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Aldob
Gene Detail
Symbol

Name
ID
Aldob
aldolase B, fructose-bisphosphate
MGI:87995
Synonyms
Aldo2, Aldo-2
Feature Type
protein coding gene
Genetic Map
Chromosome 4
26.57 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr4:49535995-49549546 bp, - strand
From VEGA annotation of GRCm38

  13552 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20060  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: ALDOB
Protein SuperFamily: fructose-bisphosphate aldolase
Gene Tree: Aldob

Human
homologs
ALDOB, aldolase B, fructose-bisphosphate
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 229
neXtProt AC: NX_P05062

Human Synonyms: ALDB, ALDO2

Human Chr (Location): 9q21.3-q22.2; chr9:101420560-101435780 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human ALDOB

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Aldob interacts with 157 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (33 annotations)
Process fructose 1,6-bisphosphate metabolic process, fructose metabolic process, ...
Component centriolar satellite, cytoplasm, ...
Function ATPase binding, catalytic activity, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (204)    Tissues (155)    Images (28)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 204
cDNA source data(934)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA ALDOB ; Xenbase aldob    NEW 
Molecular
reagents
All nucleic(937) Genomic(2) cDNA(934) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000008318 (Evidence)
Ensembl Gene Model ENSMUSG00000028307 (Evidence)
Entrez Gene 230163 (Evidence)
UniGene 482116
DFCI TC1573722
DoTS DT.40138101, DT.97369232, DT.97416592, DT.99865794
NIA Mouse Gene Index U025056
EC 4.1.2.13
Consensus CDS Project CCDS18176.1
International Mouse Phenotyping Consortium Status Aldob
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008318 VEGA Gene Model | MGI Sequence Detail 13552 C57BL/6J ±  kb
transcript OTTMUST00000018935 VEGA | MGI Sequence Detail 2016 Not Applicable 
polypeptide OTTMUSP00000008705 VEGA | MGI Sequence Detail 364 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(2) UniProt(3)
Polymorphisms
RFLP(1) : SNPs within 2kb(122 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013785 Aldolase-type TIM barrel
InterPro IPR000741 Fructose-bisphosphate aldolase, class-I
Protein Ontology PR:000003935 fructose-bisphosphate aldolase B
References
(Earliest) J:35647 Stoltzner G, Effects of life-long dietary protein restriction on mortality, growth, organ weights, blood counts, liver aldolase and kidney catalase in Balb/C mice. Growth. 1977 Dec;41(4):337-48
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(45)
Other
accession IDs
MGD-MRK-1277, MGD-MRK-1279, MGI:2387622

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory