About   Help   FAQ
Gene Ontology Browser
Term Detail
GO term:receptor internalization
GO id:GO:0031623
Definition:A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane.
Number of paths to term: 11

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-areceptor metabolic process
                                                is-alow-density lipoprotein receptor particle metabolic process +
                                                is-aneurotransmitter receptor metabolic process +
                                                is-areceptor biosynthetic process +
                                                is-areceptor catabolic process +
                                                is-areceptor internalization [GO:0031623] (83 genes, 100 annotations)
                                                        is-aB cell receptor internalization +
                                                        is-aG-protein coupled receptor internalization +
                                                        is-ainsulin receptor internalization +
                                                        negatively-regulatesnegative regulation of receptor internalization +
                                                        is-aneurotransmitter receptor internalization +
                                                        positively-regulatespositive regulation of receptor internalization +
                                                        is-areceptor internalization involved in canonical Wnt signaling pathway
                                                        regulatesregulation of receptor internalization +
                                                        is-aregulation of signal transduction by receptor internalization +
                                                        is-aWnt receptor internalization +
                                                is-areceptor recycling +


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-a(+)-kotanin metabolic process +
                                is-a(-)-microperfuranone metabolic process +
                                is-a3-hydroxybenzyl alcohol metabolic process
                                is-a3alpha(S)-strictosidine biosynthetic process
                                is-a3alpha(S)-strictosidine catabolic process
                                is-a6-alpha-maltosylglucose metabolic process +
                                is-aacetyl-CoA biosynthetic process from ethanol
                                is-aacetylcholine metabolic process +
                                is-aactin cortical patch organization +
                                is-aactin filament-based process +
                                is-aalditol metabolic process +
                                is-aalpha-ribazole metabolic process +
                                is-aaminoglycoside antibiotic biosynthetic process +
                                is-aaminoglycoside antibiotic catabolic process +
                                is-aangiotensin catabolic process in blood
                                is-aansamycin metabolic process +
                                is-aaromatic primary alcohol metabolic process +
                                is-aascospore wall chitin metabolic process +
                                is-aaspyridone A metabolic process +
                                is-aaspyridone B metabolic process +
                                is-abacillithiol metabolic process +
                                is-abeta-1,2-oligomannoside metabolic process +
                                is-ablood microparticle formation +
                                is-abrevianamide F metabolic process +
                                is-aC21-steroid hormone metabolic process +
                                is-acarbon fixation by acetyl-CoA pathway
                                is-acargo loading into vesicle +
                                is-acell activation +
                                is-acell adhesion molecule production +
                                is-acell communication +
                                is-acell competition in a multicellular organism
                                is-acell cycle +
                                is-acell death +
                                is-acell division +
                                is-acell growth +
                                is-acell junction organization +
                                is-acell projection organization +
                                is-acell recognition +
                                is-acell wall beta-glucan metabolic process +
                                is-acellular alcohol metabolic process +
                                is-acellular aldehyde metabolic process +
                                is-acellular alkane metabolic process +
                                is-acellular alkyne metabolic process +
                                is-acellular carbohydrate biosynthetic process +
                                is-acellular component assembly involved in morphogenesis +
                                is-acellular component disassembly +
                                is-acellular component maintenance +
                                is-acellular developmental process +
                                is-acellular homeostasis +
                                is-acellular ketone body metabolic process +
                                is-acellular ketone metabolic process +
                                is-acellular lactam metabolic process +
                                is-acellular lipid metabolic process +
                                is-acellular oligosaccharide metabolic process +
                                is-acellular pigmentation +
                                is-acellular potassium ion transport +
                                is-acellular process involved in reproduction in multicellular organism +
                                is-achanoclavine-I metabolic process +
                                is-achlorophyll biosynthetic process +
                                is-achlorophyll catabolic process +
                                is-achromosome number maintenance
                                is-achromosome segregation +
                                is-acobalamin metabolic process +
                                is-acoenzyme M metabolic process +
                                is-aconiferin metabolic process
                                is-acontact inhibition +
                                is-acordyol C metabolic process +
                                is-acyanide metabolic process +
                                is-acyanogenic glycoside biosynthetic process +
                                is-acyanogenic glycoside catabolic process
                                is-acyclohexanol metabolic process +
                                is-acytoplasm organization +
                                is-aD-arabinose catabolic process to xylulose 5-phosphate
                                is-ademethylkotanin metabolic process +
                                is-adibenzo-p-dioxin metabolic process +
                                is-adibenzofuran metabolic process +
                                is-adimethyl ether metabolic process
                                is-adimethyl sulfoxide metabolic process
                                is-adimethylsilanediol metabolic process +
                                is-adiorcinol metabolic process +
                                is-adisaccharide metabolic process +
                                is-aDNA clamp unloading
                                is-aDNA demethylation +
                                is-aelectron transport chain +
                                is-aemericellamide metabolic process +
                                is-aenergy derivation by oxidation of organic compounds +
                                is-aenergy derivation by oxidation of reduced inorganic compounds +
                                is-aensheathment of neurons +
                                is-aepoxide metabolic process +
                                is-aERAD pathway +
                                is-aergot alkaloid biosynthetic process +
                                is-aergot alkaloid catabolic process +
                                is-aestablishment or maintenance of cell polarity +
                                is-aestablishment or maintenance of cell type involved in phenotypic switching
                                is-aethanolamine-containing compound metabolic process +
                                is-aexecution phase of apoptosis +
                                is-aexecution phase of necroptosis
                                is-aextracellular structure organization +
                                is-aF-9775A metabolic process +
                                is-aF-9775B metabolic process +
                                is-afumitremorgin B metabolic process +
                                is-aGDP-mannose biosynthetic process from mannose
                                is-agene silencing +
                                is-aglucuronoside metabolic process +
                                is-aglutathione derivative metabolic process +
                                is-aglycerol ether biosynthetic process +
                                is-aglycerol ether catabolic process
                                is-ahalogenated hydrocarbon metabolic process +
                                is-aheme metabolic process +
                                is-ainositol metabolic process +
                                is-ainositol phosphate metabolic process +
                                is-aintermediate filament-based process +
                                is-aL-arabinose catabolic process to xylulose 5-phosphate
                                is-aleukotriene D4 metabolic process +
                                is-alight absorption +
                                is-amacrolide metabolic process +
                                is-amaintenance of blood-brain barrier
                                is-amaintenance of location in cell +
                                is-amannose to fructose-6-phosphate metabolic process
                                is-amelanin metabolic process +
                                is-amembrane docking +
                                is-amethyl tert-butyl ether metabolic process
                                is-amicrotubule organizing center attachment site organization
                                is-amicrotubule-based process +
                                is-amineralocorticoid metabolic process +
                                is-amovement of cell or subcellular component +
                                is-amycothiol metabolic process +
                                is-anicotinamide metabolic process +
                                is-anucleobase-containing small molecule metabolic process +
                                is-anucleoid organization +
                                is-aommochrome metabolic process +
                                is-aone-carbon metabolic process +
                                is-aorcinol metabolic process +
                                is-aorganic acid metabolic process +
                                is-aorlandin metabolic process +
                                is-aoxidative RNA demethylation +
                                is-aoxytetracycline metabolic process +
                                is-apeptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine
                                is-aperiplasmic space organization
                                is-aphenolic phthiocerol biosynthetic process
                                is-aphenylpropanoid metabolic process +
                                is-apheromone metabolic process +
                                is-aphytochelatin metabolic process +
                                is-aplasma lipoprotein particle organization +
                                is-aplasmid maintenance +
                                is-aplastoglobule organization
                                is-apolythionate oxidation
                                is-aprotein demethylation +
                                is-aprotein glycosylation +
                                is-aprotein halogenation +
                                is-aprotein oxidation +
                                is-apteridine biosynthetic process
                                is-areceptor internalization [GO:0031623] (83 genes, 100 annotations)
                                        is-aB cell receptor internalization +
                                        is-aG-protein coupled receptor internalization +
                                        is-ainsulin receptor internalization +
                                        negatively-regulatesnegative regulation of receptor internalization +
                                        is-aneurotransmitter receptor internalization +
                                        positively-regulatespositive regulation of receptor internalization +
                                        is-areceptor internalization involved in canonical Wnt signaling pathway
                                        regulatesregulation of receptor internalization +
                                        is-aregulation of signal transduction by receptor internalization +
                                        is-aWnt receptor internalization +
                                is-aregulation of cellular component size +
                                is-aregulation of translational initiation by eIF2 alpha dephosphorylation +
                                is-arhamnogalacturonan I biosynthetic process
                                is-arhodopsin metabolic process +
                                is-ariboflavin metabolic process +
                                is-aS-glycoside metabolic process +
                                is-asecretion by cell +
                                is-asiderophore metabolic process +
                                is-asignal maturation +
                                is-asignal transduction by protein phosphorylation +
                                is-asingle-organism intercellular transport +
                                is-asingle-organism membrane organization +
                                is-asingle-organism organelle organization +
                                is-astomatal movement +
                                is-asulfate reduction +
                                is-asulfide oxidation +
                                is-asulfur oxidation +
                                is-asynapse organization +
                                is-asyncytium formation +
                                is-atensidol A metabolic process +
                                is-aterminal button organization +
                                is-atetracycline metabolic process +
                                is-athiamine-containing compound metabolic process +
                                is-atoluene oxidation +
                                is-atoxin metabolic process +
                                is-atransposition +
                                is-aurea metabolic process +
                                is-averruculogen metabolic process +
                                is-avesicle targeting +
                                is-avindoline metabolic process +
                                is-aviolaceol I metabolic process +
                                is-aviolaceol II metabolic process +
                                is-avistamycin metabolic process +
                                is-avitamin B6 metabolic process +
                                is-avitamin biosynthetic process +
                                is-avitamin catabolic process +
                                is-avitamin E metabolic process +
                                is-awybutosine biosynthetic process


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-asingle-organism transport
                                                is-a2-aminoethylphosphonate transport
                                                is-aacetate ester transport +
                                                is-aalkane transport
                                                is-acalcium ion transport into cytosol +
                                                is-acarbohydrate derivative transport +
                                                is-acarbohydrate transport +
                                                is-acargo loading into vesicle +
                                                is-acellular potassium ion transport +
                                                is-achaperone-mediated protein transport +
                                                is-acofactor transport +
                                                is-acutin transport
                                                is-aDNA import into cell involved in transformation
                                                is-adrug transport +
                                                is-adsRNA transport
                                                is-aendosome to plasma membrane protein transport +
                                                is-aeye pigment precursor transport
                                                is-afatty acid derivative transport
                                                is-afatty-acyl group transport
                                                is-afluid transport +
                                                is-agas transport +
                                                is-aGolgi to plasma membrane protein transport +
                                                is-ahormone transport +
                                                is-ahydrogen transport +
                                                is-aintermembrane transport +
                                                is-airon coordination entity transport +
                                                is-alactone transport
                                                is-alipid hydroperoxide transport
                                                is-alipid transport +
                                                is-alipoprotein transport
                                                is-amonoamine transport +
                                                is-amultivesicular body sorting pathway
                                                is-aneurotransmitter receptor transport to plasma membrane +
                                                is-aneurotransmitter transport +
                                                is-anitric oxide transport
                                                is-anucleobase transport +
                                                is-aone-carbon compound transport +
                                                is-aorganic acid transport +
                                                is-aorganic hydroxy compound transport +
                                                is-aorganic phosphonate transport +
                                                is-aorganophosphate ester transport +
                                                is-aovarian nurse cell to oocyte transport +
                                                is-aphagocytosis +
                                                is-apigment granule transport +
                                                is-apolyamine transport +
                                                is-aprotein import +
                                                is-aprotein transport across periplasmic space +
                                                is-aprotein transport within extracellular region
                                                is-aquaternary ammonium group transport +
                                                is-areceptor internalization [GO:0031623] (83 genes, 100 annotations)
                                                        is-aB cell receptor internalization +
                                                        is-aG-protein coupled receptor internalization +
                                                        is-ainsulin receptor internalization +
                                                        negatively-regulatesnegative regulation of receptor internalization +
                                                        is-aneurotransmitter receptor internalization +
                                                        positively-regulatespositive regulation of receptor internalization +
                                                        is-areceptor internalization involved in canonical Wnt signaling pathway
                                                        regulatesregulation of receptor internalization +
                                                        is-aregulation of signal transduction by receptor internalization +
                                                        is-aWnt receptor internalization +
                                                is-arRNA transport +
                                                is-asecretion +
                                                is-asilicate transport
                                                is-asingle-organism intercellular transport +
                                                is-asingle-organism intracellular transport +
                                                is-asingle-organism pinocytosis +
                                                is-asnRNA transport +
                                                is-asperm entry
                                                is-asulfur compound transport +
                                                is-asynaptic vesicle transport +
                                                is-atranscytosis +
                                                is-atransepithelial transport +
                                                is-atRNA transport +
                                                is-aubiquitin-dependent endocytosis +
                                                is-avascular transport +
                                                is-avesicle targeting, cis-Golgi to rough ER +
                                                is-avesicle-mediated transport involved in floral organ abscission +
                                                is-avitamin transport +
                                                is-axenobiotic transport +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-avesicle-mediated transport
                                                is-aendocytosis
                                                        is-areceptor-mediated endocytosis
                                                                is-aclathrin-dependent endocytosis +
                                                                negatively-regulatesnegative regulation of receptor-mediated endocytosis +
                                                                positively-regulatespositive regulation of receptor-mediated endocytosis +
                                                                is-areceptor internalization [GO:0031623] (83 genes, 100 annotations)
                                                                        is-aB cell receptor internalization +
                                                                        is-aG-protein coupled receptor internalization +
                                                                        is-ainsulin receptor internalization +
                                                                        negatively-regulatesnegative regulation of receptor internalization +
                                                                        is-aneurotransmitter receptor internalization +
                                                                        positively-regulatespositive regulation of receptor internalization +
                                                                        is-areceptor internalization involved in canonical Wnt signaling pathway
                                                                        regulatesregulation of receptor internalization +
                                                                        is-aregulation of signal transduction by receptor internalization +
                                                                        is-aWnt receptor internalization +
                                                                is-areceptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport
                                                                is-areceptor-mediated endocytosis of virus by host cell +
                                                                regulatesregulation of receptor-mediated endocytosis +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-asingle-organism localization
                                is-asingle-organism transport
                                        is-a2-aminoethylphosphonate transport
                                        is-aacetate ester transport +
                                        is-aalkane transport
                                        is-acalcium ion transport into cytosol +
                                        is-acarbohydrate derivative transport +
                                        is-acarbohydrate transport +
                                        is-acargo loading into vesicle +
                                        is-acellular potassium ion transport +
                                        is-achaperone-mediated protein transport +
                                        is-acofactor transport +
                                        is-acutin transport
                                        is-aDNA import into cell involved in transformation
                                        is-adrug transport +
                                        is-adsRNA transport
                                        is-aendosome to plasma membrane protein transport +
                                        is-aeye pigment precursor transport
                                        is-afatty acid derivative transport
                                        is-afatty-acyl group transport
                                        is-afluid transport +
                                        is-agas transport +
                                        is-aGolgi to plasma membrane protein transport +
                                        is-ahormone transport +
                                        is-ahydrogen transport +
                                        is-aintermembrane transport +
                                        is-airon coordination entity transport +
                                        is-alactone transport
                                        is-alipid hydroperoxide transport
                                        is-alipid transport +
                                        is-alipoprotein transport
                                        is-amonoamine transport +
                                        is-amultivesicular body sorting pathway
                                        is-aneurotransmitter receptor transport to plasma membrane +
                                        is-aneurotransmitter transport +
                                        is-anitric oxide transport
                                        is-anucleobase transport +
                                        is-aone-carbon compound transport +
                                        is-aorganic acid transport +
                                        is-aorganic hydroxy compound transport +
                                        is-aorganic phosphonate transport +
                                        is-aorganophosphate ester transport +
                                        is-aovarian nurse cell to oocyte transport +
                                        is-aphagocytosis +
                                        is-apigment granule transport +
                                        is-apolyamine transport +
                                        is-aprotein import +
                                        is-aprotein transport across periplasmic space +
                                        is-aprotein transport within extracellular region
                                        is-aquaternary ammonium group transport +
                                        is-areceptor internalization [GO:0031623] (83 genes, 100 annotations)
                                                is-aB cell receptor internalization +
                                                is-aG-protein coupled receptor internalization +
                                                is-ainsulin receptor internalization +
                                                negatively-regulatesnegative regulation of receptor internalization +
                                                is-aneurotransmitter receptor internalization +
                                                positively-regulatespositive regulation of receptor internalization +
                                                is-areceptor internalization involved in canonical Wnt signaling pathway
                                                regulatesregulation of receptor internalization +
                                                is-aregulation of signal transduction by receptor internalization +
                                                is-aWnt receptor internalization +
                                        is-arRNA transport +
                                        is-asecretion +
                                        is-asilicate transport
                                        is-asingle-organism intercellular transport +
                                        is-asingle-organism intracellular transport +
                                        is-asingle-organism pinocytosis +
                                        is-asnRNA transport +
                                        is-asperm entry
                                        is-asulfur compound transport +
                                        is-asynaptic vesicle transport +
                                        is-atranscytosis +
                                        is-atransepithelial transport +
                                        is-atRNA transport +
                                        is-aubiquitin-dependent endocytosis +
                                        is-avascular transport +
                                        is-avesicle targeting, cis-Golgi to rough ER +
                                        is-avesicle-mediated transport involved in floral organ abscission +
                                        is-avitamin transport +
                                        is-axenobiotic transport +


obsolete Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-areceptor metabolic process
                                                is-alow-density lipoprotein receptor particle metabolic process +
                                                is-aneurotransmitter receptor metabolic process +
                                                is-areceptor biosynthetic process +
                                                is-areceptor catabolic process +
                                                is-areceptor internalization [GO:0031623] (83 genes, 100 annotations)
                                                        is-aB cell receptor internalization +
                                                        is-aG-protein coupled receptor internalization +
                                                        is-ainsulin receptor internalization +
                                                        negatively-regulatesnegative regulation of receptor internalization +
                                                        is-aneurotransmitter receptor internalization +
                                                        positively-regulatespositive regulation of receptor internalization +
                                                        is-areceptor internalization involved in canonical Wnt signaling pathway
                                                        regulatesregulation of receptor internalization +
                                                        is-aregulation of signal transduction by receptor internalization +
                                                        is-aWnt receptor internalization +
                                                is-areceptor recycling +


obsolete Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-acellular macromolecule metabolic process
                                                is-areceptor metabolic process
                                                        is-alow-density lipoprotein receptor particle metabolic process +
                                                        is-aneurotransmitter receptor metabolic process +
                                                        is-areceptor biosynthetic process +
                                                        is-areceptor catabolic process +
                                                        is-areceptor internalization [GO:0031623] (83 genes, 100 annotations)
                                                                is-aB cell receptor internalization +
                                                                is-aG-protein coupled receptor internalization +
                                                                is-ainsulin receptor internalization +
                                                                negatively-regulatesnegative regulation of receptor internalization +
                                                                is-aneurotransmitter receptor internalization +
                                                                positively-regulatespositive regulation of receptor internalization +
                                                                is-areceptor internalization involved in canonical Wnt signaling pathway
                                                                regulatesregulation of receptor internalization +
                                                                is-aregulation of signal transduction by receptor internalization +
                                                                is-aWnt receptor internalization +
                                                        is-areceptor recycling +


obsolete Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-asingle-organism metabolic process
                                is-aacetate ester metabolic process +
                                is-aactin modification +
                                is-aalkanesulfonate metabolic process +
                                is-aamyloid fibril formation
                                is-aaustinol metabolic process +
                                is-acarbon fixation +
                                is-acellular aldehyde metabolic process +
                                is-acellular alkane metabolic process +
                                is-acellular alkyne metabolic process +
                                is-acoenzyme M metabolic process +
                                is-acyanide metabolic process +
                                is-ademethylation +
                                is-adimethyl sulfoxide metabolic process
                                is-aDNA protection
                                is-aepidermal growth factor receptor ligand maturation +
                                is-afatty acid derivative metabolic process +
                                is-aglutathione derivative metabolic process +
                                is-aglycosyl compound metabolic process +
                                is-aglycosylation +
                                is-ahalogenated hydrocarbon metabolic process +
                                is-aisotype switching +
                                is-alipid metabolic process +
                                is-amethylation-dependent chromatin silencing +
                                is-amulticellular organism metabolic process +
                                is-aoxidation-reduction process +
                                is-apatched ligand maturation
                                is-apigment metabolic process +
                                is-areceptor internalization [GO:0031623] (83 genes, 100 annotations)
                                        is-aB cell receptor internalization +
                                        is-aG-protein coupled receptor internalization +
                                        is-ainsulin receptor internalization +
                                        negatively-regulatesnegative regulation of receptor internalization +
                                        is-aneurotransmitter receptor internalization +
                                        positively-regulatespositive regulation of receptor internalization +
                                        is-areceptor internalization involved in canonical Wnt signaling pathway
                                        regulatesregulation of receptor internalization +
                                        is-aregulation of signal transduction by receptor internalization +
                                        is-aWnt receptor internalization +
                                is-aregulation of translational initiation by eIF2 alpha dephosphorylation +
                                is-arespiratory burst +
                                is-aRNA-directed DNA methylation
                                is-asecondary metabolic process +
                                is-asignal transduction by protein phosphorylation +
                                is-asingle-organism biosynthetic process +
                                is-asingle-organism carbohydrate metabolic process +
                                is-asingle-organism catabolic process +
                                is-asmall molecule metabolic process +
                                is-atartrate metabolic process +
                                is-atelomere maintenance via semi-conservative replication +
                                is-atransposition, DNA-mediated +
                                is-atransposon integration +
                                is-atRNA methylation in response to nitrogen starvation +


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-a(+)-kotanin metabolic process +
                                is-a(-)-microperfuranone metabolic process +
                                is-a3-hydroxybenzyl alcohol metabolic process
                                is-a3alpha(S)-strictosidine biosynthetic process
                                is-a3alpha(S)-strictosidine catabolic process
                                is-a6-alpha-maltosylglucose metabolic process +
                                is-aacetyl-CoA biosynthetic process from ethanol
                                is-aacetylcholine metabolic process +
                                is-aactin cortical patch organization +
                                is-aactin filament-based process +
                                is-aalditol metabolic process +
                                is-aalpha-ribazole metabolic process +
                                is-aaminoglycoside antibiotic biosynthetic process +
                                is-aaminoglycoside antibiotic catabolic process +
                                is-aangiotensin catabolic process in blood
                                is-aansamycin metabolic process +
                                is-aaromatic primary alcohol metabolic process +
                                is-aascospore wall chitin metabolic process +
                                is-aaspyridone A metabolic process +
                                is-aaspyridone B metabolic process +
                                is-abacillithiol metabolic process +
                                is-abeta-1,2-oligomannoside metabolic process +
                                is-ablood microparticle formation +
                                is-abrevianamide F metabolic process +
                                is-aC21-steroid hormone metabolic process +
                                is-acarbon fixation by acetyl-CoA pathway
                                is-acargo loading into vesicle +
                                is-acell activation +
                                is-acell adhesion molecule production +
                                is-acell communication +
                                is-acell competition in a multicellular organism
                                is-acell cycle +
                                is-acell death +
                                is-acell division +
                                is-acell growth +
                                is-acell junction organization +
                                is-acell projection organization +
                                is-acell recognition +
                                is-acell wall beta-glucan metabolic process +
                                is-acellular alcohol metabolic process +
                                is-acellular aldehyde metabolic process +
                                is-acellular alkane metabolic process +
                                is-acellular alkyne metabolic process +
                                is-acellular carbohydrate biosynthetic process +
                                is-acellular component assembly involved in morphogenesis +
                                is-acellular component disassembly +
                                is-acellular component maintenance +
                                is-acellular developmental process +
                                is-acellular homeostasis +
                                is-acellular ketone body metabolic process +
                                is-acellular ketone metabolic process +
                                is-acellular lactam metabolic process +
                                is-acellular lipid metabolic process +
                                is-acellular oligosaccharide metabolic process +
                                is-acellular pigmentation +
                                is-acellular potassium ion transport +
                                is-acellular process involved in reproduction in multicellular organism +
                                is-achanoclavine-I metabolic process +
                                is-achlorophyll biosynthetic process +
                                is-achlorophyll catabolic process +
                                is-achromosome number maintenance
                                is-achromosome segregation +
                                is-acobalamin metabolic process +
                                is-acoenzyme M metabolic process +
                                is-aconiferin metabolic process
                                is-acontact inhibition +
                                is-acordyol C metabolic process +
                                is-acyanide metabolic process +
                                is-acyanogenic glycoside biosynthetic process +
                                is-acyanogenic glycoside catabolic process
                                is-acyclohexanol metabolic process +
                                is-acytoplasm organization +
                                is-aD-arabinose catabolic process to xylulose 5-phosphate
                                is-ademethylkotanin metabolic process +
                                is-adibenzo-p-dioxin metabolic process +
                                is-adibenzofuran metabolic process +
                                is-adimethyl ether metabolic process
                                is-adimethyl sulfoxide metabolic process
                                is-adimethylsilanediol metabolic process +
                                is-adiorcinol metabolic process +
                                is-adisaccharide metabolic process +
                                is-aDNA clamp unloading
                                is-aDNA demethylation +
                                is-aelectron transport chain +
                                is-aemericellamide metabolic process +
                                is-aenergy derivation by oxidation of organic compounds +
                                is-aenergy derivation by oxidation of reduced inorganic compounds +
                                is-aensheathment of neurons +
                                is-aepoxide metabolic process +
                                is-aERAD pathway +
                                is-aergot alkaloid biosynthetic process +
                                is-aergot alkaloid catabolic process +
                                is-aestablishment or maintenance of cell polarity +
                                is-aestablishment or maintenance of cell type involved in phenotypic switching
                                is-aethanolamine-containing compound metabolic process +
                                is-aexecution phase of apoptosis +
                                is-aexecution phase of necroptosis
                                is-aextracellular structure organization +
                                is-aF-9775A metabolic process +
                                is-aF-9775B metabolic process +
                                is-afumitremorgin B metabolic process +
                                is-aGDP-mannose biosynthetic process from mannose
                                is-agene silencing +
                                is-aglucuronoside metabolic process +
                                is-aglutathione derivative metabolic process +
                                is-aglycerol ether biosynthetic process +
                                is-aglycerol ether catabolic process
                                is-ahalogenated hydrocarbon metabolic process +
                                is-aheme metabolic process +
                                is-ainositol metabolic process +
                                is-ainositol phosphate metabolic process +
                                is-aintermediate filament-based process +
                                is-aL-arabinose catabolic process to xylulose 5-phosphate
                                is-aleukotriene D4 metabolic process +
                                is-alight absorption +
                                is-amacrolide metabolic process +
                                is-amaintenance of blood-brain barrier
                                is-amaintenance of location in cell +
                                is-amannose to fructose-6-phosphate metabolic process
                                is-amelanin metabolic process +
                                is-amembrane docking +
                                is-amethyl tert-butyl ether metabolic process
                                is-amicrotubule organizing center attachment site organization
                                is-amicrotubule-based process +
                                is-amineralocorticoid metabolic process +
                                is-amovement of cell or subcellular component +
                                is-amycothiol metabolic process +
                                is-anicotinamide metabolic process +
                                is-anucleobase-containing small molecule metabolic process +
                                is-anucleoid organization +
                                is-aommochrome metabolic process +
                                is-aone-carbon metabolic process +
                                is-aorcinol metabolic process +
                                is-aorganic acid metabolic process +
                                is-aorlandin metabolic process +
                                is-aoxidative RNA demethylation +
                                is-aoxytetracycline metabolic process +
                                is-apeptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine
                                is-aperiplasmic space organization
                                is-aphenolic phthiocerol biosynthetic process
                                is-aphenylpropanoid metabolic process +
                                is-apheromone metabolic process +
                                is-aphytochelatin metabolic process +
                                is-aplasma lipoprotein particle organization +
                                is-aplasmid maintenance +
                                is-aplastoglobule organization
                                is-apolythionate oxidation
                                is-aprotein demethylation +
                                is-aprotein glycosylation +
                                is-aprotein halogenation +
                                is-aprotein oxidation +
                                is-apteridine biosynthetic process
                                is-areceptor internalization [GO:0031623] (83 genes, 100 annotations)
                                        is-aB cell receptor internalization +
                                        is-aG-protein coupled receptor internalization +
                                        is-ainsulin receptor internalization +
                                        negatively-regulatesnegative regulation of receptor internalization +
                                        is-aneurotransmitter receptor internalization +
                                        positively-regulatespositive regulation of receptor internalization +
                                        is-areceptor internalization involved in canonical Wnt signaling pathway
                                        regulatesregulation of receptor internalization +
                                        is-aregulation of signal transduction by receptor internalization +
                                        is-aWnt receptor internalization +
                                is-aregulation of cellular component size +
                                is-aregulation of translational initiation by eIF2 alpha dephosphorylation +
                                is-arhamnogalacturonan I biosynthetic process
                                is-arhodopsin metabolic process +
                                is-ariboflavin metabolic process +
                                is-aS-glycoside metabolic process +
                                is-asecretion by cell +
                                is-asiderophore metabolic process +
                                is-asignal maturation +
                                is-asignal transduction by protein phosphorylation +
                                is-asingle-organism intercellular transport +
                                is-asingle-organism membrane organization +
                                is-asingle-organism organelle organization +
                                is-astomatal movement +
                                is-asulfate reduction +
                                is-asulfide oxidation +
                                is-asulfur oxidation +
                                is-asynapse organization +
                                is-asyncytium formation +
                                is-atensidol A metabolic process +
                                is-aterminal button organization +
                                is-atetracycline metabolic process +
                                is-athiamine-containing compound metabolic process +
                                is-atoluene oxidation +
                                is-atoxin metabolic process +
                                is-atransposition +
                                is-aurea metabolic process +
                                is-averruculogen metabolic process +
                                is-avesicle targeting +
                                is-avindoline metabolic process +
                                is-aviolaceol I metabolic process +
                                is-aviolaceol II metabolic process +
                                is-avistamycin metabolic process +
                                is-avitamin B6 metabolic process +
                                is-avitamin biosynthetic process +
                                is-avitamin catabolic process +
                                is-avitamin E metabolic process +
                                is-awybutosine biosynthetic process


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism localization
                                is-asingle-organism transport
                                        is-a2-aminoethylphosphonate transport
                                        is-aacetate ester transport +
                                        is-aalkane transport
                                        is-acalcium ion transport into cytosol +
                                        is-acarbohydrate derivative transport +
                                        is-acarbohydrate transport +
                                        is-acargo loading into vesicle +
                                        is-acellular potassium ion transport +
                                        is-achaperone-mediated protein transport +
                                        is-acofactor transport +
                                        is-acutin transport
                                        is-aDNA import into cell involved in transformation
                                        is-adrug transport +
                                        is-adsRNA transport
                                        is-aendosome to plasma membrane protein transport +
                                        is-aeye pigment precursor transport
                                        is-afatty acid derivative transport
                                        is-afatty-acyl group transport
                                        is-afluid transport +
                                        is-agas transport +
                                        is-aGolgi to plasma membrane protein transport +
                                        is-ahormone transport +
                                        is-ahydrogen transport +
                                        is-aintermembrane transport +
                                        is-airon coordination entity transport +
                                        is-alactone transport
                                        is-alipid hydroperoxide transport
                                        is-alipid transport +
                                        is-alipoprotein transport
                                        is-amonoamine transport +
                                        is-amultivesicular body sorting pathway
                                        is-aneurotransmitter receptor transport to plasma membrane +
                                        is-aneurotransmitter transport +
                                        is-anitric oxide transport
                                        is-anucleobase transport +
                                        is-aone-carbon compound transport +
                                        is-aorganic acid transport +
                                        is-aorganic hydroxy compound transport +
                                        is-aorganic phosphonate transport +
                                        is-aorganophosphate ester transport +
                                        is-aovarian nurse cell to oocyte transport +
                                        is-aphagocytosis +
                                        is-apigment granule transport +
                                        is-apolyamine transport +
                                        is-aprotein import +
                                        is-aprotein transport across periplasmic space +
                                        is-aprotein transport within extracellular region
                                        is-aquaternary ammonium group transport +
                                        is-areceptor internalization [GO:0031623] (83 genes, 100 annotations)
                                                is-aB cell receptor internalization +
                                                is-aG-protein coupled receptor internalization +
                                                is-ainsulin receptor internalization +
                                                negatively-regulatesnegative regulation of receptor internalization +
                                                is-aneurotransmitter receptor internalization +
                                                positively-regulatespositive regulation of receptor internalization +
                                                is-areceptor internalization involved in canonical Wnt signaling pathway
                                                regulatesregulation of receptor internalization +
                                                is-aregulation of signal transduction by receptor internalization +
                                                is-aWnt receptor internalization +
                                        is-arRNA transport +
                                        is-asecretion +
                                        is-asilicate transport
                                        is-asingle-organism intercellular transport +
                                        is-asingle-organism intracellular transport +
                                        is-asingle-organism pinocytosis +
                                        is-asnRNA transport +
                                        is-asperm entry
                                        is-asulfur compound transport +
                                        is-asynaptic vesicle transport +
                                        is-atranscytosis +
                                        is-atransepithelial transport +
                                        is-atRNA transport +
                                        is-aubiquitin-dependent endocytosis +
                                        is-avascular transport +
                                        is-avesicle targeting, cis-Golgi to rough ER +
                                        is-avesicle-mediated transport involved in floral organ abscission +
                                        is-avitamin transport +
                                        is-axenobiotic transport +


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism metabolic process
                                is-aacetate ester metabolic process +
                                is-aactin modification +
                                is-aalkanesulfonate metabolic process +
                                is-aamyloid fibril formation
                                is-aaustinol metabolic process +
                                is-acarbon fixation +
                                is-acellular aldehyde metabolic process +
                                is-acellular alkane metabolic process +
                                is-acellular alkyne metabolic process +
                                is-acoenzyme M metabolic process +
                                is-acyanide metabolic process +
                                is-ademethylation +
                                is-adimethyl sulfoxide metabolic process
                                is-aDNA protection
                                is-aepidermal growth factor receptor ligand maturation +
                                is-afatty acid derivative metabolic process +
                                is-aglutathione derivative metabolic process +
                                is-aglycosyl compound metabolic process +
                                is-aglycosylation +
                                is-ahalogenated hydrocarbon metabolic process +
                                is-aisotype switching +
                                is-alipid metabolic process +
                                is-amethylation-dependent chromatin silencing +
                                is-amulticellular organism metabolic process +
                                is-aoxidation-reduction process +
                                is-apatched ligand maturation
                                is-apigment metabolic process +
                                is-areceptor internalization [GO:0031623] (83 genes, 100 annotations)
                                        is-aB cell receptor internalization +
                                        is-aG-protein coupled receptor internalization +
                                        is-ainsulin receptor internalization +
                                        negatively-regulatesnegative regulation of receptor internalization +
                                        is-aneurotransmitter receptor internalization +
                                        positively-regulatespositive regulation of receptor internalization +
                                        is-areceptor internalization involved in canonical Wnt signaling pathway
                                        regulatesregulation of receptor internalization +
                                        is-aregulation of signal transduction by receptor internalization +
                                        is-aWnt receptor internalization +
                                is-aregulation of translational initiation by eIF2 alpha dephosphorylation +
                                is-arespiratory burst +
                                is-aRNA-directed DNA methylation
                                is-asecondary metabolic process +
                                is-asignal transduction by protein phosphorylation +
                                is-asingle-organism biosynthetic process +
                                is-asingle-organism carbohydrate metabolic process +
                                is-asingle-organism catabolic process +
                                is-asmall molecule metabolic process +
                                is-atartrate metabolic process +
                                is-atelomere maintenance via semi-conservative replication +
                                is-atransposition, DNA-mediated +
                                is-atransposon integration +
                                is-atRNA methylation in response to nitrogen starvation +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/20/2016
MGI 6.05
The Jackson Laboratory