Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARFGEF2
  • Mouse genes Arfgef2
  • Rat genes Arfgef2
  • Zfish genes arfgef2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arfgef2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050811	GABA receptor binding	Arfgef2	IMP		Rat	PMID:15198677|RGD:1304338
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ARFGEF2	IDA		Human	PMID:10212200
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ARFGEF2	IDA		Human	PMID:15385626
Molecular Function	GO:0017022	myosin binding	Arfgef2	IPI	UniProtKB:Q63358	Rat	PMID:15644318|RGD:1579801
Molecular Function	GO:0005515	protein binding	ARFGEF2	IPI	UniProtKB:Q9Y6D6	Human	PMID:10716990
Molecular Function	GO:0005515	protein binding	ARFGEF2	IPI	UniProtKB:Q9UPT5-1	Human	PMID:15705715
Molecular Function	GO:0005515	protein binding	ARFGEF2	IPI	UniProtKB:Q99417	Human	PMID:16866877
Molecular Function	GO:0005515	protein binding	ARFGEF2	IPI	UniProtKB:Q14432	Human	PMID:19332778
Molecular Function	GO:0005515	protein binding	ARFGEF2	IPI	UniProtKB:Q9Y6D6	Human	PMID:19332778
Molecular Function	GO:0005515	protein binding	ARFGEF2	IPI	UniProtKB:Q9Y6D6	Human	PMID:22084092
Molecular Function	GO:0005515	protein binding	Arfgef2	IPI	UniProtKB:P63079	Rat	PMID:15198677|RGD:1304338
Molecular Function	GO:0034237	protein kinase A regulatory subunit binding	ARFGEF2	IDA		Human	PMID:12571360
Cellular Component	GO:0032279	asymmetric synapse	Arfgef2	IDA		Rat	PMID:15198677|RGD:1304338
Cellular Component	GO:0005879	axonemal microtubule	Arfgef2	IDA		Rat	PMID:15198677|RGD:1304338
Cellular Component	GO:0005737	cytoplasm	Arfgef2	IDA		Rat	PMID:12051703|RGD:634614
Cellular Component	GO:0031410	cytoplasmic vesicle	Arfgef2	IDA		Rat	PMID:15198677|RGD:1304338
Cellular Component	GO:0005829	cytosol	ARFGEF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	ARFGEF2	IDA		Human	PMID:12571360
Cellular Component	GO:0043197	dendritic spine	Arfgef2	IDA		Rat	PMID:15198677|RGD:1304338
Cellular Component	GO:0098982	GABA-ergic synapse	Arfgef2	IDA		Rat	PMID:15198677|RGD:1304338
Cellular Component	GO:0098978	glutamatergic synapse	Arfgef2	IDA		Rat	PMID:15198677|RGD:1304338
Cellular Component	GO:0005794	Golgi apparatus	ARFGEF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000139	Golgi membrane	ARFGEF2	IDA		Human	PMID:10716990
Cellular Component	GO:0000139	Golgi membrane	ARFGEF2	IDA		Human	PMID:12571360
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ARFGEF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	ARFGEF2	IDA		Human	PMID:12571360
Cellular Component	GO:0016020	membrane	ARFGEF2	HDA		Human	PMID:19946888
Cellular Component	GO:0005815	microtubule organizing center	ARFGEF2	IDA		Human	PMID:15705715
Cellular Component	GO:0098794	postsynapse	Arfgef2	IDA		Rat	PMID:15198677|RGD:1304338
Cellular Component	GO:0098793	presynapse	Arfgef2	IDA		Rat	PMID:15198677|RGD:1304338
Cellular Component	GO:0055037	recycling endosome	ARFGEF2	IDA		Human	PMID:15385626
Cellular Component	GO:0032280	symmetric synapse	Arfgef2	IDA		Rat	PMID:15198677|RGD:1304338
Cellular Component	GO:0005802	trans-Golgi network	Arfgef2	IDA		Rat	PMID:11809827|RGD:2316366
Cellular Component	GO:0005802	trans-Golgi network	Arfgef2	IDA		Rat	PMID:15198677|RGD:1304338
Biological Process	GO:0035476	angioblast cell migration	arfgef2	IMP	ZFIN:ZDB-MRPHLNO-200221-1	Zfish	PMID:31199673
Biological Process	GO:0002042	cell migration involved in sprouting angiogenesis	arfgef2	IMP	ZFIN:ZDB-MRPHLNO-200221-1	Zfish	PMID:31199673
Biological Process	GO:0010256	endomembrane system organization	ARFGEF2	IMP		Human	PMID:20360857
Biological Process	GO:0007032	endosome organization	ARFGEF2	IMP		Human	PMID:20360857
Biological Process	GO:0006887	exocytosis	Arfgef2	IMP		Rat	PMID:15198677|RGD:1304338
Biological Process	GO:0006893	Golgi to plasma membrane transport	ARFGEF2	IMP		Human	PMID:17276987
Biological Process	GO:0035556	intracellular signal transduction	ARFGEF2	IDA		Human	PMID:12571360
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	ARFGEF2	IMP		Human	PMID:17276987
Biological Process	GO:0001881	receptor recycling	ARFGEF2	IDA		Human	PMID:16477018

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern