Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ADAMTS3
  • Mouse genes Adamts3
  • Rat genes Adamts3
  • Zfish genes adamts3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adamts3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004175	endopeptidase activity	ADAMTS3	IDA		Human	PMID:24552833
Molecular Function	GO:0008233	peptidase activity	Adamts3	IDA		Mouse	PMID:16556917
Molecular Function	GO:0005515	protein binding	ADAMTS3	IPI	UniProtKB:Q6UXH8	Human	PMID:24552833
Molecular Function	GO:0005515	protein binding	ADAMTS3	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Cellular Component	GO:0070062	extracellular exosome	ADAMTS3	HDA		Human	PMID:19199708
Cellular Component	GO:0005615	extracellular space	ADAMTS3	IDA		Human	PMID:24552833
Biological Process	GO:0032964	collagen biosynthetic process	ADAMTS3	IDA		Human	PMID:11408482
Biological Process	GO:0001701	in utero embryonic development	Adamts3	IMP	MGI:MGI:5585728	Mouse	PMID:27996060
Biological Process	GO:0001946	lymphangiogenesis	adamts3	IGI	ZFIN:ZDB-GENO-220128-4	Zfish	PMID:32483144
Biological Process	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway	ADAMTS3	IDA		Human	PMID:24552833
Biological Process	GO:0016485	protein processing	ADAMTS3	IDA		Human	PMID:11408482
Biological Process	GO:0016485	protein processing	ADAMTS3	IDA		Human	PMID:24552833
Biological Process	GO:0016485	protein processing	Adamts3	IDA		Mouse	PMID:16556917
Biological Process	GO:0016485	protein processing	adamts3	IGI	ZFIN:ZDB-GENO-220128-4	Zfish	PMID:32483144
Biological Process	GO:0010573	vascular endothelial growth factor production	ADAMTS3	IDA		Human	PMID:24552833

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern