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Term Detail
GO term:regulation of the force of heart contraction
Synonym: cardiac inotropy
Synonym: heart inotropy
GO id:GO:0002026
Definition:Any process that modulates the extent of heart contraction, changing the force with which blood is propelled.
Number of paths to term: 9

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of multicellular organismal process
                                        is-aregulation of system process
                                                is-aregulation of heart contraction
                                                        is-acardiac conduction +
                                                        is-anegative regulation of heart contraction +
                                                        is-apositive regulation of heart contraction +
                                                        is-aregulation of cardiac muscle contraction +
                                                        is-aregulation of heart contraction involved in acute-phase response
                                                        is-aregulation of heart rate +
                                                        is-aregulation of the force of heart contraction [GO:0002026] (26 genes, 33 annotations)
                                                                is-aregulation of the force of heart contraction by cardiac conduction
                                                                is-aregulation of the force of heart contraction by chemical signal +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-ahomeostatic process +
                                is-amaintenance of location +
                                is-amodification of morphology or physiology of other organism +
                                is-aregulation of aggregate size involved in sorocarp development +
                                is-aregulation of anatomical structure size +
                                is-aregulation of appetite +
                                is-aregulation of blood pressure +
                                is-aregulation of body fluid levels +
                                is-aregulation of brood size
                                is-aregulation of buoyancy
                                is-aregulation of cell shape +
                                is-aregulation of cilium beat frequency involved in ciliary motility
                                is-aregulation of circulating fibrinogen levels +
                                is-aregulation of female receptivity +
                                is-aregulation of heart rate +
                                is-aregulation of hormone levels +
                                is-aregulation of membrane lipid distribution +
                                is-aregulation of membrane permeability +
                                is-aregulation of membrane potential +
                                is-aregulation of muscle filament sliding speed +
                                is-aregulation of myofibril number
                                is-aregulation of neurotransmitter levels +
                                is-aregulation of nucleosome density
                                is-aregulation of protein stability +
                                is-aregulation of R8 cell spacing in compound eye +
                                is-aregulation of RNA stability +
                                is-aregulation of spindle density
                                is-aregulation of synapse structure and activity +
                                is-aregulation of synaptic plasticity +
                                is-aregulation of the force of heart contraction [GO:0002026] (26 genes, 33 annotations)
                                        is-aregulation of the force of heart contraction by cardiac conduction
                                        is-aregulation of the force of heart contraction by chemical signal +
                                is-aregulation of the velocity of shortening of skeletal muscle modulating contraction +
                                is-aregulation of translational fidelity +
                                is-aregulation of tube architecture, open tracheal system +
                                is-aregulation of tube diameter +
                                is-aregulation of tube length, open tracheal system
                                is-aregulation of vascular permeability +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-asystem process
                                        is-acirculatory system process
                                                is-ablood circulation
                                                        part-ofheart contraction
                                                                regulatesregulation of heart contraction
                                                                        is-acardiac conduction +
                                                                        is-anegative regulation of heart contraction +
                                                                        is-apositive regulation of heart contraction +
                                                                        is-aregulation of cardiac muscle contraction +
                                                                        is-aregulation of heart contraction involved in acute-phase response
                                                                        is-aregulation of heart rate +
                                                                        is-aregulation of the force of heart contraction [GO:0002026] (26 genes, 33 annotations)
                                                                                is-aregulation of the force of heart contraction by cardiac conduction
                                                                                is-aregulation of the force of heart contraction by chemical signal +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-asystem process
                                        is-acirculatory system process
                                                is-aheart process
                                                        is-aheart contraction
                                                                regulatesregulation of heart contraction
                                                                        is-acardiac conduction +
                                                                        is-anegative regulation of heart contraction +
                                                                        is-apositive regulation of heart contraction +
                                                                        is-aregulation of cardiac muscle contraction +
                                                                        is-aregulation of heart contraction involved in acute-phase response
                                                                        is-aregulation of heart rate +
                                                                        is-aregulation of the force of heart contraction [GO:0002026] (26 genes, 33 annotations)
                                                                                is-aregulation of the force of heart contraction by cardiac conduction
                                                                                is-aregulation of the force of heart contraction by chemical signal +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-asystem process
                                        regulatesregulation of system process
                                                is-aregulation of heart contraction
                                                        is-acardiac conduction +
                                                        is-anegative regulation of heart contraction +
                                                        is-apositive regulation of heart contraction +
                                                        is-aregulation of cardiac muscle contraction +
                                                        is-aregulation of heart contraction involved in acute-phase response
                                                        is-aregulation of heart rate +
                                                        is-aregulation of the force of heart contraction [GO:0002026] (26 genes, 33 annotations)
                                                                is-aregulation of the force of heart contraction by cardiac conduction
                                                                is-aregulation of the force of heart contraction by chemical signal +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of multicellular organismal process
                                is-aregulation of system process
                                        is-aregulation of heart contraction
                                                is-acardiac conduction +
                                                is-anegative regulation of heart contraction +
                                                is-apositive regulation of heart contraction +
                                                is-aregulation of cardiac muscle contraction +
                                                is-aregulation of heart contraction involved in acute-phase response
                                                is-aregulation of heart rate +
                                                is-aregulation of the force of heart contraction [GO:0002026] (26 genes, 33 annotations)
                                                        is-aregulation of the force of heart contraction by cardiac conduction
                                                        is-aregulation of the force of heart contraction by chemical signal +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-asystem process
                                        is-acirculatory system process
                                                is-ablood circulation
                                                        part-ofheart contraction
                                                                regulatesregulation of heart contraction
                                                                        is-acardiac conduction +
                                                                        is-anegative regulation of heart contraction +
                                                                        is-apositive regulation of heart contraction +
                                                                        is-aregulation of cardiac muscle contraction +
                                                                        is-aregulation of heart contraction involved in acute-phase response
                                                                        is-aregulation of heart rate +
                                                                        is-aregulation of the force of heart contraction [GO:0002026] (26 genes, 33 annotations)
                                                                                is-aregulation of the force of heart contraction by cardiac conduction
                                                                                is-aregulation of the force of heart contraction by chemical signal +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-asystem process
                                        is-acirculatory system process
                                                is-aheart process
                                                        is-aheart contraction
                                                                regulatesregulation of heart contraction
                                                                        is-acardiac conduction +
                                                                        is-anegative regulation of heart contraction +
                                                                        is-apositive regulation of heart contraction +
                                                                        is-aregulation of cardiac muscle contraction +
                                                                        is-aregulation of heart contraction involved in acute-phase response
                                                                        is-aregulation of heart rate +
                                                                        is-aregulation of the force of heart contraction [GO:0002026] (26 genes, 33 annotations)
                                                                                is-aregulation of the force of heart contraction by cardiac conduction
                                                                                is-aregulation of the force of heart contraction by chemical signal +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-asystem process
                                        regulatesregulation of system process
                                                is-aregulation of heart contraction
                                                        is-acardiac conduction +
                                                        is-anegative regulation of heart contraction +
                                                        is-apositive regulation of heart contraction +
                                                        is-aregulation of cardiac muscle contraction +
                                                        is-aregulation of heart contraction involved in acute-phase response
                                                        is-aregulation of heart rate +
                                                        is-aregulation of the force of heart contraction [GO:0002026] (26 genes, 33 annotations)
                                                                is-aregulation of the force of heart contraction by cardiac conduction
                                                                is-aregulation of the force of heart contraction by chemical signal +


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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory