Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Bmi1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes BMI1,COMMD3-BMI1
- Mouse genes Bmi1
- Rat genes Bmi1
- Zfish genes bmi1a,bmi1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bmi1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Bmi1	IDA		Mouse	PMID:24105743
Molecular Function	GO:0003682	chromatin binding	Bmi1	IDA		Mouse	PMID:16359901
Molecular Function	GO:1990841	promoter-specific chromatin binding	BMI1	IDA		Human	PMID:24623306
Molecular Function	GO:1990841	promoter-specific chromatin binding	Bmi1	IDA		Mouse	PMID:22770845
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q06587	Human	PMID:15386022
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q99496	Human	PMID:15386022
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q99496	Human	PMID:16710298
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:O00257	Human	PMID:17332741
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:O95931	Human	PMID:17332741
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q9HC52	Human	PMID:17332741
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:P0CG48	Human	PMID:19233177
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:O00257	Human	PMID:19636380
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:O95931	Human	PMID:19636380
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:P78364	Human	PMID:19636380
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q06587	Human	PMID:19636380
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q8IXK0	Human	PMID:19636380
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q99496	Human	PMID:19636380
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q9HC52	Human	PMID:19636380
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:P60484	Human	PMID:19903340
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:O95931	Human	PMID:20543829
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q99496	Human	PMID:20543829
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q9HC52	Human	PMID:20543829
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q9HCE1	Human	PMID:20543829
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:O00257	Human	PMID:20601937
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:O95503	Human	PMID:20601937
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:O95931	Human	PMID:20601937
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:P0CG48	Human	PMID:20601937
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:P51784	Human	PMID:20601937
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:P78364	Human	PMID:20601937
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q06587	Human	PMID:20601937
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q8IXK0	Human	PMID:20601937
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q93009	Human	PMID:20601937
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q99496	Human	PMID:20601937
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q9HC52	Human	PMID:20601937
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:O00257-3	Human	PMID:21282530
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:O95503	Human	PMID:21282530
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:O95931	Human	PMID:21282530
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:P68400	Human	PMID:21282530
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q9HC52	Human	PMID:21282530
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q99496	Human	PMID:21772249
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:O00257	Human	PMID:22078878
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q06587	Human	PMID:22493164
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q99496	Human	PMID:22493164
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q9H270	Human	PMID:22493164
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q06587	Human	PMID:22897849
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q99496	Human	PMID:22902369
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:P78364	Human	PMID:23523425
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:O95503	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:O95931	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q06587	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q99496	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q9HC52	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q14157	Human	PMID:25185265
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q06587	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q8IXK0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q9GZM8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:O00257	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q99496	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q9HC52	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:O00257	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:O95503	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:O95931	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:P78364	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q06587	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q8IXK0	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q99496	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q9HC52	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:O95931	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:P78364	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q06587	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q99496	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q9P202	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:O00257	Human	PMID:34316702
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:O94906	Human	PMID:34316702
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:O95503	Human	PMID:34316702
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:P68400	Human	PMID:34316702
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q06587	Human	PMID:34316702
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q8IXK0	Human	PMID:34316702
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q99496	Human	PMID:34316702
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q9HC52	Human	PMID:34316702
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q9HCE1	Human	PMID:34316702
Molecular Function	GO:0005515	protein binding	BMI1	IPI	UniProtKB:Q93009	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Bmi1	IPI	UniProtKB:Q9CQJ4	Mouse	MGI:MGI:3807116\|PMID:18650381
Molecular Function	GO:0005515	protein binding	Bmi1	IPI	UniProtKB:Q8IXK0	Mouse	MGI:MGI:3846485\|PMID:19369945
Molecular Function	GO:0005515	protein binding	Bmi1	IPI	UniProtKB:O88509\|UniProtKB:Q60848	Mouse	MGI:MGI:6092708\|PMID:17726103
Molecular Function	GO:0005515	protein binding	Bmi1	IPI	UniProtKB:Q8IXK0	Mouse	MGI:MGI:2384443\|PMID:12167701
Molecular Function	GO:0005515	protein binding	Bmi1	IPI	UniProtKB:Q9CQJ4	Mouse	MGI:MGI:3715707\|PMID:17296600
Molecular Function	GO:0005515	protein binding	Bmi1	IPI	PR:Q9CQJ4	Mouse	PMID:17107999
Molecular Function	GO:0005515	protein binding	Bmi1	IPI	MGI:MGI:1890393	Mouse	PMID:20808772
Molecular Function	GO:0005515	protein binding	Bmi1	IPI	PR:O55187	Mouse	PMID:9367786
Molecular Function	GO:0005515	protein binding	Bmi1	IPI	PR:P30658	Mouse	PMID:9367786
Molecular Function	GO:0005515	protein binding	Bmi1	IPI	PR:Q00899	Mouse	PMID:17107999
Molecular Function	GO:0005515	protein binding	Bmi1	IPI	PR:Q9QWH1	Mouse	PMID:16359901
Molecular Function	GO:0005515	protein binding	Bmi1	IPI	PR:Q9QWH1	Mouse	PMID:9627119
Molecular Function	GO:0005515	protein binding	Bmi1	IPI	PR:O35730	Mouse	PMID:16359901
Molecular Function	GO:0005515	protein binding	Bmi1	IPI	PR:Q9CQJ4	Mouse	PMID:20808772
Molecular Function	GO:0005515	protein binding	Bmi1	IPI	PR:Q9CQJ4	Mouse	PMID:16359901
Molecular Function	GO:0005515	protein binding	Bmi1	IPI	PR:Q9CQJ4	Mouse	PMID:12183370
Molecular Function	GO:0005515	protein binding	Bmi1	IPI	PR:Q9QXV1	Mouse	PMID:16359901
Molecular Function	GO:0071535	RING-like zinc finger domain binding	BMI1	IPI	UniProtKB:Q99496	Human	PMID:16714294
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Bmi1	IDA		Mouse	PMID:17107999
Molecular Function	GO:0043565	sequence-specific DNA binding	Bmi1	IDA		Mouse	PMID:20956546
Molecular Function	GO:0097027	ubiquitin-protein transferase activator activity	Bmi1	IDA		Mouse	PMID:16359901
Molecular Function	GO:0008270	zinc ion binding	BMI1	IDA		Human	PMID:16714294
Cellular Component	GO:0005829	cytosol	BMI1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000792	heterochromatin	Bmi1	IDA		Mouse	PMID:18311137
Cellular Component	GO:0016604	nuclear body	BMI1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	Bmi1	IDA		Mouse	PMID:12183370
Cellular Component	GO:0005634	nucleus	BMI1	IDA		Human	PMID:10445843
Cellular Component	GO:0005634	nucleus	BMI1	IDA		Human	PMID:21282530
Cellular Component	GO:0005634	nucleus	BMI1	IDA		Human	PMID:9367786
Cellular Component	GO:0031519	PcG protein complex	BMI1	IDA		Human	PMID:21282530
Cellular Component	GO:0031519	PcG protein complex	BMI1	IDA		Human	PMID:26151332
Cellular Component	GO:0031519	PcG protein complex	Bmi1	IDA		Mouse	PMID:16624538
Cellular Component	GO:0035102	PRC1 complex	BMI1	IDA		Human	PMID:12167701
Cellular Component	GO:0035102	PRC1 complex	BMI1	IDA		Human	PMID:19636380
Cellular Component	GO:0035102	PRC1 complex	Bmi1	IDA		Mouse	PMID:16359901
Cellular Component	GO:0000151	ubiquitin ligase complex	BMI1	IDA		Human	PMID:16714294
Biological Process	GO:0097190	apoptotic signaling pathway	Bmi1	IGI	MGI:MGI:99161	Mouse	PMID:11290297
Biological Process	GO:0007420	brain development	Bmi1	IMP	MGI:MGI:1857632	Mouse	PMID:7926765
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	Bmi1	IEP		Rat	PMID:21368868\|RGD:5507827
Biological Process	GO:0071347	cellular response to interleukin-1	Bmi1	IEP		Rat	PMID:22706317\|RGD:7240518
Biological Process	GO:0021549	cerebellum development	bmi1a	IGI	ZFIN:ZDB-MRPHLNO-121120-7,ZFIN:ZDB-MRPHLNO-121127-1	Zfish	PMID:23023333
Biological Process	GO:0021549	cerebellum development	bmi1b	IGI	ZFIN:ZDB-MRPHLNO-121120-7,ZFIN:ZDB-MRPHLNO-121127-1	Zfish	PMID:23023333
Biological Process	GO:0006325	chromatin organization	Bmi1	IGI	MGI:MGI:99161	Mouse	PMID:16687444
Biological Process	GO:0006325	chromatin organization	Bmi1	IDA		Mouse	PMID:16359901
Biological Process	GO:0006306	DNA methylation	Bmi1	IMP		Mouse	PMID:24105743
Biological Process	GO:0048706	embryonic skeletal system development	Bmi1	IGI	MGI:MGI:99161	Mouse	PMID:11290297
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Bmi1	IGI	MGI:MGI:99161	Mouse	PMID:11290297
Biological Process	GO:0035701	hematopoietic stem cell migration	bmi1a	IMP	ZFIN:ZDB-GENO-131120-54	Zfish	PMID:21828130
Biological Process	GO:0030097	hemopoiesis	BMI1	IEP		Human	PMID:15334543
Biological Process	GO:0036353	histone H2A-K119 monoubiquitination	BMI1	IMP		Human	PMID:26151332
Biological Process	GO:0006959	humoral immune response	Bmi1	IMP	MGI:MGI:1857632	Mouse	PMID:7926765
Biological Process	GO:0001701	in utero embryonic development	Bmi1	IGI	MGI:MGI:99161	Mouse	PMID:11290297
Biological Process	GO:2001234	negative regulation of apoptotic signaling pathway	Bmi1	IGI	MGI:MGI:99161	Mouse	PMID:11290297
Biological Process	GO:0045814	negative regulation of gene expression, epigenetic	BMI1	IMP		Human	PMID:24623306
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	BMI1	IMP		Human	PMID:19636380
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Bmi1	IGI	MGI:MGI:95286	Mouse	PMID:17107999
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Bmi1	IDA		Mouse	PMID:9367786
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Bmi1	IDA		Mouse	PMID:9312051
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Bmi1	IGI	MGI:MGI:99161	Mouse	PMID:11290297
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Bmi1	IMP		Mouse	PMID:24105743
Biological Process	GO:0030890	positive regulation of B cell proliferation	Bmi1	IMP		Mouse	MGI:MGI:3615850\|PMID:15964995
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	BMI1	IMP		Human	PMID:17420273
Biological Process	GO:0033092	positive regulation of immature T cell proliferation in thymus	Bmi1	IMP		Mouse	MGI:MGI:3615850\|PMID:15964995
Biological Process	GO:0051443	positive regulation of ubiquitin-protein transferase activity	BMI1	IDA		Human	PMID:16714294
Biological Process	GO:0060215	primitive hemopoiesis	bmi1a	IMP	ZFIN:ZDB-GENO-131120-54	Zfish	PMID:21828130
Biological Process	GO:2000011	regulation of adaxial/abaxial pattern formation	Bmi1	IGI	MGI:MGI:95286	Mouse	PMID:17107999
Biological Process	GO:0010468	regulation of gene expression	BMI1	IMP		Human	PMID:17420273
Biological Process	GO:0090183	regulation of kidney development	Bmi1	IEP		Rat	PMID:18467665\|RGD:155631277
Biological Process	GO:0021903	rostrocaudal neural tube patterning	Bmi1	IMP	MGI:MGI:1857632	Mouse	PMID:8887324
Biological Process	GO:0001501	skeletal system development	Bmi1	IMP	MGI:MGI:1857632	Mouse	PMID:7926765
Biological Process	GO:0048103	somatic stem cell division	Bmi1	IMP	MGI:MGI:1857632	Mouse	PMID:12714971

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/21/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.