Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALDOB
  • Mouse genes Aldob
  • Rat genes Aldob
  • Zfish genes aldob
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aldob

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051117	ATPase binding	ALDOB	IDA		Human	PMID:17576770
Molecular Function	GO:0008092	cytoskeletal protein binding	ALDOB	IDA		Human	PMID:9244396
Molecular Function	GO:0070061	fructose binding	ALDOB	IMP		Human	PMID:10625657
Molecular Function	GO:0061609	fructose-1-phosphate aldolase activity	ALDOB	IDA		Human	PMID:2649152
Molecular Function	GO:0061609	fructose-1-phosphate aldolase activity	Aldob	IMP	MGI:MGI:4951216	Mouse	PMID:29533924
Molecular Function	GO:0061609	fructose-1-phosphate aldolase activity	Aldob	IMP	MGI:MGI:4951216	Mouse	PMID:25637246
Molecular Function	GO:0004332	fructose-bisphosphate aldolase activity	ALDOB	IDA		Human	PMID:10625657
Molecular Function	GO:0004332	fructose-bisphosphate aldolase activity	ALDOB	IDA		Human	PMID:17576770
Molecular Function	GO:0004332	fructose-bisphosphate aldolase activity	ALDOB	IDA		Human	PMID:9244396
Molecular Function	GO:0004332	fructose-bisphosphate aldolase activity	Aldob	IDA		Mouse	PMID:604178
Molecular Function	GO:0004332	fructose-bisphosphate aldolase activity	Aldob	IMP	MGI:MGI:4951216	Mouse	PMID:25637246
Molecular Function	GO:0004332	fructose-bisphosphate aldolase activity	Aldob	IDA		Rat	PMID:9448062|RGD:2302096
Molecular Function	GO:0042802	identical protein binding	ALDOB	IPI	UniProtKB:P05062	Human	PMID:10625657
Molecular Function	GO:0031210	phosphatidylcholine binding	Aldob	IPI	PubChem_Compound:6138	Rat	PMID:9448062|RGD:2302096
Molecular Function	GO:0005515	protein binding	ALDOB	IPI	UniProtKB:Q8IWZ6	Human	PMID:18000879
Molecular Function	GO:0005515	protein binding	ALDOB	IPI	UniProtKB:Q8NFJ9	Human	PMID:18000879
Molecular Function	GO:0005515	protein binding	ALDOB	IPI	UniProtKB:Q96RK4	Human	PMID:18000879
Molecular Function	GO:0005515	protein binding	ALDOB	IPI	UniProtKB:Q9BXC9	Human	PMID:18000879
Cellular Component	GO:0034451	centriolar satellite	ALDOB	IDA		Human	PMID:18000879
Cellular Component	GO:0005737	cytoplasm	Aldob	IDA		Rat	PMID:201371|RGD:2302783
Cellular Component	GO:0005829	cytosol	Aldob	IDA		Mouse	PMID:32733884
Cellular Component	GO:0005829	cytosol	Aldob	IDA		Rat	PMID:9886486|RGD:1599068
Cellular Component	GO:0070062	extracellular exosome	ALDOB	HDA		Human	PMID:23533145
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Aldob	IDA		Rat	PMID:15683743|RGD:2313418
Cellular Component	GO:0005764	lysosome	Aldob	IDA		Rat	PMID:9886486|RGD:1599068
Cellular Component	GO:0005815	microtubule organizing center	ALDOB	IDA		Human	PMID:18000879
Cellular Component	GO:0005634	nucleus	Aldob	IDA		Rat	PMID:10797566|RGD:1599066
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Aldob	IDA		Rat	PMID:10797566|RGD:1599066
Cellular Component	GO:0005886	plasma membrane	Aldob	IDA		Rat	PMID:10797566|RGD:1599066
Cellular Component	GO:0030867	rough endoplasmic reticulum membrane	Aldob	IDA		Rat	PMID:234468|RGD:2313431
Cellular Component	GO:0030868	smooth endoplasmic reticulum membrane	Aldob	IDA		Rat	PMID:234468|RGD:2313431
Biological Process	GO:0031668	cellular response to extracellular stimulus	Aldob	IEP		Rat	PMID:15770659|RGD:2313417
Biological Process	GO:0032869	cellular response to insulin stimulus	Aldob	IEP		Rat	PMID:9473304|RGD:1599069
Biological Process	GO:0030388	fructose 1,6-bisphosphate metabolic process	ALDOB	IDA		Human	PMID:10625657
Biological Process	GO:0030388	fructose 1,6-bisphosphate metabolic process	ALDOB	IDA		Human	PMID:9244396
Biological Process	GO:0006001	fructose catabolic process	Aldob	IMP	MGI:MGI:4951216	Mouse	PMID:29533924
Biological Process	GO:0006001	fructose catabolic process	Aldob	IDA		Mouse	PMID:4343087
Biological Process	GO:0061624	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate	Aldob	IMP	MGI:MGI:4951216	Mouse	PMID:29533924
Biological Process	GO:0006000	fructose metabolic process	ALDOB	IMP		Human	PMID:3383242
Biological Process	GO:0006096	glycolytic process	ALDOB	IDA		Human	PMID:10625657
Biological Process	GO:0001889	liver development	Aldob	IEP		Rat	PMID:8641049|RGD:2313428
Biological Process	GO:0006116	NADH oxidation	ALDOB	IDA		Human	PMID:17576770
Biological Process	GO:0032781	positive regulation of ATP-dependent activity	ALDOB	IGI		Human	PMID:17576770
Biological Process	GO:0043200	response to amino acid	Aldob	IEP		Rat	PMID:2984252|RGD:2313437
Biological Process	GO:0051591	response to cAMP	Aldob	IEP		Rat	PMID:2984252|RGD:2313437
Biological Process	GO:0009743	response to carbohydrate	Aldob	IEP		Rat	PMID:6689021|RGD:1599071
Biological Process	GO:0046688	response to copper ion	Aldob	IEP		Rat	PMID:11044632|RGD:1599065
Biological Process	GO:0009750	response to fructose	Aldob	IEP		Rat	PMID:2984252|RGD:2313437
Biological Process	GO:0051384	response to glucocorticoid	Aldob	IEP		Rat	PMID:9473304|RGD:1599069
Biological Process	GO:0070741	response to interleukin-6	Aldob	IEP		Rat	PMID:7625825|RGD:2313427
Biological Process	GO:0014070	response to organic cyclic compound	Aldob	IEP		Rat	PMID:9020521|RGD:1599070
Biological Process	GO:0043434	response to peptide hormone	Aldob	IDA		Rat	PMID:10775441|RGD:1599067
Biological Process	GO:0042594	response to starvation	Aldob	IEP		Rat	PMID:9886486|RGD:1599068
Biological Process	GO:0009410	response to xenobiotic stimulus	Aldob	IEP		Rat	PMID:12387752|RGD:2313419
Biological Process	GO:0010043	response to zinc ion	Aldob	IDA		Rat	PMID:12721403|RGD:1599064
Biological Process	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly	ALDOB	IGI		Human	PMID:17576770

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern