Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Adm

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ADM
- Mouse genes Adm
- Rat genes Adm
- Zfish genes adma,admb
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adm

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031700	adrenomedullin receptor binding	ADM	IDA		Human	PMID:20074556
Molecular Function	GO:0031700	adrenomedullin receptor binding	Adm	IDA		Rat	PMID:7592696\|RGD:61533
Molecular Function	GO:0005515	protein binding	Adm	IPI	UniProtKB:O60895	Rat	PMID:9620797\|RGD:8553905
Cellular Component	GO:0005737	cytoplasm	ADM	IDA		Human	PMID:12379507
Cellular Component	GO:0005615	extracellular space	ADM	IDA		Human	PMID:12379507
Cellular Component	GO:0005615	extracellular space	Adm	IDA		Rat	PMID:16174584\|RGD:1625328
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ADM	IDA		Human	PMID:10882736
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ADM	IDA		Human	PMID:18434369
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ADM	IDA		Human	PMID:20074556
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ADM	IGI	ComplexPortal:CPX-2173\|UniProtKB:O60894,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ADM	IGI	ComplexPortal:CPX-3186\|UniProtKB:O60895,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:1990410	adrenomedullin receptor signaling pathway	ADM	IDA		Human	PMID:10882736
Biological Process	GO:1990410	adrenomedullin receptor signaling pathway	ADM	IDA		Human	PMID:18434369
Biological Process	GO:1990410	adrenomedullin receptor signaling pathway	ADM	IDA		Human	PMID:20074556
Biological Process	GO:0007568	aging	Adm	IEP		Rat	PMID:17301036\|RGD:1625311
Biological Process	GO:0007568	aging	Adm	IEP		Rat	PMID:18166684\|RGD:2325638
Biological Process	GO:0097647	amylin receptor signaling pathway	ADM	IGI	ComplexPortal:CPX-3186	Human	PMID:22500019
Biological Process	GO:0097647	amylin receptor signaling pathway	ADM	IGI	UniProtKB:O60894,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:0097647	amylin receptor signaling pathway	ADM	IGI	UniProtKB:O60895,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:0008209	androgen metabolic process	Adm	IDA		Rat	PMID:18094363\|RGD:2325639
Biological Process	GO:0031100	animal organ regeneration	Adm	IEP		Rat	PMID:16077951\|RGD:1625331
Biological Process	GO:0060670	branching involved in labyrinthine layer morphogenesis	Adm	IMP	MGI:MGI:2176598	Mouse	PMID:16981008
Biological Process	GO:0055074	calcium ion homeostasis	Adm	IMP		Rat	PMID:17766482\|RGD:1642599
Biological Process	GO:0019933	cAMP-mediated signaling	Adm	IEP		Rat	PMID:12193565\|RGD:628358
Biological Process	GO:0008283	cell population proliferation	Adm	IMP	MGI:MGI:2176598	Mouse	PMID:16537897
Biological Process	GO:0048589	developmental growth	Adm	IMP	MGI:MGI:2176598	Mouse	PMID:16981008
Biological Process	GO:0007565	female pregnancy	Adm	IEP		Rat	PMID:16260338\|RGD:1625327
Biological Process	GO:0002031	G protein-coupled receptor internalization	ADM	IDA		Human	PMID:10882736
Biological Process	GO:0007507	heart development	Adm	IMP		Mouse	MGI:MGI:3772552\|PMID:18097473
Biological Process	GO:0007507	heart development	Adm	IMP	MGI:MGI:2176598	Mouse	PMID:16537897
Biological Process	GO:0007507	heart development	Adm	IMP	MGI:MGI:2176598	Mouse	PMID:16981008
Biological Process	GO:0046879	hormone secretion	Adm	IMP		Rat	PMID:19723921\|RGD:2325631
Biological Process	GO:0008285	negative regulation of cell population proliferation	Adm	IMP		Rat	PMID:16157033\|RGD:1625329
Biological Process	GO:0043116	negative regulation of vascular permeability	Adm	IMP		Mouse	MGI:MGI:3772552\|PMID:18097473
Biological Process	GO:0045906	negative regulation of vasoconstriction	ADM	IDA		Human	PMID:11410113
Biological Process	GO:0001843	neural tube closure	Adm	IMP	MGI:MGI:2176598	Mouse	PMID:16981008
Biological Process	GO:0031102	neuron projection regeneration	Adm	IMP		Rat	PMID:17101235\|RGD:1625313
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Adm	IEP		Rat	PMID:19828015\|RGD:2325629
Biological Process	GO:0045766	positive regulation of angiogenesis	Adm	IMP		Mouse	MGI:MGI:3772552\|PMID:18097473
Biological Process	GO:0043065	positive regulation of apoptotic process	Adm	IMP		Rat	PMID:15229133\|RGD:1625332
Biological Process	GO:0008284	positive regulation of cell population proliferation	Adm	IMP	MGI:MGI:2176598	Mouse	PMID:16537897
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Adm	IDA		Rat	PMID:17446268\|RGD:1625306
Biological Process	GO:0010460	positive regulation of heart rate	ADM	IDA		Human	PMID:18434369
Biological Process	GO:0010460	positive regulation of heart rate	Adm	IDA		Rat	PMID:19520650\|RGD:2325635
Biological Process	GO:2001214	positive regulation of vasculogenesis	Adm	IMP		Mouse	MGI:MGI:3772552\|PMID:18097473
Biological Process	GO:0031623	receptor internalization	ADM	IDA		Human	PMID:10882736
Biological Process	GO:0031623	receptor internalization	ADM	IDA		Human	PMID:15613468
Biological Process	GO:0031623	receptor internalization	ADM	IDA		Human	PMID:20074556
Biological Process	GO:0003073	regulation of systemic arterial blood pressure	ADM	IDA		Human	PMID:18434369
Biological Process	GO:0002026	regulation of the force of heart contraction	Adm	IDA		Rat	PMID:19520650\|RGD:2325635
Biological Process	GO:0035809	regulation of urine volume	ADM	IDA		Human	PMID:18434369
Biological Process	GO:0009409	response to cold	Adm	IEP		Rat	PMID:16432587\|RGD:1625324
Biological Process	GO:0051384	response to glucocorticoid	Adm	IEP		Rat	PMID:16735801\|RGD:1625317
Biological Process	GO:0001666	response to hypoxia	Adm	IEP		Rat	PMID:17251392\|RGD:1625295
Biological Process	GO:0032868	response to insulin	Adm	IEP		Rat	PMID:17327422\|RGD:1625308
Biological Process	GO:0032496	response to lipopolysaccharide	Adm	IMP		Rat	PMID:16378176\|RGD:1625325
Biological Process	GO:0010033	response to organic substance	Adm	IEP		Rat	PMID:16278779\|RGD:1625326
Biological Process	GO:0042594	response to starvation	Adm	IEP		Rat	PMID:17335899\|RGD:1625307
Biological Process	GO:0009611	response to wounding	Adm	IDA		Rat	PMID:12193565\|RGD:628358
Biological Process	GO:0060712	spongiotrophoblast layer development	Adm	IMP	MGI:MGI:2176598	Mouse	PMID:16981008
Biological Process	GO:0097084	vascular associated smooth muscle cell development	Adm	IMP		Mouse	MGI:MGI:3772552\|PMID:18097473
Biological Process	GO:0001570	vasculogenesis	ADM	IDA		Human	PMID:16964401

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.