| GO term: | trans-Golgi network |
| Synonym: | Golgi trans face |
| Synonym: | Golgi trans-face |
| Synonym: | late Golgi |
| Synonym: | maturing face |
| Synonym: | TGN |
| Synonym: | trans Golgi network |
| GO id: | GO:0005802 |
| Definition: | The network of interconnected tubular and cisternal structures located at the side of the Golgi apparatus distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination. |
| Comments | The TGN is not considered part of the Golgi apparatus but is a separate organelle. |
| Number of paths to term: | 6 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
cellular_componentcellcell partintracellularintracellular partintracellular organelleintracellular membrane-bounded organelleacidocalcisome +anammoxosomeattachment organelle +axoneme +cilium +cis-Golgi network +cytoplasmic membrane-bounded vesicle +endoplasmic reticulum +endoplasmic reticulum-Golgi intermediate compartment +endosome +ER bodyexonemeGolgi apparatus +hydrogenosome +karyomeremethane-oxidizing organellemicrobody +microneme +mitochondrion +mitosomemonolayer-surrounded lipid storage body +mononemenucleomorphnucleus +PHA granulepirellulosomeplastid +platelet dense tubular network +protein bodysubsynaptic reticulumtrans-Golgi network [GO:0005802] (121 genes, 138 annotations)trans-Golgi network membranevacuole +viral assembly compartmentvirion transport vesiclecellular_componentcellcell partintracellular partintracellular organelleintracellular membrane-bounded organelleacidocalcisome +anammoxosomeattachment organelle +axoneme +cilium +cis-Golgi network +cytoplasmic membrane-bounded vesicle +endoplasmic reticulum +endoplasmic reticulum-Golgi intermediate compartment +endosome +ER bodyexonemeGolgi apparatus +hydrogenosome +karyomeremethane-oxidizing organellemicrobody +microneme +mitochondrion +mitosomemonolayer-surrounded lipid storage body +mononemenucleomorphnucleus +PHA granulepirellulosomeplastid +platelet dense tubular network +protein bodysubsynaptic reticulumtrans-Golgi network [GO:0005802] (121 genes, 138 annotations)trans-Golgi network membranevacuole +viral assembly compartmentvirion transport vesiclecellular_componentcell partintracellularintracellular partintracellular organelleintracellular membrane-bounded organelleacidocalcisome +anammoxosomeattachment organelle +axoneme +cilium +cis-Golgi network +cytoplasmic membrane-bounded vesicle +endoplasmic reticulum +endoplasmic reticulum-Golgi intermediate compartment +endosome +ER bodyexonemeGolgi apparatus +hydrogenosome +karyomeremethane-oxidizing organellemicrobody +microneme +mitochondrion +mitosomemonolayer-surrounded lipid storage body +mononemenucleomorphnucleus +PHA granulepirellulosomeplastid +platelet dense tubular network +protein bodysubsynaptic reticulumtrans-Golgi network [GO:0005802] (121 genes, 138 annotations)trans-Golgi network membranevacuole +viral assembly compartmentvirion transport vesiclecellular_componentcell partintracellular partintracellular organelleintracellular membrane-bounded organelleacidocalcisome +anammoxosomeattachment organelle +axoneme +cilium +cis-Golgi network +cytoplasmic membrane-bounded vesicle +endoplasmic reticulum +endoplasmic reticulum-Golgi intermediate compartment +endosome +ER bodyexonemeGolgi apparatus +hydrogenosome +karyomeremethane-oxidizing organellemicrobody +microneme +mitochondrion +mitosomemonolayer-surrounded lipid storage body +mononemenucleomorphnucleus +PHA granulepirellulosomeplastid +platelet dense tubular network +protein bodysubsynaptic reticulumtrans-Golgi network [GO:0005802] (121 genes, 138 annotations)trans-Golgi network membranevacuole +viral assembly compartmentvirion transport vesiclecellular_componentorganelleintracellular organelleintracellular membrane-bounded organelleacidocalcisome +anammoxosomeattachment organelle +axoneme +cilium +cis-Golgi network +cytoplasmic membrane-bounded vesicle +endoplasmic reticulum +endoplasmic reticulum-Golgi intermediate compartment +endosome +ER bodyexonemeGolgi apparatus +hydrogenosome +karyomeremethane-oxidizing organellemicrobody +microneme +mitochondrion +mitosomemonolayer-surrounded lipid storage body +mononemenucleomorphnucleus +PHA granulepirellulosomeplastid +platelet dense tubular network +protein bodysubsynaptic reticulumtrans-Golgi network [GO:0005802] (121 genes, 138 annotations)trans-Golgi network membranevacuole +viral assembly compartmentvirion transport vesiclecellular_componentorganellemembrane-bounded organelleintracellular membrane-bounded organelleacidocalcisome +anammoxosomeattachment organelle +axoneme +cilium +cis-Golgi network +cytoplasmic membrane-bounded vesicle +endoplasmic reticulum +endoplasmic reticulum-Golgi intermediate compartment +endosome +ER bodyexonemeGolgi apparatus +hydrogenosome +karyomeremethane-oxidizing organellemicrobody +microneme +mitochondrion +mitosomemonolayer-surrounded lipid storage body +mononemenucleomorphnucleus +PHA granulepirellulosomeplastid +platelet dense tubular network +protein bodysubsynaptic reticulumtrans-Golgi network [GO:0005802] (121 genes, 138 annotations)trans-Golgi network membranevacuole +viral assembly compartmentvirion transport vesicleMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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