulation of peptidoglycan recognition protein signaling pathway +
                                                is-aregulation of peroxisome proliferator activated receptor signaling pathway +
                                                is-aregulation of platelet-derived growth factor receptor signaling pathway +
                                                is-aregulation of receptor activity +
                                                is-aregulation of red or far-red light signaling pathway +
                                                is-aregulation of retinoic acid receptor signaling pathway +
                                                is-aregulation of Roundabout signaling pathway +
                                                is-aregulation of salicylic acid mediated signaling pathway +
                                                is-aregulation of semaphorin-plexin signaling pathway +
                                                is-aregulation of sevenless signaling pathway +
                                                is-aregulation of signal transduction by receptor internalization +
                                                is-aregulation of signal transduction in response to host +
                                                is-aregulation of signal transduction involved in conjugation with cellular fusion +
                                                is-aregulation of smoothened signaling pathway +
                                                is-aregulation of sphingolipid mediated signaling pathway +
                                                is-aregulation of SREBP signaling pathway +
                                                is-aregulation of thyroid hormone mediated signaling pathway +
                                                is-aregulation of Toll signaling pathway +
                                                is-aregulation of toll-like receptor signaling pathway +
                                                is-aregulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                is-aregulation of vascular endothelial growth factor receptor signaling pathway +
                                                is-aregulation of vascular endothelial growth factor signaling pathway +
                                                is-aregulation of vitamin D receptor signaling pathway +
                                                is-aregulation of Wnt signaling pathway +
                                                is-asignal clustering
                                                is-asignal complex assembly


obsolete Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-aapoptotic signaling pathway +
                                        is-abile acid signaling pathway +
                                        is-acalmodulin dependent kinase signaling pathway +
                                        is-acarbohydrate mediated signaling +
                                        is-acell surface receptor signaling pathway +
                                        is-achloroplast-nucleus signaling pathway
                                        is-adefense response signaling pathway, resistance gene-dependent
                                        is-adefense response signaling pathway, resistance gene-independent
                                        is-aendoplasmic reticulum unfolded protein response +
                                        is-aER-nucleus signaling pathway +
                                        is-aG-protein coupled receptor signaling pathway +
                                        is-ahormone-mediated signaling pathway +
                                        is-ahydrogen peroxide mediated signaling pathway +
                                        is-ahypoxia-inducible factor-1alpha signaling pathway +
                                        is-aimmune response-regulating signaling pathway +
                                        is-aintracellular receptor signaling pathway +
                                        is-aintracellular signal transduction +
                                        is-alipoprotein particle mediated signaling +
                                        is-amitochondria-nucleus signaling pathway
                                        is-anecroptotic signaling pathway
                                        negatively-regulatesnegative regulation of signal transduction [GO:0009968] (995 genes, 1756 annotations)
                                                is-aextracellular negative regulation of signal transduction +
                                                is-ametarhodopsin inactivation
                                                is-anegative adaptation of signaling pathway +
                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                is-anegative regulation of acetylcholine-gated cation channel activity
                                                is-anegative regulation of advanced glycation end-product receptor activity
                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                is-anegative regulation of apolipoprotein A-I-mediated signaling pathway
                                                is-anegative regulation of apoptotic signaling pathway +
                                                is-anegative regulation of auxin mediated signaling pathway
                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                is-anegative regulation of CD40 signaling pathway
                                                is-anegative regulation of corticotropin-releasing hormone receptor activity
                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                is-anegative regulation of endoplasmic reticulum unfolded protein response +
                                                is-anegative regulation of ephrin receptor signaling pathway
                                                is-anegative regulation of ERBB signaling pathway +
                                                is-anegative regulation of excitatory postsynaptic potential
                                                is-anegative regulation of Fas signaling pathway
                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                is-anegative regulation of glucose mediated signaling pathway
                                                is-anegative regulation of glutamate receptor signaling pathway +
                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                is-anegative regulation of insulin receptor signaling pathway +
                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                is-anegative regulation of integrin-mediated signaling pathway
                                                is-anegative regulation of intracellular signal transduction +
                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                is-anegative regulation of nerve growth factor receptor activity
                                                is-anegative regulation of netrin-activated signaling pathway
                                                is-anegative regulation of neuronal signal transduction
                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                is-anegative regulation of Notch signaling pathway +
                                                is-anegative regulation of osmolarity-sensing cation channel activity
                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                is-anegative regulation of red or far-red light signaling pathway
                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                is-anegative regulation of Roundabout signaling pathway +
                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                is-anegative regulation of sevenless signaling pathway
                                                is-anegative regulation of signal transduction by receptor internalization +
                                                is-anegative regulation of signal transduction in absence of ligand +
                                                is-anegative regulation of signal transduction in response to host +
                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                is-anegative regulation of smoothened signaling pathway +
                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                is-anegative regulation of SREBP signaling pathway +
                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                is-anegative regulation of thyroid hormone receptor activity
                                                is-anegative regulation of Toll signaling pathway
                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                is-anegative regulation of Wnt signaling pathway +
                                                is-atermination of signal transduction +
                                        negatively-regulatesnegative regulation of signal transduction by receptor internalization +
                                        is-aneuronal signal transduction +
                                        is-aosmosensory signaling pathway +
                                        is-aphototransduction +
                                        positively-regulatespositive regulation of signal transduction +
                                        positively-regulatespositive regulation of signal transduction by receptor internalization +
                                        is-apostsynaptic signal transduction +
                                        is-apresynaptic signal transduction +
                                        is-ared or far-red light signaling pathway +
                                        is-aregulation of blood pressure by chemoreceptor signaling pathway
                                        is-aregulation of floral organ abscission by signal transduction +
                                        regulatesregulation of signal transduction +
                                        regulatesregulation of signal transduction by receptor internalization +
                                        is-asalicylic acid mediated signaling pathway +
                                        is-asignal transduction by conformational transition
                                        is-asignal transduction by protein phosphorylation +
                                        is-asignal transduction in absence of ligand +
                                        is-asignal transduction involved in cellular response to ammonium ion +
                                        is-asignal transduction involved in conjugation with cellular fusion +
                                        is-asignal transduction involved in Dma1-dependent checkpoint
                                        is-asignal transduction involved in filamentous growth
                                        is-asignal transduction involved in morphogenesis checkpoint
                                        is-asignal transduction involved in regulation of aerobic respiration
                                        is-asignal transduction involved in regulation of gene expression
                                        is-aSMAD protein signal transduction
                                        is-asphingolipid mediated signaling pathway +


obsolete Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of cellular process
                                is-asignal transduction
                                        regulatesregulation of signal transduction
                                                is-aadaptation of signaling pathway +
                                                is-aextracellular regulation of signal transduction +
                                                is-amodulation of excitatory postsynaptic potential +
                                                is-amodulation of inhibitory postsynaptic potential +
                                                is-amodulation of signal transduction in other organism +
                                                is-anegative regulation of signal transduction [GO:0009968] (995 genes, 1756 annotations)
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of acetylcholine-gated cation channel activity
                                                        is-anegative regulation of advanced glycation end-product receptor activity
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apolipoprotein A-I-mediated signaling pathway
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of corticotropin-releasing hormone receptor activity
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response +
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of excitatory postsynaptic potential
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway +
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of osmolarity-sensing cation channel activity
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of thyroid hormone receptor activity
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +
                                                is-apositive regulation of signal transduction +
                                                is-aregulation of abscisic acid-activated signaling pathway +
                                                is-aregulation of anti-Mullerian hormone signaling pathway +
                                                is-aregulation of antigen receptor-mediated signaling pathway +
                                                is-aregulation of apolipoprotein A-I-mediated signaling pathway +
                                                is-aregulation of apoptotic signaling pathway +
                                                is-aregulation of auxin mediated signaling pathway +
                                                is-aregulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                is-aregulation of brassinosteroid mediated signaling pathway +
                                                is-aregulation of CD40 signaling pathway +
                                                is-aregulation of cytokine-mediated signaling pathway +
                                                is-aregulation of cytokinin-activated signaling pathway +
                                                is-aregulation of endoplasmic reticulum unfolded protein response +
                                                is-aregulation of ephrin receptor signaling pathway +
                                                is-aregulation of ERBB signaling pathway +
                                                is-aregulation of Fas signaling pathway +
                                                is-aregulation of Fc receptor mediated stimulatory signaling pathway +
                                                is-aregulation of fibroblast growth factor receptor signaling pathway +
                                                is-aregulation of G-protein coupled receptor protein signaling pathway +
                                                is-aregulation of gibberellic acid mediated signaling pathway +
                                                is-aregulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                                is-aregulation of glucocorticoid mediated signaling pathway +
                                                is-aregulation of glucose mediated signaling pathway +
                                                is-aregulation of glutamate receptor signaling pathway +
                                                is-aregulation of growth hormone receptor signaling pathway +
                                                is-aregulation of hepatocyte growth factor receptor signaling pathway +
                                                is-aregulation of hypoxia-inducible factor-1alpha signaling pathway +
                                                is-aregulation of insulin receptor signaling pathway +
                                                is-aregulation of insulin-like growth factor receptor signaling pathway +
                                                is-aregulation of integrin-mediated signaling pathway +
                                                is-aregulation of intracellular signal transduction +
                                                is-aregulation of intracellular steroid hormone receptor signaling pathway +
                                                is-aregulation of jasmonic acid mediated signaling pathway
                                                is-aregulation of lipopolysaccharide-mediated signaling pathway +
                                                is-aregulation of netrin-activated signaling pathway +
                                                is-aregulation of neuronal signal transduction +
                                                is-aregulation of neurotrophin TRK receptor signaling pathway +
                                                is-aregulation of Notch signaling pathway +
                                                is-aregulation of peptidoglycan recognition protein signaling pathway +
                                                is-aregulation of peroxisome proliferator activated receptor signaling pathway +
                                                is-aregulation of platelet-derived growth factor receptor signaling pathway +
                                                is-aregulation of receptor activity +
                                                is-aregulation of red or far-red light signaling pathway +
                                                is-aregulation of retinoic acid receptor signaling pathway +
                                                is-aregulation of Roundabout signaling pathway +
                                                is-aregulation of salicylic acid mediated signaling pathway +
                                                is-aregulation of semaphorin-plexin signaling pathway +
                                                is-aregulation of sevenless signaling pathway +
                                                is-aregulation of signal transduction by receptor internalization +
                                                is-aregulation of signal transduction in response to host +
                                                is-aregulation of signal transduction involved in conjugation with cellular fusion +
                                                is-aregulation of smoothened signaling pathway +
                                                is-aregulation of sphingolipid mediated signaling pathway +
                                                is-aregulation of SREBP signaling pathway +
                                                is-aregulation of thyroid hormone mediated signaling pathway +
                                                is-aregulation of Toll signaling pathway +
                                                is-aregulation of toll-like receptor signaling pathway +
                                                is-aregulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                is-aregulation of vascular endothelial growth factor receptor signaling pathway +
                                                is-aregulation of vascular endothelial growth factor signaling pathway +
                                                is-aregulation of vitamin D receptor signaling pathway +
                                                is-aregulation of Wnt signaling pathway +
                                                is-asignal clustering
                                                is-asignal complex assembly


obsolete Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of response to stimulus
                                is-anegative regulation of response to stimulus
                                        is-anegative regulation of cellular response to alkaline pH +
                                        is-anegative regulation of cellular response to caffeine
                                        is-anegative regulation of cellular response to growth factor stimulus +
                                        is-anegative regulation of cellular response to heat
                                        is-anegative regulation of cellular response to hypoxia +
                                        is-anegative regulation of cellular response to insulin stimulus +
                                        is-anegative regulation of cellular response to testosterone stimulus
                                        is-anegative regulation of cellular response to X-ray
                                        is-anegative regulation of cellular senescence
                                        is-anegative regulation of defense response +
                                        is-anegative regulation of detection of glucose
                                        is-anegative regulation of fear response +
                                        is-anegative regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus
                                        is-anegative regulation of filamentous growth of a population of unicellular organisms in response to heat
                                        is-anegative regulation of filamentous growth of a population of unicellular organisms in response to pH +
                                        is-anegative regulation of immune response +
                                        is-anegative regulation of insulin secretion involved in cellular response to glucose stimulus
                                        is-anegative regulation of long-day photoperiodism, flowering
                                        is-anegative regulation of mitochondrial unfolded protein response by negative regulation of transcription from RNA polymerase II promoter
                                        is-anegative regulation of mitophagy in response to mitochondrial depolarization +
                                        is-anegative regulation of muscle adaptation +
                                        is-anegative regulation of neuron projection regeneration +
                                        is-anegative regulation of peroxidase activity +
                                        is-anegative regulation of photomorphogenesis
                                        is-anegative regulation of production of miRNAs involved in gene silencing by miRNA +
                                        is-anegative regulation of production of siRNA involved in RNA interference
                                        is-anegative regulation of protein activation cascade +
                                        is-anegative regulation of response to acetate +
                                        is-anegative regulation of response to alcohol +
                                        is-anegative regulation of response to amylopectin
                                        is-anegative regulation of response to benzene
                                        is-anegative regulation of response to biotic stimulus +
                                        is-anegative regulation of response to cycloalkane
                                        is-anegative regulation of response to cytokine stimulus +
                                        is-anegative regulation of response to DNA damage stimulus +
                                        is-anegative regulation of response to drug +
                                        is-anegative regulation of response to endoplasmic reticulum stress +
                                        is-anegative regulation of response to external stimulus +
                                        is-anegative regulation of response to formic acid
                                        is-anegative regulation of response to furfural
                                        is-anegative regulation of response to gamma radiation
                                        is-anegative regulation of response to oxidative stress +
                                        is-anegative regulation of response to pullulan
                                        is-anegative regulation of response to salt stress +
                                        is-anegative regulation of response to toluene
                                        is-anegative regulation of response to water deprivation
                                        is-anegative regulation of response to wounding +
                                        is-anegative regulation of shade avoidance
                                        is-anegative regulation of short-day photoperiodism, flowering
                                        is-anegative regulation of signal transduction [GO:0009968] (995 genes, 1756 annotations)
                                                is-aextracellular negative regulation of signal transduction +
                                                is-ametarhodopsin inactivation
                                                is-anegative adaptation of signaling pathway +
                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                is-anegative regulation of acetylcholine-gated cation channel activity
                                                is-anegative regulation of advanced glycation end-product receptor activity
                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                is-anegative regulation of apolipoprotein A-I-mediated signaling pathway
                                                is-anegative regulation of apoptotic signaling pathway +
                                                is-anegative regulation of auxin mediated signaling pathway
                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                is-anegative regulation of CD40 signaling pathway
                                                is-anegative regulation of corticotropin-releasing hormone receptor activity
                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                is-anegative regulation of endoplasmic reticulum unfolded protein response +
                                                is-anegative regulation of ephrin receptor signaling pathway
                                                is-anegative regulation of ERBB signaling pathway +
                                                is-anegative regulation of excitatory postsynaptic potential
                                                is-anegative regulation of Fas signaling pathway
                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                is-anegative regulation of glucose mediated signaling pathway
                                                is-anegative regulation of glutamate receptor signaling pathway +
                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                is-anegative regulation of insulin receptor signaling pathway +
                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                is-anegative regulation of integrin-mediated signaling pathway
                                                is-anegative regulation of intracellular signal transduction +
                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                is-anegative regulation of nerve growth factor receptor activity
                                                is-anegative regulation of netrin-activated signaling pathway
                                                is-anegative regulation of neuronal signal transduction
                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                is-anegative regulation of Notch signaling pathway +
                                                is-anegative regulation of osmolarity-sensing cation channel activity
                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                is-anegative regulation of red or far-red light signaling pathway
                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                is-anegative regulation of Roundabout signaling pathway +
                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                is-anegative regulation of sevenless signaling pathway
                                                is-anegative regulation of signal transduction by receptor internalization +
                                                is-anegative regulation of signal transduction in absence of ligand +
                                                is-anegative regulation of signal transduction in response to host +
                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                is-anegative regulation of smoothened signaling pathway +
                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                is-anegative regulation of SREBP signaling pathway +
                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                is-anegative regulation of thyroid hormone receptor activity
                                                is-anegative regulation of Toll signaling pathway
                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                is-anegative regulation of Wnt signaling pathway +
                                                is-atermination of signal transduction +
                                        is-anegative regulation of stress response to copper ion
                                        is-anegative regulation of toluene catabolic process
                                        is-anegative regulation of vernalization response


obsolete Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of response to stimulus
                                is-aregulation of signal transduction
                                        is-aadaptation of signaling pathway +
                                        is-aextracellular regulation of signal transduction +
                                        is-amodulation of excitatory postsynaptic potential +
                                        is-amodulation of inhibitory postsynaptic potential +
                                        is-amodulation of signal transduction in other organism +
                                        is-anegative regulation of signal transduction [GO:0009968] (995 genes, 1756 annotations)
                                                is-aextracellular negative regulation of signal transduction +
                                                is-ametarhodopsin inactivation
                                                is-anegative adaptation of signaling pathway +
                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                is-anegative regulation of acetylcholine-gated cation channel activity
                                                is-anegative regulation of advanced glycation end-product receptor activity
                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                is-anegative regulation of apolipoprotein A-I-mediated signaling pathway
                                                is-anegative regulation of apoptotic signaling pathway +
                                                is-anegative regulation of auxin mediated signaling pathway
                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                is-anegative regulation of CD40 signaling pathway
                                                is-anegative regulation of corticotropin-releasing hormone receptor activity
                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                is-anegative regulation of endoplasmic reticulum unfolded protein response +
                                                is-anegative regulation of ephrin receptor signaling pathway
                                                is-anegative regulation of ERBB signaling pathway +
                                                is-anegative regulation of excitatory postsynaptic potential
                                                is-anegative regulation of Fas signaling pathway
                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                is-anegative regulation of glucose mediated signaling pathway
                                                is-anegative regulation of glutamate receptor signaling pathway +
                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                is-anegative regulation of insulin receptor signaling pathway +
                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                is-anegative regulation of integrin-mediated signaling pathway
                                                is-anegative regulation of intracellular signal transduction +
                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                is-anegative regulation of nerve growth factor receptor activity
                                                is-anegative regulation of netrin-activated signaling pathway
                                                is-anegative regulation of neuronal signal transduction
                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                is-anegative regulation of Notch signaling pathway +
                                                is-anegative regulation of osmolarity-sensing cation channel activity
                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                is-anegative regulation of red or far-red light signaling pathway
                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                is-anegative regulation of Roundabout signaling pathway +
                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                is-anegative regulation of sevenless signaling pathway
                                                is-anegative regulation of signal transduction by receptor internalization +
                                                is-anegative regulation of signal transduction in absence of ligand +
                                                is-anegative regulation of signal transduction in response to host +
                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                is-anegative regulation of smoothened signaling pathway +
                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                is-anegative regulation of SREBP signaling pathway +
                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                is-anegative regulation of thyroid hormone receptor activity
                                                is-anegative regulation of Toll signaling pathway
                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                is-anegative regulation of Wnt signaling pathway +
                                                is-atermination of signal transduction +
                                        is-apositive regulation of signal transduction +
                                        is-aregulation of abscisic acid-activated signaling pathway +
                                        is-aregulation of anti-Mullerian hormone signaling pathway +
                                        is-aregulation of antigen receptor-mediated signaling pathway +
                                        is-aregulation of apolipoprotein A-I-mediated signaling pathway +
                                        is-aregulation of apoptotic signaling pathway +
                                        is-aregulation of auxin mediated signaling pathway +
                                        is-aregulation of brain-derived neurotrophic factor receptor signaling pathway +
                                        is-aregulation of brassinosteroid mediated signaling pathway +
                                        is-aregulation of CD40 signaling pathway +
                                        is-aregulation of cytokine-mediated signaling pathway +
                                        is-aregulation of cytokinin-activated signaling pathway +
                                        is-aregulation of endoplasmic reticulum unfolded protein response +
                                        is-aregulation of ephrin receptor signaling pathway +
                                        is-aregulation of ERBB signaling pathway +
                                        is-aregulation of Fas signaling pathway +
                                        is-aregulation of Fc receptor mediated stimulatory signaling pathway +
                                        is-aregulation of fibroblast growth factor receptor signaling pathway +
                                        is-aregulation of G-protein coupled receptor protein signaling pathway +
                                        is-aregulation of gibberellic acid mediated signaling pathway +
                                        is-aregulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                        is-aregulation of glucocorticoid mediated signaling pathway +
                                        is-aregulation of glucose mediated signaling pathway +
                                        is-aregulation of glutamate receptor signaling pathway +
                                        is-aregulation of growth hormone receptor signaling pathway +
                                        is-aregulation of hepatocyte growth factor receptor signaling pathway +
                                        is-aregulation of hypoxia-inducible factor-1alpha signaling pathway +
                                        is-aregulation of insulin receptor signaling pathway +
                                        is-aregulation of insulin-like growth factor receptor signaling pathway +
                                        is-aregulation of integrin-mediated signaling pathway +
                                        is-aregulation of intracellular signal transduction +
                                        is-aregulation of intracellular steroid hormone receptor signaling pathway +
                                        is-aregulation of jasmonic acid mediated signaling pathway
                                        is-aregulation of lipopolysaccharide-mediated signaling pathway +
                                        is-aregulation of netrin-activated signaling pathway +
                                        is-aregulation of neuronal signal transduction +
                                        is-aregulation of neurotrophin TRK receptor signaling pathway +
                                        is-aregulation of Notch signaling pathway +
                                        is-aregulation of peptidoglycan recognition protein signaling pathway +
                                        is-aregulation of peroxisome proliferator activated receptor signaling pathway +
                                        is-aregulation of platelet-derived growth factor receptor signaling pathway +
                                        is-aregulation of receptor activity +
                                        is-aregulation of red or far-red light signaling pathway +
                                        is-aregulation of retinoic acid receptor signaling pathway +
                                        is-aregulation of Roundabout signaling pathway +
                                        is-aregulation of salicylic acid mediated signaling pathway +
                                        is-aregulation of semaphorin-plexin signaling pathway +
                                        is-aregulation of sevenless signaling pathway +
                                        is-aregulation of signal transduction by receptor internalization +
                                        is-aregulation of signal transduction in response to host +
                                        is-aregulation of signal transduction involved in conjugation with cellular fusion +
                                        is-aregulation of smoothened signaling pathway +
                                        is-aregulation of sphingolipid mediated signaling pathway +
                                        is-aregulation of SREBP signaling pathway +
                                        is-aregulation of thyroid hormone mediated signaling pathway +
                                        is-aregulation of Toll signaling pathway +
                                        is-aregulation of toll-like receptor signaling pathway +
                                        is-aregulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                        is-aregulation of vascular endothelial growth factor receptor signaling pathway +
                                        is-aregulation of vascular endothelial growth factor signaling pathway +
                                        is-aregulation of vitamin D receptor signaling pathway +
                                        is-aregulation of Wnt signaling pathway +
                                        is-asignal clustering
                                        is-asignal complex assembly


obsolete Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of signaling
                                is-anegative regulation of signaling
                                        is-anegative regulation of BMP secretion +
                                        is-anegative regulation of cardiac conduction +
                                        is-anegative regulation of hormone secretion +
                                        is-anegative regulation of receptor recycling
                                        is-anegative regulation of signal transduction [GO:0009968] (995 genes, 1756 annotations)
                                                is-aextracellular negative regulation of signal transduction +
                                                is-ametarhodopsin inactivation
                                                is-anegative adaptation of signaling pathway +
                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                is-anegative regulation of acetylcholine-gated cation channel activity
                                                is-anegative regulation of advanced glycation end-product receptor activity
                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                is-anegative regulation of apolipoprotein A-I-mediated signaling pathway
                                                is-anegative regulation of apoptotic signaling pathway +
                                                is-anegative regulation of auxin mediated signaling pathway
                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                is-anegative regulation of CD40 signaling pathway
                                                is-anegative regulation of corticotropin-releasing hormone receptor activity
                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                is-anegative regulation of endoplasmic reticulum unfolded protein response +
                                                is-anegative regulation of ephrin receptor signaling pathway
                                                is-anegative regulation of ERBB signaling pathway +
                                                is-anegative regulation of excitatory postsynaptic potential
                                                is-anegative regulation of Fas signaling pathway
                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                is-anegative regulation of glucose mediated signaling pathway
                                                is-anegative regulation of glutamate receptor signaling pathway +
                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                is-anegative regulation of insulin receptor signaling pathway +
                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                is-anegative regulation of integrin-mediated signaling pathway
                                                is-anegative regulation of intracellular signal transduction +
                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                is-anegative regulation of nerve growth factor receptor activity
                                                is-anegative regulation of netrin-activated signaling pathway
                                                is-anegative regulation of neuronal signal transduction
                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                is-anegative regulation of Notch signaling pathway +
                                                is-anegative regulation of osmolarity-sensing cation channel activity
                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                is-anegative regulation of red or far-red light signaling pathway
                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                is-anegative regulation of Roundabout signaling pathway +
                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                is-anegative regulation of sevenless signaling pathway
                                                is-anegative regulation of signal transduction by receptor internalization +
                                                is-anegative regulation of signal transduction in absence of ligand +
                                                is-anegative regulation of signal transduction in response to host +
                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                is-anegative regulation of smoothened signaling pathway +
                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                is-anegative regulation of SREBP signaling pathway +
                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                is-anegative regulation of thyroid hormone receptor activity
                                                is-anegative regulation of Toll signaling pathway
                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                is-anegative regulation of Wnt signaling pathway +
                                                is-atermination of signal transduction +
                                        is-anegative regulation of synaptic transmission +
                                        is-anegative regulation of transmission of nerve impulse +
                                        is-anegative regulation of trichome patterning
                                        is-anegative regulation of Wnt protein secretion


obsolete Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of signaling
                                is-aregulation of signal transduction
                                        is-aadaptation of signaling pathway +
                                        is-aextracellular regulation of signal transduction +
                                        is-amodulation of excitatory postsynaptic potential +
                                        is-amodulation of inhibitory postsynaptic potential +
                                        is-amodulation of signal transduction in other organism +
                                        is-anegative regulation of signal transduction [GO:0009968] (995 genes, 1756 annotations)
                                                is-aextracellular negative regulation of signal transduction +
                                                is-ametarhodopsin inactivation
                                                is-anegative adaptation of signaling pathway +
                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                is-anegative regulation of acetylcholine-gated cation channel activity
                                                is-anegative regulation of advanced glycation end-product receptor activity
                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                is-anegative regulation of apolipoprotein A-I-mediated signaling pathway
                                                is-anegative regulation of apoptotic signaling pathway +
                                                is-anegative regulation of auxin mediated signaling pathway
                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                is-anegative regulation of CD40 signaling pathway
                                                is-anegative regulation of corticotropin-releasing hormone receptor activity
                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                is-anegative regulation of endoplasmic reticulum unfolded protein response +
                                                is-anegative regulation of ephrin receptor signaling pathway
                                                is-anegative regulation of ERBB signaling pathway +
                                                is-anegative regulation of excitatory postsynaptic potential
                                                is-anegative regulation of Fas signaling pathway
                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                is-anegative regulation of glucose mediated signaling pathway
                                                is-anegative regulation of glutamate receptor signaling pathway +
                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                is-anegative regulation of insulin receptor signaling pathway +
                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                is-anegative regulation of integrin-mediated signaling pathway
                                                is-anegative regulation of intracellular signal transduction +
                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                is-anegative regulation of nerve growth factor receptor activity
                                                is-anegative regulation of netrin-activated signaling pathway
                                                is-anegative regulation of neuronal signal transduction
                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                is-anegative regulation of Notch signaling pathway +
                                                is-anegative regulation of osmolarity-sensing cation channel activity
                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                is-anegative regulation of red or far-red light signaling pathway
                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                is-anegative regulation of Roundabout signaling pathway +
                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                is-anegative regulation of sevenless signaling pathway
                                                is-anegative regulation of signal transduction by receptor internalization +
                                                is-anegative regulation of signal transduction in absence of ligand +
                                                is-anegative regulation of signal transduction in response to host +
                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                is-anegative regulation of smoothened signaling pathway +
                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                is-anegative regulation of SREBP signaling pathway +
                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                is-anegative regulation of thyroid hormone receptor activity
                                                is-anegative regulation of Toll signaling pathway
                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                is-anegative regulation of Wnt signaling pathway +
                                                is-atermination of signal transduction +
                                        is-apositive regulation of signal transduction +
                                        is-aregulation of abscisic acid-activated signaling pathway +
                                        is-aregulation of anti-Mullerian hormone signaling pathway +
                                        is-aregulation of antigen receptor-mediated signaling pathway +
                                        is-aregulation of apolipoprotein A-I-mediated signaling pathway +
                                        is-aregulation of apoptotic signaling pathway +
                                        is-aregulation of auxin mediated signaling pathway +
                                        is-aregulation of brain-derived neurotrophic factor receptor signaling pathway +
                                        is-aregulation of brassinosteroid mediated signaling pathway +
                                        is-aregulation of CD40 signaling pathway +
                                        is-aregulation of cytokine-mediated signaling pathway +
                                        is-aregulation of cytokinin-activated signaling pathway +
                                        is-aregulation of endoplasmic reticulum unfolded protein response +
                                        is-aregulation of ephrin receptor signaling pathway +
                                        is-aregulation of ERBB signaling pathway +
                                        is-aregulation of Fas signaling pathway +
                                        is-aregulation of Fc receptor mediated stimulatory signaling pathway +
                                        is-aregulation of fibroblast growth factor receptor signaling pathway +
                                        is-aregulation of G-protein coupled receptor protein signaling pathway +
                                        is-aregulation of gibberellic acid mediated signaling pathway +
                                        is-aregulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                        is-aregulation of glucocorticoid mediated signaling pathway +
                                        is-aregulation of glucose mediated signaling pathway +
                                        is-aregulation of glutamate receptor signaling pathway +
                                        is-aregulation of growth hormone receptor signaling pathway +
                                        is-aregulation of hepatocyte growth factor receptor signaling pathway +
                                        is-aregulation of hypoxia-inducible factor-1alpha signaling pathway +
                                        is-aregulation of insulin receptor signaling pathway +
                                        is-aregulation of insulin-like growth factor receptor signaling pathway +
                                        is-aregulation of integrin-mediated signaling pathway +
                                        is-aregulation of intracellular signal transduction +
                                        is-aregulation of intracellular steroid hormone receptor signaling pathway +
                                        is-aregulation of jasmonic acid mediated signaling pathway
                                        is-aregulation of lipopolysaccharide-mediated signaling pathway +
                                        is-aregulation of netrin-activated signaling pathway +
                                        is-aregulation of neuronal signal transduction +
                                        is-aregulation of neurotrophin TRK receptor signaling pathway +
                                        is-aregulation of Notch signaling pathway +
                                        is-aregulation of peptidoglycan recognition protein signaling pathway +
                                        is-aregulation of peroxisome proliferator activated receptor signaling pathway +
                                        is-aregulation of platelet-derived growth factor receptor signaling pathway +
                                        is-aregulation of receptor activity +
                                        is-aregulation of red or far-red light signaling pathway +
                                        is-aregulation of retinoic acid receptor signaling pathway +
                                        is-aregulation of Roundabout signaling pathway +
                                        is-aregulation of salicylic acid mediated signaling pathway +
                                        is-aregulation of semaphorin-plexin signaling pathway +
                                        is-aregulation of sevenless signaling pathway +
                                        is-aregulation of signal transduction by receptor internalization +
                                        is-aregulation of signal transduction in response to host +
                                        is-aregulation of signal transduction involved in conjugation with cellular fusion +
                                        is-aregulation of smoothened signaling pathway +
                                        is-aregulation of sphingolipid mediated signaling pathway +
                                        is-aregulation of SREBP signaling pathway +
                                        is-aregulation of thyroid hormone mediated signaling pathway +
                                        is-aregulation of Toll signaling pathway +
                                        is-aregulation of toll-like receptor signaling pathway +
                                        is-aregulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                        is-aregulation of vascular endothelial growth factor receptor signaling pathway +
                                        is-aregulation of vascular endothelial growth factor signaling pathway +
                                        is-aregulation of vitamin D receptor signaling pathway +
                                        is-aregulation of Wnt signaling pathway +
                                        is-asignal clustering
                                        is-asignal complex assembly


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                part-ofsignal transduction
                                        is-aapoptotic signaling pathway +
                                        is-abile acid signaling pathway +
                                        is-acalmodulin dependent kinase signaling pathway +
                                        is-acarbohydrate mediated signaling +
                                        is-acell surface receptor signaling pathway +
                                        is-achloroplast-nucleus signaling pathway
                                        is-adefense response signaling pathway, resistance gene-dependent
                                        is-adefense response signaling pathway, resistance gene-independent
                                        is-aendoplasmic reticulum unfolded protein response +
                                        is-aER-nucleus signaling pathway +
                                        is-aG-protein coupled receptor signaling pathway +
                                        is-ahormone-mediated signaling pathway +
                                        is-ahydrogen peroxide mediated signaling pathway +
                                        is-ahypoxia-inducible factor-1alpha signaling pathway +
                                        is-aimmune response-regulating signaling pathway +
                                        is-aintracellular receptor signaling pathway +
                                        is-aintracellular signal transduction +
                                        is-alipoprotein particle mediated signaling +
                                        is-amitochondria-nucleus signaling pathway
                                        is-anecroptotic signaling pathway
                                        negatively-regulatesnegative regulation of signal transduction [GO:0009968] (995 genes, 1756 annotations)
                                                is-aextracellular negative regulation of signal transduction +
                                                is-ametarhodopsin inactivation
                                                is-anegative adaptation of signaling pathway +
                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                is-anegative regulation of acetylcholine-gated cation channel activity
                                                is-anegative regulation of advanced glycation end-product receptor activity
                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                is-anegative regulation of apolipoprotein A-I-mediated signaling pathway
                                                is-anegative regulation of apoptotic signaling pathway +
                                                is-anegative regulation of auxin mediated signaling pathway
                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                is-anegative regulation of CD40 signaling pathway
                                                is-anegative regulation of corticotropin-releasing hormone receptor activity
                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                is-anegative regulation of endoplasmic reticulum unfolded protein response +
                                                is-anegative regulation of ephrin receptor signaling pathway
                                                is-anegative regulation of ERBB signaling pathway +
                                                is-anegative regulation of excitatory postsynaptic potential
                                                is-anegative regulation of Fas signaling pathway
                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                is-anegative regulation of glucose mediated signaling pathway
                                                is-anegative regulation of glutamate receptor signaling pathway +
                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                is-anegative regulation of insulin receptor signaling pathway +
                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                is-anegative regulation of integrin-mediated signaling pathway
                                                is-anegative regulation of intracellular signal transduction +
                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                is-anegative regulation of nerve growth factor receptor activity
                                                is-anegative regulation of netrin-activated signaling pathway
                                                is-anegative regulation of neuronal signal transduction
                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                is-anegative regulation of Notch signaling pathway +
                                                is-anegative regulation of osmolarity-sensing cation channel activity
                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                is-anegative regulation of red or far-red light signaling pathway
                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                is-anegative regulation of Roundabout signaling pathway +
                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                is-anegative regulation of sevenless signaling pathway
                                                is-anegative regulation of signal transduction by receptor internalization +
                                                is-anegative regulation of signal transduction in absence of ligand +
                                                is-anegative regulation of signal transduction in response to host +
                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                is-anegative regulation of smoothened signaling pathway +
                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                is-anegative regulation of SREBP signaling pathway +
                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                is-anegative regulation of thyroid hormone receptor activity
                                                is-anegative regulation of Toll signaling pathway
                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                is-anegative regulation of Wnt signaling pathway +
                                                is-atermination of signal transduction +
                                        negatively-regulatesnegative regulation of signal transduction by receptor internalization +
                                        is-aneuronal signal transduction +
                                        is-aosmosensory signaling pathway +
                                        is-aphototransduction +
                                        positively-regulatespositive regulation of signal transduction +
                                        positively-regulatespositive regulation of signal transduction by receptor internalization +
                                        is-apostsynaptic signal transduction +
                                        is-apresynaptic signal transduction +
                                        is-ared or far-red light signaling pathway +
                                        is-aregulation of blood pressure by chemoreceptor signaling pathway
                                        is-aregulation of floral organ abscission by signal transduction +
                                        regulatesregulation of signal transduction +
                                        regulatesregulation of signal transduction by receptor internalization +
                                        is-asalicylic acid mediated signaling pathway +
                                        is-asignal transduction by conformational transition
                                        is-asignal transduction by protein phosphorylation +
                                        is-asignal transduction in absence of ligand +
                                        is-asignal transduction involved in cellular response to ammonium ion +
                                        is-asignal transduction involved in conjugation with cellular fusion +
                                        is-asignal transduction involved in Dma1-dependent checkpoint
                                        is-asignal transduction involved in filamentous growth
                                        is-asignal transduction involved in morphogenesis checkpoint
                                        is-asignal transduction involved in regulation of aerobic respiration
                                        is-asignal transduction involved in regulation of gene expression
                                        is-aSMAD protein signal transduction
                                        is-asphingolipid mediated signaling pathway +


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                part-ofsignal transduction
                                        regulatesregulation of signal transduction
                                                is-aadaptation of signaling pathway +
                                                is-aextracellular regulation of signal transduction +
                                                is-amodulation of excitatory postsynaptic potential +
                                                is-amodulation of inhibitory postsynaptic potential +
                                                is-amodulation of signal transduction in other organism +
                                                is-anegative regulation of signal transduction [GO:0009968] (995 genes, 1756 annotations)
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of acetylcholine-gated cation channel activity
                                                        is-anegative regulation of advanced glycation end-product receptor activity
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apolipoprotein A-I-mediated signaling pathway
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of corticotropin-releasing hormone receptor activity
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response +
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of excitatory postsynaptic potential
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway +
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of osmolarity-sensing cation channel activity
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of thyroid hormone receptor activity
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +
                                                is-apositive regulation of signal transduction +
                                                is-aregulation of abscisic acid-activated signaling pathway +
                                                is-aregulation of anti-Mullerian hormone signaling pathway +
                                                is-aregulation of antigen receptor-mediated signaling pathway +
                                                is-aregulation of apolipoprotein A-I-mediated signaling pathway +
                                                is-aregulation of apoptotic signaling pathway +
                                                is-aregulation of auxin mediated signaling pathway +
                                                is-aregulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                is-aregulation of brassinosteroid mediated signaling pathway +
                                                is-aregulation of CD40 signaling pathway +
                                                is-aregulation of cytokine-mediated signaling pathway +
                                                is-aregulation of cytokinin-activated signaling pathway +
                                                is-aregulation of endoplasmic reticulum unfolded protein response +
                                                is-aregulation of ephrin receptor signaling pathway +
                                                is-aregulation of ERBB signaling pathway +
                                                is-aregulation of Fas signaling pathway +
                                                is-aregulation of Fc receptor mediated stimulatory signaling pathway +
                                                is-aregulation of fibroblast growth factor receptor signaling pathway +
                                                is-aregulation of G-protein coupled receptor protein signaling pathway +
                                                is-aregulation of gibberellic acid mediated signaling pathway +
                                                is-aregulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                                is-aregulation of glucocorticoid mediated signaling pathway +
                                                is-aregulation of glucose mediated signaling pathway +
                                                is-aregulation of glutamate receptor signaling pathway +
                                                is-aregulation of growth hormone receptor signaling pathway +
                                                is-aregulation of hepatocyte growth factor receptor signaling pathway +
                                                is-aregulation of hypoxia-inducible factor-1alpha signaling pathway +
                                                is-aregulation of insulin receptor signaling pathway +
                                                is-aregulation of insulin-like growth factor receptor signaling pathway +
                                                is-aregulation of integrin-mediated signaling pathway +
                                                is-aregulation of intracellular signal transduction +
                                                is-aregulation of intracellular steroid hormone receptor signaling pathway +
                                                is-aregulation of jasmonic acid mediated signaling pathway
                                                is-aregulation of lipopolysaccharide-mediated signaling pathway +
                                                is-aregulation of netrin-activated signaling pathway +
                                                is-aregulation of neuronal signal transduction +
                                                is-aregulation of neurotrophin TRK receptor signaling pathway +
                                                is-aregulation of Notch signaling pathway +
                                                is-aregulation of peptidoglycan recognition protein signaling pathway +
                                                is-aregulation of peroxisome proliferator activated receptor signaling pathway +
                                                is-aregulation of platelet-derived growth factor receptor signaling pathway +
                                                is-aregulation of receptor activity +
                                                is-aregulation of red or far-red light signaling pathway +
                                                is-aregulation of retinoic acid receptor signaling pathway +
                                                is-aregulation of Roundabout signaling pathway +
                                                is-aregulation of salicylic acid mediated signaling pathway +
                                                is-aregulation of semaphorin-plexin signaling pathway +
                                                is-aregulation of sevenless signaling pathway +
                                                is-aregulation of signal transduction by receptor internalization +
                                                is-aregulation of signal transduction in response to host +
                                                is-aregulation of signal transduction involved in conjugation with cellular fusion +
                                                is-aregulation of smoothened signaling pathway +
                                                is-aregulation of sphingolipid mediated signaling pathway +
                                                is-aregulation of SREBP signaling pathway +
                                                is-aregulation of thyroid hormone mediated signaling pathway +
                                                is-aregulation of Toll signaling pathway +
                                                is-aregulation of toll-like receptor signaling pathway +
                                                is-aregulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                is-aregulation of vascular endothelial growth factor receptor signaling pathway +
                                                is-aregulation of vascular endothelial growth factor signaling pathway +
                                                is-aregulation of vitamin D receptor signaling pathway +
                                                is-aregulation of Wnt signaling pathway +
                                                is-asignal clustering
                                                is-asignal complex assembly


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        negatively-regulatesnegative regulation of cellular process
                                is-anegative regulation of cell communication
                                        is-anegative regulation of atrial cardiac muscle cell action potential +
                                        is-anegative regulation of AV node cell action potential +
                                        is-anegative regulation of BMP secretion +
                                        is-anegative regulation of cell communication by chemical coupling
                                        is-anegative regulation of cell communication by electrical coupling +
                                        is-anegative regulation of cellular response to amino acid starvation
                                        is-anegative regulation of cellular response to iron ion starvation
                                        is-anegative regulation of cellular response to nitrogen starvation
                                        is-anegative regulation of establishment of competence for transformation
                                        is-anegative regulation of hormone secretion +
                                        is-anegative regulation of signal transduction [GO:0009968] (995 genes, 1756 annotations)
                                                is-aextracellular negative regulation of signal transduction +
                                                is-ametarhodopsin inactivation
                                                is-anegative adaptation of signaling pathway +
                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                is-anegative regulation of acetylcholine-gated cation channel activity
                                                is-anegative regulation of advanced glycation end-product receptor activity
                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                is-anegative regulation of apolipoprotein A-I-mediated signaling pathway
                                                is-anegative regulation of apoptotic signaling pathway +
                                                is-anegative regulation of auxin mediated signaling pathway
                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                is-anegative regulation of CD40 signaling pathway
                                                is-anegative regulation of corticotropin-releasing hormone receptor activity
                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                is-anegative regulation of endoplasmic reticulum unfolded protein response +
                                                is-anegative regulation of ephrin receptor signaling pathway
                                                is-anegative regulation of ERBB signaling pathway +
                                                is-anegative regulation of excitatory postsynaptic potential
                                                is-anegative regulation of Fas signaling pathway
                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                is-anegative regulation of glucose mediated signaling pathway
                                                is-anegative regulation of glutamate receptor signaling pathway +
                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                is-anegative regulation of insulin receptor signaling pathway +
                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                is-anegative regulation of integrin-mediated signaling pathway
                                                is-anegative regulation of intracellular signal transduction +
                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                is-anegative regulation of nerve growth factor receptor activity
                                                is-anegative regulation of netrin-activated signaling pathway
                                                is-anegative regulation of neuronal signal transduction
                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                is-anegative regulation of Notch signaling pathway +
                                                is-anegative regulation of osmolarity-sensing cation channel activity
                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                is-anegative regulation of red or far-red light signaling pathway
                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                is-anegative regulation of Roundabout signaling pathway +
                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                is-anegative regulation of sevenless signaling pathway
                                                is-anegative regulation of signal transduction by receptor internalization +
                                                is-anegative regulation of signal transduction in absence of ligand +
                                                is-anegative regulation of signal transduction in response to host +
                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                is-anegative regulation of smoothened signaling pathway +
                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                is-anegative regulation of SREBP signaling pathway +
                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                is-anegative regulation of thyroid hormone receptor activity
                                                is-anegative regulation of Toll signaling pathway
                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                is-anegative regulation of Wnt signaling pathway +
                                                is-atermination of signal transduction +
                                        is-anegative regulation of sorocarp spore cell differentiation
                                        is-anegative regulation of sorocarp stalk cell differentiation
                                        is-anegative regulation of synaptic transmission +
                                        is-anegative regulation of transmission of nerve impulse +
                                        is-anegative regulation of trichome patterning
                                        is-anegative regulation of Wnt protein secretion


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-anegative regulation of cellular process
                                        is-anegative regulation of cell communication
                                                is-anegative regulation of atrial cardiac muscle cell action potential +
                                                is-anegative regulation of AV node cell action potential +
                                                is-anegative regulation of BMP secretion +
                                                is-anegative regulation of cell communication by chemical coupling
                                                is-anegative regulation of cell communication by electrical coupling +
                                                is-anegative regulation of cellular response to amino acid starvation
                                                is-anegative regulation of cellular response to iron ion starvation
                                                is-anegative regulation of cellular response to nitrogen starvation
                                                is-anegative regulation of establishment of competence for transformation
                                                is-anegative regulation of hormone secretion +
                                                is-anegative regulation of signal transduction [GO:0009968] (995 genes, 1756 annotations)
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of acetylcholine-gated cation channel activity
                                                        is-anegative regulation of advanced glycation end-product receptor activity
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apolipoprotein A-I-mediated signaling pathway
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of corticotropin-releasing hormone receptor activity
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response +
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of excitatory postsynaptic potential
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway +
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of osmolarity-sensing cation channel activity
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of thyroid hormone receptor activity
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +
                                                is-anegative regulation of sorocarp spore cell differentiation
                                                is-anegative regulation of sorocarp stalk cell differentiation
                                                is-anegative regulation of synaptic transmission +
                                                is-anegative regulation of transmission of nerve impulse +
                                                is-anegative regulation of trichome patterning
                                                is-anegative regulation of Wnt protein secretion


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-aregulation of cell communication
                                        is-anegative regulation of cell communication
                                                is-anegative regulation of atrial cardiac muscle cell action potential +
                                                is-anegative regulation of AV node cell action potential +
                                                is-anegative regulation of BMP secretion +
                                                is-anegative regulation of cell communication by chemical coupling
                                                is-anegative regulation of cell communication by electrical coupling +
                                                is-anegative regulation of cellular response to amino acid starvation
                                                is-anegative regulation of cellular response to iron ion starvation
                                                is-anegative regulation of cellular response to nitrogen starvation
                                                is-anegative regulation of establishment of competence for transformation
                                                is-anegative regulation of hormone secretion +
                                                is-anegative regulation of signal transduction [GO:0009968] (995 genes, 1756 annotations)
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of acetylcholine-gated cation channel activity
                                                        is-anegative regulation of advanced glycation end-product receptor activity
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apolipoprotein A-I-mediated signaling pathway
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of corticotropin-releasing hormone receptor activity
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response +
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of excitatory postsynaptic potential
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway +
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of osmolarity-sensing cation channel activity
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of thyroid hormone receptor activity
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +
                                                is-anegative regulation of sorocarp spore cell differentiation
                                                is-anegative regulation of sorocarp stalk cell differentiation
                                                is-anegative regulation of synaptic transmission +
                                                is-anegative regulation of transmission of nerve impulse +
                                                is-anegative regulation of trichome patterning
                                                is-anegative regulation of Wnt protein secretion


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-aregulation of cell communication
                                        is-aregulation of signal transduction
                                                is-aadaptation of signaling pathway +
                                                is-aextracellular regulation of signal transduction +
                                                is-amodulation of excitatory postsynaptic potential +
                                                is-amodulation of inhibitory postsynaptic potential +
                                                is-amodulation of signal transduction in other organism +
                                                is-anegative regulation of signal transduction [GO:0009968] (995 genes, 1756 annotations)
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of acetylcholine-gated cation channel activity
                                                        is-anegative regulation of advanced glycation end-product receptor activity
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apolipoprotein A-I-mediated signaling pathway
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegativ