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Gene Ontology Browser
Term Detail
GO term:trans-Golgi network
Synonym: Golgi trans face
Synonym: Golgi trans-face
Synonym: late Golgi
Synonym: maturing face
Synonym: TGN
Synonym: trans Golgi network
GO id:GO:0005802
Definition:The network of interconnected tubular and cisternal structures located at the side of the Golgi apparatus distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
CommentsThe TGN is not considered part of the Golgi apparatus but is a separate organelle.
Number of paths to term: 6

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-aintracellular organelle
                                                        is-aintracellular membrane-bounded organelle
                                                                is-aacidocalcisome +
                                                                is-aanammoxosome
                                                                is-aattachment organelle +
                                                                is-acis-Golgi network +
                                                                is-acytoplasmic membrane-bounded vesicle +
                                                                is-aendoplasmic reticulum +
                                                                is-aendoplasmic reticulum-Golgi intermediate compartment +
                                                                is-aendosome +
                                                                is-aER body
                                                                is-aexoneme
                                                                is-aGolgi apparatus +
                                                                is-ahydrogenosome +
                                                                is-akaryomere
                                                                is-amethane-oxidizing organelle
                                                                is-amicrobody +
                                                                is-amicroneme +
                                                                is-amitochondrion +
                                                                is-amitosome
                                                                is-amononeme
                                                                is-anucleomorph
                                                                is-anucleus +
                                                                is-aPHA granule
                                                                is-apirellulosome
                                                                is-aplastid +
                                                                is-aplatelet dense tubular network +
                                                                is-aprotein body
                                                                is-asubsynaptic reticulum
                                                                is-atrans-Golgi network [GO:0005802] (133 genes, 151 annotations)
                                                                        part-oftrans-Golgi network membrane
                                                                is-avacuole +
                                                                is-aviral assembly compartment
                                                                is-avirion transport vesicle


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-aintracellular organelle
                                                is-aintracellular membrane-bounded organelle
                                                        is-aacidocalcisome +
                                                        is-aanammoxosome
                                                        is-aattachment organelle +
                                                        is-acis-Golgi network +
                                                        is-acytoplasmic membrane-bounded vesicle +
                                                        is-aendoplasmic reticulum +
                                                        is-aendoplasmic reticulum-Golgi intermediate compartment +
                                                        is-aendosome +
                                                        is-aER body
                                                        is-aexoneme
                                                        is-aGolgi apparatus +
                                                        is-ahydrogenosome +
                                                        is-akaryomere
                                                        is-amethane-oxidizing organelle
                                                        is-amicrobody +
                                                        is-amicroneme +
                                                        is-amitochondrion +
                                                        is-amitosome
                                                        is-amononeme
                                                        is-anucleomorph
                                                        is-anucleus +
                                                        is-aPHA granule
                                                        is-apirellulosome
                                                        is-aplastid +
                                                        is-aplatelet dense tubular network +
                                                        is-aprotein body
                                                        is-asubsynaptic reticulum
                                                        is-atrans-Golgi network [GO:0005802] (133 genes, 151 annotations)
                                                                part-oftrans-Golgi network membrane
                                                        is-avacuole +
                                                        is-aviral assembly compartment
                                                        is-avirion transport vesicle


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-aintracellular organelle
                                                is-aintracellular membrane-bounded organelle
                                                        is-aacidocalcisome +
                                                        is-aanammoxosome
                                                        is-aattachment organelle +
                                                        is-acis-Golgi network +
                                                        is-acytoplasmic membrane-bounded vesicle +
                                                        is-aendoplasmic reticulum +
                                                        is-aendoplasmic reticulum-Golgi intermediate compartment +
                                                        is-aendosome +
                                                        is-aER body
                                                        is-aexoneme
                                                        is-aGolgi apparatus +
                                                        is-ahydrogenosome +
                                                        is-akaryomere
                                                        is-amethane-oxidizing organelle
                                                        is-amicrobody +
                                                        is-amicroneme +
                                                        is-amitochondrion +
                                                        is-amitosome
                                                        is-amononeme
                                                        is-anucleomorph
                                                        is-anucleus +
                                                        is-aPHA granule
                                                        is-apirellulosome
                                                        is-aplastid +
                                                        is-aplatelet dense tubular network +
                                                        is-aprotein body
                                                        is-asubsynaptic reticulum
                                                        is-atrans-Golgi network [GO:0005802] (133 genes, 151 annotations)
                                                                part-oftrans-Golgi network membrane
                                                        is-avacuole +
                                                        is-aviral assembly compartment
                                                        is-avirion transport vesicle


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-aintracellular organelle
                                        is-aintracellular membrane-bounded organelle
                                                is-aacidocalcisome +
                                                is-aanammoxosome
                                                is-aattachment organelle +
                                                is-acis-Golgi network +
                                                is-acytoplasmic membrane-bounded vesicle +
                                                is-aendoplasmic reticulum +
                                                is-aendoplasmic reticulum-Golgi intermediate compartment +
                                                is-aendosome +
                                                is-aER body
                                                is-aexoneme
                                                is-aGolgi apparatus +
                                                is-ahydrogenosome +
                                                is-akaryomere
                                                is-amethane-oxidizing organelle
                                                is-amicrobody +
                                                is-amicroneme +
                                                is-amitochondrion +
                                                is-amitosome
                                                is-amononeme
                                                is-anucleomorph
                                                is-anucleus +
                                                is-aPHA granule
                                                is-apirellulosome
                                                is-aplastid +
                                                is-aplatelet dense tubular network +
                                                is-aprotein body
                                                is-asubsynaptic reticulum
                                                is-atrans-Golgi network [GO:0005802] (133 genes, 151 annotations)
                                                        part-oftrans-Golgi network membrane
                                                is-avacuole +
                                                is-aviral assembly compartment
                                                is-avirion transport vesicle


Gene_Ontology
        is-acellular_component
                is-aorganelle
                        is-aintracellular organelle
                                is-aintracellular membrane-bounded organelle
                                        is-aacidocalcisome +
                                        is-aanammoxosome
                                        is-aattachment organelle +
                                        is-acis-Golgi network +
                                        is-acytoplasmic membrane-bounded vesicle +
                                        is-aendoplasmic reticulum +
                                        is-aendoplasmic reticulum-Golgi intermediate compartment +
                                        is-aendosome +
                                        is-aER body
                                        is-aexoneme
                                        is-aGolgi apparatus +
                                        is-ahydrogenosome +
                                        is-akaryomere
                                        is-amethane-oxidizing organelle
                                        is-amicrobody +
                                        is-amicroneme +
                                        is-amitochondrion +
                                        is-amitosome
                                        is-amononeme
                                        is-anucleomorph
                                        is-anucleus +
                                        is-aPHA granule
                                        is-apirellulosome
                                        is-aplastid +
                                        is-aplatelet dense tubular network +
                                        is-aprotein body
                                        is-asubsynaptic reticulum
                                        is-atrans-Golgi network [GO:0005802] (133 genes, 151 annotations)
                                                part-oftrans-Golgi network membrane
                                        is-avacuole +
                                        is-aviral assembly compartment
                                        is-avirion transport vesicle


Gene_Ontology
        is-acellular_component
                is-aorganelle
                        is-amembrane-bounded organelle
                                is-aintracellular membrane-bounded organelle
                                        is-aacidocalcisome +
                                        is-aanammoxosome
                                        is-aattachment organelle +
                                        is-acis-Golgi network +
                                        is-acytoplasmic membrane-bounded vesicle +
                                        is-aendoplasmic reticulum +
                                        is-aendoplasmic reticulum-Golgi intermediate compartment +
                                        is-aendosome +
                                        is-aER body
                                        is-aexoneme
                                        is-aGolgi apparatus +
                                        is-ahydrogenosome +
                                        is-akaryomere
                                        is-amethane-oxidizing organelle
                                        is-amicrobody +
                                        is-amicroneme +
                                        is-amitochondrion +
                                        is-amitosome
                                        is-amononeme
                                        is-anucleomorph
                                        is-anucleus +
                                        is-aPHA granule
                                        is-apirellulosome
                                        is-aplastid +
                                        is-aplatelet dense tubular network +
                                        is-aprotein body
                                        is-asubsynaptic reticulum
                                        is-atrans-Golgi network [GO:0005802] (133 genes, 151 annotations)
                                                part-oftrans-Golgi network membrane
                                        is-avacuole +
                                        is-aviral assembly compartment
                                        is-avirion transport vesicle


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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory