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Gene Ontology Browser
Term Detail
GO term:receptor internalization
GO id:GO:0031623
Definition:A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane.
Number of paths to term: 12

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-areceptor metabolic process
                                                is-alow-density lipoprotein receptor particle metabolic process +
                                                is-aneurotransmitter receptor metabolic process +
                                                is-areceptor biosynthetic process +
                                                is-areceptor catabolic process +
                                                is-areceptor internalization [GO:0031623] (62 genes, 70 annotations)
                                                        is-aB cell receptor internalization +
                                                        is-aG-protein coupled receptor internalization
                                                        is-ainsulin receptor internalization +
                                                        negatively-regulatesnegative regulation of receptor internalization
                                                        positively-regulatespositive regulation of receptor internalization
                                                        is-areceptor internalization involved in canonical Wnt signaling pathway
                                                        regulatesregulation of receptor internalization +
                                                        is-aregulation of signal transduction by receptor internalization +
                                                        is-aWnt receptor internalization +
                                                is-areceptor recycling +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-a(+)-kotanin metabolic process +
                                is-a(-)-microperfuranone metabolic process +
                                is-a3-hydroxybenzyl alcohol metabolic process
                                is-a3alpha(S)-strictosidine biosynthetic process
                                is-a3alpha(S)-strictosidine catabolic process
                                is-a6-alpha-maltosylglucose metabolic process +
                                is-aacetyl-CoA biosynthetic process from ethanol
                                is-aacetylcholine metabolic process +
                                is-aactin cortical patch organization +
                                is-aactin filament-based process +
                                is-aalditol metabolic process +
                                is-aalkanesulfonate metabolic process +
                                is-aalpha-ribazole metabolic process +
                                is-aaminoglycoside antibiotic biosynthetic process +
                                is-aaminoglycoside antibiotic catabolic process +
                                is-aandrogen metabolic process +
                                is-aansamycin metabolic process +
                                is-aaromatic primary alcohol metabolic process +
                                is-aascospore wall chitin metabolic process +
                                is-aaspyridone A metabolic process +
                                is-aaspyridone B metabolic process +
                                is-aautolysis
                                is-aautophagy in response to ER overload
                                is-abeta-1,2-oligomannoside metabolic process +
                                is-ablood microparticle formation +
                                is-abrevianamide F metabolic process +
                                is-aC21-steroid hormone metabolic process +
                                is-acarbon fixation by acetyl-CoA pathway
                                is-acell activation +
                                is-acell adhesion molecule production +
                                is-acell aging +
                                is-acell communication +
                                is-acell competition in a multicellular organism
                                is-acell cycle +
                                is-acell cycle process +
                                is-acell death +
                                is-acell division +
                                is-acell growth +
                                is-acell junction organization +
                                is-acell projection organization +
                                is-acell recognition +
                                is-acell wall beta-glucan metabolic process +
                                is-acellular alcohol metabolic process +
                                is-acellular aldehyde metabolic process +
                                is-acellular alkane metabolic process +
                                is-acellular alkyne metabolic process +
                                is-acellular carbohydrate biosynthetic process +
                                is-acellular component disassembly +
                                is-acellular component maintenance +
                                is-acellular component movement +
                                is-acellular detoxification of nitrogen compound
                                is-acellular developmental process +
                                is-acellular homeostasis +
                                is-acellular ketone body metabolic process +
                                is-acellular ketone metabolic process +
                                is-acellular lactam metabolic process +
                                is-acellular lipid metabolic process +
                                is-acellular oligosaccharide metabolic process +
                                is-acellular pigmentation +
                                is-acellular potassium ion transport +
                                is-achanoclavine-I metabolic process +
                                is-achlorophyll biosynthetic process +
                                is-achlorophyll catabolic process +
                                is-achromosome number maintenance
                                is-achromosome segregation +
                                is-acobalamin metabolic process +
                                is-acoenzyme M metabolic process +
                                is-aconiferin metabolic process
                                is-acontact inhibition +
                                is-acordyol C metabolic process +
                                is-acyanide metabolic process +
                                is-acyclohexanol metabolic process +
                                is-acytoplasm organization +
                                is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                is-aD-arabinose catabolic process to xylulose 5-phosphate
                                is-adefense response by callose deposition in cell wall
                                is-ademethylkotanin metabolic process +
                                is-adendritic spine organization +
                                is-adhurrin biosynthetic process
                                is-adibenzo-p-dioxin metabolic process +
                                is-adibenzofuran metabolic process +
                                is-adimethyl ether metabolic process
                                is-adimethyl sulfoxide metabolic process
                                is-adimethylsilanediol metabolic process +
                                is-adiorcinol metabolic process +
                                is-adisaccharide metabolic process +
                                is-aDNA damage induced protein phosphorylation
                                is-aDNA demethylation +
                                is-aDNA repair +
                                is-adsRNA fragmentation +
                                is-aelectron transport chain +
                                is-aemericellamide metabolic process +
                                is-aenergy derivation by oxidation of organic compounds +
                                is-aenergy derivation by oxidation of reduced inorganic compounds +
                                is-aensheathment of neurons +
                                is-aEntner-Doudoroff pathway
                                is-aepithelial cell proliferation involved in prostate gland development +
                                is-aepoxide metabolic process +
                                is-aER-associated misfolded protein catabolic process
                                is-aergot alkaloid biosynthetic process +
                                is-aergot alkaloid catabolic process +
                                is-aestablishment or maintenance of cell polarity +
                                is-aestablishment or maintenance of cell type involved in phenotypic switching
                                is-aestrogen metabolic process +
                                is-aethanolamine-containing compound metabolic process +
                                is-aexecution phase of apoptosis +
                                is-aexecution phase of necroptosis
                                is-aextracellular structure organization +
                                is-aF-9775A metabolic process +
                                is-aF-9775B metabolic process +
                                is-afibril organization +
                                is-afumitremorgin B metabolic process +
                                is-agalactose to glucose-1-phosphate metabolic process
                                is-agene silencing +
                                is-aglucose import in response to insulin stimulus +
                                is-aglycerol ether biosynthetic process +
                                is-aglycerol ether catabolic process
                                is-aglycolytic process +
                                is-ahalogenated hydrocarbon metabolic process +
                                is-aheme metabolic process +
                                is-ahydrogen peroxide catabolic process +
                                is-ainositol metabolic process +
                                is-ainositol phosphate metabolic process +
                                is-aintermediate filament-based process +
                                is-aL-arabinose catabolic process to xylulose 5-phosphate
                                is-alight absorption +
                                is-amacrolide metabolic process +
                                is-amaintenance of blood-brain barrier
                                is-amaintenance of location in cell +
                                is-amannose to fructose-6-phosphate metabolic process
                                is-aMAPK import into nucleus involved in conjugation with cellular fusion
                                is-aMAPK import into nucleus involved in innate immune response
                                is-amelanin metabolic process +
                                is-amembrane docking +
                                is-amesenchymal cell proliferation involved in prostate gland development +
                                is-amethyl tert-butyl ether metabolic process
                                is-amicroautophagy +
                                is-amicrotubule organizing center attachment site organization
                                is-amicrotubule-based process +
                                is-amineralocorticoid metabolic process +
                                is-amRNA export from nucleus in response to heat stress +
                                is-amycothiol metabolic process +
                                is-anicotinamide metabolic process +
                                is-anucleobase-containing small molecule metabolic process +
                                is-anucleoid organization +
                                is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                is-aommochrome metabolic process +
                                is-aone-carbon metabolic process +
                                is-aorcinol metabolic process +
                                is-aorganic acid metabolic process +
                                is-aorlandin metabolic process +
                                is-aoxidative RNA demethylation +
                                is-aoxytetracycline metabolic process +
                                is-apeptide pheromone export involved in conjugation with cellular fusion
                                is-apeptidoglycan biosynthetic process +
                                is-apeptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine
                                is-aperiplasmic space organization
                                is-aphenolic phthiocerol biosynthetic process
                                is-aphenylpropanoid metabolic process +
                                is-apheromone metabolic process +
                                is-aphotoreceptor cell outer segment organization
                                is-aphytochelatin metabolic process +
                                is-aphytol salvage
                                is-aplasma membrane fusion +
                                is-aplasma membrane organization involved in conjugation with cellular fusion
                                is-aplasmid maintenance +
                                is-aplastoglobule organization
                                is-apollen adhesion
                                is-apollen wall assembly +
                                is-apolythionate oxidation
                                is-apronuclear envelope synthesis +
                                is-aprotein demethylation +
                                is-aprotein glycosylation +
                                is-aprotein halogenation +
                                is-aprotein oxidation +
                                is-apteridine biosynthetic process
                                is-areceptor internalization [GO:0031623] (62 genes, 70 annotations)
                                        is-aB cell receptor internalization +
                                        is-aG-protein coupled receptor internalization
                                        is-ainsulin receptor internalization +
                                        negatively-regulatesnegative regulation of receptor internalization
                                        positively-regulatespositive regulation of receptor internalization
                                        is-areceptor internalization involved in canonical Wnt signaling pathway
                                        regulatesregulation of receptor internalization +
                                        is-aregulation of signal transduction by receptor internalization +
                                        is-aWnt receptor internalization +
                                is-aregulation of cellular component size +
                                is-aregulation of translational initiation by eIF2 alpha phosphorylation +
                                is-aremoval of superoxide radicals +
                                is-areplication fork processing +
                                is-areversion of cell type to default state involved in phenotypic switching
                                is-arhamnogalacturonan I biosynthetic process
                                is-arhodopsin metabolic process +
                                is-ariboflavin metabolic process +
                                is-aS-glycoside metabolic process +
                                is-asecretion by cell +
                                is-aSertoli cell proliferation
                                is-asiderophore metabolic process +
                                is-asignal maturation +
                                is-asignal transduction by phosphorylation +
                                is-asingle-celled organism vegetative growth phase +
                                is-asingle-organism intercellular transport +
                                is-asingle-organism organelle organization +
                                is-aspecification of ureteric bud anterior/posterior symmetry by BMP signaling pathway
                                is-asperm entry
                                is-aspore wall assembly +
                                is-astomatal movement +
                                is-asulfate reduction +
                                is-asulfide oxidation +
                                is-asulfur oxidation +
                                is-asynapse organization +
                                is-asyncytium formation +
                                is-atensidol A metabolic process +
                                is-aterminal button organization +
                                is-atetracycline metabolic process +
                                is-athiamine-containing compound metabolic process +
                                is-atoluene oxidation +
                                is-atoxin metabolic process +
                                is-atransmembrane transport +
                                is-atransposition +
                                is-aurea metabolic process +
                                is-averruculogen metabolic process +
                                is-avesicle targeting +
                                is-avesicle-mediated transport involved in floral organ abscission +
                                is-aviolaceol I metabolic process +
                                is-aviolaceol II metabolic process +
                                is-avistamycin metabolic process +
                                is-avitamin B6 metabolic process +
                                is-avitamin biosynthetic process +
                                is-avitamin catabolic process +
                                is-avitamin E metabolic process +
                                is-awybutosine biosynthetic process


Gene_Ontology
        is-abiological_process
                is-aestablishment of localization
                        is-atransport
                                is-asingle-organism transport
                                        is-a2-aminoethylphosphonate transport
                                        is-aacetate ester transport +
                                        is-aalkane transport
                                        is-aamide transport +
                                        is-aamine transport +
                                        is-acarbohydrate derivative transport +
                                        is-acarbohydrate transport +
                                        is-acargo loading into vesicle +
                                        is-achaperone-mediated protein transport +
                                        is-acofactor transport +
                                        is-acutin transport
                                        is-aDNA import into cell involved in transformation
                                        is-adrug transport +
                                        is-adsRNA transport
                                        is-aeye pigment precursor transport
                                        is-afatty acid derivative transport +
                                        is-afatty-acyl group transport
                                        is-afluid transport +
                                        is-agas transport +
                                        is-aglycoside transport +
                                        is-ahormone transport +
                                        is-ahydrogen transport +
                                        is-aintestinal absorption +
                                        is-aion transport +
                                        is-airon coordination entity transport +
                                        is-alactone transport
                                        is-alipid hydroperoxide transport
                                        is-alipid transport +
                                        is-alipoprotein transport
                                        is-amonoamine transport +
                                        is-amultivesicular body sorting pathway
                                        is-aneurotransmitter transport +
                                        is-anitric oxide transport
                                        is-anucleobase transport +
                                        is-aone-carbon compound transport +
                                        is-aorganic acid transport +
                                        is-aorganic hydroxy compound transport +
                                        is-aorganic phosphonate transport +
                                        is-aorganophosphate ester transport +
                                        is-aovarian nurse cell to oocyte transport +
                                        is-aphagocytosis +
                                        is-apigment granule transport +
                                        is-apolyamine transport +
                                        is-aprotein import +
                                        is-aprotein transport across periplasmic space +
                                        is-aprotein transport within extracellular region
                                        is-aquaternary ammonium group transport +
                                        is-areceptor internalization [GO:0031623] (62 genes, 70 annotations)
                                                is-aB cell receptor internalization +
                                                is-aG-protein coupled receptor internalization
                                                is-ainsulin receptor internalization +
                                                negatively-regulatesnegative regulation of receptor internalization
                                                positively-regulatespositive regulation of receptor internalization
                                                is-areceptor internalization involved in canonical Wnt signaling pathway
                                                regulatesregulation of receptor internalization +
                                                is-aregulation of signal transduction by receptor internalization +
                                                is-aWnt receptor internalization +
                                        is-areceptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport
                                        is-arRNA transport +
                                        is-asecretion +
                                        is-asilicate transport +
                                        is-asingle-organism intercellular transport +
                                        is-asingle-organism intracellular transport +
                                        is-asingle-organism pinocytosis +
                                        is-asnRNA transport +
                                        is-asperm entry
                                        is-asulfur compound transport +
                                        is-asynaptic vesicle transport +
                                        is-athioester transport +
                                        is-atranscytosis +
                                        is-atransepithelial transport +
                                        is-atransmembrane transport +
                                        is-atRNA transport +
                                        is-aubiquitin-dependent endocytosis +
                                        is-avascular transport +
                                        is-avesicle transport along actin filament
                                        is-avesicle-mediated transport involved in floral organ abscission +
                                        is-avitamin transport +
                                        is-axenobiotic transport +


Gene_Ontology
        is-abiological_process
                is-aestablishment of localization
                        is-atransport
                                is-avesicle-mediated transport
                                        is-aendocytosis
                                                is-areceptor-mediated endocytosis
                                                        is-acaveolin-mediated endocytosis +
                                                        is-aclathrin-mediated endocytosis +
                                                        negatively-regulatesnegative regulation of receptor-mediated endocytosis +
                                                        positively-regulatespositive regulation of receptor-mediated endocytosis +
                                                        is-areceptor internalization [GO:0031623] (62 genes, 70 annotations)
                                                                is-aB cell receptor internalization +
                                                                is-aG-protein coupled receptor internalization
                                                                is-ainsulin receptor internalization +
                                                                negatively-regulatesnegative regulation of receptor internalization
                                                                positively-regulatespositive regulation of receptor internalization
                                                                is-areceptor internalization involved in canonical Wnt signaling pathway
                                                                regulatesregulation of receptor internalization +
                                                                is-aregulation of signal transduction by receptor internalization +
                                                                is-aWnt receptor internalization +
                                                        is-areceptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport
                                                        is-areceptor-mediated endocytosis of virus by host cell +
                                                        regulatesregulation of receptor-mediated endocytosis +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        part-ofestablishment of localization
                                is-atransport
                                        is-asingle-organism transport
                                                is-a2-aminoethylphosphonate transport
                                                is-aacetate ester transport +
                                                is-aalkane transport
                                                is-aamide transport +
                                                is-aamine transport +
                                                is-acarbohydrate derivative transport +
                                                is-acarbohydrate transport +
                                                is-acargo loading into vesicle +
                                                is-achaperone-mediated protein transport +
                                                is-acofactor transport +
                                                is-acutin transport
                                                is-aDNA import into cell involved in transformation
                                                is-adrug transport +
                                                is-adsRNA transport
                                                is-aeye pigment precursor transport
                                                is-afatty acid derivative transport +
                                                is-afatty-acyl group transport
                                                is-afluid transport +
                                                is-agas transport +
                                                is-aglycoside transport +
                                                is-ahormone transport +
                                                is-ahydrogen transport +
                                                is-aintestinal absorption +
                                                is-aion transport +
                                                is-airon coordination entity transport +
                                                is-alactone transport
                                                is-alipid hydroperoxide transport
                                                is-alipid transport +
                                                is-alipoprotein transport
                                                is-amonoamine transport +
                                                is-amultivesicular body sorting pathway
                                                is-aneurotransmitter transport +
                                                is-anitric oxide transport
                                                is-anucleobase transport +
                                                is-aone-carbon compound transport +
                                                is-aorganic acid transport +
                                                is-aorganic hydroxy compound transport +
                                                is-aorganic phosphonate transport +
                                                is-aorganophosphate ester transport +
                                                is-aovarian nurse cell to oocyte transport +
                                                is-aphagocytosis +
                                                is-apigment granule transport +
                                                is-apolyamine transport +
                                                is-aprotein import +
                                                is-aprotein transport across periplasmic space +
                                                is-aprotein transport within extracellular region
                                                is-aquaternary ammonium group transport +
                                                is-areceptor internalization [GO:0031623] (62 genes, 70 annotations)
                                                        is-aB cell receptor internalization +
                                                        is-aG-protein coupled receptor internalization
                                                        is-ainsulin receptor internalization +
                                                        negatively-regulatesnegative regulation of receptor internalization
                                                        positively-regulatespositive regulation of receptor internalization
                                                        is-areceptor internalization involved in canonical Wnt signaling pathway
                                                        regulatesregulation of receptor internalization +
                                                        is-aregulation of signal transduction by receptor internalization +
                                                        is-aWnt receptor internalization +
                                                is-areceptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport
                                                is-arRNA transport +
                                                is-asecretion +
                                                is-asilicate transport +
                                                is-asingle-organism intercellular transport +
                                                is-asingle-organism intracellular transport +
                                                is-asingle-organism pinocytosis +
                                                is-asnRNA transport +
                                                is-asperm entry
                                                is-asulfur compound transport +
                                                is-asynaptic vesicle transport +
                                                is-athioester transport +
                                                is-atranscytosis +
                                                is-atransepithelial transport +
                                                is-atransmembrane transport +
                                                is-atRNA transport +
                                                is-aubiquitin-dependent endocytosis +
                                                is-avascular transport +
                                                is-avesicle transport along actin filament
                                                is-avesicle-mediated transport involved in floral organ abscission +
                                                is-avitamin transport +
                                                is-axenobiotic transport +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        part-ofestablishment of localization
                                is-atransport
                                        is-avesicle-mediated transport
                                                is-aendocytosis
                                                        is-areceptor-mediated endocytosis
                                                                is-acaveolin-mediated endocytosis +
                                                                is-aclathrin-mediated endocytosis +
                                                                negatively-regulatesnegative regulation of receptor-mediated endocytosis +
                                                                positively-regulatespositive regulation of receptor-mediated endocytosis +
                                                                is-areceptor internalization [GO:0031623] (62 genes, 70 annotations)
                                                                        is-aB cell receptor internalization +
                                                                        is-aG-protein coupled receptor internalization
                                                                        is-ainsulin receptor internalization +
                                                                        negatively-regulatesnegative regulation of receptor internalization
                                                                        positively-regulatespositive regulation of receptor internalization
                                                                        is-areceptor internalization involved in canonical Wnt signaling pathway
                                                                        regulatesregulation of receptor internalization +
                                                                        is-aregulation of signal transduction by receptor internalization +
                                                                        is-aWnt receptor internalization +
                                                                is-areceptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport
                                                                is-areceptor-mediated endocytosis of virus by host cell +
                                                                regulatesregulation of receptor-mediated endocytosis +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-areceptor metabolic process
                                                is-alow-density lipoprotein receptor particle metabolic process +
                                                is-aneurotransmitter receptor metabolic process +
                                                is-areceptor biosynthetic process +
                                                is-areceptor catabolic process +
                                                is-areceptor internalization [GO:0031623] (62 genes, 70 annotations)
                                                        is-aB cell receptor internalization +
                                                        is-aG-protein coupled receptor internalization
                                                        is-ainsulin receptor internalization +
                                                        negatively-regulatesnegative regulation of receptor internalization
                                                        positively-regulatespositive regulation of receptor internalization
                                                        is-areceptor internalization involved in canonical Wnt signaling pathway
                                                        regulatesregulation of receptor internalization +
                                                        is-aregulation of signal transduction by receptor internalization +
                                                        is-aWnt receptor internalization +
                                                is-areceptor recycling +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-acellular macromolecule metabolic process
                                                is-areceptor metabolic process
                                                        is-alow-density lipoprotein receptor particle metabolic process +
                                                        is-aneurotransmitter receptor metabolic process +
                                                        is-areceptor biosynthetic process +
                                                        is-areceptor catabolic process +
                                                        is-areceptor internalization [GO:0031623] (62 genes, 70 annotations)
                                                                is-aB cell receptor internalization +
                                                                is-aG-protein coupled receptor internalization
                                                                is-ainsulin receptor internalization +
                                                                negatively-regulatesnegative regulation of receptor internalization
                                                                positively-regulatespositive regulation of receptor internalization
                                                                is-areceptor internalization involved in canonical Wnt signaling pathway
                                                                regulatesregulation of receptor internalization +
                                                                is-aregulation of signal transduction by receptor internalization +
                                                                is-aWnt receptor internalization +
                                                        is-areceptor recycling +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-asingle-organism metabolic process
                                is-aacetate ester metabolic process +
                                is-aactin modification +
                                is-aalkanesulfonate metabolic process +
                                is-aamyloid fibril formation
                                is-aaustinol metabolic process +
                                is-acarbon fixation +
                                is-acellular aldehyde metabolic process +
                                is-acellular alkane metabolic process +
                                is-acellular alkyne metabolic process +
                                is-acellular detoxification of nitrogen compound
                                is-achromosome condensation +
                                is-acoenzyme M metabolic process +
                                is-acyanide metabolic process +
                                is-ademethylation +
                                is-adimethyl sulfoxide metabolic process
                                is-aDNA damage induced protein phosphorylation
                                is-aDNA protection
                                is-aDNA repair +
                                is-adsRNA fragmentation +
                                is-aepidermal growth factor receptor ligand maturation +
                                is-afatty acid derivative metabolic process +
                                is-aglutathione derivative metabolic process +
                                is-aglycosyl compound metabolic process +
                                is-ahalogenated hydrocarbon metabolic process +
                                is-ahistone modification +
                                is-aisotype switching +
                                is-alipid metabolic process +
                                is-amaintenance of DNA repeat elements +
                                is-amating type switching +
                                is-ameiotic DNA double-strand break formation +
                                is-ameiotic gene conversion +
                                is-ameiotic heteroduplex formation
                                is-ameiotic strand displacement +
                                is-ameiotic strand invasion +
                                is-amitochondrial RNA processing +
                                is-amulticellular organismal metabolic process +
                                is-aoxidation-reduction process +
                                is-apatched ligand maturation
                                is-apigment metabolic process +
                                is-aprotein activation cascade +
                                is-areceptor internalization [GO:0031623] (62 genes, 70 annotations)
                                        is-aB cell receptor internalization +
                                        is-aG-protein coupled receptor internalization
                                        is-ainsulin receptor internalization +
                                        negatively-regulatesnegative regulation of receptor internalization
                                        positively-regulatespositive regulation of receptor internalization
                                        is-areceptor internalization involved in canonical Wnt signaling pathway
                                        regulatesregulation of receptor internalization +
                                        is-aregulation of signal transduction by receptor internalization +
                                        is-aWnt receptor internalization +
                                is-areciprocal meiotic recombination +
                                is-aregulation of translational initiation by eIF2 alpha phosphorylation +
                                is-aremoval of superoxide radicals +
                                is-areplication fork processing +
                                is-arespiratory burst +
                                is-aRNA-directed DNA methylation
                                is-asecondary metabolic process +
                                is-asignal transduction by phosphorylation +
                                is-asingle-organism biosynthetic process +
                                is-asingle-organism carbohydrate metabolic process +
                                is-asingle-organism catabolic process +
                                is-asmall molecule metabolic process +
                                is-asperm chromatin condensation +
                                is-atartrate metabolic process +
                                is-atelomere maintenance +
                                is-atransposition, DNA-mediated +
                                is-atransposon integration +
                                is-atRNA methylation in response to nitrogen starvation +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-a(+)-kotanin metabolic process +
                                is-a(-)-microperfuranone metabolic process +
                                is-a3-hydroxybenzyl alcohol metabolic process
                                is-a3alpha(S)-strictosidine biosynthetic process
                                is-a3alpha(S)-strictosidine catabolic process
                                is-a6-alpha-maltosylglucose metabolic process +
                                is-aacetyl-CoA biosynthetic process from ethanol
                                is-aacetylcholine metabolic process +
                                is-aactin cortical patch organization +
                                is-aactin filament-based process +
                                is-aalditol metabolic process +
                                is-aalkanesulfonate metabolic process +
                                is-aalpha-ribazole metabolic process +
                                is-aaminoglycoside antibiotic biosynthetic process +
                                is-aaminoglycoside antibiotic catabolic process +
                                is-aandrogen metabolic process +
                                is-aansamycin metabolic process +
                                is-aaromatic primary alcohol metabolic process +
                                is-aascospore wall chitin metabolic process +
                                is-aaspyridone A metabolic process +
                                is-aaspyridone B metabolic process +
                                is-aautolysis
                                is-aautophagy in response to ER overload
                                is-abeta-1,2-oligomannoside metabolic process +
                                is-ablood microparticle formation +
                                is-abrevianamide F metabolic process +
                                is-aC21-steroid hormone metabolic process +
                                is-acarbon fixation by acetyl-CoA pathway
                                is-acell activation +
                                is-acell adhesion molecule production +
                                is-acell aging +
                                is-acell communication +
                                is-acell competition in a multicellular organism
                                is-acell cycle +
                                is-acell cycle process +
                                is-acell death +
                                is-acell division +
                                is-acell growth +
                                is-acell junction organization +
                                is-acell projection organization +
                                is-acell recognition +
                                is-acell wall beta-glucan metabolic process +
                                is-acellular alcohol metabolic process +
                                is-acellular aldehyde metabolic process +
                                is-acellular alkane metabolic process +
                                is-acellular alkyne metabolic process +
                                is-acellular carbohydrate biosynthetic process +
                                is-acellular component disassembly +
                                is-acellular component maintenance +
                                is-acellular component movement +
                                is-acellular detoxification of nitrogen compound
                                is-acellular developmental process +
                                is-acellular homeostasis +
                                is-acellular ketone body metabolic process +
                                is-acellular ketone metabolic process +
                                is-acellular lactam metabolic process +
                                is-acellular lipid metabolic process +
                                is-acellular oligosaccharide metabolic process +
                                is-acellular pigmentation +
                                is-acellular potassium ion transport +
                                is-achanoclavine-I metabolic process +
                                is-achlorophyll biosynthetic process +
                                is-achlorophyll catabolic process +
                                is-achromosome number maintenance
                                is-achromosome segregation +
                                is-acobalamin metabolic process +
                                is-acoenzyme M metabolic process +
                                is-aconiferin metabolic process
                                is-acontact inhibition +
                                is-acordyol C metabolic process +
                                is-acyanide metabolic process +
                                is-acyclohexanol metabolic process +
                                is-acytoplasm organization +
                                is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                is-aD-arabinose catabolic process to xylulose 5-phosphate
                                is-adefense response by callose deposition in cell wall
                                is-ademethylkotanin metabolic process +
                                is-adendritic spine organization +
                                is-adhurrin biosynthetic process
                                is-adibenzo-p-dioxin metabolic process +
                                is-adibenzofuran metabolic process +
                                is-adimethyl ether metabolic process
                                is-adimethyl sulfoxide metabolic process
                                is-adimethylsilanediol metabolic process +
                                is-adiorcinol metabolic process +
                                is-adisaccharide metabolic process +
                                is-aDNA damage induced protein phosphorylation
                                is-aDNA demethylation +
                                is-aDNA repair +
                                is-adsRNA fragmentation +
                                is-aelectron transport chain +
                                is-aemericellamide metabolic process +
                                is-aenergy derivation by oxidation of organic compounds +
                                is-aenergy derivation by oxidation of reduced inorganic compounds +
                                is-aensheathment of neurons +
                                is-aEntner-Doudoroff pathway
                                is-aepithelial cell proliferation involved in prostate gland development +
                                is-aepoxide metabolic process +
                                is-aER-associated misfolded protein catabolic process
                                is-aergot alkaloid biosynthetic process +
                                is-aergot alkaloid catabolic process +
                                is-aestablishment or maintenance of cell polarity +
                                is-aestablishment or maintenance of cell type involved in phenotypic switching
                                is-aestrogen metabolic process +
                                is-aethanolamine-containing compound metabolic process +
                                is-aexecution phase of apoptosis +
                                is-aexecution phase of necroptosis
                                is-aextracellular structure organization +
                                is-aF-9775A metabolic process +
                                is-aF-9775B metabolic process +
                                is-afibril organization +
                                is-afumitremorgin B metabolic process +
                                is-agalactose to glucose-1-phosphate metabolic process
                                is-agene silencing +
                                is-aglucose import in response to insulin stimulus +
                                is-aglycerol ether biosynthetic process +
                                is-aglycerol ether catabolic process
                                is-aglycolytic process +
                                is-ahalogenated hydrocarbon metabolic process +
                                is-aheme metabolic process +
                                is-ahydrogen peroxide catabolic process +
                                is-ainositol metabolic process +
                                is-ainositol phosphate metabolic process +
                                is-aintermediate filament-based process +
                                is-aL-arabinose catabolic process to xylulose 5-phosphate
                                is-alight absorption +
                                is-amacrolide metabolic process +
                                is-amaintenance of blood-brain barrier
                                is-amaintenance of location in cell +
                                is-amannose to fructose-6-phosphate metabolic process
                                is-aMAPK import into nucleus involved in conjugation with cellular fusion
                                is-aMAPK import into nucleus involved in innate immune response
                                is-amelanin metabolic process +
                                is-amembrane docking +
                                is-amesenchymal cell proliferation involved in prostate gland development +
                                is-amethyl tert-butyl ether metabolic process
                                is-amicroautophagy +
                                is-amicrotubule organizing center attachment site organization
                                is-amicrotubule-based process +
                                is-amineralocorticoid metabolic process +
                                is-amRNA export from nucleus in response to heat stress +
                                is-amycothiol metabolic process +
                                is-anicotinamide metabolic process +
                                is-anucleobase-containing small molecule metabolic process +
                                is-anucleoid organization +
                                is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                is-aommochrome metabolic process +
                                is-aone-carbon metabolic process +
                                is-aorcinol metabolic process +
                                is-aorganic acid metabolic process +
                                is-aorlandin metabolic process +
                                is-aoxidative RNA demethylation +
                                is-aoxytetracycline metabolic process +
                                is-apeptide pheromone export involved in conjugation with cellular fusion
                                is-apeptidoglycan biosynthetic process +
                                is-apeptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine
                                is-aperiplasmic space organization
                                is-aphenolic phthiocerol biosynthetic process
                                is-aphenylpropanoid metabolic process +
                                is-apheromone metabolic process +
                                is-aphotoreceptor cell outer segment organization
                                is-aphytochelatin metabolic process +
                                is-aphytol salvage
                                is-aplasma membrane fusion +
                                is-aplasma membrane organization involved in conjugation with cellular fusion
                                is-aplasmid maintenance +
                                is-aplastoglobule organization
                                is-apollen adhesion
                                is-apollen wall assembly +
                                is-apolythionate oxidation
                                is-apronuclear envelope synthesis +
                                is-aprotein demethylation +
                                is-aprotein glycosylation +
                                is-aprotein halogenation +
                                is-aprotein oxidation +
                                is-apteridine biosynthetic process
                                is-areceptor internalization [GO:0031623] (62 genes, 70 annotations)
                                        is-aB cell receptor internalization +
                                        is-aG-protein coupled receptor internalization
                                        is-ainsulin receptor internalization +
                                        negatively-regulatesnegative regulation of receptor internalization
                                        positively-regulatespositive regulation of receptor internalization
                                        is-areceptor internalization involved in canonical Wnt signaling pathway
                                        regulatesregulation of receptor internalization +
                                        is-aregulation of signal transduction by receptor internalization +
                                        is-aWnt receptor internalization +
                                is-aregulation of cellular component size +
                                is-aregulation of translational initiation by eIF2 alpha phosphorylation +
                                is-aremoval of superoxide radicals +
                                is-areplication fork processing +
                                is-areversion of cell type to default state involved in phenotypic switching
                                is-arhamnogalacturonan I biosynthetic process
                                is-arhodopsin metabolic process +
                                is-ariboflavin metabolic process +
                                is-aS-glycoside metabolic process +
                                is-asecretion by cell +
                                is-aSertoli cell proliferation
                                is-asiderophore metabolic process +
                                is-asignal maturation +
                                is-asignal transduction by phosphorylation +
                                is-asingle-celled organism vegetative growth phase +
                                is-asingle-organism intercellular transport +
                                is-asingle-organism organelle organization +
                                is-aspecification of ureteric bud anterior/posterior symmetry by BMP signaling pathway
                                is-asperm entry
                                is-aspore wall assembly +
                                is-astomatal movement +
                                is-asulfate reduction +
                                is-asulfide oxidation +
                                is-asulfur oxidation +
                                is-asynapse organization +
                                is-asyncytium formation +
                                is-atensidol A metabolic process +
                                is-aterminal button organization +
                                is-atetracycline metabolic process +
                                is-athiamine-containing compound metabolic process +
                                is-atoluene oxidation +
                                is-atoxin metabolic process +
                                is-atransmembrane transport +
                                is-atransposition +
                                is-aurea metabolic process +
                                is-averruculogen metabolic process +
                                is-avesicle targeting +
                                is-avesicle-mediated transport involved in floral organ abscission +
                                is-aviolaceol I metabolic process +
                                is-aviolaceol II metabolic process +
                                is-avistamycin metabolic process +
                                is-avitamin B6 metabolic process +
                                is-avitamin biosynthetic process +
                                is-avitamin catabolic process +
                                is-avitamin E metabolic process +
                                is-awybutosine biosynthetic process


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism metabolic process
                                is-aacetate ester metabolic process +
                                is-aactin modification +
                                is-aalkanesulfonate metabolic process +
                                is-aamyloid fibril formation
                                is-aaustinol metabolic process +
                                is-acarbon fixation +
                                is-acellular aldehyde metabolic process +
                                is-acellular alkane metabolic process +
                                is-acellular alkyne metabolic process +
                                is-acellular detoxification of nitrogen compound
                                is-achromosome condensation +
                                is-acoenzyme M metabolic process +
                                is-acyanide metabolic process +
                                is-ademethylation +
                                is-adimethyl sulfoxide metabolic process
                                is-aDNA damage induced protein phosphorylation
                                is-aDNA protection
                                is-aDNA repair +
                                is-adsRNA fragmentation +
                                is-aepidermal growth factor receptor ligand maturation +
                                is-afatty acid derivative metabolic process +
                                is-aglutathione derivative metabolic process +
                                is-aglycosyl compound metabolic process +
                                is-ahalogenated hydrocarbon metabolic process +
                                is-ahistone modification +
                                is-aisotype switching +
                                is-alipid metabolic process +
                                is-amaintenance of DNA repeat elements +
                                is-amating type switching +
                                is-ameiotic DNA double-strand break formation +
                                is-ameiotic gene conversion +
                                is-ameiotic heteroduplex formation
                                is-ameiotic strand displacement +
                                is-ameiotic strand invasion +
                                is-amitochondrial RNA processing +
                                is-amulticellular organismal metabolic process +
                                is-aoxidation-reduction process +
                                is-apatched ligand maturation
                                is-apigment metabolic process +
                                is-aprotein activation cascade +
                                is-areceptor internalization [GO:0031623] (62 genes, 70 annotations)
                                        is-aB cell receptor internalization +
                                        is-aG-protein coupled receptor internalization
                                        is-ainsulin receptor internalization +
                                        negatively-regulatesnegative regulation of receptor internalization
                                        positively-regulatespositive regulation of receptor internalization
                                        is-areceptor internalization involved in canonical Wnt signaling pathway
                                        regulatesregulation of receptor internalization +
                                        is-aregulation of signal transduction by receptor internalization +
                                        is-aWnt receptor internalization +
                                is-areciprocal meiotic recombination +
                                is-aregulation of translational initiation by eIF2 alpha phosphorylation +
                                is-aremoval of superoxide radicals +
                                is-areplication fork processing +
                                is-arespiratory burst +
                                is-aRNA-directed DNA methylation
                                is-asecondary metabolic process +
                                is-asignal transduction by phosphorylation +
                                is-asingle-organism biosynthetic process +
                                is-asingle-organism carbohydrate metabolic process +
                                is-asingle-organism catabolic process +
                                is-asmall molecule metabolic process +
                                is-asperm chromatin condensation +
                                is-atartrate metabolic process +
                                is-atelomere maintenance +
                                is-atransposition, DNA-mediated +
                                is-atransposon integration +
                                is-atRNA methylation in response to nitrogen starvation +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism transport
                                is-a2-aminoethylphosphonate transport
                                is-aacetate ester transport +
                                is-aalkane transport
                                is-aamide transport +
                                is-aamine transport +
                                is-acarbohydrate derivative transport +
                                is-acarbohydrate transport +
                                is-acargo loading into vesicle +
                                is-achaperone-mediated protein transport +
                                is-acofactor transport +
                                is-acutin transport
                                is-aDNA import into cell involved in transformation
                                is-adrug transport +
                                is-adsRNA transport
                                is-aeye pigment precursor transport
                                is-afatty acid derivative transport +
                                is-afatty-acyl group transport
                                is-afluid transport +
                                is-agas transport +
                                is-aglycoside transport +
                                is-ahormone transport +
                                is-ahydrogen transport +
                                is-aintestinal absorption +
                                is-aion transport +
                                is-airon coordination entity transport +
                                is-alactone transport
                                is-alipid hydroperoxide transport
                                is-alipid transport +
                                is-alipoprotein transport
                                is-amonoamine transport +
                                is-amultivesicular body sorting pathway
                                is-aneurotransmitter transport +
                                is-anitric oxide transport
                                is-anucleobase transport +
                                is-aone-carbon compound transport +
                                is-aorganic acid transport +
                                is-aorganic hydroxy compound transport +
                                is-aorganic phosphonate transport +
                                is-aorganophosphate ester transport +
                                is-aovarian nurse cell to oocyte transport +
                                is-aphagocytosis +
                                is-apigment granule transport +
                                is-apolyamine transport +
                                is-aprotein import +
                                is-aprotein transport across periplasmic space +
                                is-aprotein transport within extracellular region
                                is-aquaternary ammonium group transport +
                                is-areceptor internalization [GO:0031623] (62 genes, 70 annotations)
                                        is-aB cell receptor internalization +
                                        is-aG-protein coupled receptor internalization
                                        is-ainsulin receptor internalization +
                                        negatively-regulatesnegative regulation of receptor internalization
                                        positively-regulatespositive regulation of receptor internalization
                                        is-areceptor internalization involved in canonical Wnt signaling pathway
                                        regulatesregulation of receptor internalization +
                                        is-aregulation of signal transduction by receptor internalization +
                                        is-aWnt receptor internalization +
                                is-areceptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport
                                is-arRNA transport +
                                is-asecretion +
                                is-asilicate transport +
                                is-asingle-organism intercellular transport +
                                is-asingle-organism intracellular transport +
                                is-asingle-organism pinocytosis +
                                is-asnRNA transport +
                                is-asperm entry
                                is-asulfur compound transport +
                                is-asynaptic vesicle transport +
                                is-athioester transport +
                                is-atranscytosis +
                                is-atransepithelial transport +
                                is-atransmembrane transport +
                                is-atRNA transport +
                                is-aubiquitin-dependent endocytosis +
                                is-avascular transport +
                                is-avesicle transport along actin filament
                                is-avesicle-mediated transport involved in floral organ abscission +
                                is-avitamin transport +
                                is-axenobiotic transport +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory