Aldob
Gene Detail

Symbol

Name
ID

Aldob
aldolase B, fructose-bisphosphate
MGI:87995

Synonyms

Aldo2, Aldo-2

Feature Type

protein coding gene

Genetic Map

Chromosome 4
26.57 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr4:49535995-49549546 bp, - strand From VEGA annotation of GRCm38   13552 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:20060  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: fructose-bisphosphate aldolase
Gene Tree: Aldob

Human
homologs

Human Homolog		ALDOB, aldolase B, fructose-bisphosphate
NCBI Gene ID		229
neXtProt AC		NX_P05062
Human Synonyms		ALDB, ALDO2
Human Chr (Location)		9q21.3-q22.2; chr9:101420560-101435780 (-)  GRCh38
Disease Associations		(1) Diseases Associated with Human ALDOB

Mutations,
alleles, and
phenotypes

All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )

Interactions

Aldob interacts with 157 markers (Mir7-1, Mir7-2, Mir7b, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (33 annotations)

Process	fructose 1,6-bisphosphate metabolic process, fructose metabolic process, ...
Component	centriolar satellite, cytoplasm, ...
Function	ATPase binding, catalytic activity, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (6 records)

Data Summary: Results (204)    Tissues (155)    Images (28)    Tissue x Stage Matrix (view)

Assay Type	Results
RNA in situ	204

cDNA source data(934)
External Resources: Allen Institute   GEO   Expression Atlas

Molecular
reagents

All nucleic(937) Genomic(2) cDNA(934) Primer pair(1)
Microarray probesets(4)

Other database
links

VEGA Gene Model	OTTMUSG00000008318 (Evidence)
Ensembl Gene Model	ENSMUSG00000028307 (Evidence)
Entrez Gene	230163 (Evidence)
UniGene	482116
DFCI	TC1573722
DoTS	DT.40138101, DT.97369232, DT.97416592, DT.99865794
NIA Mouse Gene Index	U025056
EC	4.1.2.13
Consensus CDS Project	CCDS18176.1
International Mouse Knockout Project Status	Aldob

Sequences

Length	Strain/Species
genomic	OTTMUSG00000008318	VEGA Gene Model | MGI Sequence Detail	13552	C57BL/6J
transcript	OTTMUST00000018935	VEGA | MGI Sequence Detail	2016	Not Applicable
polypeptide	OTTMUSP00000008705	VEGA | MGI Sequence Detail	364	Not Applicable

All sequences(52) RefSeq(2) UniProt(5)

Polymorphisms

RFLP(1) : SNPs within 2kb(122 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR013785	Aldolase-type TIM barrel
InterPro	IPR000741	Fructose-bisphosphate aldolase, class-I
Protein Ontology	PR:000003935	fructose-bisphosphate aldolase B

References

(Earliest) J:35647 Stoltzner G, Effects of life-long dietary protein restriction on mortality, growth, organ weights, blood counts, liver aldolase and kidney catalase in Balb/C mice. Growth. 1977 Dec;41(4):337-48
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(46)

Other
accession IDs

MGD-MRK-1277, MGD-MRK-1279, MGI:2387622