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Adamts3
Gene Detail
Symbol

Name
ID
Adamts3
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3
MGI:3045353
Synonyms
1100001H14Rik, 6330442E02Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 5
44.32 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:89673841-89883334 bp, - strand
From Ensembl annotation of GRCm38

  209494 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8596  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Adamts3

Human
homologs
Human Homolog ADAMTS3, ADAM metallopeptidase with thrombospondin type 1 motif, 3
NCBI Gene ID 9508
neXtProt AC  NX_O15072
Human Synonyms  ADAMTS-4
Human Chr (Location)  4q13.3; chr4:72280969-72568799 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Adamts3 interacts with 415 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (1)    Tissues (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 1
cDNA source data(27)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(29) cDNA(27) Primer pair(1) Other(1)
Microarray probesets(16)
Other database
links
Ensembl Gene ModelENSMUSG00000043635 (Evidence)
Entrez Gene330119 (Evidence)
UniGene133062
DFCITC1646374, TC1586989
DoTSDT.101709444, DT.55113645
NIA Mouse Gene IndexU057814, U254269
Consensus CDS ProjectCCDS39140.1, CCDS51542.1
International Mouse Knockout Project StatusAdamts3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000043635 Ensembl Gene Model | MGI Sequence Detail 209494 C57BL/6J ±  kb
transcript ENSMUST00000163159 Ensembl | MGI Sequence Detail 7582 Not Applicable 
polypeptide ENSMUSP00000132219 Ensembl | MGI Sequence Detail 1204 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(10) UniProt(10)
Polymorphisms
SNPs within 2kb(1631 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR010294 ADAM-TS Spacer 1
InterPro IPR024079 Metallopeptidase, catalytic domain
InterPro IPR001590 Peptidase M12B, ADAM/reprolysin
InterPro IPR013273 Peptidase M12B, ADAM-TS
InterPro IPR002870 Peptidase M12B, propeptide
InterPro IPR010909 PLAC
InterPro IPR000884 Thrombospondin, type 1 repeat
Protein Ontology PR:000003732 a disintegrin and metalloproteinase with thrombospondin motifs 3
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)
Other
accession IDs
MGI:1915676

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory