Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARHGAP44
  • Mouse genes Arhgap44
  • Rat genes Arhgap44
  • Zfish genes arhgap44a,arhgap44b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arhgap44

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	Arhgap44	IDA		Mouse	MGI:MGI:5582709|PMID:24352656
Molecular Function	GO:0005096	GTPase activator activity	Arhgap44	IDA		Rat	PMID:25498153|RGD:14402441
Molecular Function	GO:0005543	phospholipid binding	ARHGAP44	IDA		Human	PMID:22750946
Molecular Function	GO:0005515	protein binding	ARHGAP44	IPI	UniProtKB:Q811A2	Human	PMID:19273615
Molecular Function	GO:0031267	small GTPase binding	Arhgap44	IPI	UniProtKB:P63001	Mouse	MGI:MGI:5582709|PMID:24352656
Cellular Component	GO:0030425	dendrite	Arhgap44	IDA		Rat	PMID:25498153|RGD:14402441
Cellular Component	GO:0043197	dendritic spine	Arhgap44	IDA		Mouse	MGI:MGI:5582709|PMID:24352656
Cellular Component	GO:0098978	glutamatergic synapse	Arhgap44	IDA		Mouse	PMID:23739967
Cellular Component	GO:0098978	glutamatergic synapse	Arhgap44	IMP		Mouse	PMID:23739967
Cellular Component	GO:0098978	glutamatergic synapse	Arhgap44	IDA		Rat	PMID:23739967|RGD:12050108
Cellular Component	GO:0031256	leading edge membrane	ARHGAP44	IDA		Human	PMID:22750946
Cellular Component	GO:0014069	postsynaptic density	Arhgap44	IDA		Rat	PMID:23739967|RGD:12050108
Cellular Component	GO:0048786	presynaptic active zone	Arhgap44	IDA		Rat	PMID:23739967|RGD:12050108
Biological Process	GO:0098886	modification of dendritic spine	Arhgap44	IMP		Mouse	MGI:MGI:5498598|PMID:23739967
Biological Process	GO:0099010	modification of postsynaptic structure	Arhgap44	IDA		Mouse	PMID:23739967
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Arhgap44	IMP		Mouse	PMID:23739967
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Arhgap44	IDA		Mouse	PMID:23739967
Biological Process	GO:0051490	negative regulation of filopodium assembly	Arhgap44	IDA		Rat	PMID:25498153|RGD:14402441
Biological Process	GO:0035021	negative regulation of Rac protein signal transduction	Arhgap44	IMP		Mouse	MGI:MGI:5582709|PMID:24352656
Biological Process	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane	Arhgap44	IMP		Mouse	MGI:MGI:5498598|PMID:23739967
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	Arhgap44	IMP		Mouse	MGI:MGI:5819328|PMID:26969129
Biological Process	GO:0061001	regulation of dendritic spine morphogenesis	Arhgap44	IMP		Mouse	MGI:MGI:5582709|PMID:24352656
Biological Process	GO:0043087	regulation of GTPase activity	Arhgap44	IDA		Mouse	MGI:MGI:5582709|PMID:24352656
Biological Process	GO:0043087	regulation of GTPase activity	Arhgap44	IDA		Rat	PMID:25498153|RGD:14402441
Biological Process	GO:0099152	regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane	Arhgap44	IDA		Mouse	PMID:23739967
Biological Process	GO:0099152	regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane	Arhgap44	IMP		Mouse	PMID:23739967

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern