About   Help   FAQ
Aldob
Gene Detail
 Symbol
Name
ID
Aldob
aldolase B, fructose-bisphosphate
MGI:87995
Synonyms Aldo2, Aldo-2
Feature Type protein coding gene
Genetic Map
Chromosome 4
26.57 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr4:49535995-49549546 bp, - strand
From VEGA annotation of GRCm38

  13552 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20060  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: fructose-bisphosphate aldolase
Gene Tree: Aldob

Human
homologs
Human Homolog ALDOB, aldolase B, fructose-bisphosphate
NCBI Gene ID 229
neXtProt AC  NX_P05062
Human Synonyms  ALDB, ALDO2
Human Chr (Location)  9q21.3-q22.2; chr9:101420560-101435780 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human ALDOB
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Aldob interacts with 157 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (33 annotations)
Process fructose 1,6-bisphosphate metabolic process, fructose metabolic process, ...
Component centriolar satellite, cytoplasm, ...
Function ATPase binding, catalytic activity, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (204)    Tissues (155)    Images (28)
Theiler Stages: 22, 23, 26, 28
Assay TypeResults
RNA in situ 204
cDNA source data(934)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(937) Genomic(2) cDNA(934) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000008318 (Evidence)
Ensembl Gene ModelENSMUSG00000028307 (Evidence)
Entrez Gene230163 (Evidence)
UniGene482116
DFCITC1573722
DoTSDT.40138101, DT.97369232, DT.97416592, DT.99865794
NIA Mouse Gene IndexU025056
EC4.1.2.13
Consensus CDS ProjectCCDS18176.1
International Mouse Knockout Project StatusAldob
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008318 VEGA Gene Model | MGI Sequence Detail 13552 C57BL/6J ±  kb
transcript OTTMUST00000018935 VEGA | MGI Sequence Detail 2016 Not Applicable 
polypeptide OTTMUSP00000008705 VEGA | MGI Sequence Detail 364 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(2) UniProt(3)
Polymorphisms RFLP(1) : SNPs within 2kb(122 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013785 Aldolase-type TIM barrel
InterPro IPR000741 Fructose-bisphosphate aldolase, class-I
Protein Ontology PR:000003935 fructose-bisphosphate aldolase B
References (Earliest) J:35647 Stoltzner G, Effects of life-long dietary protein restriction on mortality, growth, organ weights, blood counts, liver aldolase and kidney catalase in Balb/C mice. Growth. 1977 Dec;41(4):337-48
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(45)
Other
accession IDs
MGD-MRK-1277, MGD-MRK-1279, MGI:2387622

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/23/2014
MGI 5.19
The Jackson Laboratory